Site-Specific Antibody–Drug Conjugation through Glycoengineering von Zhou, Qun, Stefano, James E, Manning, Charlene, Kyazike, Josephine, Chen, Bo, Gianolio, Diego A, Park, Anna, Busch, Michelle, Bird, Julie, Zheng, Xiaoyang, Simonds-Mannes, Helene, Kim, Jennifer, Gregory, Rick C, Miller, Robert J, Brondyk, William H, Dhal, Pradeep K, Pan, Clark Q

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Cabazitaxel is more active than first-generation taxanes in ABCB1(+) cell lines due to its reduced affinity for P-glycoprotein von Duran, George E., Derdau, Volker, Weitz, Dietmar, Philippe, Nicolas, Blankenstein, Jörg, Atzrodt, Jens, Sémiond, Dorothée, Gianolio, Diego A., Macé, Sandrine, Sikic, Branimir I.

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Anti-Endosialin Antibody-Drug Conjugate: Potential in Sarcoma and Other Malignancies von Rouleau, Cecile, Gianolio, Diego A, Smale, Robert, Roth, Stephanie D, Krumbholz, Roy, Harper, Jay, Munroe, Kenneth J, Green, Tessa L, Horten, Bruce C, Schmid, Steven M, Teicher, Beverly A

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Ivosidenib and Azacitidine in IDH1-Mutated Acute Myeloid Leukemia von Montesinos, Pau, Recher, Christian, Vives, Susana, Zarzycka, Ewa, Wang, Jianxiang, Bertani, Giambattista, Heuser, Michael, Calado, Rodrigo T, Schuh, Andre C, Yeh, Su-Peng, Daigle, Scott R, Hui, Jianan, Pandya, Shuchi S, Gianolio, Diego A, de Botton, Stephane, Döhner, Hartmut

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Mutant Isocitrate Dehydrogenase 1 Inhibitor Ivosidenib in Combination With Azacitidine for Newly Diagnosed Acute Myeloid Leukemia von DiNardo, Courtney D, Stein, Anthony S, Stein, Eytan M, Fathi, Amir T, Frankfurt, Olga, Schuh, Andre C, Döhner, Hartmut, Martinelli, Giovanni, Patel, Prapti A, Raffoux, Emmanuel, Tan, Peter, Zeidan, Amer M, de Botton, Stéphane, Kantarjian, Hagop M, Stone, Richard M, Frattini, Mark G, Lersch, Frederik, Gong, Jing, Gianolio, Diego A, Zhang, Vickie, Franovic, Aleksandra, Fan, Bin, Goldwasser, Meredith, Daigle, Scott, Choe, Sung, Wu, Bin, Winkler, Thomas, Vyas, Paresh

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Taxane resistance in prostate cancer is mediated by decreased drug-target engagement von Gjyrezi, Ada, Xie, Fang, Voznesensky, Olga, Khanna, Prateek, Calagua, Carla, Bai, Yang, Kung, Justin, Wu, Jim, Corey, Eva, Montgomery, Bruce, Mace, Sandrine, Gianolio, Diego A, Bubley, Glenn J, Balk, Steven P, Giannakakou, Paraskevi, Bhatt, Rupal S

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Convergent synthesis of hydrophilic monomethyl dolastatin 10 based drug linkers for antibody-drug conjugation von Yang, Kanwen, Chen, Bo, Gianolio, Diego A, Stefano, James E, Busch, Michelle, Manning, Charlene, Alving, Kim, Gregory, Richard C, Brondyk, William H, Miller, Robert J, Dhal, Pradeep K

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Design, Synthesis, and in vitro Evaluation of Multivalent Drug Linkers for High‐Drug‐Load Antibody–Drug Conjugates von Chen, Bo, Gianolio, Diego A., Stefano, James E., Manning, Charlene M., Gregory, Richard C., Busch, Michelle M., Brondyk, William H., Miller, Robert J., Dhal, Pradeep K.

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Long-Range Guanine Oxidation in DNA Restriction Fragments by a Triplex-Directed Naphthalene Diimide Intercalator von Núñez, Megan E, Noyes, Katherine T, Gianolio, Diego A, McLaughlin, Larry W, Barton, Jacqueline K

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Well-Defined Aminooxy Terminated N‑(2-Hydroxypropyl) Methacrylamide Macromers for Site Specific Bioconjugation of Glycoproteins von Dhal, Pradeep K, Polomoscanik, Steven C, Gianolio, Diego A, Starremans, Patrick G, Busch, Michelle, Alving, Kim, Chen, Bo, Miller, Robert J

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Oxidative Repair of a Thymine Dimer in DNA from a Distance by a Covalently Linked Organic Intercalator von Vicic, David A, Odom, Duncan T, Núñez, Megan E, Gianolio, Diego A, McLaughlin, Larry W, Barton, Jacqueline K

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Targeting HER2-positive cancer with dolastatin 15 derivatives conjugated to trastuzumab, novel antibody–drug conjugates von Gianolio, Diego A., Rouleau, Cecile, Bauta, William E., Lovett, Dennis, Cantrell, William R., Recio, Antonio, Wolstenholme-Hogg, Paul, Busch, Michelle, Pan, Peng, Stefano, James E., Kramer, Hildegard M., Goebel, James, Krumbholz, Roy D., Roth, Stephanie, Schmid, Steven M., Teicher, Beverly A.

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Correction to Well-Defined Aminooxy Terminated N‑(2-Hydroxypropyl) Methacrylamide Macromers for Site Specific Bioconjugation of Glycoproteins von Dhal, Pradeep K, Polomoscanik, Steven C, Gianolio, Diego A, Starremans, Patrick G, Busch, Michelle, Alving, Kim, Chen, Bo, Miller, Robert J

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Hyaluronan-Tethered Opioid Depots: Synthetic Strategies and Release Kinetics In Vitro and In Vivo von Gianolio, Diego A, Philbrook, Michael, Avila, Luis Z, Young, Lauren E, Plate, Lars, Santos, Michael R, Bernasconi, Richard, Liu, Hanlan, Ahn, Sujin, Sun, Wei, Jarrett, Peter K, Miller, Robert J

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Synthesis and Evaluation of Hydrolyzable Hyaluronan-Tethered Bupivacaine Delivery Systems von Gianolio, Diego A, Philbrook, Michael, Avila, Luis Z, MacGregor, Hollace, Duan, Su X, Bernasconi, Richard, Slavsky, Marina, Dethlefsen, Sandra, Jarrett, Peter K, Miller, Robert J

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Phase I study of the mutant IDH1 inhibitor ivosidenib: Long-term safety and clinical activity in patients with conventional chondrosarcoma von Tap, William D., Cote, Gregory Michael, Burris, Howard A., Gore, Lia, Beeram, Muralidhar, Conley, Anthony Paul, Gianolio, Diego A., Qu, Zhe, Gliser, Camelia, Pandya, Shuchi Sumant, Trent, Jonathan C.

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Updated efficacy and safety data from the AGILE study in patients with newly diagnosed acute myeloid leukemia treated with ivosidenib + azacitidine compared to placebo + azacitidin... von De Botton, Stéphane, Montesinos, Pau, Vives Polo, Susana, Zarzycka, Ewa, Wang, Jianxiang, Riva, Marta, Heuser, Michael, Calado, Rodrigo T., Schuh, Andre C., Yeh, Su-Peng, Hui, Jianan, Gianolio, Diego A., Patel, Prapti Arvind, Recher, Christian, Dohner, Hartmut

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Changes in health-related quality of life in patients with newly diagnosed acute myeloid leukemia receiving ivosidenib + azacitidine or placebo + azacitidine von Schuh, Andre C., De Botton, Stéphane, Recher, Christian, Vives Polo, Susana, Zarzycka, Ewa, Wang, Jianxiang, Bertani, Giambattista, Heuser, Michael, Calado, Rodrigo T., Yeh, Su-Peng, Hui, Jianan, Pandya, Shuchi Sumant, Gianolio, Diego A., Chamberlain, Christina X., Dohner, Hartmut, Montesinos, Pau

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AGILE: A Global, Randomized, Double-Blind, Phase 3 Study of Ivosidenib + Azacitidine Versus Placebo + Azacitidine in Patients with Newly Diagnosed Acute Myeloid Leukemia with an ID... von Montesinos, Pau, Recher, Christian, Vives, Susana, Zarzycka, Ewa, Wang, Jianxiang, Bertani, Giambattista, Heuser, Michael, Calado, Rodrigo T., Schuh, Andre C., Yeh, Su-Peng, Daigle, Scott R., Hui, Jianan, Zhang, Vickie, Pandya, Shuchi S., Gianolio, Diego A., de Botton, Stephane, Döhner, Hartmut

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Tethered naphthalene diimide intercalators enhance DNA triplex stability von Gianolio, Diego A., McLaughlin, Larry W.

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