Vitamin C Antagonizes the Cytotoxic Effects of Antineoplastic Drugs von HEANEY, Mark L, GARDNER, Jeffrey R, KARASAVVAS, Nicos, GOLDE, David W, SCHEINBERG, David A, SMITH, Emily A, O'CONNOR, Owen A

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Clonal diversity predicts adverse outcome in chronic lymphocytic leukemia von Leeksma, Alexander C., Taylor, Justin, Wu, Bian, Gardner, Jeffrey R., He, Jie, Nahas, Michelle, Gonen, Mithat, Alemayehu, Wendimagegn G., te Raa, Doreen, Walther, Tatjana, Hüllein, Jennifer, Dietrich, Sascha, Claus, Rainer, de Boer, Fransien, de Heer, Koen, Dubois, Julie, Dampmann, Maria, Dürig, Jan, van Oers, Marinus H. J., Geisler, Christian H., Eldering, Eric, Levine, Ross L., Miller, Vincent, Mughal, Tariq, Lamanna, Nicole, Frattini, Mark G., Heaney, Mark L., Zelenetz, Andrew, Zenz, Thorsten, Abdel-Wahab, Omar, Kater, Arnon P.

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Synthesis and Preclinical Evaluation of QS-21 Variants Leading to Simplified Vaccine Adjuvants and Mechanistic Probes von Chea, Eric K, Fernández-Tejada, Alberto, Damani, Payal, Adams, Michelle M, Gardner, Jeffrey R, Livingston, Philip O, Ragupathi, Govind, Gin, David Y

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A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia von Mallikaratchy, Prabodhika R, Ruggiero, Alessandro, Gardner, Jeffrey R, Kuryavyi, Vitaly, Maguire, William F, Heaney, Mark L, McDevitt, Michael R, Patel, Dinshaw J, Scheinberg, David A

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Development of a minimal saponin vaccine adjuvant based on QS-21 von Fernández-Tejada, Alberto, Chea, Eric K., George, Constantine, Pillarsetty, NagaVaraKishore, Gardner, Jeffrey R., Livingston, Philip O., Ragupathi, Govind, Lewis, Jason S., Tan, Derek S., Gin, David Y.

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Targeting Bcl-2 family members with the BH3 mimetic AT-101 markedly enhances the therapeutic effects of chemotherapeutic agents in in vitro and in vivo models of B-cell lymphoma von Paoluzzi, Luca, Gonen, Mithat, Gardner, Jeffrey R., Mastrella, Jill, Yang, Dajun, Holmlund, Jon, Sorensen, Mel, Leopold, Lance, Manova, Katia, Marcucci, Guido, Heaney, Mark L., O’Connor, Owen A.

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The BH3-only mimetic ABT-737 synergizes the antineoplastic activity of proteasome inhibitors in lymphoid malignancies von Paoluzzi, Luca, Gonen, Mithat, Bhagat, Govind, Furman, Richard R., Gardner, Jeffrey R., Scotto, Luigi, Gueorguiev, Volodia D., Heaney, Mark L., Manova, Katia, O'Connor, Owen A.

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Design, synthesis, and immunologic evaluation of vaccine adjuvant conjugates based on QS-21 and tucaresol von Fernández-Tejada, Alberto, Chea, Eric K., George, Constantine, Gardner, Jeffrey R., Livingston, Philip O., Ragupathi, Govind, Tan, Derek S., Gin, David Y.

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Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis von Koppikar, Priya, Abdel-Wahab, Omar, Hedvat, Cyrus, Marubayashi, Sachie, Patel, Jay, Goel, Aviva, Kucine, Nicole, Gardner, Jeffrey R., Combs, Andrew P., Vaddi, Kris, Haley, Patrick J., Burn, Timothy C., Rupar, Mark, Bromberg, Jacqueline F., Heaney, Mark L., de Stanchina, Elisa, Fridman, Jordan S., Levine, Ross L.

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Human mitochondrial peptide deformylase, a new anticancer target of actinonin-based antibiotics von Lee, Mona D, She, Yuhong, Soskis, Michael J, Borella, Christopher P, Gardner, Jeffrey R, Hayes, Paula A, Dy, Benzon M, Heaney, Mark L, Philips, Mark R, Bornmann, William G, Sirotnak, Francis M, Scheinberg, David A

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The Warburg Effect Confers Adverse Outcome in Chronic Lymphocytic Leukemia von Gardner, Jeffrey R, Devlin, Sean M, Knapp, Kristina, Bauli, Francesco, Patel, Minal, Lamanna, Nicole, Frattini, Mark G, Brentjens, Renier, Maslak, Peter, Jurcic, Joseph G, Weiss, Mark A, Abdel-Wahab, Omar, Scheinberg, David A, Heaney, Mark L

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Soluble GM-CSF Receptor α Is Cytotoxic to Myeloid Cells in a Manner That Is Independent of GM-CSF Binding Inhibition von Gardner, Jeffrey R, Heaney, Mark Lawrence, Niu, Linghao

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Reply von Heaney, Mark L., Gardner, Jeffrey R., O'Connor, Owen A.

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Genomic Analysis of Serial Samples from CLL Patients Identifies Clonal Events Associated with Disease Progression von Gardner, Jeffrey R, Nahas, Michelle, He, Jie, Aumann, Shlomzion, Gonen, Mithat, Patel, Minal, Knapp, Kristina M., Palomba, Maria Lia, Yelensky, Roman, Donahue, Amy L, Otto, Geoff, Arcila, Maria, Lamanna, Nicole, Frattini, Mark G., Dogan, Ahmet, Park, Jae H, Lipson, Doron, Tallman, Martin S., Levine, Ross L., Stephens, Philip J., van den Brink, Marcel R.M., Heaney, Mark L, Miller, Vincent A., Zelenetz, Andrew D., Abdel-Wahab, Omar

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Extensive High-Depth Sequencing Of Longitudinal CLL Samples Identifies Frequent Mutations In MAP Kinase Signaling and Novel Mutations Activating Notch and Beta-Catenin von Gardner, Jeffrey R, Nahas, Michelle K., He, Jie, Patel, Minal, Knapp, Kristina M., Palomba, M. Lia, Yelensky, Roman, Donahue, Amy L, Otto, Geoff A., Arcila, Maria, Dogan, Ahmet, Park, Jae H, Zelenetz, Andrew D., Lipson, Doron, Tallman, Martin S., Levine, Ross L., Stephens, Philip J., van den Brink, Marcel R.M., Miller, Vincent A., Heaney, Mark L, Abdel-Wahab, Omar

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Elevated Mitochondrial Membrane Potential in CLL Cells Is Associated with a more aggressive Natural History von Gardner, Jeffrey R, Knapp, Kristina, Frattini, Mark G., Lamanna, Nicole, Brentjens, Renier, Jurcic, Joseph G, Maslak, Peter G., Berman, Ellin, Weiss, Mark, Scheinberg, David A., Heaney, Mark

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Aerobic Glycolysis Predicts Outcome in Early Chronic Lymphocytic Leukemia von Gardner, Jeffrey R, Devlin, Sean, Knapp, Kristina, Bauli, Francesco, Lamanna, Nicole, Frattini, Mark G., Brentjens, Renier J, Maslak, Peter G., Jurcic, Joseph G., Weiss, Mark, Scheinberg, David A., Heaney, Mark

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High Mitochondrial Membrane Potential Identifies Patients with Myeloproliferative Neoplasms with a More Aggressive Natural History von Gardner, Jeffrey R, Abdel-Wahab, Omar, Frattini, Mark, Jurcic, Joseph G, Knapp, Kristina, Rosenblat, Todd L., Soff, Gerald A., Levine, Ross, Heaney, Mark

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Dosage Regimen for the Treatment of Multiple Sclerosis with a S1P Receptor Modulator von GARDNER, Jeffrey R

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Malignant Cells in the Marrow and Blood of Patients with Hematopoietic Malignancies Have Higher Mitochondrial Membrane Potential as Measured with the Potentiometric Dye JC-1 von Gardner, Jeffrey R., Zhang, Rong H., Rose, Ruth, McKenzie, Sue, Maslak, Peter, Heaney, Mark L.

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