Bayesian modeling and simulation to inform rare disease drug development early decision-making: Application to Duchenne muscular dystrophy von Lennie, Janelle L, Mondick, John T, Gastonguay, Marc R

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A Bayesian model selection approach to mediation analysis von Crouse, Wesley L, Keele, Gregory R, Gastonguay, Madeleine S, Churchill, Gary A, Valdar, William

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Midazolam Dose Optimization in Critically Ill Pediatric Patients With Acute Respiratory Failure: A Population Pharmacokinetic-Pharmacogenomic Study von Zuppa, Athena F., Conrado, Daniela J., Zane, Nicole R., Curley, Martha A. Q., Bradfield, Jonathan, Hakonarson, Hakon, Gastonguay, Madeleine S., Moorthy, Ganesh, Prodell, Janice, Gastonguay, Marc R.

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Morphine Dose Optimization in Critically Ill Pediatric Patients With Acute Respiratory Failure: A Population Pharmacokinetic-Pharmacogenomic Study von Zuppa, Athena F., Benitez, Giselle R., Zane, Nicole R., Curley, Martha A. Q., Bradfield, Jonathan, Hakonarson, Hakon, Gastonguay, Madeleine S., Moorthy, Ganesh, Prodell, Janice, Gastonguay, Marc R.

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Quantification of the Impact of Partition Coefficient Prediction Methods on Physiologically Based Pharmacokinetic Model Output Using a Standardized Tissue Composition von Utsey, Kiersten, Gastonguay, Madeleine S., Russell, Sean, Freling, Reed, Riggs, Matthew M., Elmokadem, Ahmed

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Vedolizumab exposure levels and clinical outcomes in ulcerative colitis: determining the potential for dose optimisation von Osterman, Mark T., Rosario, Maria, Lasch, Karen, Barocas, Morris, Wilbur, Jayson D., Dirks, Nathanael L., Gastonguay, Marc R.

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The trouble with triples: Examining the impact of measurement error in mediation analysis von Gastonguay, Madeleine S, Keele, Gregory R, Churchill, Gary A

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Population pharmacokinetics‐pharmacodynamics of vedolizumab in patients with ulcerative colitis and Crohn's disease von Rosario, M., Dirks, N. L., Gastonguay, M. R., Fasanmade, A. A., Wyant, T., Parikh, A., Sandborn, W. J., Feagan, B. G., Reinisch, W., Fox, I.

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Population Pharmacokinetics of Fluconazole in Young Infants von WADE, K. C, WU, D, GASTONGUAY, M. R, BARRETT, J. S, KAUFMAN, D. A, WARD, R. M, BENJAMIN, D. K, SULLIVAN, J. E, RAMEY, N, JAYARAMAN, B, HOPPU, K, ADAMSON, P. C

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Dexmedetomidine Pharmacology in Neonates and Infants After Open Heart Surgery von Su, Felice, Gastonguay, Marc R., Nicolson, Susan C., DiLiberto, MaryAnn, Ocampo-Pelland, Alanna, Zuppa, Athena F.

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The Pharmacokinetics and Pharmacodynamics of Buprenorphine in Neonatal Abstinence Syndrome von Moore, Jason N., Gastonguay, Marc R., Ng, Chee M., Adeniyi‐Jones, Susan C., Moody, David E., Fang, Wenfang B., Ehrlich, Michelle E., Kraft, Walter K.

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Research designs for proof-of-concept chronic pain clinical trials: IMMPACT recommendations von Gewandter, Jennifer S., Dworkin, Robert H., Turk, Dennis C., McDermott, Michael P., Baron, Ralf, Gastonguay, Marc R., Gilron, Ian, Katz, Nathaniel P., Mehta, Cyrus, Raja, Srinivasa N., Senn, Stephen, Taylor, Charles, Cowan, Penney, Desjardins, Paul, Dimitrova, Rozalina, Dionne, Raymond, Farrar, John T., Hewitt, David J., Iyengar, Smriti, Jay, Gary W., Kalso, Eija, Kerns, Robert D., Leff, Richard, Leong, Michael, Petersen, Karin L., Ravina, Bernard M., Rauschkolb, Christine, Rice, Andrew S.C., Rowbotham, Michael C., Sampaio, Cristina, Sindrup, Søren H., Stauffer, Joseph W., Steigerwald, Ilona, Stewart, Jonathan, Tobias, Jeffrey, Treede, Rolf-Detlef, Wallace, Mark, White, Richard E.

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A Pharmacokinetic Analysis of Tobramycin in Patients Less than Five Years of Age with Cystic Fibrosis: Assessment of Target Attainment with Extended-Interval Dosing through Simulat... von Downes, Kevin J, Grim, Austyn, Shanley, Laura, Rubenstein, Ronald C, Zuppa, Athena F, Gastonguay, Marc R

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SIGIRR genetic variants in premature infants with necrotizing enterocolitis von Sampath, Venkatesh, Menden, Heather, Helbling, Daniel, Li, Keguo, Gastonguay, Adam, Ramchandran, Ramani, Dimmock, David P

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Challenging the Norm: A Multidisciplinary Perspective on Intravenous to Subcutaneous Bridging Strategies for Biologics von Ait‐Oudhia, Sihem, Wang, Yow‐Ming, Dosne, Anne‐Gaelle, Roy, Amit, Jin, Jin Y., Shen, Jun, Kagan, Leonid, Musuamba, Flora T., Zhang, Lucia, Kijima, Shinichi, Gastonguay, Marc R., Ouellet, Daniele

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What are the experiences of colorectal cancer patients with biomarker testing in Canada?: a mixed methods study von Tongol, Elijah, Kang, Preet, Cheng, Vicki, Gastonguay, Louise, Beaudry, Felix E G, Servidio-Italiano, Filomena, De Vera, Mary A

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PCN47 INTEGRATION OF QUANTITATIVE SYSTEMS PHARMACOLOGY AND HEALTH ECONOMICS MODELS FOR DRUG DEVELOPMENT DECISION MAKING: APPLICATION TO TREATMENT OF SKELETAL RELATED EVENTS IN PATI... von Gastonguay, M., Riggs, M., Johnson, M.

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Pharmacometric dose optimization of buprenorphine in neonatal opioid withdrawal syndrome von Eudy‐Byrne, Rena, Zane, Nicole, Adeniyi‐Jones, Susan C., Gastonguay, Marc R., Ruiz‐Garcia, Ana, Kushal, Gagan, Kraft, Walter K.

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Splice Variants of SmgGDS Control Small GTPase Prenylation and Membrane Localization von Berg, Tracy J., Gastonguay, Adam J., Lorimer, Ellen L., Kuhnmuench, John R., Li, Rongshan, Fields, Alan P., Williams, Carol L.

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Virtual rheumatology appointments during the COVID-19 pandemic: an international survey of perspectives of patients with rheumatic diseases von Howren, Alyssa, Aviña-Zubieta, J. Antonio, Rebić, Nevena, Dau, Hallie, Gastonguay, Louise, Shojania, Kam, Davidson, Eileen, De Vera, Mary A.

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