Targeted gene correction of human hematopoietic stem cells for the treatment of Wiskott - Aldrich Syndrome von Rai, Rajeev, Romito, Marianna, Rivers, Elizabeth, Turchiano, Giandomenico, Blattner, Georges, Vetharoy, Winston, Ladon, Dariusz, Andrieux, Geoffroy, Zhang, Fang, Zinicola, Marta, Leon-Rico, Diego, Santilli, Giorgia, Thrasher, Adrian J., Cavazza, Alessia

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Spatially confined sub-tumor microenvironments in pancreatic cancer von Grünwald, Barbara T., Devisme, Antoine, Andrieux, Geoffroy, Vyas, Foram, Aliar, Kazeera, McCloskey, Curtis W., Macklin, Andrew, Jang, Gun Ho, Denroche, Robert, Romero, Joan Miguel, Bavi, Prashant, Bronsert, Peter, Notta, Faiyaz, O’Kane, Grainne, Wilson, Julie, Knox, Jennifer, Tamblyn, Laura, Udaskin, Molly, Radulovich, Nikolina, Fischer, Sandra E., Boerries, Melanie, Gallinger, Steven, Kislinger, Thomas, Khokha, Rama

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BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation von Reischmann, Nadine, Andrieux, Geoffroy, Griffin, Ricarda, Reinheckel, Thomas, Boerries, Melanie, Brummer, Tilman

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Gab2 deficiency prevents Flt3-ITD driven acute myeloid leukemia in vivo von Spohr, Corinna, Poggio, Teresa, Andrieux, Geoffroy, Schönberger, Katharina, Cabezas-Wallscheid, Nina, Boerries, Melanie, Halbach, Sebastian, Illert, Anna L., Brummer, Tilman

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Bile acids regulate intestinal antigen presentation and reduce graft-versus-host disease without impairing the graft-versus-leukemia effect von Haring, Eileen, Uhl, Franziska M., Andrieux, Geoffroy, Proietti, Michele, Bulashevska, Alla, Sauer, Barbara, Braun, Lukas M., Gomez, Enrique de Vega, Esser, Philipp R., Martin, Stefan F., Pfeifer, Dietmar, Follo, Marie, Schmitt-Graeff, Annette, Buescher, Joerg, Duyster, Justus, Grimbacher, Bodo, Boerries, Melanie, Pearce, Erika L., Zeiser, Robert, Apostolova, Petya

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Molecular consequences of SARS-CoV-2 liver tropism von Wanner, Nicola, Andrieux, Geoffroy, Badia-i-Mompel, Pau, Edler, Carolin, Pfefferle, Susanne, Lindenmeyer, Maja T., Schmidt-Lauber, Christian, Czogalla, Jan, Wong, Milagros N., Okabayashi, Yusuke, Braun, Fabian, Lütgehetmann, Marc, Meister, Elisabeth, Lu, Shun, Noriega, Maria L. M., Günther, Thomas, Grundhoff, Adam, Fischer, Nicole, Bräuninger, Hanna, Lindner, Diana, Westermann, Dirk, Haas, Fabian, Roedl, Kevin, Kluge, Stefan, Addo, Marylyn M., Huber, Samuel, Lohse, Ansgar W., Reiser, Jochen, Ondruschka, Benjamin, Sperhake, Jan P., Saez-Rodriguez, Julio, Boerries, Melanie, Hayek, Salim S., Aepfelbacher, Martin, Scaturro, Pietro, Puelles, Victor G., Huber, Tobias B.

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Early assessment of circulating tumor DNA after curative‐intent resection predicts tumor recurrence in early‐stage and locally advanced non‐small‐cell lung cancer von Waldeck, Silvia, Mitschke, Jan, Wiesemann, Sebastian, Rassner, Michael, Andrieux, Geoffroy, Deuter, Max, Mutter, Jurik, Lüchtenborg, Anne‐Marie, Kottmann, Daniel, Titze, Laurin, Zeisel, Christoph, Jolic, Martina, Philipp, Ulrike, Lassmann, Silke, Bronsert, Peter, Greil, Christine, Rawluk, Justyna, Becker, Heiko, Isbell, Lisa, Müller, Alexandra, Doostkam, Soroush, Passlick, Bernward, Börries, Melanie, Duyster, Justus, Wehrle, Julius, Scherer, Florian, von Bubnoff, Nikolas

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ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease von Maas-Bauer, Kristina, Stell, Anna-Verena, Yan, Kai-Li, de Vega, Enrique, Vinnakota, Janaki Manoja, Unger, Susanne, Núñez, Nicolas, Norona, Johana, Talvard-Balland, Nana, Koßmann, Stefanie, Schwan, Carsten, Miething, Cornelius, Martens, Uta S., Shoumariyeh, Khalid, Nestor, Rosa P., Duquesne, Sandra, Hanke, Kathrin, Rackiewicz, Michal, Hu, Zehan, El Khawanky, Nadia, Taromi, Sanaz, Andrlova, Hana, Faraidun, Hemin, Walter, Stefanie, Pfeifer, Dietmar, Follo, Marie, Waldschmidt, Johannes, Melchinger, Wolfgang, Rassner, Michael, Wehr, Claudia, Schmitt-Graeff, Annette, Halbach, Sebastian, Liao, James, Häcker, Georg, Brummer, Tilman, Dengjel, Joern, Andrieux, Geoffroy, Grosse, Robert, Tugues, Sonia, Blazar, Bruce R., Becher, Burkhard, Boerries, Melanie, Zeiser, Robert

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Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation von Hamarsheh, Shaima’a, Osswald, Lena, Saller, Benedikt S., Unger, Susanne, De Feo, Donatella, Vinnakota, Janaki Manoja, Konantz, Martina, Uhl, Franziska M., Becker, Heiko, Lübbert, Michael, Shoumariyeh, Khalid, Schürch, Christoph, Andrieux, Geoffroy, Venhoff, Nils, Schmitt-Graeff, Annette, Duquesne, Sandra, Pfeifer, Dietmar, Cooper, Matthew A., Lengerke, Claudia, Boerries, Melanie, Duyster, Justus, Niemeyer, Charlotte M., Erlacher, Miriam, Blazar, Bruce R., Becher, Burkard, Groß, Olaf, Brummer, Tilman, Zeiser, Robert

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USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING von Karlowitz, Rebekka, Stanifer, Megan L., Roedig, Jens, Andrieux, Geoffroy, Bojkova, Denisa, Bechtel, Marco, Smith, Sonja, Kowald, Lisa, Schubert, Ralf, Boerries, Melanie, Cinatl, Jindrich, Boulant, Steeve, van Wijk, Sjoerd J. L.

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Spatially resolved transcriptomic profiles reveal unique defining molecular features of infiltrative 5ALA-metabolizing cells associated with glioblastoma recurrence von Andrieux, Geoffroy, Das, Tonmoy, Griffin, Michaela, Straehle, Jakob, Paine, Simon M L, Beck, Jürgen, Boerries, Melanie, Heiland, Dieter H, Smith, Stuart J, Rahman, Ruman, Chakraborty, Sajib

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Alteration of Proteotranscriptomic Landscape Reveals the Transcriptional Regulatory Circuits Controlling Key-Signaling Pathways and Metabolic Reprogramming During Tumor Evolution von Andrieux, Geoffroy, Chakraborty, Sajib, Das, Tonmoy, Boerries, Melanie

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Oncogenic KrasG12D Activation in the Nonhematopoietic Bone Marrow Microenvironment Causes Myelodysplastic Syndrome in Mice von Osswald, Lena, Hamarsheh, Shaima'a, Uhl, Franziska Maria, Andrieux, Geoffroy, Klein, Claudius, Dierks, Christine, Duquesne, Sandra, Braun, Lukas M., Schmitt-Graeff, Annette, Duyster, Justus, Boerries, Melanie, Brummer, Tilman, Zeiser, Robert

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Cardiac Regeneration and Tumor Growth-What Do They Have in Common? von Dicks, Severin, Juergensen, Lonny, Leuschner, Florian, Hassel, David, Andrieux, Geoffroy, Boerries, Melanie

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Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo von Chakraborty, Sajib, Andrieux, Geoffroy, Kastl, Philipp, Adlung, Lorenz, Altamura, Sandro, Boehm, Martin E., Schwarzmüller, Luisa E., Abdullah, Yomn, Wagner, Marie-Christine, Helm, Barbara, Gröne, Hermann-Josef, Lehmann, Wolf D., Boerries, Melanie, Busch, Hauke, Muckenthaler, Martina U., Schilling, Marcel, Klingmüller, Ursula

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Gene editing of NCF1 loci is associated with homologous recombination and chromosomal rearrangements von Raimondi, Federica, Siow, Kah Mun, Wrona, Dominik, Fuster-García, Carla, Pastukhov, Oleksandr, Schmitz, Michael, Bargsten, Katja, Kissling, Lucas, Swarts, Daan C., Andrieux, Geoffroy, Cathomen, Toni, Modlich, Ute, Jinek, Martin, Siler, Ulrich, Reichenbach, Janine

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Dysregulated PI3K Signaling in B Cells of CVID Patients von Harder, Ina, Münchhalfen, Matthias, Andrieux, Geoffroy, Boerries, Melanie, Grimbacher, Bodo, Eibel, Hermann, Maccari, Maria Elena, Ehl, Stephan, Wienands, Jürgen, Jellusova, Julia, Warnatz, Klaus, Keller, Baerbel

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PUMA-INDUCED APOPTOSIS DRIVES BONE MARROW FAILURE UPON TELOMERE SHORTENING AND LEUKEMIA IN A MOUSE MODEL OF DYSKERATOSIS CONGENITA von Molnar, Christian, Bohler, Sheila, Rajak, Jovana, Weiss, Julia Miriam, Gonzalez-Mendez, Irene, Andrieux, Geoffroy, Demmerath, Eva-Maria, Wahl, Madeleine, Wendeburg, Lena, Göhring, Gudrun, Strahm, Brigitte, Steinemann, Doris, Rudelius, Martina, Börries, Melanie, Quintanilla-Martinez, Leticia, Niemeyer, Charlotte M., Labi, Verena, Erlacher, Miriam

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Calpain-mediated cleavage generates a ZBTB18 N-terminal product that regulates HIF1A signaling and glioblastoma metabolism von Masilamani, Anie P., Schulzki, Rana, Yuan, Shuai, Haase, Ira V., Kling, Eva, Dewes, Franziska, Andrieux, Geoffroy, Börries, Melanie, Schnell, Oliver, Heiland, Dieter H., Schilling, Oliver, Ferrarese, Roberto, Carro, Maria S.

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ZBTB18 inhibits SREBP-dependent lipid synthesis by halting CTBPs and LSD1 activity in glioblastoma von Ferrarese, Roberto, Izzo, Annalisa, Andrieux, Geoffroy, Lagies, Simon, Bartmuss, Johanna Paulina, Masilamani, Anie Priscilla, Wasilenko, Alix, Osti, Daniela, Faletti, Stefania, Schulzki, Rana, Yuan, Shuai, Kling, Eva, Ribecco, Valentino, Heiland, Dieter Henrik, Tholen, Stefan, Prinz, Marco, Pelicci, Giuliana, Kammerer, Bernd, Boerries, Melanie, Carro, Maria Stella

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