Cancer Cell-Autonomous TRAIL-R Signaling Promotes KRAS-Driven Cancer Progression, Invasion, and Metastasis von von Karstedt, Silvia, Conti, Annalisa, Nobis, Max, Montinaro, Antonella, Hartwig, Torsten, Lemke, Johannes, Legler, Karen, Annewanter, Franka, Campbell, Andrew D., Taraborrelli, Lucia, Grosse-Wilde, Anne, Coy, Johannes F., El-Bahrawy, Mona A., Bergmann, Frank, Koschny, Ronald, Werner, Jens, Ganten, Tom M., Schweiger, Thomas, Hoetzenecker, Konrad, Kenessey, Istvan, Hegedüs, Balazs, Bergmann, Michael, Hauser, Charlotte, Egberts, Jan-Hendrik, Becker, Thomas, Röcken, Christoph, Kalthoff, Holger, Trauzold, Anna, Anderson, Kurt I., Sansom, Owen J., Walczak, Henning

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Sorafenib in Patients with Hepatocellular Carcinoma-Results of the Observational INSIGHT Study von Ganten, Tom M, Stauber, Rudolf E, Schott, Eckardt, Malfertheiner, Peter, Buder, Robert, Galle, Peter R, Göhler, Thomas, Walther, Matthias, Koschny, Ronald, Gerken, Guido

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Resminostat plus sorafenib as second-line therapy of advanced hepatocellular carcinoma – The SHELTER study von Bitzer, Michael, Horger, Marius, Giannini, Edoardo G, Ganten, Tom M, Wörns, Marcus A, Siveke, Jens T, Dollinger, Matthias M, Gerken, Guido, Scheulen, Max E, Wege, Henning, Zagonel, Vittorina, Cillo, Umberto, Trevisani, Franco, Santoro, Armando, Montesarchio, Vincenzo, Malek, Nisar P, Holzapfel, Julia, Herz, Thomas, Ammendola, Astrid S, Pegoraro, Stefano, Hauns, Bernhard, Mais, Anna, Lauer, Ulrich M, Henning, Stefan W, Hentsch, Bernd

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The promise of TRAIL : potential and risks of a novel anticancer therapy von KOSCHNY, Ronald, WALCZAK, Henning, GANTEN, Tom M

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Yes and PI3K Bind CD95 to Signal Invasion of Glioblastoma von Kleber, Susanne, Sancho-Martinez, Ignacio, Wiestler, Benedict, Beisel, Alexandra, Gieffers, Christian, Hill, Oliver, Thiemann, Meinolf, Mueller, Wolf, Sykora, Jaromir, Kuhn, Andreas, Schreglmann, Nina, Letellier, Elisabeth, Zuliani, Cecilia, Klussmann, Stefan, Teodorczyk, Marcin, Gröne, Hermann-Josef, Ganten, Tom M., Sültmann, Holger, Tüttenberg, Jochen, von Deimling, Andreas, Regnier-Vigouroux, Anne, Herold-Mende, Christel, Martin-Villalba, Ana

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Diarrhea Is a Positive Outcome Predictor for Sorafenib Treatment of Advanced Hepatocellular Carcinoma von Koschny, Ronald, Gotthardt, Daniel, Koehler, Christiane, Jaeger, Dirk, Stremmel, Wolfgang, Ganten, Tom M.

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Preclinical Differentiation between Apparently Safe and Potentially Hepatotoxic Applications of TRAIL Either Alone or in Combination with Chemotherapeutic Drugs von GANTEN, Tom M, KOSCHNY, Ronald, SYKORA, Jaromir, SCHULZE-BERGKAMEN, Henning, BÜCHLER, Peter, HAAS, Tobias L, SCHADER, Manuela B, UNTERGASSER, Andreas, STREMMEL, Wolfgang, WALCZAK, Henning

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Bortezomib Sensitizes Primary Human Astrocytoma Cells of WHO Grades I to IV for Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Induced Apoptosis von KOSCHNY, Ronald, HOLLAND, Heidrun, WALCZAK, Henning, SYKORA, Jaromir, HAAS, Tobias L, SPRICK, Martin R, GANTEN, Tom M, KRUPP, Wolfgang, BAUER, Manfred, AHNERT, Peter, MEIXENSBERGER, Jürgen

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mTOR Inhibition Is Most Beneficial After Liver Transplantation for Hepatocellular Carcinoma in Patients With Active Tumors von Schnitzbauer, Andreas A., Filmann, Natalie, Adam, René, Bachellier, Philippe, Bechstein, Wolf O., Becker, Thomas, Bhoori, Sherrie, Bilbao, Itxarone, Brockmann, Jens, Burra, Patrizia, Chazoullières, Olivier, Cillo, Umberto, Colledan, Michele, Duvoux, Christoph, Ganten, Tom M., Gugenheim, Jean, Heise, Michael, van Hoek, Bart, Jamieson, Neville, de Jong, Koert P., Klein, Christian G., Klempnauer, Jürgen, Kneteman, Norman, Lerut, Jan, Mäkisalo, Heikki, Mazzaferro, Vincenzo, Mirza, Darius F., Nadalin, Silvio, Neuhaus, Peter, Pageaux, George-Philippe, Pinna, Antonio D., Pirenne, Jaques, Pratschke, Johann, Powel, James, Rentsch, Markus, Rizell, Magnus, Rossi, Giorgio, Rostaing, Lionel, Roy, André, Scholz, Tim, Settmacher, Utz, Soliman, Thomas, Strasser, Simone, Söderdahl, Gunnar, Troisi, Roberto I., Turrión, Victor Sánchez, Schlitt, Hans J., Geissler, Edward K.

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Sirolimus Use in Liver Transplant Recipients With Hepatocellular Carcinoma: A Randomized, Multicenter, Open-Label Phase 3 Trial von Geissler, Edward K, Schnitzbauer, Andreas A, Zülke, Carl, Lamby, Philipp E, Proneth, Andrea, Duvoux, Christophe, Burra, Patrizia, Jauch, Karl-Walter, Rentsch, Markus, Ganten, Tom M, Schmidt, Jan, Settmacher, Utz, Heise, Michael, Rossi, Giorgio, Cillo, Umberto, Kneteman, Norman, Adam, René, van Hoek, Bart, Bachellier, Philippe, Wolf, Philippe, Rostaing, Lionel, Bechstein, Wolf O, Rizell, Magnus, Powell, James, Hidalgo, Ernest, Gugenheim, Jean, Wolters, Heiner, Brockmann, Jens, Roy, André, Mutzbauer, Ingrid, Schlitt, Angela, Beckebaum, Susanne, Graeb, Christian, Nadalin, Silvio, Valente, Umberto, Turrión, Victor Sánchez, Jamieson, Neville, Scholz, Tim, Colledan, Michele, Fändrich, Fred, Becker, Thomas, Söderdahl, Gunnar, Chazouillères, Olivier, Mäkisalo, Heikki, Pageaux, Georges-Philippe, Steininger, Rudolf, Soliman, Thomas, de Jong, Koert P, Pirenne, Jacques, Margreiter, Raimund, Pratschke, Johann, Pinna, Antonio D, Hauss, Johann, Schreiber, Stefan, Strasser, Simone, Klempnauer, Jürgen, Troisi, Roberto I, Bhoori, Sherrie, Lerut, Jan, Bilbao, Itxarone, Klein, Christian G, Königsrainer, Alfred, Mirza, Darius F, Otto, Gerd, Mazzaferro, Vincenzo, Neuhaus, Peter, Schlitt, Hans J

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Bortezomib Sensitizes Primary Meningioma Cells to TRAIL-Induced Apoptosis by Enhancing Formation of the Death-Inducing Signaling Complex von Koschny, Ronald, Boehm, Christina, Sprick, Martin R, Haas, Tobias L, Holland, Heidrun, Xu, Li-Xin, Krupp, Wolfgang, Mueller, Wolf C, Bauer, Manfred, Koschny, Thomas, Keller, Marius, Sinn, Peter, Meixensberger, Juergen, Walczak, Henning, Ganten, Tom M

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Quantitative therapy response assessment by volumetric iodine-uptake measurement: Initial experience in patients with advanced hepatocellular carcinoma treated with sorafenib von Dai, Xu, Schlemmer, Heinz-Peter, Schmidt, Bernhard, Höh, Karolin, Xu, Ke, Ganten, Tom M, Ganten, Maria-Katharina

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Liver allocation: urgency of need or prospect of success? Ethical considerations von Bobbert, Monika, Ganten, Tom M.

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CYP3A activity in severe liver cirrhosis correlates with Child–Pugh and model for end‐stage liver disease (MELD) scores von Albarmawi, Albader, Czock, David, Gauss, Annika, Ehehalt, Robert, Lorenzo Bermejo, Justo, Burhenne, Jürgen, Ganten, Tom M., Sauer, Peter, Haefeli, Walter E.

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TRAIL/bortezomib cotreatment is potentially hepatotoxic but induces cancer‐specific apoptosis within a therapeutic window von Koschny, Ronald, Ganten, Tom M., Sykora, Jaromir, Haas, Tobias L., Sprick, Martin R., Kolb, Armin, Stremmel, Wolfgang, Walczak, Henning

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Pancreatic Atrophy in Hepatocellular Carcinoma Patients Receiving Long-Term Treatment with Sorafenib von Ganten, Maria-Katharina, Schuessler, Max, Bruckner, Thomas, Ganten, Tom M., Koschny, Ronald

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Prognostic significance of tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) receptor expression in patients with breast cancer von Ganten, Tom M., Sykora, Jaromir, Koschny, Ronald, Batke, Emanuela, Aulmann, Sebastian, Mansmann, Ulrich, Stremmel, Wolfgang, Sinn, Hans-Peter, Walczak, Henning

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Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B von Esser‐Nobis, Katharina, Romero‐Brey, Inés, Ganten, Tom M., Gouttenoire, Jérôme, Harak, Christian, Klein, Rahel, Schemmer, Peter, Binder, Marco, Schnitzler, Paul, Moradpour, Darius, Bartenschlager, Ralf, Polyak, Stephen J., Stremmel, Wolfgang, Penin, François, Eisenbach, Christoph, Lohmann, Volker

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Proteasome inhibition sensitizes hepatocellular carcinoma cells, but not human hepatocytes, to TRAIL von GANTEN, Tom M, KOSCHNY, Ronald, HAAS, Tobias L, SYKORA, Jaromir, LI-WEBER, Min, HERZER, Kerstin, WALCZAK, Henning

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Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma von Koschny, Ronald, Brost, Sylvia, Hinz, Ulf, Sykora, Jaromir, Batke, Emanuela M, Singer, Stephan, Breuhahn, Kai, Stremmel, Wolfgang, Walczak, Henning, Schemmer, Peter, Schirmacher, Peter, Ganten, Tom M

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