What can cell biology tell us about heterogeneity in lysosomal storage diseases? von Gieselmann, V

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Crystal Structure of Human Arylsulfatase A:  The Aldehyde Function and the Metal Ion at the Active Site Suggest a Novel Mechanism for Sulfate Ester Hydrolysis von Lukatela, G, Krauss, N, Theis, K, Selmer, T, Gieselmann, V, von Figura, K, Saenger, W

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Lysosomal sulfatide storage in the brain of arylsulfatase A-deficient mice: cellular alterations and topographic distribution von Wittke, D, Hartmann, D, Gieselmann, V, Lüllmann-Rauch, R

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Late-onset metachromatic leukodystrophy : Genotype strongly influences phenotype von RAUSCHKA, H, COLSCH, B, KRIVIT, W, MOSER, H, MOSER, A, GIESELMANN, V, ZALC, B, COX, T, REUNER, U, TYLKI-SZYMANSKA, A, ABOUL-ENEIN, F, LEGUERN, E, BAUMANN, N, BERNHEIMER, H, BERGER, J, WEVERS, R, SCHMIDBAUER, M, KRAMMER, M, TURPIN, J.-C, LEFEVRE, M, OLIVIER, C, TARDIEU, S

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Partial cure of established disease in an animal model of metachromatic leukodystrophy after intracerebral adeno-associated virus-mediated gene transfer von SEVIN, C, VEROT, L, AUBOURG, P, CARTIER, N, BENRAISS, A, VAN DAM, D, BONNIN, D, NAGELS, G, FOUQUET, F, GIESELMANN, V, VANIER, M. T, DE DEYN, P. P

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Specific downregulation and mistargeting of the lipid raft-associated protein MAL in a glycolipid storage disorder von Saravanan, K, Schaeren-Wiemers, N, Klein, D, Sandhoff, R, Schwarz, A, Yaghootfam, A, Gieselmann, V, Franken, S

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Embryonic stem cell-based reduction of central nervous system sulfatide storage in an animal model of metachromatic leukodystrophy von KLEIN, D, SCHMANDT, T, MUTH-KÖHNE, E, PEREZ-BOUZA, A, SEGSCHNEIDER, M, GIESELMANN, V, BRÜSTLE, O

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Lysosulfatide Regulates the Motility of a Neural Precursor Cell Line Via Calcium-mediated Process Collapse von Hans, M., Pusch, A., Dai, L., Racké, K., Swandulla, D., Gieselmann, V., Kappler, J.

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Specific hammerhead ribozymes reduce synthesis of cation-independent mannose 6-phosphate receptor mRNA and protein von YAGHOOTFAM, A, GIESELMANN, V

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Bone marrow stem cell-based gene transfer in a mouse model for metachromatic leukodystrophy: effects on visceral and nervous system disease manifestations von MATZNER, U, HARTMANN, D, LÜLLMANN-RAUCH, R, COENEN, R, ROTHERT, F, MANSSON, J.-E, FREDMAN, P, D'HOOGE, R, DE DEYN, P. P, GIESELMANN, V

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Retrovirally expressed human arylsulfatase A corrects the metabolic defect of arylsulfatase A-deficient mouse cells von MATZNER, U, HABETHA, M, GIESELMANN, V

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Intracerebroventricular enzyme infusion corrects central nervous system pathology and dysfunction in a mouse model of metachromatic leukodystrophy von Stroobants, Stijn, Gerlach, Debora, Matthes, Frank, Hartmann, Dieter, Fogh, Jens, Gieselmann, Volkmar, D'Hooge, Rudi, Matzner, Ulrich

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Efficacy of enzyme replacement therapy in an aggravated mouse model of metachromatic leukodystrophy declines with age von MATTHES, Frank, STROOBANTS, Stijn, GERLACH, Debora, WOHLENBERG, Claudia, WESSIG, Carsten, FOGH, Jens, GIESELMANN, Volkmar, ECKHARDT, Matthias, D'HOOGE, Rudi, MATZNER, Ulrich

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Long-term expression and transfer of arylsulfatase A into brain of arylsulfatase A-deficient mice transplanted with bone marrow expressing the arylsulfatase A cDNA from a retrovira... von MATZNER, U, HARZER, K, LEARISH, R. D, BARRANGER, J. A, GIESELMANN, V

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Bone marrow stem cell-based gene transfer in a mouse model for metachromatic leukodystrophy: effects on visceral and nervous system disease manifestations von Matzner, U, Hartmann, D, Luellmann-Rauch, R, Coenen, R, Rothert, F, Maensson, J-E, Fredman, P, D'Hooge, R, De Deyn, PP, Gieselmann, V

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Lysosomal sulfoglycolipid storage in the kidneys of mice deficient for arylsulfatase A (ASA) and of double-knockout mice deficient for ASA and galactosylceramide synthase von Lüllmann-Rauch, R, Matzner, U, Franken, S, Hartmann, D, Gieselmann, V

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Metachromatic leukodystrophy: Molecular genetics and an animal model von Gieselmann, V., Matzner, U., Hess, B., Lüllmann‐Rauch, R., Coenen, R., Hartmann, D., D'Hooge, R., Dedeyn, P., Nagels, G.

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SPHINGOLIPIDS IN PHYSIOLOGY AND PATHOPHYSIOLOGY von Gieselmann, V

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A mammalian fatty acid hydroxylase responsible for the formation of alpha-hydroxylated galactosylceramide in myelin von Eckhardt, Matthias, Yaghootfam, Afshin, Fewou, Simon N, Zöller, Inge, Gieselmann, Volkmar

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Morphological alterations in the inner ear of the arylsulfatase A-deficient mouse von COENEN, R, GIESELMANN, V, LÜLLMANN-RAUCH, R

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