Targeting Amyloid Aggregation: An Overview of Strategies and Mechanisms von Giorgetti, Sofia, Greco, Claudio, Tortora, Paolo, Aprile, Francesco Antonio

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A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes von Ami, Diletta, Mereghetti, Paolo, Leri, Manuela, Giorgetti, Sofia, Natalello, Antonino, Doglia, Silvia Maria, Stefani, Massimo, Bucciantini, Monica

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Development of highly stable and de-immunized versions of recombinant alpha interferon: Promising candidates for the treatment of chronic and emerging viral diseases von Giorgetti, Sofía Inés, Etcheverrigaray, Marina, Terry, Frances, Martin, William, De Groot, Anne Searls, Ceaglio, Natalia, Oggero, Marcos, Mufarrege, Eduardo Federico

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Insights into a Protein-Nanoparticle System by Paramagnetic Perturbation NMR Spectroscopy von Hunashal, Yamanappa, Cantarutti, Cristina, Giorgetti, Sofia, Marchese, Loredana, Fogolari, Federico, Esposito, Gennaro

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Comparative study of the stabilities of synthetic in vitro and natural ex vivo transthyretin amyloid fibrils von Raimondi, Sara, Mangione, P. Patrizia, Verona, Guglielmo, Canetti, Diana, Nocerino, Paola, Marchese, Loredana, Piccarducci, Rebecca, Mondani, Valentina, Faravelli, Giulia, Taylor, Graham W., Gillmore, Julian D., Corazza, Alessandra, Pepys, Mark B., Giorgetti, Sofia, Bellotti, Vittorio

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Amyposomes, a nanotechnological chaperone with anti-amyloidogenic activity von Re, Francesca, Giorgetti, Sofia, Biondi, Barbara, Scapin, Stefano, Mantegazza, Francesco, Cassina, Valeria, Sesana, Silvia Maria, Rizzi, Laura, Eberini, Ivano, Palazzolo, Luca, Beeg, Marten, Gobbi, Marco, Sardina, Marco, Masserini, Massimo

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Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis von Mangione, P. Patrizia, Porcari, Riccardo, Gillmore, Julian D., Pucci, Piero, Monti, Maria, Porcari, Mattia, Giorgetti, Sofia, Marchese, Loredana, Raimondi, Sara, Serpell, Louise C., Chen, Wenjie, Relini, Annalisa, Marcoux, Julien, Clatworthy, Innes R., Taylor, Graham W., Tennent, Glenys A., Robinson, Carol V., Hawkins, Philip N., Stoppini, Monica, Wood, Stephen P., Pepys, Mark B., Bellotti, Vittorio

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In situ characterization of protein aggregates in human tissues affected by light chain amyloidosis: a FTIR microspectroscopy study von Ami, Diletta, Lavatelli, Francesca, Rognoni, Paola, Palladini, Giovanni, Raimondi, Sara, Giorgetti, Sofia, Monti, Luca, Doglia, Silvia Maria, Natalello, Antonino, Merlini, Giampaolo

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A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis von Marcoux, Julien, Mangione, P Patrizia, Porcari, Riccardo, Degiacomi, Matteo T, Verona, Guglielmo, Taylor, Graham W, Giorgetti, Sofia, Raimondi, Sara, Sanglier‐Cianférani, Sarah, Benesch, Justin LP, Cecconi, Ciro, Naqvi, Mohsin M, Gillmore, Julian D, Hawkins, Philip N, Stoppini, Monica, Robinson, Carol V, Pepys, Mark B, Bellotti, Vittorio

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Hereditary Systemic Amyloidosis Due to Asp76Asn Variant β2-Microglobulin von Valleix, Sophie, Gillmore, Julian D, Bridoux, Frank, Mangione, Palma P, Dogan, Ahmet, Nedelec, Brigitte, Boimard, Mathieu, Touchard, Guy, Goujon, Jean-Michel, Lacombe, Corinne, Lozeron, Pierre, Adams, David, Lacroix, Catherine, Maisonobe, Thierry, Planté-Bordeneuve, Violaine, Vrana, Julie A, Theis, Jason D, Giorgetti, Sofia, Porcari, Riccardo, Ricagno, Stefano, Bolognesi, Martino, Stoppini, Monica, Delpech, Marc, Pepys, Mark B, Hawkins, Philip N, Bellotti, Vittorio

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Atomic structure of a nanobody-trapped domain-swapped dimer of an amyloidogenic β2-microglobulin variant von Domanska, Katarzyna, Vanderhaegen, Saskia, Srinivasan, Vasundara, Pardon, Els, Dupeux, Florine, Marquez, Jose A, Giorgetti, Sofia, Stoppini, Monica, Wyns, Lode, Bellotti, Vittorio, Steyaert, Jan

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Citrate-stabilized gold nanoparticles hinder fibrillogenesis of a pathological variant of β2-microglobulin von Cantarutti, Cristina, Raimondi, Sara, Brancolini, Giorgia, Corazza, Alessandra, Giorgetti, Sofia, Ballico, Maurizio, Zanini, Stefano, Palmisano, Giovanni, Bertoncin, Paolo, Marchese, Loredana, Patrizia Mangione, P, Bellotti, Vittorio, Corni, Stefano, Fogolari, Federico, Esposito, Gennaro

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Inhibition of the mechano-enzymatic amyloidogenesis of transthyretin: role of ligand affinity, binding cooperativity and occupancy of the inner channel von Verona, Guglielmo, Mangione, P. Patrizia, Raimondi, Sara, Giorgetti, Sofia, Faravelli, Giulia, Porcari, Riccardo, Corazza, Alessandra, Gillmore, Julian D., Hawkins, Philip N., Pepys, Mark B., Taylor, Graham W., Bellotti, Vittorio

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C. elegans expressing D76N β2-microglobulin: a model for in vivo screening of drug candidates targeting amyloidosis von Faravelli, Giulia, Raimondi, Sara, Marchese, Loredana, Partridge, Frederick A., Soria, Cristina, Mangione, P. Patrizia, Canetti, Diana, Perni, Michele, Aprile, Francesco A., Zorzoli, Irene, Di Schiavi, Elia, Lomas, David A., Bellotti, Vittorio, Sattelle, David B., Giorgetti, Sofia

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Biochemical and Electrophysiological Modification of Amyloid Transthyretin on Cardiomyocytes von Sartiani, Laura, Bucciantini, Monica, Spinelli, Valentina, Leri, Manuela, Natalello, Antonino, Nosi, Daniele, Maria Doglia, Silvia, Relini, Annalisa, Penco, Amanda, Giorgetti, Sofia, Gerace, Elisabetta, Mannaioni, Guido, Bellotti, Vittorio, Rigacci, Stefania, Cerbai, Elisabetta, Stefani, Massimo

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Effect of Tetracyclines on the Dynamics of Formation and Destructuration of β2-Microglobulin Amyloid Fibrils von Giorgetti, Sofia, Raimondi, Sara, Pagano, Katiuscia, Relini, Annalisa, Bucciantini, Monica, Corazza, Alessandra, Fogolari, Federico, Codutti, Luca, Salmona, Mario, Mangione, Palma, Colombo, Lino, De Luigi, Ada, Porcari, Riccardo, Gliozzi, Alessandra, Stefani, Massimo, Esposito, Gennaro, Bellotti, Vittorio, Stoppini, Monica

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Calcium Binds to Transthyretin with Low Affinity von Cantarutti, Cristina, Mimmi, Maria Chiara, Verona, Guglielmo, Mandaliti, Walter, Taylor, Graham W, Mangione, P. Patrizia, Giorgetti, Sofia, Bellotti, Vittorio, Corazza, Alessandra

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Heparin Strongly Enhances the Formation of β2-Microglobulin Amyloid Fibrils in the Presence of Type I Collagen von Relini, Annalisa, De Stefano, Silvia, Torrassa, Silvia, Cavalleri, Ornella, Rolandi, Ranieri, Gliozzi, Alessandra, Giorgetti, Sofia, Raimondi, Sara, Marchese, Loredana, Verga, Laura, Rossi, Antonio, Stoppini, Monica, Bellotti, Vittorio

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Human wild-type and D76N β2-microglobulin variants are significant proteotoxic and metabolic stressors for transgenic C. elegans von Raimondi, Sara, Faravelli, Giulia, Nocerino, Paola, Mondani, Valentina, Baruffaldi, Alma, Marchese, Loredana, Mimmi, Maria Chiara, Canetti, Diana, Verona, Guglielmo, Caterino, Marianna, Ruoppolo, Margherita, Mangione, P Patrizia, Bellotti, Vittorio, Lavatelli, Francesca, Giorgetti, Sofia

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Collagen Plays an Active Role in the Aggregation of β2-Microglobulin under Physiopathological Conditions of Dialysis-related Amyloidosis von Relini, Annalisa, Canale, Claudio, De Stefano, Silvia, Rolandi, Ranieri, Giorgetti, Sofia, Stoppini, Monica, Rossi, Antonio, Fogolari, Federico, Corazza, Alessandra, Esposito, Gennaro, Gliozzi, Alessandra, Bellotti, Vittorio

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