Cas9–crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria von Gasiunas, Giedrius, Barrangou, Rodolphe, Horvath, Philippe, Siksnys, Virginijus

Volltext

The Streptococcus thermophilus CRISPR/Cas system provides immunity in Escherichia coli von Sapranauskas, Rimantas, Gasiunas, Giedrius, Fremaux, Christophe, Barrangou, Rodolphe, Horvath, Philippe, Siksnys, Virginijus

Volltext

A catalogue of biochemically diverse CRISPR-Cas9 orthologs von Gasiunas, Giedrius, Young, Joshua K., Karvelis, Tautvydas, Kazlauskas, Darius, Urbaitis, Tomas, Jasnauskaite, Monika, Grusyte, Mantvyda M., Paulraj, Sushmitha, Wang, Po-Hao, Hou, Zhenglin, Dooley, Shane K., Cigan, Mark, Alarcon, Clara, Chilcoat, N. Doane, Bigelyte, Greta, Curcuru, Jennifer L., Mabuchi, Megumu, Sun, Zhiyi, Fuchs, Ryan T., Schildkraut, Ezra, Weigele, Peter R., Jack, William E., Robb, G. Brett, Venclovas, Česlovas, Siksnys, Virginijus

Volltext

Rapid characterization of CRISPR-Cas9 protospacer adjacent motif sequence elements von Karvelis, Tautvydas, Gasiunas, Giedrius, Young, Joshua, Bigelyte, Greta, Silanskas, Arunas, Cigan, Mark, Siksnys, Virginijus

Volltext

Cas3 is a single-stranded DNA nuclease and ATP-dependent helicase in the CRISPR/Cas immune system von Sinkunas, Tomas, Gasiunas, Giedrius, Fremaux, Christophe, Barrangou, Rodolphe, Horvath, Philippe, Siksnys, Virginijus

Volltext

Molecular mechanisms of CRISPR-mediated microbial immunity von Gasiunas, Giedrius, Sinkunas, Tomas, Siksnys, Virginijus

Volltext

Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes von Szczelkun, Mark D., Tikhomirova, Maria S., Sinkunas, Tomas, Gasiunas, Giedrius, Karvelis, Tautvydas, Pschera, Patrizia, Siksnys, Virginijus, Seidel, Ralf

Volltext

In vitro reconstitution of Cascade-mediated CRISPR immunity in Streptococcus thermophilus von Sinkunas, Tomas, Gasiunas, Giedrius, Waghmare, Sakharam P, Dickman, Mark J, Barrangou, Rodolphe, Horvath, Philippe, Siksnys, Virginijus

Volltext

Harnessing the natural diversity and in vitro evolution of Cas9 to expand the genome editing toolbox von Karvelis, Tautvydas, Gasiunas, Giedrius, Siksnys, Virginijus

Volltext

Methods for decoding Cas9 protospacer adjacent motif (PAM) sequences: A brief overview von Karvelis, Tautvydas, Gasiunas, Giedrius, Siksnys, Virginijus

Volltext

5′ modifications to CRISPR–Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage von Mullally, Grace, van Aelst, Kara, Naqvi, Mohsin M, Diffin, Fiona M, Karvelis, Tautvydas, Gasiunas, Giedrius, Siksnys, Virginijus, Szczelkun, Mark D

Volltext

Discrimination of single-point mutations in unamplified genomic DNA via Cas9 immobilized on a graphene field-effect transistor von Balderston, Sarah, Taulbee, Jeffrey J., Celaya, Elizabeth, Fung, Kandace, Jiao, Amanda, Smith, Kasey, Hajian, Reza, Gasiunas, Giedrius, Kutanovas, Simonas, Kim, Daehwan, Parkinson, Jonathan, Dickerson, Kenneth, Ripoll, Juan-José, Peytavi, Regis, Lu, Hsiang-Wei, Barron, Francie, Goldsmith, Brett R., Collins, Philip G., Conboy, Irina M., Siksnys, Virginijus, Aran, Kiana

Volltext

Editorial: Current approaches to CRISPR/Cas9 delivery von Uludağ, Hasan, Aliabadi, Hamidreza Montazeri, Gasiunas, Giedrius

Volltext

RNA-dependent DNA endonuclease Cas9 of the CRISPR system: Holy Grail of genome editing? von Gasiunas, Giedrius, Siksnys, Virginijus

Volltext

Rewiring Cas9 to Target New PAM Sequences von Siksnys, Virginijus, Gasiunas, Giedrius

Volltext

Design of a CRISPR-Cas system to increase resistance of Bacillus subtilis to bacteriophage SPP1 von Jakutyte-Giraitiene, Lina, Gasiunas, Giedrius

Volltext

Genomic Characterization of Cyanophage vB_AphaS-CL131 Infecting Filamentous Diazotrophic Cyanobacterium Aphanizomenon flos-aquae Reveals Novel Insights into Virus-Bacterium Interac... von Šulčius, Sigitas, Šimoliūnas, Eugenijus, Alzbutas, Gediminas, Gasiūnas, Giedrius, Jauniškis, Vykintas, Kuznecova, Jolita, Miettinen, Sini, Nilsson, Emelie, Meškys, Rolandas, Roine, Elina, Paškauskas, Ričardas, Holmfeldt, Karin

Volltext

Structure of the DNA-Bound Spacer Capture Complex of a Type II CRISPR-Cas System von Wilkinson, Martin, Drabavicius, Gediminas, Silanskas, Arunas, Gasiunas, Giedrius, Siksnys, Virginijus, Wigley, Dale B.

Volltext

Streptococcus thermophilus CRISPR-Cas9 Systems Enable Specific Editing of the Human Genome von Müller, Maximilian, Lee, Ciaran M, Gasiunas, Giedrius, Davis, Timothy H, Cradick, Thomas J, Siksnys, Virginijus, Bao, Gang, Cathomen, Toni, Mussolino, Claudio

Volltext

crRNA and tracrRNA guide Cas9-mediated DNA interference in Streptococcus thermophilus von Karvelis, Tautvydas, Gasiunas, Giedrius, Miksys, Algirdas, Barrangou, Rodolphe, Horvath, Philippe, Siksnys, Virginijus

Volltext