Improved Outcome in Children With Newly Diagnosed High-Risk Neuroblastoma Treated With Chemoimmunotherapy: Updated Results of a Phase II Study Using hu14.18K322A von Furman, Wayne L, McCarville, Beth, Shulkin, Barry L, Davidoff, Andrew, Krasin, Matthew, Hsu, Chia-Wei, Pan, Haitao, Wu, Jianrong, Brennan, Rachel, Bishop, Michael W, Helmig, Sara, Stewart, Elizabeth, Navid, Fariba, Triplett, Brandon, Santana, Victor, Santiago, Teresa, Hank, Jacquelyn A, Gillies, Stephen D, Yu, Alice, Sondel, Paul M, Leung, Wing H, Pappo, Alberto, Federico, Sara M

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Evaluating natural killer cell cytotoxicity against solid tumors using a microfluidic model von Ayuso, Jose M., Truttschel, Regan, Gong, Max M., Humayun, Mouhita, Virumbrales-Munoz, Maria, Vitek, Ross, Felder, Mildred, Gillies, Stephen D., Sondel, Paul, Wisinski, Kari B., Patankar, Manish, Beebe, David J., Skala, Melissa C.

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A new platform for constructing antibody-cytokine fusion proteins (immunocytokines) with improved biological properties and adaptable cytokine activity von Gillies, Stephen D.

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In Situ Tumor Vaccination by Combining Local Radiation and Tumor-Specific Antibody or Immunocytokine Treatments von Morris, Zachary S, Guy, Emily I, Francis, David M, Gressett, Monica M, Werner, Lauryn R, Carmichael, Lakeesha L, Yang, Richard K, Armstrong, Eric A, Huang, Shyhmin, Navid, Fariba, Gillies, Stephen D, Korman, Alan, Hank, Jacquelyn A, Rakhmilevich, Alexander L, Harari, Paul M, Sondel, Paul M

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A Phase II Trial of Hu14.18K322A in Combination with Induction Chemotherapy in Children with Newly Diagnosed High-Risk Neuroblastoma von Furman, Wayne L, Federico, Sara M, McCarville, Mary Beth, Shulkin, Barry L, Davidoff, Andrew M, Krasin, Matthew J, Sahr, Natasha, Sykes, April, Wu, Jianrong, Brennan, Rachel C, Bishop, Michael William, Helmig, Sara, Stewart, Elizabeth, Navid, Fariba, Triplett, Brandon, Santana, Victor M, Bahrami, Armita, Anthony, Gwendolyn, Yu, Alice L, Hank, Jacquelyn, Gillies, Stephen D, Sondel, Paul M, Leung, Wing H, Pappo, Alberto S

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A Low-Toxicity IL-2―Based Immunocytokine Retains Antitumor Activity Despite Its High Degree of IL-2 Receptor Selectivity von GILLIES, Stephen D, YAN LAN, HETTMANN, Thore, BRUNKHORST, Beatrice, YAPING SUN, MUELLER, Stefan O, LO, Kin-Ming

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NK cells engineered to express a GD2‐specific antigen receptor display built‐in ADCC‐like activity against tumour cells of neuroectodermal origin von Esser, Ruth, Müller, Tina, Stefes, Dörthe, Kloess, Stephan, Seidel, Diana, Gillies, Stephen D., Aperlo‐Iffland, Christel, Huston, James S., Uherek, Christoph, Schönfeld, Kurt, Tonn, Torsten, Huebener, Nicole, Lode, Holger N., Koehl, Ulrike, Wels, Winfried S.

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Combined innate and adaptive immunotherapy overcomes resistance of immunologically cold syngeneic murine neuroblastoma to checkpoint inhibition von Voeller, Julie, Erbe, Amy K., Slowinski, Jacob, Rasmussen, Kayla, Carlson, Peter M., Hoefges, Anna, VandenHeuvel, Sabrina, Stuckwisch, Ashley, Wang, Xing, Gillies, Stephen D., Patel, Ravi B., Farrel, Alvin, Rokita, Jo Lynne, Maris, John, Hank, Jacquelyn A., Morris, Zachary S., Rakhmilevich, Alexander L., Sondel, Paul M.

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Tumor-targeted IL-12 combined with local irradiation leads to systemic tumor control via abscopal effects in vivo von Eckert, Franziska, Jelas, Ivan, Oehme, Moritz, Huber, Stephan M., Sonntag, Katja, Welker, Christian, Gillies, Stephen D., Strittmatter, Wolfgang, Zips, Daniel, Handgretinger, Rupert, Schilbach, Karin

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Genotypes of NK Cell KIR Receptors, Their Ligands, and Fcγ Receptors in the Response of Neuroblastoma Patients to Hu14.18-IL2 Immunotherapy von DELGADO, David C, HANK, Jacquelyn A, YANG, Richard, GADBAW, Brian, DESANTES, Kenneth B, LONDON, Wendy B, SEEGER, Robert C, MARIS, John M, SENDEL, Paul M, KOLESAR, Jill, LORENTZEN, David, GAN, Jacek, SEO, Songwon, KIM, Kyungmann, SHUSTERMAN, Suzanne, GILLIES, Stephen D, REISFELD, Ralph A

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Neuroblastoma Patients' KIR and KIR-Ligand Genotypes Influence Clinical Outcome for Dinutuximab-based Immunotherapy: A Report from the Children's Oncology Group von Erbe, Amy K, Wang, Wei, Carmichael, Lakeesha, Kim, KyungMann, Mendonça, Eneida A, Song, Yiqiang, Hess, Dustin, Reville, Patrick K, London, Wendy B, Naranjo, Arlene, Hank, Jacquelyn A, Diccianni, Mitchell B, Reisfeld, Ralph A, Gillies, Stephen D, Matthay, Katherine K, Cohn, Susan L, Hogarty, Michael D, Maris, John M, Park, Julie R, Ozkaynak, M Fevzi, Gilman, Andrew L, Yu, Alice L, Sondel, Paul M

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Inhibition of Plaque Neovascularization Reduces Macrophage Accumulation and Progression of Advanced Atherosclerosis von Moulton, Karen S., Vakili, Khashayar, Zurakowsk, David, Soliman, Mohsin, Butterfield, Catherine, Sylvin, Erik, Lo, Kin-Ming, Gillies, Stephen, Javaherian, Kashi, Folkman, Judah

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Tumor-Specific Inhibition of In Situ Vaccination by Distant Untreated Tumor Sites von Morris, Zachary S, Guy, Emily I, Werner, Lauryn R, Carlson, Peter M, Heinze, Clinton M, Kler, Jasdeep S, Busche, Sara M, Jaquish, Abigail A, Sriramaneni, Raghava N, Carmichael, Lakeesha L, Loibner, Hans, Gillies, Stephen D, Korman, Alan J, Erbe, Amy K, Hank, Jacquelyn A, Rakhmilevich, Alexander L, Harari, Paul M, Sondel, Paul M

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Human and murine IL2 receptors differentially respond to the human-IL2 component of immunocytokines von Perez Horta, Zulmarie, Saseedhar, Swetha, Rakhmilevich, Alexander L., Carmichael, Lakeesha, Hank, Jacquelyn A., Boyden, Margaret, Gillies, Stephen D., Sondel, Paul M.

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Anti-GD(2) with an FC point mutation reduces complement fixation and decreases antibody-induced allodynia von Sorkin, Linda S, Otto, Mario, Baldwin, 3rd, William M, Vail, Emily, Gillies, Stephen D, Handgretinger, Rupert, Barfield, Raymond C, Yu, Hui Ming, Yu, Alice L

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Short-course neoadjuvant in situ vaccination for murine melanoma von Aiken, Taylor J, Komjathy, David, Rodriguez, Matthew, Stuckwisch, Ashley, Feils, Arika, Subbotin, Vladimir, Birstler, Jen, Gillies, Stephen D, Rakhmilevich, Alexander L, Erbe, Amy K, Sondel, Paul M

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Intratumoral hu14.18-IL-2 (IC) induces local and systemic antitumor effects that involve both activated T and NK cells as well as enhanced IC retention von Yang, Richard K, Kalogriopoulos, Nicholas A, Rakhmilevich, Alexander L, Ranheim, Erik A, Seo, Songwon, Kim, Kyungmann, Alderson, Kory L, Gan, Jacek, Reisfeld, Ralph A, Gillies, Stephen D, Hank, Jacquelyn A, Sondel, Paul M

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Intratumoral treatment of smaller mouse neuroblastoma tumors with a recombinant protein consisting of IL-2 linked to the Hu14.18 antibody increases intratumoral CD8+ T and NK cells... von Yang, Richard K., Kalogriopoulos, Nicholas A., Rakhmilevich, Alexander L., Ranheim, Erik A., Seo, Songwon, Kim, KyungMann, Alderson, Kory L., Gan, Jacek, Reisfeld, Ralph A., Gillies, Stephen D., Hank, Jacquelyn A., Sondel, Paul M.

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Phase I Clinical Trial of the Immunocytokine EMD 273063 in Melanoma Patients von KING, David M, ALBERTINI, Mark R, EICKHOFF, Jens, KENDRA, Kari, REISFELD, Ralph, GILLIES, Stephen D, SONDEL, Paul, SCHALCH, Heidi, HANK, Jacquelyn A, GAN, Jacek, SURFUS, Jean, MAHVI, David, SCHILLER, Joan H, WARNER, Thomas, KIM, Kyungmann

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Radiofrequency Ablation Combined with KS-IL2 Immunocytokine (EMD 273066) Results in an Enhanced Antitumor Effect against Murine Colon Adenocarcinoma von JOHNSON, Erik E, YAMANE, Brett H, BUHTOIAROV, Ilia N, LUM, Hillary D, RAKHMILEVICH, Alexander L, MAHVI, David M, GILLIES, Stephen D, SONDEL, Paul M

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