Effective delivery of Complex Innovative Design (CID) cancer trials—A consensus statement von Blagden, Sarah P., Billingham, Lucinda, Brown, Louise C., Buckland, Sean W., Cooper, Alison M., Ellis, Stephanie, Fisher, Wendy, Hughes, Helen, Keatley, Debbie A., Maignen, Francois M., Morozov, Alex, Navaie, Will, Pearson, Sarah, Shaaban, Abeer, Wydenbach, Kirsty, Kearns, Pamela R.

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Continuous murmur--the auscultatory expression of a variety of pathological conditions von Ginghină, C, Năstase, O A, Ghiorghiu, I, Egher, L

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Management and ethics issues in rehabilitation and balneoclimatology von Nica, AS, Ghiorghiu, I, Constantinovici, M, Miclaus, RS, Mitoiu, BI

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Severe pulmonary arterial hypertension associated with congenital cardiac shunts: evolution under specific treatment von Negoi, R I, Ghiorghiu, I, Filipoiu, F, Hostiuc, M, Negoi, I, Ginghina, C

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Poster Session Saturday 14 December - AM: 14/12/2013, 08:30-12:30 Location: Poster area von Muraru, D., Addetia, K., Veronesi, F., Corsi, C., Mor-Avi, V., Yamat, M., Weinert, L., Lang, R., Badano, L., Faita, F., Di Lascio, N., Bruno, R., Bianchini, E., Ghiadoni, L., Sicari, R., Gemignani, V., Angelis, A., Ageli, K., Ioakimidis, N., Chrysohoou, C., Agelakas, A., Felekos, I., Vaina, S., Aznaourides, K., Vlachopoulos, C., Stefanadis, C., Nemes, A., Szolnoky, G., Gavaller, H., Gonczy, A., Kemeny, L., Forster, T., Ramalho, A., Placido, R., Marta, L., Menezes, M., Magalhaes, A., Cortez Dias, N., Martins, S., Almeida, A., Pinto, F., Nunes Diogo, A., Botezatu, C.-D., Enache, R., Popescu, B., Nastase, O., Coman, M., Ghiorghiu, I., Calin, A., Rosca, M., Beladan, C., Ginghina, C., Grapsa, J., Cabrita, I., Durighel, G., O'regan, D., Dawson, D., Nihoyannopoulos, P., Pellicori, P., Kallvikbacka-Bennett, A., Zhang, J., Lukaschuk, E., Joseph, A., Bourantas, C., Loh, H., Bragadeesh, T., Clark, A., Cleland, J., Lomax, S., Putzu, P., Diercx, R., Parsons, S., Dicken, B., Vered, Z., Adirevitz, L., Dragu, R., Blatt, A., Karev, E., Malca, Y., Roytvarf, A., Marek, D., Sovova, E., Berkova, M., Cihalik, C., Taborsky, M., Lindqvist, P., Tossavainen, E., Soderberg, S., Gonzales, M., Gustavsson, S., Henein, M., Sonne, C., Bott-Fluegel, L., Hauck, S., Lesevic, H., Hadamitzky, M., Wolf, P., Kolb, C., Bandera, F., Pellegrino, M.

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Echocardiography in congenital mitral valve regurgitation--the liaison between cardiologist and surgeon von Ginghină, Carmen, Vlădaia, Aurora, Ghiorghiu, Ioana, Serban, Marinela, Popescu, B A, Jurcuţ, Ruxandra

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Clinical Cases: See that case at least once1174An unrecognized mechanism of functional tricuspid regurgitation revealed by transthoracic three-dimensional echocardiography1175Left... von Bidviene, J., Zhukovskiy, N., Peritore, A., Rodrigues, I., Tundidor Sanz, ME, Guerreiro, RA, Marini, C., Cereda, A., Dorobantu, DM, Cavalli, G., Cavaliere, A., Genovese, D., Romeo, G., Aruta, P., Cucchini, U., Iliceto, S., Badano, LP, Muraru, D., Okhotin, A., Privorotskaya, V., De Chiara, B., Musca, F., Spano', F., Santambrogio, G., Casadei, F., Forti, E., Mutignani, M., Giannattasio, C., Moreo, A., Galrinho, A., Branco, L., Bravio, I., Machado, D., Monteiro, A., Daniel, P., Ferreira, L., Carvalho, R., Ferreira, R., Tierra Rodriguez, AM, Dios Diez, P., Mayorga Bajo, A., Fernandez Gomez, MJ, Dominguez Calvo, JI, Rogriguez Palomo, D., Hernandez Rodriguez, J., Congo, K., Carvalho, J., Pais, J., Bras, D., Picarra, B., Caeiro, A., Fragata, J., Aguiar, J., Stella, S., Rosa, I., Pavon, AG, Ancona, F., Margonato, A., Colombo, A., Latib, A., Montorfano, M., Agricola, E., Ghiorghiu, IA, Popescu, BA, Coman, IM, Ginghina, CD, Enache, R.

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THE PREVALENCE OF HYPERTENSION AND OF LEFT VENTRICULAR HYPERTROPHY IN A ROMANIAN POPULATION. A CLINICAL-ECHOCARDIOGRAPHIC STUDY: P3.45 von Ginghina, C., Popescu, B. A., Serban, M., Ghiorghiu, I., Parlea, M., Siminiceanu, C., Matei, C., Kulcsar, I., Apetrei, E.

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Spontaneous echo contrast of unexpected etiology von Serban, Marinela, Ghiorghiu, Ioana, Craciunescu, Ileana, Calin, Cosmin, Platon, Pavel, Apetrei, Eduard, Ginghina, Carmen

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723 Deep venous thrombosis in children-etiological and diagnosis particularities von GHIORGHIU, I, IANCU, M, STOICA, A, ARSENESCU, I, DUMITRU, M, SERBAN, M, USCATESCU, V, GINGHINA, C

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503 Detection of significant coronary artery stenosis by resting wall motion abnormalities, in patients with suspected coronary artery disease von CRACIUNESCU, I, SERBAN, M, VASILE, S, DELEANU, D, GHIORGHIU, I, MIHAESCU, C, ARONNICULESCU, I, GINGHINA, C

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1158 Noninvasive diagnosis of biopsy-proven cardiac amyloidosis von GINGHINA, C, CRACIUNESCU, I, POPESCU, B, SERBAN, M, POPA, A, ARSENESCU, I, GHIORGHIU, I, DELEANU, D

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512 Prevalence of hypertension and left ventricular hypertrophy in a Romanian population. A populational clinical — echocardiographic study von GINGHINA, C, POPESCU, B, SERBAN, M, GHIORGHIU, I, PARLEA, M, MATEI, C, KULCSAR, I, APETREI, E

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317 The profile of cardiac failure in restrictive cardiomyopathy: an interpretation based on the site of restriction von GINGHINA, C, POPESCU, B, STOIAN, I, GHIORGHIU, I, SERBAN, M, IONASCU, R, ARSENESCU, I, POPA, A, APETREI, E

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557 Echocardiographic exam accuracy in evaluation of cardiac findings spectrum in Marfan syndrome von GINGHINA, C, STOIAN, I, POPESCU, B, SERBAN, M, ARSENESCU, I, POPA, A, GHIORGHIU, I, IONASCU, R, COMAN, I, APETREI, E

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Osimertinib or Platinum–Pemetrexed in EGFR T790M–Positive Lung Cancer von Mok, Tony S, Wu, Yi-Long, Ahn, Myung-Ju, Garassino, Marina C, Kim, Hye R, Ramalingam, Suresh S, Shepherd, Frances A, He, Yong, Akamatsu, Hiroaki, Theelen, Willemijn S.M.E, Lee, Chee K, Sebastian, Martin, Templeton, Alison, Mann, Helen, Marotti, Marcelo, Ghiorghiu, Serban, Papadimitrakopoulou, Vassiliki A

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AZD9291 in EGFR Inhibitor–Resistant Non–Small-Cell Lung Cancer von Jänne, Pasi A, Yang, James Chih-Hsin, Kim, Dong-Wan, Planchard, David, Ohe, Yuichiro, Ramalingam, Suresh S, Ahn, Myung-Ju, Kim, Sang-We, Su, Wu-Chou, Horn, Leora, Haggstrom, Daniel, Felip, Enriqueta, Kim, Joo-Hang, Frewer, Paul, Cantarini, Mireille, Brown, Kathryn H, Dickinson, Paul A, Ghiorghiu, Serban, Ranson, Malcolm

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Osimertinib for pretreated EGFR Thr790Met-positive advanced non-small-cell lung cancer (AURA2): a multicentre, open-label, single-arm, phase 2 study von Goss, Glenwood, Dr Prof, Tsai, Chun-Ming, Prof, Shepherd, Frances A, Prof, Bazhenova, Lyudmila, Prof, Lee, Jong Seok, MD, Chang, Gee-Chen, MD, Crino, Lucio, MD, Satouchi, Miyako, MD, Chu, Quincy, MD, Hida, Toyoaki, MD, Han, Ji-Youn, Prof, Juan, Oscar, MD, Dunphy, Frank, Prof, Nishio, Makoto, MD, Kang, Jin-Hyoung, MD, Majem, Margarita, MD, Mann, Helen, MSc, Cantarini, Mireille, MD, Ghiorghiu, Serban, MD, Mitsudomi, Tetsuya, Prof

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TATTON: a multi-arm, phase Ib trial of osimertinib combined with selumetinib, savolitinib, or durvalumab in EGFR-mutant lung cancer von Oxnard, G.R., Yang, J.C.-H., Yu, H., Kim, S.-W., Saka, H., Horn, L., Goto, K., Ohe, Y., Mann, H., Thress, K.S., Frigault, M.M., Vishwanathan, K., Ghiorghiu, D., Ramalingam, S.S., Ahn, M.-J.

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Osimertinib As First-Line Treatment of EGFR Mutation-Positive Advanced Non-Small-Cell Lung Cancer von Ramalingam, Suresh S, Yang, James C-H, Lee, Chee Khoon, Kurata, Takayasu, Kim, Dong-Wan, John, Thomas, Nogami, Naoyuki, Ohe, Yuichiro, Mann, Helen, Rukazenkov, Yuri, Ghiorghiu, Serban, Stetson, Daniel, Markovets, Aleksandra, Barrett, J Carl, Thress, Kenneth S, Jänne, Pasi A

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