Identification and Characterization of a Novel Nuclear Protein Complex Involved in Nuclear Hormone Receptor-mediated Gene Regulation von Garapaty, Shivani, Xu, Chong-Feng, Trojer, Patrick, Mahajan, Muktar A., Neubert, Thomas A., Samuels, Herbert H.

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De novo peptide design and experimental validation of histone methyltransferase inhibitors von Smadbeck, James, Peterson, Meghan B, Zee, Barry M, Garapaty, Shivani, Mago, Aashna, Lee, Christina, Giannis, Athanassios, Trojer, Patrick, Garcia, Benjamin A, Floudas, Christodoulos A

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Proteoglycans mediate malaria sporozoite targeting to the liver von Pradel, Gabriele, Garapaty, Shivani, Frevert, Ute

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De novo peptide design and experimental validation of histone methyltransferase inhibitors von Smadbeck, James, Peterson, Meghan B, Zee, Barry M, Garapaty, Shivani, Mago, Aashna, Lee, Christina, Giannis, Athanassios, Trojer, Patrick, Garcia, Benjamin A, Floudas, Christodoulos A

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Components of the CCR4-NOT Complex Function as Nuclear Hormone Receptor Coactivators via Association with the NRC-interacting Factor NIF-1 von Garapaty, Shivani, Mahajan, Muktar A., Samuels, Herbert H.

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Discovery and Optimization of Tetramethylpiperidinyl Benzamides as Inhibitors of EZH2 von Nasveschuk, Christopher G, Gagnon, Alexandre, Garapaty-Rao, Shivani, Balasubramanian, Srividya, Campbell, Robert, Lee, Christina, Zhao, Feng, Bergeron, Louise, Cummings, Richard, Trojer, Patrick, Audia, James E, Albrecht, Brian K, Harmange, Jean-Christophe P

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Abstract 1128: Selective, novel, small molecule PRMT5 inhibitors for treatment of cancer von Sivanandhan, Dhanalakshmi, Rajagopal, Sridharan, M, Naveen Sadhu, Gajendran, Chandru, Vadivelu, Saravanan, Tamizharasan, Natarajan, Swamy, Indu N., Viswakarma, Santhosh, Siddiqui, Amir, wahid, Saif, Zainuddin, Mohammed, G, Rudresh, Daram, Prashanthi, Gosu, Ramchandraiah, Tiagaraj, Dinesh, Garapaty, Shivani, Nair, Sreekala, Kapoor, Namratha

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Abstract 5578: Small molecule modulators to understand the role of IDO1 and TDO2 in cancer von Garapaty, Shivani Rao, Sivanandhan, Dhanalakshmi, Seerapu, Guru Pavan Kumar, Naidu, Surendra, Chakelam, Shalini, Nagaraj, Pradeep, Das, Reshma, Vadivelu, Saravanan, Iyer, Pravin, Mulakala, Chandrika, Murugan, Kannan, Mondal, Somnath, Gautam, Anjali, Kandan, Saravanan, Thakur, Manish Kumar, Rajagopal, Sridharan, Rajagopal, Sriram

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Abstract 4856: Novel, small-molecule PRMT5 inhibitors for treatment of cancer von Sivanandhan, Dhanalakshmi, Garapaty, Shivani, Vadivelu, Saravanan, Seerapu, Guru Pavan Kumar, Das, Reshma, Kar, Ronodip, Singh, Anuj Kumar, Venkateshappa, Venkatesha Ashokkumar, Tamizharasan, Natarajan, Swamy, Indu N., Nagaraju, Nagendra, Kanagaraj, Subramaniyam, Sarkar, Sayanti, Tibhe, Jagadish D., G, Rudresh, Zainuddin, Mohd, Kandan, Saravanan, Rajagopal, Sridharan, Rajagopal, Sriram

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Abstract 5552: Novel, heterocyclic small molecule inhibitors of PD-1 and PD-L1 pathway von Dhanalakshmi, Sivanandhan, Garapaty, Shivani, Venkateshappa, Chandregowda, Seerapu, Guru Pavan, Das, Reshma, Nagaraj, Pradeep, Kar, Ronodip, Singh, Anuj Kumar, Venkatesubbiah, Venkatesha Ashokkumar, Putta, Ramakishore VP, Pendyala, Muralidhar, Lokesh, Girisha, Madaka, Hari, Thummuru, Harikrishna Reddy, AP, Shikas, Anchan, Prateeksha, Bhat, Prathima, G, Rudresha, Zainuddin, Mohd, V, Krishnakumar, Gosu, Ramachandraiah, Kristam, Rajendra, DA, Jeyaraj, Rajagopal, Sriram

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Abstract 5526: Inhibition of the histone methyl transferase EZH2 causes viability defects in multiple myeloma von Arora, Shilpi, Balasubramanian, Vidya, Williamson, Kaylyn, Gehling, Victor, Nasveschuk, Chris, Vaswani, Rishi, Busby, Jennifer, Garapaty, Shivani, Iyer, Priya, Zhao, Feng, Campbell, Robert, Cummings, Richard, Audia, Jim, Harmange, JC, Albrecht, Brian, Cook, Andrew, Dakin, Les, Normant, Emmanuel, Trojer, Patrick

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Abstract 4621: The histone methyltransferase EZH2 catalytic activity is required for cell growth in diffuse large B-cell lymphoma von Audia, James E., Trojer, Patrick, Garapaty, Shivani, Lan, Fei, Balasubramanian, Vidya, Chan, Eric, Hatton, Charles, Campbell, Robert, Cummings, Richard, Normant, Emmanuel, Bryant, Barbara, Albrecht, Brian, Harmange, Jean Christophe, Dakin, Les, Gehling, Victor, Nasveschuk, Chris, Vaswani, Rishi, Cook, Andrew

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Abstract PR09: EZH2 inhibitors reveal broad EZH2 dependencies in multiple myeloma von Arora, Shilpi, Williamson, Kaylyn, Balasubramanian, Srividya, Busby, Jennifer, Garapaty-Rao, Shivani, Hatton, Charlie, Sivanandhan, Dhanalakshmi, Bryant, Barbara, Normant, Emmanuel, Trojer, Patrick

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De Novo Peptide Design and Experimental Validation of Histone Methyltransferase Inhibitors: e90095 von Smadbeck, James, Peterson, Meghan B, Zee, Barry M, Garapaty, Shivani, Mago, Aashna, Lee, Christina, Giannis, Athanassios, Trojer, Patrick, Garcia, Benjamin A, Floudas, Christodoulos A

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HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS von Garapaty, Shivani, Sivanandhan, Dhanalakshmi, Nagaraju, Nagendra, Swamy, Indu N, Rajagopal, Sridharan, Samanta, Swapan Kumar, Vadivelu, Saravanan, Natarajan, Tamizharasan, Mohd, Zainuddin, Thakur, Manish Kumar, Burri, Raghunadha Reddy, Sarkar, Sayantani, Kanagaraj, Subramaniam

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HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS von BURRI, Raghunadha Reddy, KANAGARAJ, Subramaniam, SAMANTA, Swapan Kumar, NAGARAJU, Nagendra, MOHD, Zainuddin, RAJAGOPAL, Sridharan, SWAMY, Indu N, SARKAR, Sayantani, GARAPATY, Shivani, SIVANANDHAN, Dhanalakshmi, NATARAJAN, Tamizharasan, THAKUR, Manish Kumar, Hariprakash, VADIVELU, Saravanan

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HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS von VADIVELU, SARAVANAN, KANAGARAJ, SUBRAMANIAM, THAKUR, MANISH KUMAR, SWAMY, INDU N, MOHD, ZAINUDDIN, BURRI, RAGHUNADHA REDDY, NAGARAJU, NAGENDRA, NATARAJAN, TAMIZHARASAN, GARAPATY, SHIVANI, SIVANANDHAN, DHANALAKSHMI, RAJAGOPAL, SRIDHARAN, SARKAR, SAYANTANI, SAMANTA, SWAPAN KUMAR, HARIPRAKASH

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Kupffer and stellate cell proteoglycans mediate malaria sporozoite targeting to the liver von Pradel, Gabriele, Garapaty, Shivani, Frevert, Ute

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HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS von SIVANANDHAN Dhanalakshmi, KANAGARAJ Subramaniam, MOHD Zainuddin, NATARAJAN Tamizharasan, SWAMY Indu N, THAKUR Manish Kumar, GARAPATY Shivani, BURRI Raghunadha Reddy, VADIVELU Saravanan, SAMANTA Swapan Kumar, RAJAGOPAL Sridharan, Hariprakash, NAGARAJU Nagendra, SARKAR Sayantani

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HETEROCYCLIC COMPOUNDS AS PRMT5 INHIBITORS von VADIVELU, SARAVANAN, KANAGARAJ, SUBRAMANIAM, SAMANTA, SWAPAN, KUMAR, SWAMY, INDU N, MOHD, ZAINUDDIN, BURRI, RAGHUNADHA, REDDY, NAGARAJU, NAGENDRA, NATARAJAN, TAMIZHARASAN, GARAPATY, SHIVANI, SIVANANDHAN, DHANALAKSHMI, RAJAGOPAL, SRIDHARAN, SARKAR, SAYANTANI, THAKUR, MANISH, KUMAR, HARIPRAKASH

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