Discovery and mechanism of ustekinumab: A human monoclonal antibody targeting interleukin-12 and interleukin-23 for treatment of immune-mediated disorders von Benson, Jacqueline M., Peritt, David, Scallon, Bernard J., Heavner, George A., Shealy, David J., Giles-Komar, Jill M., Mascelli, Mary Ann

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Characterization of golimumab, a human monoclonal antibody specific for human tumor necrosis factor α von Shealy, David J., Cai, Ann, Staquet, Kim, Baker, Audrey, Lacy, Eilyn R., Johns, Laura, Vafa, Omid, Gunn, George, Tam, Susan, Sague, Sarah, Wang, Dana, Brigham-Burke, Mike, Dalmonte, Paul, Emmell, Eva, Pikounis, Bill, Bugelski, Peter J., Zhou, Honghui, Scallon, Bernard J., Giles-Komar, Jill M.

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Development of the IL-12/23 antagonist ustekinumab in psoriasis: past, present, and future perspectives von Yeilding, Newman, Szapary, Philippe, Brodmerkel, Carrie, Benson, Jacqueline, Plotnick, Michael, Zhou, Honghui, Goyal, Kavitha, Schenkel, Brad, Giles-Komar, Jill, Mascelli, Mary Ann, Guzzo, Cynthia

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Development of the IL-12/23 antagonist ustekinumab in psoriasis: past, present, and future perspectives - an update von Yeilding, Newman, Szapary, Philippe, Brodmerkel, Carrie, Benson, Jacqueline, Plotnick, Michael, Zhou, Honghui, Goyal, Kavitha, Schenkel, Brad, Giles-Komar, Jill, Mascelli, Mary Ann, Guzzo, Cynthia

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Human and Non-Human Primate Intestinal FcRn Expression and Immunoglobulin G Transcytosis von Hornby, Pamela J., Cooper, Philip R., Kliwinski, Connie, Ragwan, Edwin, Mabus, John R., Harman, Benjamin, Thompson, Suzanne, Kauffman, Amanda L., Yan, Zhengyin, Tam, Susan H., Dorai, Haimanti, Powers, Gordon D., Giles-Komar, Jill

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Discovering Molecules That Regulate Efferocytosis Using Primary Human Macrophages and High Content Imaging von Santulli-Marotto, Sandra, Gervais, Alexis, Fisher, Jamie, Strake, Brandy, Ogden, Carol Anne, Riveley, Chelsea, Giles-Komar, Jill

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Solubility evaluation of murine hybridoma antibodies von Spencer, Stacey, Bethea, Deidra, Raju, T. Shantha, Giles-Komar, Jill, Feng, Yiqing

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CNTO 95, a fully human monoclonal antibody that inhibits αv integrins, has antitumor and antiangiogenic activity in vivo von Trikha, Mohit, Zhou, Zhao, Nemeth, Jeffrey A., Chen, Qiming, Sharp, Celia, Emmell, Eva, Giles‐Komar, Jill, Nakada, Marian T.

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Chemokine (C-C motif) ligand 2 mediates direct and indirect fibrotic responses in human and murine cultured fibrocytes von Ekert, Jason E, Murray, Lynne A, Das, Anuk M, Sheng, Hai, Giles-Komar, Jill, Rycyzyn, Michael A

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High expression of RELP (Reg IV) in neoplastic goblet cells of appendiceal mucinous cystadenoma and pseudomyxoma peritonei von HEISKALA, Kukka, GILES-KOMAR, Jill, HEISKALA, Marja, ANDERSSON, Leif C

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A novel site contributing to growth-arrest-specific gene 6 binding to its receptors as revealed by a human monoclonal antibody von Fisher, Paul W, Brigham-Burke, Michael, Wu, Sheng-Jiun, Luo, Jinquan, Carton, Jill, Staquet, Kim, Gao, Wei, Jackson, Sheila, Bethea, Deidra, Chen, Cailin, Hu, Bing, Giles-Komar, Jill, Yang, Jing

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Down modulation of human TLR3 function by a monoclonal antibody von Duffy, Karen E., Lamb, Roberta J., San Mateo, Lani R., Jordan, Jarrat L., Canziani, Gabriela, Brigham-Burke, Michael, Korteweg, Jeremy, Cunningham, Mark, Beck, Heena Solanki, Carton, Jill, Giles-Komar, Jill, Duchala, Cynthia, Sarisky, Robert T., Mbow, M. Lamine

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Generation and characterization of rat anti-mouse ST2L monoclonal antibodies von Fursov, Natalie, Johnston, Erin, Duffy, Karen, Cotty, Adam, Petley, Theodore, Fisher, Jamie, Jiang, Haiyan, Rycyzyn, Michael A, Giles-Komar, Jill, Powers, Gordon

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Anti-IL-13 monoclonal antibody inhibits airway hyperresponsiveness, inflammation and airway remodeling von Yang, Gaoyun, Volk, Amy, Petley, Ted, Emmell, Eva, Giles-Komar, Jill, Shang, Xiaozhou, Li, Jian, Das, Anuk M., Shealy, Dave, Griswold, Don E., Li, Li

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Pharmacodynamic enhancement of the anti-platelet antibody Fab abciximab by site-specific pegylation von Knight, David M., Jordan, Robert E., Kruszynski, Marian, Tam, Susan H., Giles-Komar, Jill, Treacy, George, Heavner, George A.

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The Fully Human Antibody CNTO1275 Effectively Inhibits Human IL-12 and IL-23 Mediated Th1 and Th17 Cell Function and Provides Clinical Benefit to Patients with Plaque Psoriasis von Benson, Jacqueline, Assistant Director, Centocor Research and Development, Discovery Research, Radnor, PA, Orlovsky, Yevgeniya, Senior Associate Scientist, Centocor Research and Development, Radnor, PA, Staquet, Kim, Manager, Centocor Research and Development, Radnor, PA, Luo, Jinquan, Principal Research Scientist, Centocor Research and Development, Radnor, PA, Branigan, Patrick, Research Scientist, Centocor Research and Development, Radnor, PA, Lamb, Roberta, Senior Associate Scientist, Centocor Research and Development, Radnor, PA, Li, Jian, Research Scientist, Centocor Research and Development, Radnor, PA, Capocasale, Renold, Research Scientist, Centocor, Radnor, PA, Huber, Janine, Senior Associate Scientist, Therakos, Exton, PA, Scallon, Bernie, Sr Research Fellow, Centocor, Radnor, PA, Peritt, David, Director, Therakos, Exton, PA, David Shealy, Senior Research Fellow, Centocor Research and Development, Radnor, PA, Heavner, George, Distinguished Research Fellow, Centocor Research and Development, Radnor, PA, Giles-Komar, Jill, Director, Centocor Research and Development, Radnor, PA, Nesspor, Tom, Senior Associate Scientist, Centocor, Radnor, PA

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Abstract 3518: Flow cytometry as a single platform tool to evaluate multiple mechanisms of actions of therapeutic antibodies von Chadderton, Antony R., Harvey, Shane, Strake, Brandy, Giles-Komar, Jill, Capocasale, Renold J., Raju, T. Shantha

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Development and utilization of activated STAT3 detection assays for screening a library of secreted proteins von Fursov, Natalie, Gates, Irina V, Panavas, Tadas, Giles-Komar, Jill, Powers, Gordon

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The Role of FcRn in Monoclonal Antibody Serum Uptake from the Intestine in Suckling Rat Pups von Cooper, Philip R, Kliwinski, Connie, Perkinson, Robert, Mabus, John, Giles‐Komar, Jill, Hornby, Pamela

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FcRn Expression and Antibody Transcytosis in Adult Human and Non‐Human Primate Intestine von Hornby, Pamela Janet, Cooper, Philip R, Kliwinski, Connie, Ragwan, Edwin, Mabus, John R, Harman, Benjamin, Dorai, Haimanti, Giles‐Komar, Jill

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