Identification of apilimod as a first-in-class PIKfyve kinase inhibitor for treatment of B-cell non-Hodgkin lymphoma von Gayle, Sophia, Landrette, Sean, Beeharry, Neil, Conrad, Chris, Hernandez, Marylens, Beckett, Paul, Ferguson, Shawn M., Mandelkern, Talya, Zheng, Meiling, Xu, Tian, Rothberg, Jonathan, Lichenstein, Henri

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piggyBac Insertional Mutagenesis Screen Identifies a Role for Nuclear RHOA in Human ES Cell Differentiation von Gayle, Sophia, Pan, Yukun, Landrette, Sean, Xu, Tian

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LAM-003, a new drug for treatment of tyrosine kinase inhibitor–resistant FLT3-ITD–positive AML von Beeharry, Neil, Landrette, Sean, Gayle, Sophia, Hernandez, Marylens, Grotzke, Jeff E., Young, Peter R., Beckett, Paul, Zhang, Xuan, Carter, Bing Z., Andreeff, Michael, Halene, Stephanie, Xu, Tian, Rothberg, Jonathan, Lichenstein, Henri

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Loss of Drosophila melanogaster p21-activated kinase 3 suppresses defects in synapse structure and function caused by spastin mutations von Ozdowski, Emily F, Gayle, Sophia, Bao, Hong, Zhang, Bing, Sherwood, Nina T

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Tumor-selective, antigen-independent delivery of a pH sensitive peptide-topoisomerase inhibitor conjugate suppresses tumor growth without systemic toxicity von Gayle, Sophia, Aiello, Robert, Leelatian, Nalin, Beckta, Jason M, Bechtold, Jane, Bourassa, Patricia, Csengery, Johanna, Maguire, Robert J, Marshall, Dan, Sundaram, Ranjini K, Van Doorn, Jinny, Jones, Kelli, Moore, Hunter, Lopresti-Morrow, Lori, Paradis, Timothy, Tylaska, Laurie, Zhang, Qing, Visca, Hannah, Reshetnyak, Yana K, Andreev, Oleg A, Engelman, Donald M, Glazer, Peter M, Bindra, Ranjit S, Paralkar, Vishwas M

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TOP1-DNA Trapping by Exatecan and Combination Therapy with ATR Inhibitor von Jo, Ukhyun, Murai, Yasuhisa, Agama, Keli K, Sun, Yilun, Saha, Liton Kumar, Yang, Xi, Arakawa, Yasuhiro, Gayle, Sophia, Jones, Kelli, Paralkar, Vishwas, Sundaram, Ranjini K, Van Doorn, Jinny, Vasquez, Juan C, Bindra, Ranjit S, Choi, Woo Suk, Pommier, Yves

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Antigen-Independent Tumor Targeting by CBX-12 (Alphalex ™ –Exatecan) Induces Long-Term Antitumor Immunity von Gayle, Sophia, Paradis, Timothy, Jones, Kelli, Vasquez, Juan, Paralkar, Vishwas M

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Abstract P258: CBX-12 (alphalexTM-exatecan) sensitizes tumors to immune checkpoint blockade in an antigen agnostic manner by immune activation von Gayle, Sophia, Vasquez, Juan, Paradis, Timothy, Jones, Kelli, Sundaram, Ranjini, van Doorn, Jinny, Muthusamy, Viswanathan, Bindra, Ranjit S., Aiello, Robert J., Paralkar, Vishwas

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Abstract P047: A phase 1/2 trial of CBX-12, an alphalexTM peptide drug conjugate, in patients with advanced or metastatic refractory solid tumors von Tolcher, Anthony, Eder, Joseph Paul, Sommerhalder, David, Gayle, Sophia, Pearson, Paul, Chapman, Deb, DeCillis, Arthur P., Thomas, Anish, Meric-Bernstam, Funda

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Abstract B141: Evaluation of antigen-agnostic anti-tumor activity and immunological memory induced by CBX-15 (alphalexTM-MMAE) in the rat syngeneic breast cancer model von Gayle, Sophia, Paradis, Timothy, Zhang, Qing, Tylaska, Laurie, Hagen, Connor, Pasqualini, Theresa, Paralkar, Vishwas

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LAM-003, a Novel Oral Heat Shock Protein 90 Inhibitor for Treatment of Acute Myeloid Leukemia, Including Wild-Type and FMS-like Tyrosine Kinase 3 (FLT3)-Mutant Disease von Beeharry, Neil, Landrette, Sean, Grotzke, Jeff, Gayle, Sophia, Hernandez, Marylens, Halene, Stephanie, Young, Peter R, Miller, Langdon L, Xu, Tian, Rothberg, Jonathan, Lichenstein, Henri

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Abstract 6249: CBX-12: A low pH targeting alphalex™-exatecan conjugate for the treatment of solid tumors von Aiello, Robert J., Gayle, Sophia, Bechtold, Jane, Bourassa, Patricia, Csengery, Johanna, Deshpande, Ketaki, Jones, Kelli, Lopresti-Morrow, Lori, Maguire, Robert, Marshall, Dan, Moore, Hunter, Paradis, Timothy, Tylaska, Laurie, Zhang, Qing, Volkmann, Robert, Bindra, Ranjit S., Glazer, Peter M., Paralkar, Vishwas

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Abstract 6242: Development of alphalex™-toxin low pH targeting conjugates for the treatment of solid tumors von Gayle, Sophia, Aiello, Robert, Bechtold, Jane, Bourassa, Patricia, Csengery, Johanna, Deshpande, Ketaki, Jones, Kelli, Lopresti-Morrow, Lori, Maguire, Robert, Marshall, Dan, Moore, Hunter, Paradis, Timothy, Tylaska, Laurie, Zhang, Qing, Volkmann, Robert, Bindra, Ranjit S., Glazer, Peter M., Paralkar, Vishwas

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B-cell non-Hodgkin lymphoma: Selective vulnerability to PIKFYVE inhibition von Gayle, Sophia, Landrette, Sean, Beeharry, Neil, Conrad, Chris, Hernandez, Marylens, Beckett, Paul, Ferguson, Shawn M., Xu, Tian, Rothberg, Jonathan, Lichenstein, Henri

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Abstract 1764: Development of an alphalex™-auristatin low pH targeting conjugate for the treatment of solid tumors von Gayle, Sophia, Aiello, Robert, Bechtold, Jane, Bourassa, Patricia, Csengery, Johanna, Hagen, Connor, Howard, Katia, Jones, Kelli, Lopresti-Morrow, Lori, Maguire, Robert, Paradis, Timothy, Pasqualini, Theresa, Tweed, Joseph, Tylaska, Laurie, Zhang, Qing, Paralkar, Vishwas

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Correction to 'Tumor-selective, antigen-independent delivery of a pH sensitive peptide-topoisomerase inhibitor conjugate suppresses tumor growth without systemic toxicity' von Gayle, Sophia, Aiello, Robert, Leelatian, Nalin, Beckta, Jason M, Bechtold, Jane, Bourassa, Patricia, Csengery, Johanna, Maguire, Robert J, Marshall, Dan, Sundaram, Ranjini K, Van Doorn, Jinny, Jones, Kelli, Moore, Hunter, Lopresti-Morrow, Lori, Paradis, Timothy, Tylaska, Laurie, Zhang, Qing, Visca, Hannah, Reshetnyak, Yana K, Andreev, Oleg A, Engelman, Donald M, Glazer, Peter M, Bindra, Ranjit S, Paralkar, Vishwas M

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COMPOSITIONS COMPRISING PIKFYVE INHIBITORS AND METHODS RELATED TO INHIBITION OF RANK SIGNALING von GAYLE, Sophia, ROTHBERG, Jonathan, M, LICHENSTEIN, Henri

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COMPOSITIONS COMPRISING PIKFYVE INHIBITORS AND METHODS RELATED TO INHIBITION OF RANK SIGNALING von Lichenstein, Henri, Rothberg, Jonathan M, Gayle, Sophia

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Compositions comprising PIKfyve inhibitors and methods related to inhibition of rank signaling von Lichenstein, Henri, Rothberg, Jonathan M, Gayle, Sophia

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COMPOSITIONS COMPRISING PIKFYVE INHIBITORS AND METHODS RELATED TO INHIBITION OF RANK SIGNALING von GAYLE, SOPHIA, LICHENSTEIN, HENRI, ROTHBERG, JONATHAN M

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