Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation von Toffalori, Cristina, Zito, Laura, Gambacorta, Valentina, Riba, Michela, Oliveira, Giacomo, Bucci, Gabriele, Barcella, Matteo, Spinelli, Orietta, Greco, Raffaella, Crucitti, Lara, Cieri, Nicoletta, Noviello, Maddalena, Manfredi, Francesco, Montaldo, Elisa, Ostuni, Renato, Naldini, Matteo M., Gentner, Bernhard, Waterhouse, Miguel, Zeiser, Robert, Finke, Jurgen, Hanoun, Maher, Beelen, Dietrich W., Gojo, Ivana, Luznik, Leo, Onozawa, Masahiro, Teshima, Takanori, Devillier, Raynier, Blaise, Didier, Halkes, Constantijn J. M., Griffioen, Marieke, Carrabba, Matteo G., Bernardi, Massimo, Peccatori, Jacopo, Barlassina, Cristina, Stupka, Elia, Lazarevic, Dejan, Tonon, Giovanni, Rambaldi, Alessandro, Cittaro, Davide, Bonini, Chiara, Fleischhauer, Katharina, Ciceri, Fabio, Vago, Luca

Volltext

Hematopoietic Stem- and Progenitor-Cell Gene Therapy for Hurler Syndrome von Gentner, Bernhard, Tucci, Francesca, Galimberti, Stefania, Fumagalli, Francesca, De Pellegrin, Maurizio, Silvani, Paolo, Camesasca, Chiara, Pontesilli, Silvia, Darin, Silvia, Ciotti, Francesca, Sarzana, Marina, Consiglieri, Giulia, Filisetti, Chiara, Forni, Giulia, Passerini, Laura, Tomasoni, Daniela, Cesana, Daniela, Calabria, Andrea, Spinozzi, Giulio, Cicalese, Maria-Pia, Calbi, Valeria, Migliavacca, Maddalena, Barzaghi, Federica, Ferrua, Francesca, Gallo, Vera, Miglietta, Simona, Zonari, Erika, Cheruku, Patali S, Forni, Claudia, Facchini, Marcella, Corti, Ambra, Gabaldo, Michela, Zancan, Stefano, Gasperini, Serena, Rovelli, Attilio, Boelens, Jaap-Jan, Jones, Simon A, Wynn, Robert, Baldoli, Cristina, Montini, Eugenio, Gregori, Silvia, Ciceri, Fabio, Valsecchi, Maria G, la Marca, Giancarlo, Parini, Rossella, Naldini, Luigi, Aiuti, Alessandro, Bernardo, Maria-Ester

Volltext

Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress von Montaldo, Elisa, Lusito, Eleonora, Bianchessi, Valentina, Caronni, Nicoletta, Scala, Serena, Basso-Ricci, Luca, Cantaffa, Carla, Masserdotti, Alice, Barilaro, Mattia, Barresi, Simona, Genua, Marco, Vittoria, Francesco Maria, Barbiera, Giulia, Lazarevic, Dejan, Messina, Carlo, Xue, Elisabetta, Marktel, Sarah, Tresoldi, Cristina, Milani, Raffaella, Ronchi, Paola, Gattillo, Salvatore, Santoleri, Luca, Di Micco, Raffaella, Ditadi, Andrea, Belfiori, Giulio, Aleotti, Francesca, Naldini, Matteo Maria, Gentner, Bernhard, Gardiman, Elisa, Tamassia, Nicola, Cassatella, Marco Antonio, Hidalgo, Andrés, Kwok, Immanuel, Ng, Lai Guan, Crippa, Stefano, Falconi, Massimo, Pettinella, Francesca, Scapini, Patrizia, Naldini, Luigi, Ciceri, Fabio, Aiuti, Alessandro, Ostuni, Renato

Volltext

Targeting the ANG2/TIE2 Axis Inhibits Tumor Growth and Metastasis by Impairing Angiogenesis and Disabling Rebounds of Proangiogenic Myeloid Cells von Mazzieri, Roberta, Pucci, Ferdinando, Moi, Davide, Zonari, Erika, Ranghetti, Anna, Berti, Alvise, Politi, Letterio S., Gentner, Bernhard, Brown, Jeffrey L., Naldini, Luigi, De Palma, Michele

Volltext

A role for miR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice von Zonari, Erika, Pucci, Ferdinando, Saini, Massimo, Mazzieri, Roberta, Politi, Letterio S., Gentner, Bernhard, Naldini, Luigi

Volltext

Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy von Zonari, Erika, Desantis, Giacomo, Petrillo, Carolina, Boccalatte, Francesco E., Lidonnici, Maria Rosa, Kajaste-Rudnitski, Anna, Aiuti, Alessandro, Ferrari, Giuliana, Naldini, Luigi, Gentner, Bernhard

Volltext

Longitudinal single-cell profiling of chemotherapy response in acute myeloid leukemia von Naldini, Matteo Maria, Casirati, Gabriele, Barcella, Matteo, Rancoita, Paola Maria Vittoria, Cosentino, Andrea, Caserta, Carolina, Pavesi, Francesca, Zonari, Erika, Desantis, Giacomo, Gilioli, Diego, Carrabba, Matteo Giovanni, Vago, Luca, Bernardi, Massimo, Di Micco, Raffaella, Di Serio, Clelia, Merelli, Ivan, Volpin, Monica, Montini, Eugenio, Ciceri, Fabio, Gentner, Bernhard

Volltext

Interferon gene therapy reprograms the leukemia microenvironment inducing protective immunity to multiple tumor antigens von Escobar, Giulia, Barbarossa, Luigi, Barbiera, Giulia, Norelli, Margherita, Genua, Marco, Ranghetti, Anna, Plati, Tiziana, Camisa, Barbara, Brombin, Chiara, Cittaro, Davide, Annoni, Andrea, Bondanza, Attilio, Ostuni, Renato, Gentner, Bernhard, Naldini, Luigi

Volltext

miR-142-3p Prevents Macrophage Differentiation during Cancer-Induced Myelopoiesis von Sonda, Nada, Simonato, Francesca, Peranzoni, Elisa, Calì, Bianca, Bortoluzzi, Stefania, Bisognin, Andrea, Wang, Ena, Marincola, Francesco M., Naldini, Luigi, Gentner, Bernhard, Trautwein, Christian, Sackett, Sara Dutton, Zanovello, Paola, Molon, Barbara, Bronte, Vincenzo

Volltext

Attenuation of miR-126 Activity Expands HSC In Vivo without Exhaustion von Lechman, Eric R., Gentner, Bernhard, van Galen, Peter, Giustacchini, Alice, Saini, Massimo, Boccalatte, Francesco E., Hiramatsu, Hidefumi, Restuccia, Umberto, Bachi, Angela, Voisin, Veronique, Bader, Gary D., Dick, John E., Naldini, Luigi

Volltext

A Double-Switch Vector System Positively Regulates Transgene Expression by Endogenous microRNA Expression (miR-ON Vector) von Amendola, Mario, Giustacchini, Alice, Gentner, Bernhard, Naldini, Luigi

Volltext

Myeloid cell‐based delivery of IFN‐γ reprograms the leukemia microenvironment and induces anti‐tumoral immune responses von Mucci, Adele, Antonarelli, Gabriele, Caserta, Carolina, Vittoria, Francesco Maria, Desantis, Giacomo, Pagani, Riccardo, Greco, Beatrice, Casucci, Monica, Escobar, Giulia, Passerini, Laura, Lachmann, Nico, Sanvito, Francesca, Barcella, Matteo, Merelli, Ivan, Naldini, Luigi, Gentner, Bernhard

Volltext

Lentiviral vectors escape innate sensing but trigger p53 in human hematopoietic stem and progenitor cells von Piras, Francesco, Riba, Michela, Petrillo, Carolina, Lazarevic, Dejan, Cuccovillo, Ivan, Bartolaccini, Sara, Stupka, Elia, Gentner, Bernhard, Cittaro, Davide, Naldini, Luigi, Kajaste‐Rudnitski, Anna

Volltext

Hematopoietic Tumors in a Mouse Model of X-linked Chronic Granulomatous Disease after Lentiviral Vector-Mediated Gene Therapy von Jofra Hernández, Raisa, Calabria, Andrea, Sanvito, Francesca, De Mattia, Fabiola, Farinelli, Giada, Scala, Serena, Visigalli, Ilaria, Carriglio, Nicola, De Simone, Maura, Vezzoli, Michela, Cecere, Francesca, Migliavacca, Maddalena, Basso-Ricci, Luca, Omrani, Maryam, Benedicenti, Fabrizio, Norata, Rossana, Rancoita, Paola Maria Vittoria, Di Serio, Clelia, Albertini, Paola, Cristofori, Patrizia, Naldini, Luigi, Gentner, Bernhard, Montini, Eugenio, Aiuti, Alessandro, Mortellaro, Alessandra

Volltext

A case of T-cell acute lymphoblastic leukemia in retroviral gene therapy for ADA-SCID von Cesana, Daniela, Cicalese, Maria Pia, Calabria, Andrea, Merli, Pietro, Caruso, Roberta, Volpin, Monica, Rudilosso, Laura, Migliavacca, Maddalena, Barzaghi, Federica, Fossati, Claudia, Gazzo, Francesco, Pizzi, Simone, Ciolfi, Andrea, Bruselles, Alessandro, Tucci, Francesca, Spinozzi, Giulio, Pais, Giulia, Benedicenti, Fabrizio, Barcella, Matteo, Merelli, Ivan, Gallina, Pierangela, Giannelli, Stefania, Dionisio, Francesca, Scala, Serena, Casiraghi, Miriam, Strocchio, Luisa, Vinti, Luciana, Pacillo, Lucia, Draghi, Eleonora, Cesana, Marcella, Riccardo, Sara, Colantuono, Chiara, Six, Emmanuelle, Cavazzana, Marina, Carlucci, Filippo, Schmidt, Manfred, Cancrini, Caterina, Ciceri, Fabio, Vago, Luca, Cacchiarelli, Davide, Gentner, Bernhard, Naldini, Luigi, Tartaglia, Marco, Montini, Eugenio, Locatelli, Franco, Aiuti, Alessandro

Volltext

Expanded circulating hematopoietic stem/progenitor cells as novel cell source or the treatment of TCIRG1 osteopetrosis von Capo, Valentina, Penna, Sara, Merelli, Ivan, Barcella, Matteo, Scala, Serena, Basso-Ricci, Luca, Draghici, Elena, Palagano, Eleonora, Zonari, Erika, Desantis, Giacomo, Uva, Paolo, Cusano, Roberto, Sergi, Lucia Sergi, Crisafulli, Laura, Moshous, Despina, Stepensky, Polina, Drabko, Katarzyna, Kaya, Zuhre, Unal, Ekrem, Gezdirici, Alper, Menna, Giuseppe, Serafini, Marta, Aiuti, Alessandro, Locatelli, Silvia Laura, Carlo-Stella, Carmelo, Schulz, Ansgar S., Ficara, Francesca, Sobacchi, Cristina, Gentner, Bernhard, Villa, Anna

Volltext

Gene therapy for mucopolysaccharidoses: in vivo and ex vivo approaches von Fraldi, Alessandro, Serafini, Marta, Sorrentino, Nicolina Cristina, Gentner, Bernhard, Aiuti, Alessandro, Bernardo, Maria Ester

Volltext

MicroRNA-127-3p controls murine hematopoietic stem cell maintenance by limiting differentiation von Crisafulli, Laura, Muggeo, Sharon, Uva, Paolo, Wang, Yulei, Iwasaki, Masayuki, Locatelli, Silvia, Anselmo, Achille, Colombo, Federico S, Carlo-Stella, Carmelo, Cleary, Michael L, Villa, Anna, Gentner, Bernhard, Ficara, Francesca

Volltext

Plerixafor and G-CSF combination mobilizes hematopoietic stem and progenitors cells with a distinct transcriptional profile and a reduced in vivo homing capacity compared to plerix... von Lidonnici, Maria Rosa, Aprile, Annamaria, Frittoli, Marta Claudia, Mandelli, Giacomo, Paleari, Ylenia, Spinelli, Antonello, Gentner, Bernhard, Zambelli, Matilde, Parisi, Cristina, Bellio, Laura, Cassinerio, Elena, Zanaboni, Laura, Cappellini, Maria Domenica, Ciceri, Fabio, Marktel, Sarah, Ferrari, Giuliana

Volltext

The transcription factor HIF2α partakes in the differentiation block of acute myeloid leukemia von Magliulo, Daniela, Simoni, Matilde, Caserta, Carolina, Fracassi, Cristina, Belluschi, Serena, Giannetti, Kety, Pini, Raffaella, Zapparoli, Ettore, Beretta, Stefano, Uggè, Martina, Draghi, Eleonora, Rossari, Federico, Coltella, Nadia, Tresoldi, Cristina, Morelli, Marco J, Di Micco, Raffaella, Gentner, Bernhard, Vago, Luca, Bernardi, Rosa

Volltext