A Dipolar Cycloaddition Reaction To Access 6‑Methyl-4,5,6,7-tetrahydro‑1H‑[1,2,3]­triazolo[4,5‑c]­pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 Anta... von Chrovian, Christa C, Soyode-Johnson, Akinola, Peterson, Alexander A, Gelin, Christine F, Deng, Xiaohu, Dvorak, Curt A, Carruthers, Nicholas I, Lord, Brian, Fraser, Ian, Aluisio, Leah, Coe, Kevin J, Scott, Brian, Koudriakova, Tatiana, Schoetens, Freddy, Sepassi, Kia, Gallacher, David J, Bhattacharya, Anindya, Letavic, Michael A

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Discovery of a Series of Substituted 1H‑((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators von Gelin, Christine F., Stenne, Brice, Coate, Heather, Hiscox, Afton, Soyode-Johnson, Akinola, Wall, Jessica L., Lord, Brian, Schoellerman, Jeffrey, Coe, Kevin J., Wang, Kai, Alcázar, Jesus, Chrovian, Christa C., Dvorak, Curt A., Carruthers, Nicholas I., Koudriakova, Tatiana, Balana, Bartosz, Letavic, Michael A.

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Discovery of a Series of Substituted 1 H -((1,2,3-Triazol-4-yl)methoxy)pyrimidines as Brain Penetrants and Potent GluN2B-Selective Negative Allosteric Modulators von Gelin, Christine F, Stenne, Brice, Coate, Heather, Hiscox, Afton, Soyode-Johnson, Akinola, Wall, Jessica L, Lord, Brian, Schoellerman, Jeffrey, Coe, Kevin J, Wang, Kai, Alcázar, Jesus, Chrovian, Christa C, Dvorak, Curt A, Carruthers, Nicholas I, Koudriakova, Tatiana, Balana, Bartosz, Letavic, Michael A

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Identification of a Novel Small Molecule HIF-1α Translation Inhibitor von NARITA, Takuhito, SHAOMAN YIN, GELIN, Christine F, MORENO, Carlos S, YEPES, Manuel, NICOLAOU, K. C, VAN MEIR, Erwin G

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4‑Methyl-6,7-dihydro‑4H‑triazolo[4,5‑c]­pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidate... von Letavic, Michael A, Savall, Brad M, Allison, Brett D, Aluisio, Leah, Andres, Jose Ignacio, De Angelis, Meri, Ao, Hong, Beauchamp, Derek A, Bonaventure, Pascal, Bryant, Stewart, Carruthers, Nicholas I, Ceusters, Marc, Coe, Kevin J, Dvorak, Curt A, Fraser, Ian C, Gelin, Christine F, Koudriakova, Tatiana, Liang, Jimmy, Lord, Brian, Lovenberg, Timothy W, Otieno, Monicah A, Schoetens, Freddy, Swanson, Devin M, Wang, Qi, Wickenden, Alan D, Bhattacharya, Anindya

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Development of small molecule inhibitors of natural killer group 2D receptor (NKG2D) von Wang, Jocelyn, Nakafuku, Kohki M., Ziff, Jeannie, Gelin, Christine F., Gholami, Hadi, Thompson, Aaron A., Karpowich, Nathan K., Limon, Luis, Coate, Heather R., Damm-Ganamet, Kelly L., Shih, Amy Y., Grant, Joanna C., Côte, Marjorie, Mak, Puiying A., Pascual, Heather A., Rives, Marie-Laure, Edwards, James P., Venable, Jennifer D., Venkatesan, Hariharan, Shi, Zhicai, Allen, Samantha J., Sharma, Sujata, Kung, Pei-Pei, Shireman, Brock T.

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Identification of small-molecule protein-protein interaction inhibitors for NKG2D von Thompson, Aaron A, Harbut, Michael B, Kung, Pei-Pei, Karpowich, Nathan K, Branson, Jeffrey D, Grant, Joanna C, Hagan, Deborah, Pascual, Heather A, Bai, Guoyun, Zavareh, Reza Beheshti, Coate, Heather R, Collins, Bernard C, Côte, Marjorie, Gelin, Christine F, Damm-Ganamet, Kelly L, Gholami, Hadi, Huff, Adam R, Limon, Luis, Lumb, Kevin J, Mak, Puiying A, Nakafuku, Kohki M, Price, Edmund V, Shih, Amy Y, Tootoonchi, Mandana, Vellore, Nadeem A, Wang, Jocelyn, Wei, Na, Ziff, Jeannie, Berger, Scott B, Edwards, James P, Gardet, Agnès, Sun, Siquan, Towne, Jennifer E, Venable, Jennifer D, Shi, Zhicai, Venkatesan, Hariharan, Rives, Marie-Laure, Sharma, Sujata, Shireman, Brock T, Allen, Samantha J

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Design, Synthesis, and Preclinical Characterization of Selective Factor D Inhibitors Targeting the Alternative Complement Pathway von Karki, Rajeshri G, Powers, James, Mainolfi, Nello, Anderson, Karen, Belanger, David B, Liu, Donglei, Ji, Nan, Jendza, Keith, Gelin, Christine F, Mac Sweeney, Aengus, Solovay, Catherine, Delgado, Omar, Crowley, Maura, Liao, Sha-Mei, Argikar, Upendra A, Flohr, Stefanie, La Bonte, Laura R, Lorthiois, Edwige L, Vulpetti, Anna, Brown, Ann, Long, Debby, Prentiss, Melissa, Gradoux, Nathalie, de Erkenez, Andrea, Cumin, Frederic, Adams, Christopher, Jaffee, Bruce, Mogi, Muneto

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Synthesis of the QRSTU Domain of Maitotoxin and Its 85-epi- and 86-epi-Diastereoisomers von Nicolaou, K. C, Gelin, Christine F, Seo, Jae Hong, Huang, Zhihong, Umezawa, Taiki

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Cascade Reactions Involving Formal [2+2] Thermal Cycloadditions: Total Synthesis of Artochamins F, H, I, and J von Nicolaou, K.C, Lister, Troy, Denton, Ross M, Gelin, Christine F

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Modulating the Potency of BRD4 PROTACs at the Systems Level with Amine-Acid Coupling Reactions von McGrath, Andrew, Huang, Haiyan, Brazeau, Jean-Francois, Zhang, Zirong, Audu, Christopher O, Vellore, Nadeem A, Zhu, Lu, Shi, Zhicai, Venable, Jennifer D, Gelin, Christine F, Cernak, Tim

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Total synthesis of atrochamins F, H, I, and J through cascade reactions von Nicolaou, K C, Lister, Troy, Denton, Ross M, Gelin, Christine F

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A Dipolar Cycloaddition Reaction To Access 6-Methyl-4,5,6,7-tetrahydro-1 H -[1,2,3]triazolo[4,5- c ]pyridines Enables the Discovery Synthesis and Preclinical Profiling of a P2X7 An... von Chrovian, Christa C., Soyode-Johnson, Akinola, Peterson, Alexander A., Gelin, Christine F., Deng, Xiaohu, Dvorak, Curt A., Carruthers, Nicholas I., Lord, Brian, Fraser, Ian, Aluisio, Leah, Coe, Kevin J., Scott, Brian, Koudriakova, Tatiana, Schoetens, Freddy, Sepassi, Kia, Gallacher, David J., Bhattacharya, Anindya, Letavic, Michael A.

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4-Methyl-6,7-dihydro-4 H -triazolo[4,5- c ]pyridine-Based P2X7 Receptor Antagonists: Optimization of Pharmacokinetic Properties Leading to the Identification of a Clinical Candidat... von Letavic, Michael A., Savall, Brad M., Allison, Brett D., Aluisio, Leah, Andres, Jose Ignacio, De Angelis, Meri, Ao, Hong, Beauchamp, Derek A., Bonaventure, Pascal, Bryant, Stewart, Carruthers, Nicholas I., Ceusters, Marc, Coe, Kevin J., Dvorak, Curt A., Fraser, Ian C., Gelin, Christine F., Koudriakova, Tatiana, Liang, Jimmy, Lord, Brian, Lovenberg, Timothy W., Otieno, Monicah A., Schoetens, Freddy, Swanson, Devin M., Wang, Qi, Wickenden, Alan D., Bhattacharya, Anindya

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Pyrazine carbamates and their use as GluN2B receptor modulators von Gelin, Christine

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Total synthesis of artochamins F, H, I, and J through cascade reactions von Nicolaou, K.C., Lister, Troy, Denton, Ross M., Gelin, Christine F.

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PYRAZINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS von GELIN, Christine

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Pyrazine carbamates and their use as GluN2B receptor modulators von GELIN, Christine

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PYRAZINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS von GELIN, CHRISTINE

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PYRAZINE CARBAMATES AND THEIR USE AS GLUN2B RECEPTOR MODULATORS von GELIN, Christine

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