The N550K/H Mutations in FGFR2 Confer Differential Resistance to PD173074, Dovitinib, and Ponatinib ATP-Competitive Inhibitors von Byron, Sara A, Chen, Huaibin, Wortmann, Andreas, Loch, David, Gartside, Michael G, Dehkhoda, Farhad, Blais, Steven P, Neubert, Thomas A, Mohammadi, Moosa, Pollock, Pamela M

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Frequent somatic mutations in MAP3K5 and MAP3K9 in metastatic melanoma identified by exome sequencing von Stark, Mitchell S, Woods, Susan L, Gartside, Michael G, Bonazzi, Vanessa F, Dutton-Regester, Ken, Aoude, Lauren G, Chow, Donald, Sereduk, Chris, Niemi, Natalie M, Tang, Nanyun, Ellis, Jonathan J, Reid, Jeffrey, Zismann, Victoria, Tyagi, Sonika, Muzny, Donna, Newsham, Irene, Wu, YuanQing, Palmer, Jane M, Pollak, Thomas, Youngkin, David, Brooks, Bradford R, Lanagan, Catherine, Schmidt, Christopher W, Kobe, Bostjan, MacKeigan, Jeffrey P, Yin, Hongwei, Brown, Kevin M, Gibbs, Richard, Trent, Jeffrey, Hayward, Nicholas K

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Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors von Marusiak, Anna A., Edwards, Zoe C., Hugo, Willy, Trotter, Eleanor W., Girotti, Maria R., Stephenson, Natalie L., Kong, Xiangju, Gartside, Michael G., Fawdar, Shameem, Hudson, Andrew, Breitwieser, Wolfgang, Hayward, Nicholas K., Marais, Richard, Lo, Roger S., Brognard, John

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Inhibition of Activated Fibroblast Growth Factor Receptor 2 in Endometrial Cancer Cells Induces Cell Death Despite PTEN Abrogation von BYRON, Sara A, GARTSIDE, Michael G, WELLENS, Candice L, MALLON, Mary A, KEENAN, Jack B, POWELL, Matthew A, GOODFELLOW, Paul J, POLLOCK, Pamela M

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Bcl‐2 inhibitors enhance FGFR inhibitor‐induced mitochondrial‐dependent cell death in FGFR2‐mutant endometrial cancer von Packer, Leisl M., Stehbens, Samantha J., Bonazzi, Vanessa F., Gunter, Jennifer H., Ju, Robert J., Ward, Micheal, Gartside, Michael G., Byron, Sara A., Pollock, Pamela M.

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Loss-of-Function Fibroblast Growth Factor Receptor-2 Mutations in Melanoma von Gartside, Michael G, Chen, Huaibin, Ibrahimi, Omar A, Byron, Sara A, Curtis, Amy V, Wellens, Candice L, Bengston, Ana, Yudt, Laura M, Eliseenkova, Anna V, Ma, Jinghong, Curtin, John A, Hyder, Pilar, Harper, Ursula L, Riedesel, Erica, Mann, Graham J, Trent, Jeffrey M, Bastian, Boris C, Meltzer, Paul S, Mohammadi, Moosa, Pollock, Pamela M

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Conditional Inactivation of the Men1 Gene Leads to Pancreatic and Pituitary Tumorigenesis but Does Not Affect Normal Development of These Tissues von Biondi, Christine A., Gartside, Michael G., Waring, Paul, Loffler, Kelly A., Stark, Mitchell S., Magnuson, Mark A., Kay, Graham F., Hayward, Nicholas K.

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FGFR2 mutations are rare across histologic subtypes of ovarian cancer von Byron, Sara A, Gartside, Michael G, Wellens, Candice L, Goodfellow, Paul J, Birrer, Michael J, Campbell, Ian G, Pollock, Pamela M

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POT1 loss-of-function variants predispose to familial melanoma von Robles-Espinoza, Carla Daniela, Harland, Mark, Ramsay, Andrew J, Aoude, Lauren G, Quesada, Víctor, Ding, Zhihao, Pooley, Karen A, Pritchard, Antonia L, Tiffen, Jessamy C, Petljak, Mia, Palmer, Jane M, Symmons, Judith, Johansson, Peter, Stark, Mitchell S, Gartside, Michael G, Snowden, Helen, Montgomery, Grant W, Martin, Nicholas G, Liu, Jimmy Z, Choi, Jiyeon, Makowski, Matthew, Brown, Kevin M, Dunning, Alison M, Keane, Thomas M, López-Otín, Carlos, Gruis, Nelleke A, Hayward, Nicholas K, Bishop, D Timothy, Newton-Bishop, Julia A, Adams, David J

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C-reactive protein is a prognostic biomarker in pancreatic ductal adenocarcinoma patients von Bonazzi, Vanessa F, Aoude, Lauren G, Brosda, Sandra, Bradford, Julia J, Lonie, James M, Loffler, Kelly A, Gartside, Michael G, Patel, Kalpana, Mukhopadhyay, Pamela, Keane, Colm, Gebski, Val, Kench, James G, Goldstein, David, Waddell, Nicola, Barbour, Andrew P

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Melanomas of unknown primary have a mutation profile consistent with cutaneous sun-exposed melanoma von Dutton-Regester, Ken, Kakavand, Hojabr, Aoude, Lauren G., Stark, Mitchell S., Gartside, Michael G., Johansson, Peter, O'Connor, Linda, Lanagan, Cathy, Tembe, Varsha, Pupo, Gulietta M., Haydu, Lauren E., Schmidt, Christopher W., Mann, Graham J., Thompson, John F., Scolyer, Richard A., Hayward, Nicholas K.

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Classification of esophageal adenocarcinoma into subgroups that are associated with patient survival using RNA-seq and immunohistochemistry von Sharma, Sowmya, Naeini, Marjan, Aoude, Lauren G, Bonazzi, Vanessa F, Gartside, Michael G, Loffler, Kelly A, Patel, Kalpana, Newell, Felicity, Lampe, Guy, Brosda, Sandra, Thomas, Janine, Smithers, Mark, Simes, John, Watson, David I., Pearson, John, Barbour, Andrew, Waddell, Nic

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Abstract C86: FGFR inhibition potentiates the effect of conventional chemotherapeutic agents in endometrial cancer cells von Byron, Sara A., Gartside, Michael G., Pollock, Pamela M.

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Abstract 20: POT1 mutations predispose to familial melanoma von Robles-Espinoza, Carla Daniela, Harland, Mark, Ramsay, Andrew J., Aoude, Lauren G., Quesada, Victor, Ding, Zhihao, Pooley, Karen A., Pritchard, Antonia L., Tiffen, Jessamy C., Petljak, Mia, Palmer, Jane M., Symmons, Judith, Johansson, Peter, Stark, Mitchell S., Gartside, Michael G., Snowden, Helen, Montgomery, Grant W., Martin, Nicholas G., Liu, Jimmy Z., Choi, Jiyeon, Makowski, Matthew, Brown, Kevin M., Dunning, Alison M., Keane, Thomas M., Lopez-Otin, Carlos, Gruis, Nelleke A., Hayward, Nicholas K., Bishop, D. Timothy, Newton-Bishop, Julia A., Adams, David J.

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The N550K/H Mutations in FGFR2 Confer Differential Resistance to PD173074, Dovitinib, and Ponatinib ATP-Competitive Inhibitors12 von Byron, Sara A, Chen, Huaibin, Wortmann, Andreas, Loch, David, Gartside, Michael G, Dehkhoda, Farhad, Blais, Steven P, Neubert, Thomas A, Mohammadi, Moosa, Pollock, Pamela M

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Evidence for persistent dysfunction of wild-type aldosterone synthase gene in glucocorticoid-treated familial hyperaldosteronism type I von Stowasser, Michael, Taylor, Wendy L, Gartside, Michael G, Tunny, Terry J, Gordon, Richard D

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Frequent somatic MAP3K5 and MAP3K9 mutations in metastatic melanoma identified by exome sequencing von Stark, Mitchell S, Woods, Susan L, Gartside, Michael G, Bonazzi, Vanessa F, Dutton-Regester, Ken, Aoude, Lauren G, Chow, Donald, Sereduk, Chris, Niemi, Natalie M, Tang, Nanyun, Ellis, Jonathan J, Reid, Jeffrey, Zismann, Victoria, Tyagi, Sonika, Muzny, Donna, Newsham, Irene, Wu, YuanQing, Palmer, Jane M, Pollak, Thomas, Youngkin, David, Brooks, Bradford R, Lanagan, Catherine, Schmidt, Christopher W, Kobe, Bostjan, MacKeigan, Jeffrey P, Yin, Hongwei, Brown, Kevin M, Gibbs, Richard, Trent, Jeffrey, Hayward, Nicholas K

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In familial hyperaldosteronism type I, hybrid gene-induced aldosterone production dominates that induced by Wild-type genes von STOWASSER, M, GARTSIDE, M. G, TAYLOR, W. L, TUNNY, T. J, GORDON, R. D

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In Familial Hyperaldosteronism Type I, Hybrid Gene-Induced Aldosterone Production Dominates That Induced by Wild-Type Genes1 von Stowasser, Michael, Gartside, Michael G, Taylor, Wendy L, Tunny, Terry J, Gordon, Richard D

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In Familial Hyperaldosteronism Type I, Hybrid Gene-Induced Aldosterone Production Dominates That Induced by Wild-Type Genes 1 von Stowasser, Michael, Gartside, Michael G., Taylor, Wendy L., Tunny, Terry J., Gordon, Richard D.

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