Metabolic dysfunction and cancer in HCV: Shared pathways and mutual interactions von Leslie, Jack, Geh, Daniel, Elsharkawy, Ahmed M., Mann, Derek A., Vacca, Michele

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Immunomodulatory Effects of Lenvatinib Plus Anti–Programmed Cell Death Protein 1 in Mice and Rationale for Patient Enrichment in Hepatocellular Carcinoma von Torrens, Laura, Montironi, Carla, Puigvehí, Marc, Mesropian, Agavni, Leslie, Jack, Haber, Philipp K., Maeda, Miho, Balaseviciute, Ugne, Willoughby, Catherine E., Abril‐Fornaguera, Jordi, Piqué‐Gili, Marta, Torres‐Martín, Miguel, Peix, Judit, Geh, Daniel, Ramon‐Gil, Erik, Saberi, Behnam, Friedman, Scott L., Mann, Derek A., Sia, Daniela, Llovet, Josep M.

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Biliary epithelium and liver B cells exposed to bacteria activate intrahepatic MAIT cells through MR1 von Jeffery, Hannah C, van Wilgenburg, Bonnie, Kurioka, Ayako, Parekh, Krishan, Stirling, Kathryn, Roberts, Sheree, Dutton, Emma E, Hunter, Stuart, Geh, Daniel, Braitch, Manjit K, Rajanayagam, Jeremy, Iqbal, Tariq, Pinkney, Thomas, Brown, Rachel, Withers, David R, Adams, David H, Klenerman, Paul, Oo, Ye H

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Hepatocellular carcinoma in non-alcoholic fatty liver disease—a review of an emerging challenge facing clinicians von Geh, Daniel, Manas, Derek M., Reeves, Helen L.

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COVID-19 and liver cancer: lost patients and larger tumours von Geh, Daniel, Watson, Robyn, Sen, Gourab, French, Jeremy J, Hammond, John, Turner, Paul, Hoare, Tim, Anderson, Kirsty, McNeil, Michael, McPherson, Stuart, Masson, Steven, Dyson, Jessica, Donnelly, Mhairi, MacDougal, Louise, Patel, Preya, Hudson, Mark, Anstee, Quentin M, White, Steven, Robinson, Stuart, Pandanaboyana, Sanjay, Walker, Lucy, McCain, Misti, Bury, Yvonne, Raman, Shreya, Burt, Alastair, Parkinson, Daniel, Haugk, Beate, Darne, Antony, Wadd, Nick, Asghar, Syed, Mariappan, Lavanya, Margetts, Jane, Stenberg, Benjamin, Scott, John, Littler, Peter, Manas, Derek M, Reeves, Helen L

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ST3 beta-galactoside alpha-2,3-sialyltransferase 1 (ST3Gal1) synthesis of Siglec ligands mediates anti-tumour immunity in prostate cancer von Garnham, Rebecca, Geh, Daniel, Nelson, Ryan, Ramon-Gil, Erik, Wilson, Laura, Schmidt, Edward N., Walker, Laura, Adamson, Beth, Buskin, Adriana, Hepburn, Anastasia C., Hodgson, Kirsty, Kendall, Hannah, Frame, Fiona M., Maitland, Norman, Coffey, Kelly, Strand, Douglas W., Robson, Craig N., Elliott, David J., Heer, Rakesh, Macauley, Matthew, Munkley, Jennifer, Gaughan, Luke, Leslie, Jack, Scott, Emma

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Sulfatase-2 from Cancer Associated Fibroblasts: An Environmental Target for Hepatocellular Carcinoma? von Zaki, Marco Y.W., Alhasan, Sari F., Shukla, Ruchi, McCain, Misti, Laszczewska, Maja, Geh, Daniel, Patman, Gillian L., Televantou, Despina, Whitehead, Anna, Maurício, João P., Barksby, Ben, Gee, Lucy M., Paish, Hannah L., Leslie, Jack, Younes, Ramy, Burt, Alastair D., Borthwick, Lee A., Thomas, Huw, Beale, Gary S., Govaere, Olivier, Sia, Daniela, Anstee, Quentin M., Tiniakos, Dina, Oakley, Fiona, Reeves, Helen L.

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Neutrophils as potential therapeutic targets in hepatocellular carcinoma von Geh, Daniel, Leslie, Jack, Rumney, Rob, Reeves, Helen L., Bird, Thomas G., Mann, Derek A.

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CXCR2 inhibition enables NASH-HCC immunotherapy von Leslie, Jack, Mackey, John B G, Jamieson, Thomas, Ramon-Gil, Erik, Drake, Thomas M, Fercoq, Frédéric, Clark, William, Gilroy, Kathryn, Hedley, Ann, Nixon, Colin, Luli, Saimir, Laszczewska, Maja, Pinyol, Roser, Esteban-Fabró, Roger, Willoughby, Catherine E, Haber, Philipp K, Andreu-Oller, Carmen, Rahbari, Mohammad, Fan, Chaofan, Pfister, Dominik, Raman, Shreya, Wilson, Niall, Müller, Miryam, Collins, Amy, Geh, Daniel, Fuller, Andrew, McDonald, David, Hulme, Gillian, Filby, Andrew, Cortes-Lavaud, Xabier, Mohamed, Noha-Ehssan, Ford, Catriona A, Raffo Iraolagoitia, Ximena L, McFarlane, Amanda J, McCain, Misti V, Ridgway, Rachel A, Roberts, Edward W, Barry, Simon T, Graham, Gerard J, Heikenwälder, Mathias, Reeves, Helen L, Llovet, Josep M, Carlin, Leo M, Bird, Thomas G, Sansom, Owen J, Mann, Derek A

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Neutrophils induce paracrine telomere dysfunction and senescence in ROS‐dependent manner von Lagnado, Anthony, Leslie, Jack, Ruchaud‐Sparagano, Marie‐Helene, Victorelli, Stella, Hirsova, Petra, Ogrodnik, Mikolaj, Collins, Amy L, Vizioli, Maria Grazia, Habiballa, Leena, Saretzki, Gabriele, Evans, Shane A, Salmonowicz, Hanna, Hruby, Adam, Geh, Daniel, Pavelko, Kevin D, Dolan, David, Reeves, Helen L, Grellscheid, Sushma, Wilson, Colin H, Pandanaboyana, Sanjay, Doolittle, Madison, von Zglinicki, Thomas, Oakley, Fiona, Gallage, Suchira, Wilson, Caroline L, Birch, Jodie, Carroll, Bernadette, Chapman, James, Heikenwalder, Mathias, Neretti, Nicola, Khosla, Sundeep, Masuda, Claudio Akio, Tchkonia, Tamar, Kirkland, James L, Jurk, Diana, Mann, Derek A, Passos, João F

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SAT-234 - Immunotherapy resistance in NASH-HCC is driven by the dysfunctional liver microenvironment of NASH von Geh, Daniel, Gil, Erik Ramon, Laszczewska, Maja, Collins, Amy, Luli, Saimir, Cameron, Rainie, Oakley, Fiona, Leslie, Jack, Reeves, Helen Louise, Mann, Derek A

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Neutrophil degranulation and ageing as potential therapeutic targets in hepatocellular carcinoma? von Geh, Daniel, Gil, Erik Ramon, Laszczewska, Maja, Collins, Amy, Luli, Saimir, Cameron, Rainie, Oakley, Fiona, Reeves, Helen Louise, Mann, Derek A, Leslie, Jack

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SAT-284 - Modelling hepatocellular carcinoma in precision-cut liver slices for therapeutic screening and as a precision medicine tool von Collins, Amy, Leslie, Jack, Geh, Daniel, Gil, Erik Ramon, Laszczewska, Maja, Nelson, Glyn, Cameron, Rainie, Dalgarno, Kenny, Reeves, Helen Louise, Mann, Derek A, Oakley, Fiona

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Modelling hepatocellular carcinoma in precision-cut liver slices for therapeutic screening and as a precision medicine tool von Collins, Amy, Leslie, Jack, Geh, Daniel, Gil, Erik Ramon, Laszczewska, Maja, Nelson, Glyn, Cameron, Rainie, Dalgarno, Kenny, Reeves, Helen Louise, Mann, Derek A, Oakley, Fiona

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Immunotherapy resistance in NASH-HCC is driven by the dysfunctional liver microenvironment of NASH von Geh, Daniel, Gil, Erik Ramon, Laszczewska, Maja, Collins, Amy, Luli, Saimir, Cameron, Rainie, Oakley, Fiona, Leslie, Jack, Reeves, Helen Louise, Mann, Derek A

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SAT-239 - Neutrophil degranulation and ageing as potential therapeutic targets in hepatocellular carcinoma? von Geh, Daniel, Gil, Erik Ramon, Laszczewska, Maja, Collins, Amy, Luli, Saimir, Cameron, Rainie, Oakley, Fiona, Reeves, Helen Louise, Mann, Derek A, Leslie, Jack

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Tracking neutrophils within the hepatocellular carcinoma microenvironment - development of relevant orthotopic and ex-vivo 3D liver-HCC culture models von Geh, Daniel, Collins, Amy, Wilson, Caroline, Reeves, Helen L., Mann, Derek A, Leslie, Jack

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FRI472 - Tracking neutrophils within the hepatocellular carcinoma microenvironment - development of relevant orthotopic and ex-vivo 3D liver-HCC culture models von Geh, Daniel, Collins, Amy, Wilson, Caroline, Reeves, Helen L., Mann, Derek A, Leslie, Jack

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P099 Serum gamma glutamyl transferase (γGT) – a prognostic biomarker for detrimental neutrophils in patients with hepatocellular carcinoma (HCC)? von Kadharusman, Marcello, McCain, Misti, Mauricio, Joao, Laszczewska, Maja, Leslie, Jack, Geh, Daniel, Mann, Derek, Shukla, Ruchi, Reeves, Helen L

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NAFLD-Associated HCC: Progress and Opportunities von Geh, Daniel, Anstee, Quentin M, Reeves, Helen L

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