Small-Molecule Inhibitors of Cyclophilins Block Opening of the Mitochondrial Permeability Transition Pore and Protect Mice From Hepatic Ischemia/Reperfusion Injury von Panel, Mathieu, Ruiz, Isaac, Brillet, Rozenn, Lafdil, Fouad, Teixeira-Clerc, Fatima, Nguyen, Cong Trung, Calderaro, Julien, Gelin, Muriel, Allemand, Fred, Guichou, Jean-François, Ghaleh, Bijan, Ahmed-Belkacem, Abdelhakim, Morin, Didier, Pawlotsky, Jean-Michel

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Fragment-based discovery of a new family of non-peptidic small-molecule cyclophilin inhibitors with potent antiviral activities von Ahmed-Belkacem, Abdelhakim, Colliandre, Lionel, Ahnou, Nazim, Nevers, Quentin, Gelin, Muriel, Bessin, Yannick, Brillet, Rozenn, Cala, Olivier, Douguet, Dominique, Bourguet, William, Krimm, Isabelle, Pawlotsky, Jean-Michel, Guichou, Jean- François

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New Chemical Probe Targeting Bacterial NAD Kinase von Clément, David A, Leseigneur, Clarisse, Gelin, Muriel, Coelho, Dylan, Huteau, Valérie, Lionne, Corinne, Labesse, Gilles, Dussurget, Olivier, Pochet, Sylvie

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Toward the Design of Ligands Selective for the C-Terminal Domain of TEADs von Liberelle, Maxime, Toulotte, Florine, Renault, Nicolas, Gelin, Muriel, Allemand, Frédéric, Melnyk, Patricia, Guichou, Jean-François, Cotelle, Philippe

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Towards the design of ligands of the internal pocket TEADs C-terminal domain von Toulotte, Florine, Coevoet, Mathilde, Liberelle, Maxime, Bailly, Fabrice, Zagiel, Benjamin, Gelin, Muriel, Allemand, Frédéric, Fourquet, Patrick, Melnyk, Patricia, Guichou, Jean-François, Cotelle, Philippe

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Crystal structure of human NADK2 reveals a dimeric organization and active site occlusion by lysine acetylation von Mary, Charline, Soflaee, Mona Hoseini, Kesavan, Rushendhiran, Gelin, Muriel, Brown, Harrison, Zacharias, G, Mathews, Thomas P, Lemoff, Andrew, Lionne, Corinne, Labesse, Gilles, Hoxhaj, Gerta

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Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMPDHs von Gedeon, Antoine, Ayoub, Nour, Brûlé, Sébastien, Raynal, Bertrand, Karimova, Gouzel, Gelin, Muriel, Mechaly, Ariel, Haouz, Ahmed, Labesse, Gilles, Munier-Lehmann, Hélène

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w TSA-CRAFT : an open-access web server for rapid analysis of thermal shift assay experiments von Reys, Victor, Kowalewski, Julien, Gelin, Muriel, Lionne, Corinne

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wTSA-CRAFT: an open-access web server for rapid analysis of thermal shift assay experiments von Reys, Victor, Kowalewski, Julien, Gelin, Muriel, Lionne, Corinne

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Insight into the role of the Bateman domain at the molecular and physiological levels through engineered IMP dehydrogenases von Gedeon, Antoine, Ayoub, Nour, Brûlé, Sébastien, Raynal, Bertrand, Karimova, Gouzel, Gelin, Muriel, Mechaly, Ariel, Haouz, Ahmed, Labesse, Gilles, Munier‐Lehmann, Hélène

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Discovery of a cryptic site at the interface 2 of TEAD – Towards a new family of YAP/TAZ-TEAD inhibitors von Sturbaut, Manon, Bailly, Fabrice, Coevoet, Mathilde, Sileo, Pasquale, Pugniere, Martine, Liberelle, Maxime, Magnez, Romain, Thuru, Xavier, Chartier-Harlin, Marie-Christine, Melnyk, Patricia, Gelin, Muriel, Allemand, Frédéric, Guichou, Jean-François, Cotelle, Philippe

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Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding von Schneider, Melanie, Delfosse, Vanessa, Gelin, Muriel, Grimaldi, Marina, Granell, Meritxell, Heriaud, Laurène, Pons, Jean-Luc, Cohen Gonsaud, Martin, Balaguer, Patrick, Bourguet, William, Labesse, Gilles

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Structure-Based and Knowledge-Informed Design of B‑Raf Inhibitors Devoid of Deleterious PXR Binding von Schneider, Melanie, Delfosse, Vanessa, Gelin, Muriel, Grimaldi, Marina, Granell, Meritxell, Heriaud, Laurène, Pons, Jean-Luc, Cohen Gonsaud, Martin, Balaguer, Patrick, Bourguet, William, Labesse, Gilles

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Synthesis and structure-activity relationship studies of original cyclic diadenosine derivatives as nanomolar inhibitors of NAD kinase from pathogenic bacteria von Clément, David A., Gelin, Muriel, Leseigneur, Clarisse, Huteau, Valérie, Mondange, Lou, Pons, Jean-Luc, Dussurget, Olivier, Lionne, Corinne, Labesse, Gilles, Pochet, Sylvie

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Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation von Lecointre, Céline, Simon, Valérie, Kerneur, Clément, Allemand, Frédéric, Fournet, Aurélie, Montarras, Ingrid, Pons, Jean-Luc, Gelin, Muriel, Brignatz, Constance, Urbach, Serge, Labesse, Gilles, Roche, Serge

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Development of LM-41 and AF-2112, two flufenamic acid-derived TEAD inhibitors obtained through the replacement of the trifluoromethyl group by aryl rings von Fnaiche, Ahmed, Mélin, Léa, Suárez, Narjara González, Paquin, Alexis, Vu, Victoria, Li, Fengling, Allali-Hassani, Abdellah, Bolotokova, Albina, Allemand, Frédéric, Gelin, Muriel, Cotelle, Philippe, Woo, Simon, LaPlante, Steven R., Barsyte-Lovejoy, Dalia, Santhakumar, Vijayaratnam, Vedadi, Masoud, Guichou, Jean-François, Annabi, Borhane, Gagnon, Alexandre

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Structure-Based and Knowledge-Informed Design of B-Raf Inhibitors Devoid of Deleterious PXR Binding von Schneider, Melanie, Delfosse, Vanessa, Gelin, Muriel, Grimaldi, Marina, Granell, Meritxell, Heriaud, Laurène, Pons, Jean-Luc, Cohen Gonsaud, Martin, Balaguer, Patrick, Bourguet, William, Labesse, Gilles

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First-in-class allosteric inhibitors of bacterial IMPDHs von Alexandre, Thomas, Lupan, Alexandru, Helynck, Olivier, Vichier-Guerre, Sophie, Dugué, Laurence, Gelin, Muriel, Haouz, Ahmed, Labesse, Gilles, Munier-Lehmann, Hélène

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Structure‐based design, synthesis and biological evaluation of a NAD+ analogue targeting Pseudomonas aeruginosa NAD kinase von Rahimova, Rahila, Nogaret, Pauline, Huteau, Valérie, Gelin, Muriel, Clément, David A., Labesse, Gilles, Pochet, Sylvie, Blanc‐Potard, Anne‐Béatrice, Lionne, Corinne

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Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation von Labesse, Gilles, Alexandre, Thomas, Gelin, Muriel, Haouz, Ahmed, Munier-Lehmann, Hélène

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