SB‐224289–a novel selective (human) 5‐HT1B receptor antagonist with negative intrinsic activity von Selkirk, J V, Scott, C, Ho, M, Burton, M J, Watson, J, Gaster, L M, Collin, L, Jones, B J, Middlemiss, D N, Price, G W

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Serotonin 5-HT3 and 5-HT4 receptor antagonists von Gaster, Laramie M., King, Frank D.

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The effects of SB 204070, a highly potent and selective 5‐HT4 receptor antagonist, on guinea‐pig distal colon von Wardle, K.A., Ellis, E.S., Baxter, G.S., Kennett, G.A., Gaster, L.M., Sanger, G.J.

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SB-236057, a selective 5-HT1B receptor inverse agonist, blocks the 5-HT human terminal autoreceptor von MIDDLEMISS, D. N, GÖTHERT, M, SCHLICKER, E, SCOTT, C. M, SELKIRK, J. V, WATSON, J, GASTER, L. M, WYMAN, P, RILEY, G, PRICE, G. W

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Increased defaecation caused by 5-HT4 receptor activation in the mouse von BANNER, S. E, SMITH, M. I, BYWATER, D, GASTER, L. M, SANGER, G. J

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Synthesis of novel modified dipeptide inhibitors of human collagenase: .beta.-mercapto carboxylic acid derivatives von Beszant, Belle, Bird, John, Gaster, Laramie M, Harper, Gregory P, Hughes, Ian, Karran, Eric H, Markwell, Roger E, Miles-Williams, Anette J, Smith, Stephen A

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(1-Butyl-4-piperidinyl)methyl 8-amino-7-chloro-1,4-benzodioxane-5-carboxylate hydrochloride: a highly potent and selective 5-HT4 receptor antagonist derived from metoclopramide von Gaster, Laramie M, Jennings, Andrew J, Joiner, Graham F, King, Frank D, Mulholland, Keith R, Rahman, Shirley K, Starr, Susannah, Wyman, Paul A, Wardle, Kay A

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SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7 von Inman, Gareth J, Nicolás, Francisco J, Callahan, James F, Harling, John D, Gaster, Laramie M, Reith, Alastair D, Laping, Nicholas J, Hill, Caroline S

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Blockade of human atrial 5-HT4 receptors by SB 207710, a selective and high affinity 5-HT4 receptor antagonist von KAUMANN, A. J, GASTER, L. M, KING, F. D, BROWN, A. M

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Selective and functional 5‐hydroxytryptamine4 receptor antagonism by SB 207266 von Wardle, K.A., Bingham, S., Ellis, E.S., Gaster, L.M., Rushant, B., Smith, M.I., Sanger, G.J.

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The effect of SB-236057-A, a selective 5-HT1B receptor inverse agonist, on in vivo extracellular 5-HT levels in the freely-moving guinea-pig von Roberts, C, Hatcher, P, Hagan, J J, Austin, N E, Jeffrey, P, Wyman, P, Gaster, L M, Routledge, C, Middlemiss, D N

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(.+-.)-3-Amino-6-carboxamido-1,2,3,4-tetrahydrocarbazole: a conformationally restricted analog of 5-carboxamidotryptamine with selectivity for the serotonin 5-HT1D receptor von King, Frank D, Brown, Anthony M, Gaster, Laramie M, Kaumann, Alberto J, Medhurst, Andrew D, Parker, Stephen G, Parsons, Andrew A, Patch, Tracey L, Raval, Pravin

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N-[(1-Butyl-4-piperidinyl)methyl]-3,4- dihydro-2H-[1,3]oxazino[3,2-a]indole- 10-carboxamide hydrochloride: the first potent and selective 5-HT4 receptor antagonist amide with oral... von Gaster, Laramie M, Joiner, Graham F, King, Frank D, Wyman, Paul A, Sutton, Jonathan M, Bingham, Sharon, Ellis, Elizabeth S, Sanger, Gareth J, Wardle, Kay A

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SB‐224289–a novel selective (human) 5‐HT 1B receptor antagonist with negative intrinsic activity von Selkirk, J V, Scott, C, Ho, M, Burton, M J, Watson, J, Gaster, L M, Collin, L, Jones, B J, Middlemiss, D N, Price, G W

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The Selective 5-HT1B Receptor Inverse Agonist SB-224289, Potently Blocks Terminal 5-HT Autoreceptor Function both in Vitro and in Vivo von GASTER, L. M., HAM, P., JOINER, G. F., KING, F. D., MULHOLLAND, K. R., WYMAN, P. A., HAGAN, J. J., PRICE, G. W., ROBERTS, C., ROUTLEDGE, C., SELKIRK, J., SLADE, P. D., MIDDLEMISS, D. N.

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Biarylcarbamoylindolines Are Novel and Selective 5-HT2C Receptor Inverse Agonists:  Identification of 5-Methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluorometh... von Bromidge, Steven M, Dabbs, Steven, Davies, David T, Davies, Susannah, Duckworth, D. Malcolm, Forbes, Ian T, Gaster, Laramie M, Ham, Peter, Jones, Graham E, King, Frank D, Mulholland, Keith R, Saunders, Damian V, Wyman, Paul A, Blaney, Frank E, Clarke, Stephen E, Blackburn, Thomas P, Holland, Vicky, Kennett, Guy A, Lightowler, Sean, Middlemiss, Derek N, Trail, Brenda, Riley, Graham J, Wood, Martyn D

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The Selective 5-HT1B Receptor Inverse Agonist 1‘-Methyl-5-[[2‘-methyl-4‘- (5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydro- spiro[furo[2,3-f]indole-3,4‘-pi... von Gaster, Laramie M., Blaney, Frank E., Davies, Susannah, Duckworth, D. Malcolm, Ham, Peter, Jenkins, Sarah, Jennings, Andrew J., Joiner, Graham F., King, Frank D., Mulholland, Keith R., Wyman, Paul A., Hagan, Jim J., Hatcher, Jon, Jones, Brian J., Middlemiss, Derek N., Price, Gary W., Riley, Graham, Roberts, Claire, Routledge, Carol, Selkirk, Julie, Slade, Paula D.

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3,4-Dihydro-2H-benzoxazinones are 5-HT1A receptor antagonists with potent 5-HT reuptake inhibitory activity von ATKINSON, Peter J, BROMIDGE, Steven M, RAMI, Harshad K, RILEY, Graham J, SCOTT, Claire M, SHAW, Tracey E, STARR, Kathryn R, STEMP, Geoffrey, THEWLIS, Kevin M, THOMAS, David R, THOMPSON, Mervyn, VONG, Antonio K. K, DUXON, Mark S, WATSON, Jeannette M, GASTER, Laramie M, HADLEY, Michael S, HAMMOND, Beverley, JOHNSON, Christopher N, MIDDLEMISS, Derek N, NORTH, Stephanie E, PRICE, Gary W

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Biarylcarbamoylindolines are novel and selective 5-HT(2C) receptor inverse agonists: identification of 5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]- 5-pyridyl]carbamoyl]-6-trifluoromet... von Bromidge, S M, Dabbs, S, Davies, D T, Davies, S, Duckworth, D M, Forbes, I T, Gaster, L M, Ham, P, Jones, G E, King, F D, Mulholland, K R, Saunders, D V, Wyman, P A, Blaney, F E, Clarke, S E, Blackburn, T P, Holland, V, Kennett, G A, Lightowler, S, Middlemiss, D N, Trail, B, Riley, G J, Wood, M D

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Azabicyclic indole esters as potent 5-HT4 receptor antagonists von Wyman, P A, Gaster, L M, King, F D, Sutton, J M, Ellis, E S, Wardle, K A, Young, T J

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