Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study von Copson, Ellen R, Maishman, Tom C, Tapper, Will J, Cutress, Ramsey I, Greville-Heygate, Stephanie, Altman, Douglas G, Eccles, Bryony, Gerty, Sue, Durcan, Lorraine T, Jones, Louise, Evans, D Gareth, Thompson, Alastair M, Pharoah, Paul, Easton, Douglas F, Dunning, Alison M, Hanby, Andrew, Lakhani, Sunil, Eeles, Ros, Gilbert, Fiona J, Hamed, Hisham, Hodgson, Shirley, Simmonds, Peter, Stanton, Louise, Eccles, Diana M

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Germline variation in ADAMTSL1 is associated with prognosis following breast cancer treatment in young women von Kadalayil, Latha, Khan, Sofia, Nevanlinna, Heli, Fasching, Peter A., Couch, Fergus J., Hopper, John L., Liu, Jianjun, Maishman, Tom, Durcan, Lorraine, Gerty, Sue, Blomqvist, Carl, Rack, Brigitte, Janni, Wolfgang, Collins, Andrew, Eccles, Diana, Tapper, William

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Identification of Inherited Genetic Variations Influencing Prognosis in Early-Onset Breast Cancer von RAFIQ, Sajjad, TAPPER, William, ECCLES, Diana, COLLINS, Andrew, KHAN, Sofia, POLITOPOULOS, Loannis, GERTY, Sue, BLOMQVIST, Carl, COUCH, Fergus J, NEVANLINNA, Heli, JIANJUN LIU

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The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer von Tapper, William, Hammond, Victoria, Gerty, Sue, Ennis, Sarah, Simmonds, Peter, Collins, Andrew, Eccles, Diana

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Prospective study of Outcomes in Sporadic versus Hereditary breast cancer (POSH): study protocol von Eccles, Diana, Gerty, Sue, Simmonds, Peter, Hammond, Victoria, Ennis, Sarah, Altman, Douglas G

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Local Recurrence and Breast Oncological Surgery in Young Women With Breast Cancer: The POSH Observational Cohort Study von Maishman, Tom, Cutress, Ramsey I, Hernandez, Aurea, Gerty, Sue, Copson, Ellen R, Durcan, Lorraine, Eccles, Diana M

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Prospective Observational Study of Breast Cancer Treatment Outcomes for UK Women Aged 18―40 Years at Diagnosis: The POSH Study von COPSON, Ellen, ECCLES, Bryony, JONES, Louise, BLISS, Judith, ECCLES, Diana, MAISHMAN, Tom, GERTY, Sue, STANTON, Louise, CUTRESS, Ramsey I, ALTMAN, Douglas G, DURCAN, Lorraine, SIMMONDS, Peter, LAWRENCE, Gill

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Information requirements of young women with breast cancer treated with mastectomy or breast conserving surgery: A systematic review von Recio-Saucedo, Alejandra, Gerty, Sue, Foster, Claire, Eccles, Diana, Cutress, Ramsey I

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Associations of Breast Cancer Risk Factors With Tumor Subtypes: A Pooled Analysis From the Breast Cancer Association Consortium Studies von YANG, Xiaohong R, CHANG-CLAUDE, Jenny, FASCHING, Peter A, HEIN, Rebecca, SPURDLE, Amanda B, BLOWS, Fiona, DRIVER, Kristy, FLESCH-JANYS, Dieter, HEINZ, Judith, SINN, Peter, VRIELING, Alina, HEIKKINEN, Tuomas, GOODE, Ellen L, AITTOMÄKI, Kristiina, HEIKKILÄ, Paivi, BLOMQVIST, Carl, LISSOWSKA, Jolanta, PEPLONSKA, Beata, CHANOCK, Stephen, FIGUEROA, Jonine, BRINTON, Louise, HALL, Per, CZENE, Kamila, COUCH, Fergus J, HUMPHREYS, Keith, DARABI, Hatef, JIANJUN LIU, VAN 'T VEER, Laura J, VAN LEEUWEN, Flora E, ANDRULIS, Irene L, GLENDON, Gord, KNIGHT, Julia A, MULLIGAN, Anna Marie, O'MALLEY, Frances P, NEVANLINNA, Heli, WEERASOORIYA, Nayana, JOHN, Esther M, BECKMANN, Matthias W, HARTMANN, Arndt, WEIHBRECHT, Sebastian B, WACHTER, David L, JUD, Sebastian M, LOEHBERG, Christian R, BAGLIETTO, Laura, ENGLISH, Dallas R, MILNE, Roger L, GILES, Graham G, MCLEAN, Catriona A, SEVERI, Gianluca, LAMBRECHTS, Diether, VANDORPE, Thijs, WELTENS, Caroline, PARIDAENS, Robert, SMEETS, Ann, NEVEN, Patrick, GAUDET, Mia, SCHMIDT, Marjanka K, BROEKS, Annegien, COX, Angela

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A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population von Healey, Sue, Loud, Jennifer T, dos Santos Silva, Isabel, Hakonarson, Hakon, Garber, Judy, Blank, Stephanie V, Huzarski, Tomasz, Godwin, Andrew K, Spurdle, Amanda B, Soucy, Penny, Izatt, Louise, Southey, Melissa, Blum, Joanne L, Cox, Angela, Buys, Saundra S, Fasching, Peter A, Laitman, Yael, Rantala, Johanna, Peto, Julian, Montagna, Marco, Flesch-Janys, Dieter, Offit, Kenneth, Peock, Susan, Manoukian, Siranoush, Neuhausen, Susan L, Weitzel, Jeffrey, Wappenschmidt, Barbara, Sutter, Christian, Osorio, Ana, Rookus, Matti A, Terry, Mary-Beth, Friedman, Eitan, Ghoussaini, Maya, Martin, Nicholas G, Giraud, Sophie, Devilee, Peter, Gayther, Simon A, Engel, Christoph, Tung, Nadine, Singer, Christian F, Simard, Jacques, Byrski, Tomasz, Peterlongo, Paolo, Cook, Margaret, Bonanni, Bernardo, Goldgar, David E, Frost, Debra, Easton, Douglas F, Hoogerbrugge, Nicoline, Meindl, Alfons, Diasio, Robert B, Sinilnikova, Olga M, Kartsonaki, Christiana, Antoniou, Antonis C, Stoppa-Lyonnet, Dominique, Rodriguez, Gustavo C, Nathanson, Katherine L, Gaudet, Mia M, Cross, Simon S, Cybulski, Cezary, Winqvist, Robert, Fountzilas, George, van den Ouweland, Ans, Hansen, Thomas V O, Beattie, Mary S, Nielsen, Finn C, Douglas, Fiona, Caldes, Trinidad, Hopper, John L, Hogervorst, Frans B L, Oliver, Clare, Gerty, Sue M, Yannoukakos, Drakoulis, Lambrechts, Diether, Caron, Olivier, Lee, Adam M, Hardouin, Agnès, Vachon, Celine, Chenevix-Trench, Georgia, Holland, Helene, Blanco, Ignacio, Beckmann, Matthias W, Paridaens, Robert, Barrowdale, Daniel, Piedmonte, Marion, Couch, Fergus J, Lasset, Christine, Górski, Bohdan, Domchek, Susan M, Loman, Niklas, Nevanlinna, Heli, Rebbeck, Timothy, Thomassen, Mads, Narod, Stephen, Eccles, Diana, Benitez, Javier, Arason, Adalgeir, Basil, Jack, Lazaro, Conxi, Phelan, Catherine

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Local recurrence in young women with invasive breast cancer: The POSH study von Maishman, Tom, Cutress, Ramsey, Hernandez, Aurea, Gerty, Sue, Copson, Ellen, Durcan, Lorraine, Eccles, Diana

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19. A review of PREDICT using the POSH cohort (women aged 40 years or younger at breast cancer diagnosis) von Maishman, Tom, Wishart, Gordon, Copson, Ellen, Stanton, Louise, Gerty, Sue, Dicks, Ed, Durcan, Lorraine, Pharoah, Paul, Eccles, Diana

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Breast oncological surgery and local recurrence in a Prospective study of Outcome of Sporadic versus Hereditary breast cancer (POSH) von Gerty, Sue, Cutress, Ramsey, Copson, Ellen, Simmonds, Peter, Eccles, Diana

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Abstract 2671: CYP2D6 polymorphisms are not associated with tamoxifen outcome in premenopausal women with ER positive breast cancer of the POSH cohort von Saladores, Pilar H., Schroth, Werner, Eccles, Diana, Tapper, William, Gerty, Sue, Brauch, Hiltrud B.

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A review of the online prognositc model predict using the POSH cohort (women aged ≤40 years at breast cancer diagnosis) von Maishman, Tom, Copson, Ellen, Stanton, Louise, Gerty, Sue, Dicks, Ed, Durcan, Lorraine, Wishart, Gordon, Pharoah, Paul, Eccles, Diana

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Information required for surgical decision making in young women with breast cancer von Recio-Saucedo, Alejandra, Gerty, Sue, Foster, Claire, Cutress, Ramsey, Eccles, Diana

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Breast oncological surgical treatment in 2409 young women recruited to a Prospective study of Outcome of Sporadic versus Hereditary breast cancer (POSH) von Gerty, Sue, Cutress, R, Simmonds, P, Eccles, D

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Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the breast cancer association consortium studies von Yang, Xiaohong R, Goode, Ellen L, Milne, Roger L, Gaudet, Mia, Schmidt, Marjanka K, Fasching, Peter A, Hein, Rebecca, Driver, Kristy, Flesch-Janys, Dieter, Sinn, Peter, Heikkinen, Tuomas, Aittomäki, Kristiina, Blomqvist, Carl, Peplonska, Beata, Chanock, Stephen, Figueroa, Jonine, Brinton, Louise, Czene, Kamila, Humphreys, Keith, Darabi, Hatef, Liu, Jianjun, Van ‘t Veer, Laura J, van Leeuwen, Flora E, Glendon, Gord, Mulligan, Anna Marie, O’Malley, Frances P, John, Esther M, Loehberg, Christian R, Baglietto, Laura, English, Dallas R, Giles, Graham G, McLean, Catriona A, Lambrechts, Diether, Vandorpe, Thijs, Paridaens, Robert, Smeets, Ann, Wang, Xianshu, Olson, Janet E, Cafourek, Victoria, Kosel, Matthew, Balasubramanian, Sabapathy P, Reed, Malcolm W. R, Meyer, Andreas, Ay, Aysun, Hillemanns, Peter, Arias Pérez, Jose Ignacio, Rodríguez, Primitiva Menéndez, Ko, Yon-Dschun, Fischer, Hans-Peter, Brüning, Thomas, Brauch, Hiltrud, Gerty, Sue M, Tomlinson, Ian P, Miller, Nicola, McInerney, Niall, Anton-Culver, Hoda, Ziogas, Argyrios, Shen, Chen-Yang, Wu, Pei-Ei, Hsu, Giu-Cheng, Haiman, Christopher A, Henderson, Brian E, Le Marchand, Loic, Kolonel, Laurence N, Lindblom, Annika, Jakubowska, Anna, Huzarski, Tomasz, Byrski, Tomasz, Górski, Bohdan, Hooning, Maartje J, Hollestelle, Antoinette, Kriege, Mieke, Tilanus-Linthorst, Madeleine M. A, Pylkäs, Katri, Jukkola-Vuorinen, Arja, Hirvikoski, Pasi, Mannermaa, Arto, Kosma, Veli-Matti, Auvinen, Päivi, Sironen, Reijo, Bojesen, Stig E, Dynnes Ørsted, David, Chenevix-Trench, Georgia, Manoukian, Siranoush, Barile, Monica, Hunter, David J, Brennan, Paul, McKay, James, Huijts, P.E.A, Tollenaar, RAEM, Seynaeve, C, Hopper, John L, Hammet, Fleur, Smith, Letitia D, Southey, Melissa C, Humphreys, Manjeet K, Easton, Douglas, Pharoah, Paul, Sherman, Mark E, Garcia-Closas, Montserrat

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Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study von Copson, Ellen R, Maishman, Tom C, Tapper, Will J, Cutress, Ramsey I, Greville-Heygate, Stephanie, Altman, Douglas G, Eccles, Bryony, Gerty, Sue, Durcan, Lorraine T, Jones, Louise, Evans, D Gareth, Thompson, Alastair M, Pharoah, Paul, Easton, Douglas F, Dunning, Alison M, Hanby, Andrew, Lakhani, Sunil, Eeles, Ros, Gilbert, Fiona J, Hamed, Hisham, Hodgson, Shirley, Simmonds, Peter, Stanton, Louise, Eccles, Diana M

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Germline BRCA mutation and outcome in young-onset breast cancer (POSH): a prospective cohort study von Copson, Ellen R, Maishman, Tom C, Tapper, Will J, Cutress, Ramsey I, Greville-Heygate, Stephanie, Altman, Douglas G, Eccles, Bryony, Gerty, Sue, Durcan, Lorraine T, Jones, Louise, Evans, D Gareth, Thompson, Alastair M, Pharoah, Paul, Easton, Douglas F, Dunning, Alison M, Hanby, Andrew, Lakhani, Sunil, Eeles, Ros, Gilbert, Fiona J, Hamed, Hisham, Hodgson, Shirley, Simmonds, Peter, Stanton, Louise, Eccles, Diana M

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