Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors von Gazdar, A F

Volltext

Genomic profiling identifies TITF1 as a lineage-specific oncogene amplified in lung cancer von Kwei, K A, Kim, Y H, Girard, L, Kao, J, Pacyna-Gengelbach, M, Salari, K, Lee, J, Choi, Y-L, Sato, M, Wang, P, Hernandez-Boussard, T, Gazdar, A F, Petersen, I, Minna, J D, Pollack, J R

Volltext

Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small-cell lung cancer patients treated with gefitinib von Hirsch, FR, Varella-Garcia, M, Cappuzzo, F, McCoy, J, Bemis, L, Xavier, AC, Dziadziuszko, R, Gumerlock, P, Chansky, K, West, H, Gazdar, AF, Crino, L, Gandara, DR, Franklin, WA, Bunn, PA

Volltext

Genomic and functional analysis identifies CRKL as an oncogene amplified in lung cancer von Kim, Y H, Kwei, K A, Girard, L, Salari, K, Kao, J, Pacyna-Gengelbach, M, Wang, P, Hernandez-Boussard, T, Gazdar, A F, Petersen, I, Minna, J D, Pollack, J R

Volltext

DNA amplification is a ubiquitous mechanism of oncogene activation in lung and other cancers von Lockwood, W W, Chari, R, Coe, B P, Girard, L, MacAulay, C, Lam, S, Gazdar, A F, Minna, J D, Lam, W L

Volltext

Epidermal growth factor receptor regulates MET levels and invasiveness through hypoxia-inducible factor-1α in non-small cell lung cancer cells von Xu, L, Nilsson, M B, Saintigny, P, Cascone, T, Herynk, M H, Du, Z, Nikolinakos, P G, Yang, Y, Prudkin, L, Liu, D, Lee, J J, Johnson, F M, Wong, K-K, Girard, L, Gazdar, A F, Minna, J D, Kurie, J M, Wistuba, I I, Heymach, J V

Volltext

Epigenetic Inactivation of RASSF1A in Lung and Breast Cancers and Malignant Phenotype Suppression von Burbee, David G., Forgacs, Eva, Zöchbauer-Müller, Sabine, Shivakumar, Latha, Fong, Kwun, Gao, Boning, Randle, Dwight, Kondo, Masashi, Virmani, Arvind, Bader, Scott, Sekido, Yoshitaka, Latif, Farida, Milchgrub, Sara, Toyooka, Shinichi, Gazdar, Adi F., Lerman, Michael I., Zabarovsky, Eugene, White, Michael, Minna, John D.

Volltext

Oncogenic KRAS-induced epiregulin overexpression contributes to aggressive phenotype and is a promising therapeutic target in non-small-cell lung cancer von Sunaga, N, Kaira, K, Imai, H, Shimizu, K, Nakano, T, Shames, D S, Girard, L, Soh, J, Sato, M, Iwasaki, Y, Ishizuka, T, Gazdar, A F, Minna, J D, Mori, M

Volltext

Lung cancer • 9: Molecular biology of lung cancer: clinical implications von Fong, K M, Sekido, Y, Gazdar, A F, Minna, J D

Volltext

Molecular damage in the bronchial epithelium of current and former smokers von WISTUBA, I. I, LAM, S, BEHRENS, C, VIRMANI, A. K, FONG, K. M, LERICHE, J, SAMET, J. M, SRIVASTAVA, S, MINNA, J. D, GAZDAR, A. F

Volltext

Chromosome 19 Translocation, Overexpression of Notch3, and Human Lung Cancer von Dang, Thao P., Gazdar, Adi F., Virmani, Arvind K., Sepetavec, Tanya, Hande, Kenneth R., Minna, John D., Roberts, John R., Carbone, David P.

Volltext

Aberrant methylation of SPARC in human lung cancers von Suzuki, M, Hao, C, Takahashi, T, Shigematsu, H, Shivapurkar, N, Sathyanarayana, U G, Iizasa, T, Fujisawa, T, Hiroshima, K, Gazdar, A F

Volltext

Telomerase Activity in Small-Cell and Non–Small-Cell Lung Cancers von Hiyama, Keiko, Hiyama, Eiso, Ishioka, Shinichi, Yamakido, Michio, Inai, Kouki, Gazdar, Adi F., Piatyszek, Mieczyslaw A., Shay, Jerry W.

Volltext

Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering von GIRARD, Luc, ZÖCHBAUER-MÜLLER, Sabine, VIRMANI, Arvind K, GAZDAR, Adi F, MINNA, John D

Volltext

High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three... von WISTUBA, I. I, BEHRENS, C, LERMAN, M. I, LAM, S, GAZDAR, A. F, MINNA, J. D, VIRMANI, A. K, MELE, G, MILCHGRUB, S, GIRARD, L, FONDON, J. W, GARNER, H. R, MCKAY, B, LATIF, F

Volltext

Localization of Bronchial Intraepithelial Neoplastic Lesions by Fluorescence Bronchoscopy von Lam, Stephen, Kennedy, Timothy, Unger, Michael, Miller, York E., Gelmont, David, Rusch, Valerie, Gipe, Bruce, Howard, David, LeRiche, Jean C., Coldman, Andrew, Gazdar, Adi F.

Volltext

Differential disruption of cell cycle pathways in small cell and non-small cell lung cancer von Coe, B P, Lockwood, W W, Girard, L, Chari, R, MacAulay, C, Lam, S, Gazdar, A F, Minna, J D, Lam, W L

Volltext

The relationship between aberrant methylation and survival in non-small-cell lung cancers von Toyooka, S, Suzuki, M, Maruyama, R, Toyooka, K O, Tsukuda, K, Fukuyama, Y, Iizasa, T, Aoe, M, Date, H, Fujisawa, T, Shimizu, N, Gazdar, A F

Volltext

Telomerase Activity in Human Breast Tumors von Hiyama, Eiso, Gollahon, Lauren, Kataoka, Tsuyoshi, Kuroi, Katsumasa, Yokoyama, Takashi, Gazdar, Adi F., Hiyama, Keiko, Piatyszek, Mieczyslaw A., Shay, Jerry W.

Volltext

Should we continue to use the term non-small-cell lung cancer? von Gazdar, A F

Volltext