Fibrinolysis greater than 3% is the critical value for initiation of antifibrinolytic therapy von Chapman, Michael P, Moore, Ernest E, Ramos, Christopher R, Ghasabyan, Arsen, Harr, Jeffrey N, Chin, Theresa L, Stringham, John R, Sauaia, Angela, Silliman, Christopher C, Banerjee, Anirban

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Exploring ethical conflicts in emergency trauma research: The COMBAT (Control of Major Bleeding after Trauma) study experience von Chin, Theresa L., MD, Moore, Ernest E., MD, Coors, Marilyn E., PhD, Chandler, James G., MD, Ghasabyan, Arsen, MPH, Harr, Jeffrey N., MD, MPH, Stringham, John R., MD, Ramos, Christopher R., MD, Ammons, Sarah, BS, Banerjee, Anirban, PhD, Sauaia, Angela, MD, PhD

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Plasma-first resuscitation to treat haemorrhagic shock during emergency ground transportation in an urban area: a randomised trial von Moore, Hunter B, Moore, Ernest E, Chapman, Michael P, McVaney, Kevin, Bryskiewicz, Gary, Blechar, Robert, Chin, Theresa, Burlew, Clay Cothren, Pieracci, Fredric, West, F Bernadette, Fleming, Courtney D, Ghasabyan, Arsen, Chandler, James, Silliman, Christopher C, Banerjee, Anirban, Sauaia, Angela

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Goal-directed Hemostatic Resuscitation of Trauma-induced Coagulopathy: A Pragmatic Randomized Clinical Trial Comparing a Viscoelastic Assay to Conventional Coagulation Assays von Gonzalez, Eduardo, Moore, Ernest E, Moore, Hunter B, Chapman, Michael P, Chin, Theresa L, Ghasabyan, Arsen, Wohlauer, Max V, Barnett, Carlton C, Bensard, Denis D, Biffl, Walter L, Burlew, Clay C, Johnson, Jeffrey L, Pieracci, Fredric M, Jurkovich, Gregory J, Banerjee, Anirban, Silliman, Christopher C, Sauaia, Angela

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Association of Prehospital Plasma Transfusion With Survival in Trauma Patients With Hemorrhagic Shock When Transport Times Are Longer Than 20 Minutes: A Post Hoc Analysis of the PA... von Pusateri, Anthony E, Moore, Ernest E, Moore, Hunter B, Le, Tuan D, Guyette, Francis X, Chapman, Michael P, Sauaia, Angela, Ghasabyan, Arsen, Chandler, James, McVaney, Kevin, Brown, Joshua B, Daley, Brian J, Miller, Richard S, Harbrecht, Brian G, Claridge, Jeffrey A, Phelan, Herb A, Witham, William R, Putnam, A. Tyler, Sperry, Jason L

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Overwhelming tPA release, not PAI-1 degradation, is responsible for hyperfibrinolysis in severely injured trauma patients von Chapman, Michael P, Moore, Ernest E, Moore, Hunter B, Gonzalez, Eduardo, Gamboni, Fabia, Chandler, James G, Mitra, Sanchayita, Ghasabyan, Arsen, Chin, Theresa L, Sauaia, Angela, Banerjee, Anirban, Silliman, Christopher C

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Fibrinolysis shutdown is associated with a fivefold increase in mortality in trauma patients lacking hypersensitivity to tissue plasminogen activator von Moore, Hunter B, Moore, Ernest E, Huebner, Benjamin R, Dzieciatkowska, Monika, Stettler, Gregory R, Nunns, Geoffrey R, Lawson, Peter J, Ghasabyan, Arsen, Chandler, James, Banerjee, Anirban, Silliman, Christopher, Sauaia, Angela, Hansen, Kirk C

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Plasma succinate is a predictor of mortality in critically injured patients von DʼAlessandro, Angelo, Moore, Hunter B, Moore, Ernest E, Reisz, Julie A, Wither, Matthew J, Ghasasbyan, Arsen, Chandler, James, Silliman, Christopher C, Hansen, Kirk C, Banerjee, Anirban

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Functional fibrinogen assay indicates that fibrinogen is critical in correcting abnormal clot strength following trauma von Harr, Jeffrey N, Moore, Ernest E, Ghasabyan, Arsen, Chin, Theresa L, Sauaia, Angela, Banerjee, Anirban, Silliman, Christopher C

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Study of Alteplase for Respiratory Failure in SARS-CoV-2 COVID-19: A Vanguard Multicenter, Rapidly Adaptive, Pragmatic, Randomized Controlled Trial von Barrett, Christopher D, Moore, Hunter B, Moore, Ernest E, Wang, Janice, Hajizadeh, Negin, Biffl, Walter L, Lottenberg, Lawrence, Patel, Purvesh R, Truitt, Michael S, McIntyre, Jr, Robert C, Bull, Todd M, Ammons, Lee Anne, Ghasabyan, Arsen, Chandler, James, Douglas, Ivor S, Schmidt, Eric P, Moore, Peter K, Wright, Franklin L, Ramdeo, Ramona, Borrego, Robert, Rueda, Mario, Dhupa, Achal, McCaul, D Scott, Dandan, Tala, Sarkar, Pralay K, Khan, Benazir, Sreevidya, Coimbatore, McDaniel, Conner, Grossman Verner, Heather M, Pearcy, Christopher, Anez-Bustillos, Lorenzo, Baedorf-Kassis, Elias N, Jhunjhunwala, Rashi, Shaefi, Shahzad, Capers, Krystal, Banner-Goodspeed, Valerie, Talmor, Daniel S, Sauaia, Angela, Yaffe, Michael B

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Succinate Activation of SUCNR1 Predisposes Severely Injured Patients to Neutrophil-mediated ARDS von Nunns, Geoffrey R., Vigneshwar, Navin, Kelher, Marguerite R., Stettler, Gregory R., Gera, Lajos, Reisz, Julie A., D’Alessandro, Angelo, Ryon, Joshua, Hansen, Kirk C., Gamboni, Fabia, Moore, Ernest E., Peltz, Erik D., Cohen, Mitchell J., Jones, Kenneth L., Sauaia, Angela, Liang, Xiayuan, Banerjee, Anirban, Ghasabyan, Arsen, Chandler, James G., Rodawig, Sophia, Jones, Carter, Eitel, Andrew, Hom, Patrick, Silliman, Christopher C.

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Platelets are dominant contributors to hypercoagulability after injury von Harr, Jeffrey N, Moore, Ernest E, Chin, Theresa L, Ghasabyan, Arsen, Gonzalez, Eduardo, Wohlauer, Max V, Banerjee, Anirban, Silliman, Christopher C, Sauaia, Angela

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Rapid TEG efficiently guides hemostatic resuscitation in trauma patients von Coleman, Julia R, Moore, Ernest E, Chapman, Michael P, Banerjee, Anirban, Silliman, Christopher C, Ghasabyan, Arsen, Chandler, James, Samuels, Jason M, Sauaia, Angela

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Zone 1 REBOA in a combat DCBI swine model does not worsen brain injury von Cralley, Alexis L., Moore, Ernest E., Fox, Charles J., Kissau, Daniel, DeBot, Margo, Schaid, Terry R., Mitra, Sanchayita, Hom, Patrick, Fragoso, Miguel, Ghasabyan, Arsen, Erickson, Christopher, D’Alessandro, Angelo, Hansen, Kirk C., Cohen, Mitchell J., Silliman, Christopher C., Sauaia, Angela

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A role for decorin in improving motor deficits after traumatic brain injury von Oshima, Kaori, Siddiqui, Noah, Orfila, James E., Carter, Danelle, Laing, Justin, Han, Xiaorui, Zakharevich, Igor, Iozzo, Renato V, Ghasabyan, Arsen, Moore, Hunter, Zhang, Fuming, Linhardt, Robert J, Moore, Ernest E, Quillinan, Nidia, Schmidt, Eric P, Herson, Paco S, Hippensteel, Joseph A

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Untangling Sex Dimorphisms in Coagulation: Initial Steps Toward Precision Medicine for Trauma Resuscitation von Coleman, Julia R., Moore, Ernest E., Sauaia, Angela, Samuels, Jason M., Moore, Hunter B., Ghasabyan, Arsen, Chandler, James G., Swope, Megan L., Fleming, Courtney D., Banerjee, Anirban, Cohen, Mitchell J., Silliman, Christopher C., Peltz, Erik D., Chapman, Michael P.

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Empiric transfusion strategies during life-threatening hemorrhage von Nunns, Geoffrey R., Moore, Ernest E., Stettler, Gregory R., Moore, Hunter B., Ghasabyan, Arsen, Cohen, Mitchell, Huebner, Benjamin R., Silliman, Christopher C., Banerjee, Anirban, Sauaia, Angela

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The "Death Diamond": Rapid thrombelastography identifies lethal hyperfibrinolysis von Chapman, Michael P, Moore, Ernest E, Moore, Hunter B, Gonzalez, Eduardo, Morton, Alexander P, Chandler, James, Fleming, Courtney D, Ghasabyan, Arsen, Silliman, Christopher C, Banerjee, Anirban, Sauaia, Angela

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All animals are equal but some animals are more equal than others: Plasma lactate and succinate in hemorrhagic shock-A comparison in rodents, swine, nonhuman primates, and injured... von Reisz, Julie A, Wither, Matthew J, Moore, Ernest E, Slaughter, Anne L, Moore, Hunter B, Ghasabyan, Arsen, Chandler, James, Schaub, Leasha J, Fragoso, Miguel, Nunns, Geoffrey, Silliman, Christopher C, Hansen, Kirk C, Banerjee, Anirban, Sheppard, Forest R, D'Alessandro, Angelo

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Platelet adenosine diphosphate receptor inhibition provides no advantage in predicting need for platelet transfusion or massive transfusion von Stettler, Gregory R., Moore, Ernest E., Moore, Hunter B., Nunns, Geoffrey R., Huebner, Benjamin R., Einersen, Peter, Ghasabyan, Arsen, Silliman, Christopher C., Banerjee, Anirban, Sauaia, Angela

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