From discovery to licensure, the Adjuvant System story von Garçon, Nathalie, Di Pasquale, Alberta

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AS04, an Aluminum Salt- and TLR4 Agonist-Based Adjuvant System, Induces a Transient Localized Innate Immune Response Leading to Enhanced Adaptive Immunity von Didierlaurent, Arnaud M, Morel, Sandra, Lockman, Laurence, Giannini, Sandra L, Bisteau, Michel, Carlsen, Harald, Kielland, Anders, Vosters, Olivier, Vanderheyde, Nathalie, Schiavetti, Francesca, Larocque, Daniel, Van Mechelen, Marcelle, Garcon, Nathalie

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GlaxoSmithKline Adjuvant Systems in vaccines: concepts, achievements and perspectives von Garçon, Nathalie, Chomez, Patrick, Van Mechelen, Marcelle

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Enhancement of adaptive immunity by the human vaccine adjuvant AS01 depends on activated dendritic cells von Didierlaurent, Arnaud M, Collignon, Catherine, Bourguignon, Patricia, Wouters, Sandrine, Fierens, Kaat, Fochesato, Michel, Dendouga, Najoua, Langlet, Christelle, Malissen, Bernard, Lambrecht, Bart N, Garçon, Nathalie, Van Mechelen, Marcelle, Morel, Sandra

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Vaccine Adjuvants: from 1920 to 2015 and Beyond von Di Pasquale, Alberta, Preiss, Scott, Tavares Da Silva, Fernanda, Garçon, Nathalie

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Adjuvant System AS03 containing α-tocopherol modulates innate immune response and leads to improved adaptive immunity von Morel, Sandra, Didierlaurent, Arnaud, Bourguignon, Patricia, Delhaye, Sophie, Baras, Benoît, Jacob, Valérie, Planty, Camille, Elouahabi, Abdelatif, Harvengt, Pol, Carlsen, Harald, Kielland, Anders, Chomez, Patrick, Garçon, Nathalie, Van Mechelen, Marcelle

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Vaccine safety evaluation: Practical aspects in assessing benefits and risks von Di Pasquale, Alberta, Bonanni, Paolo, Garçon, Nathalie, Stanberry, Lawrence R, El-Hodhod, Mostafa, Tavares Da Silva, Fernanda

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Vaccine development: From concept to early clinical testing von Cunningham, Anthony L, Garçon, Nathalie, Leo, Oberdan, Friedland, Leonard R, Strugnell, Richard, Laupèze, Béatrice, Doherty, Mark, Stern, Peter

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Safety of AS03-adjuvanted influenza vaccines: A review of the evidence von Cohet, Catherine, van der Most, Robbert, Bauchau, Vincent, Bekkat-Berkani, Rafik, Doherty, T. Mark, Schuind, Anne, Tavares Da Silva, Fernanda, Rappuoli, Rino, Garçon, Nathalie, Innis, Bruce L.

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Vaccine provision: Delivering sustained & widespread use von Preiss, Scott, Garçon, Nathalie, Cunningham, Anthony L, Strugnell, Richard, Friedland, Leonard R

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Different Adjuvants Induce Common Innate Pathways That Are Associated with Enhanced Adaptive Responses against a Model Antigen in Humans von Burny, Wivine, Callegaro, Andrea, Bechtold, Viviane, Clement, Frédéric, Delhaye, Sophie, Fissette, Laurence, Janssens, Michel, Leroux-Roels, Geert, Marchant, Arnaud, van den Berg, Robert A, Garçon, Nathalie, van der Most, Robbert, Didierlaurent, Arnaud M

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The safety evaluation of adjuvants during vaccine development: The AS04 experience von Garçon, Nathalie, Segal, Lawrence, Tavares, Fernanda, Van Mechelen, Marcelle

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Cellular and molecular synergy in AS01-adjuvanted vaccines results in an early IFNγ response promoting vaccine immunogenicity von Coccia, Margherita, Collignon, Catherine, Hervé, Caroline, Chalon, Aurélie, Welsby, Iain, Detienne, Sophie, van Helden, Mary J., Dutta, Sheetij, Genito, Christopher J., Waters, Norman C., Van Deun, Katrijn, Smilde, Age K., van den Berg, Robert A., Franco, David, Bourguignon, Patricia, Morel, Sandra, Garçon, Nathalie, Lambrecht, Bart N., Goriely, Stanislas, van der Most, Robbert, Didierlaurent, Arnaud M.

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Antibody avidity, persistence, and response to antigen recall: comparison of vaccine adjuvants von Budroni, Sonia, Buricchi, Francesca, Cavallone, Andrea, Bourguignon, Patricia, Caubet, Magalie, Dewar, Vincent, D’Oro, Ugo, Finco, Oretta, Garçon, Nathalie, El Idrissi, Mohamed, Janssens, Michel, Leroux-Roels, Geert, Marchant, Arnaud, Schwarz, Tino, Van Damme, Pierre, Volpini, Gianfranco, van der Most, Robbert, Didierlaurent, Arnaud M., Burny, Wivine

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Impact of adjuvants on CD4+ T cell and B cell responses to a protein antigen vaccine: results from a phase II, randomized, multicenter trial von Leroux-Roels, Geert, Marchant, Arnaud, Levy, Jack, Van Damme, Pierre, Schwarz, Tino F, Horsmans, Yves, Jilg, Wolfgang, Kremsner, Peter G, Haelterman, Edwige, Clément, Frédéric, Gabor, Julian J, Esen, Meral, Hens, Annick, Carletti, Isabelle, Fissette, Laurence, Tavares Da Silva, Fernanda, Burny, Wivine, Janssens, Michel, Moris, Philippe, Didierlaurent, Arnaud M, Van Der Most, Robbert, Garçon, Nathalie, Van Belle, Pascale, Van Mechelen, Marcelle

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Vaccine Adjuvant Systems containing monophosphoryl lipid A and QS-21 induce strong humoral and cellular immune responses against hepatitis B surface antigen which persist for at le... von Leroux-Roels, Geert, Van Belle, Pascale, Vandepapeliere, Pierre, Horsmans, Yves, Janssens, Michel, Carletti, Isabelle, Garçon, Nathalie, Wettendorff, Martine, Van Mechelen, Marcelle

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Vaccine Adjuvant Systems containing monophosphoryl lipid A and QS21 induce strong and persistent humoral and T cell responses against hepatitis B surface antigen in healthy adult v... von Vandepapelière, Pierre, Horsmans, Yves, Moris, Philippe, Van Mechelen, Marcelle, Janssens, Michel, Koutsoukos, Marguerite, Van Belle, Pascale, Clement, Frédéric, Hanon, Emmanuel, Wettendorff, Martine, Garçon, Nathalie, Leroux-Roels, Geert

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Integrated clustering of multiple immune marker trajectories reveals different immunotypes in severely injured patients von Bodinier, Maxime, Peronnet, Estelle, Llitjos, Jean-François, Kreitmann, Louis, Brengel-Pesce, Karen, Rimmelé, Thomas, Fleurie, Aurore, Textoris, Julien, Venet, Fabienne, Maucort-Boulch, Delphine, Monneret, Guillaume

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Development of an AS04-Adjuvanted HPV Vaccine with the Adjuvant System Approach von Garçon, Nathalie, Morel, Sandra, Didierlaurent, Arnaud, Descamps, Dominique, Wettendorff, Martine, Van Mechelen, Marcelle

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Intramuscularly administered herpes zoster subunit vaccine has no effects on fertility, pre- and post-natal development in Sprague-Dawley rats von Segal, Lawrence, Thacker, Karen, Fochesato, Michel, Giordano, Giulia, Garçon, Nathalie, Destexhe, Eric

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