Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade von Benci, Joseph L., Xu, Bihui, Qiu, Yu, Wu, Tony J., Dada, Hannah, Twyman-Saint Victor, Christina, Cucolo, Lisa, Lee, David S.M., Pauken, Kristen E., Huang, Alexander C., Gangadhar, Tara C., Amaravadi, Ravi K., Schuchter, Lynn M., Feldman, Michael D., Ishwaran, Hemant, Vonderheide, Robert H., Maity, Amit, Wherry, E. John, Minn, Andy J.

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Programmed Death-Ligand 1 Expression and Response to the Anti-Programmed Death 1 Antibody Pembrolizumab in Melanoma von Daud, Adil I, Wolchok, Jedd D, Robert, Caroline, Hwu, Wen-Jen, Weber, Jeffrey S, Ribas, Antoni, Hodi, F Stephen, Joshua, Anthony M, Kefford, Richard, Hersey, Peter, Joseph, Richard, Gangadhar, Tara C, Dronca, Roxana, Patnaik, Amita, Zarour, Hassane, Roach, Charlotte, Toland, Grant, Lunceford, Jared K, Li, Xiaoyun Nicole, Emancipator, Kenneth, Dolled-Filhart, Marisa, Kang, S Peter, Ebbinghaus, Scot, Hamid, Omid

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Radiation and dual checkpoint blockade activate non-redundant immune mechanisms in cancer von Twyman-Saint Victor, Christina, Rech, Andrew J., Maity, Amit, Rengan, Ramesh, Pauken, Kristen E., Stelekati, Erietta, Benci, Joseph L., Xu, Bihui, Dada, Hannah, Odorizzi, Pamela M., Herati, Ramin S., Mansfield, Kathleen D., Patsch, Dana, Amaravadi, Ravi K., Schuchter, Lynn M., Ishwaran, Hemant, Mick, Rosemarie, Pryma, Daniel A., Xu, Xiaowei, Feldman, Michael D., Gangadhar, Tara C., Hahn, Stephen M., Wherry, E. John, Vonderheide, Robert H., Minn, Andy J.

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Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial von Robert, Caroline, Prof, Ribas, Antoni, Prof, Wolchok, Jedd D, Prof, Hodi, F Stephen, MD, Hamid, Omid, MD, Kefford, Richard, Prof, Weber, Jeffrey S, Prof, Joshua, Anthony M, PhD, Hwu, Wen-Jen, Prof, Gangadhar, Tara C, MD, Patnaik, Amita, MD, Dronca, Roxana, MD, Zarour, Hassane, Prof, Joseph, Richard W, MD, Boasberg, Peter, MD, Chmielowski, Bartosz, MD, Mateus, Christine, MD, Postow, Michael A, MD, Gergich, Kevin, MA, Elassaiss-Schaap, Jeroen, PhD, Li, Xiaoyun Nicole, PhD, Iannone, Robert, MD, Ebbinghaus, Scot W, MD, Kang, S Peter, MD, Daud, Adil, Prof

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The efficacy of anti‐PD‐1 agents in acral and mucosal melanoma von Shoushtari, Alexander N., Munhoz, Rodrigo R., Kuk, Deborah, Ott, Patrick A., Johnson, Douglas B., Tsai, Katy K., Rapisuwon, Suthee, Eroglu, Zeynep, Sullivan, Ryan J., Luke, Jason J., Gangadhar, Tara C., Salama, April K. S., Clark, Varina, Burias, Clare, Puzanov, Igor, Atkins, Michael B., Algazi, Alain P., Ribas, Antoni, Wolchok, Jedd D., Postow, Michael A.

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BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth von Wang, Tao, Xiao, Min, Ge, Yingbin, Krepler, Clemens, Belser, Eric, Lopez-Coral, Alfonso, Xu, Xiaowei, Zhang, Gao, Azuma, Rikka, Liu, Qin, Liu, Rui, Li, Ling, Amaravadi, Ravi K, Xu, Wei, Karakousis, Giorgos, Gangadhar, Tara C, Schuchter, Lynn M, Lieu, Melissa, Khare, Sanika, Halloran, Molly B, Herlyn, Meenhard, Kaufman, Russel E

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Long-term outcomes of a phase I study of agonist CD40 antibody and CTLA-4 blockade in patients with metastatic melanoma von Bajor, David L., Mick, Rosemarie, Riese, Matthew J., Huang, Alex C., Sullivan, Brendan, Richman, Lee P., Torigian, Drew A., George, Sangeeth M., Stelekati, Erietta, Chen, Fang, Melenhorst, J. Joseph, Lacey, Simon F., Xu, Xiaowei, Wherry, E. John, Gangadhar, Tara C., Amaravadi, Ravi K., Schuchter, Lynn M., Vonderheide, Robert H.

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Cutaneous autoimmune effects in the setting of therapeutic immune checkpoint inhibition for metastatic melanoma von Mochel, Mark C., Ming, Michael E., Imadojemu, Sotonye, Gangadhar, Tara C., Schuchter, Lynn M., Elenitsas, Rosalie, Payne, Aimee S., Chu, Emily Y.

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Durable Complete Response After Discontinuation of Pembrolizumab in Patients With Metastatic Melanoma von Robert, Caroline, Ribas, Antoni, Hamid, Omid, Daud, Adil, Wolchok, Jedd D, Joshua, Anthony M, Hwu, Wen-Jen, Weber, Jeffrey S, Gangadhar, Tara C, Joseph, Richard W, Dronca, Roxana, Patnaik, Amita, Zarour, Hassane, Kefford, Richard, Hersey, Peter, Zhang, Jin, Anderson, James, Diede, Scott J, Ebbinghaus, Scot, Hodi, F Stephen

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Feasibility of monitoring advanced melanoma patients using cell‐free DNA from plasma von Gangadhar, Tara C., Savitch, Samantha L., Yee, Stephanie S., Xu, Wei, Huang, Alexander C., Harmon, Shannon, Lieberman, David B., Soucier, Devon, Fan, Ryan, Black, Taylor A., Morrissette, Jennifer J. D., Salathia, Neeraj, Waters, Jill, Zhang, Shile, Toung, Jonathan, Hummelen, Paul, Fan, Jian‐Bing, Xu, Xiaowei, Amaravadi, Ravi K., Schuchter, Lynn M., Karakousis, Giorgos C., Hwang, Wei‐Ting, Carpenter, Erica L.

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Evaluation of Immune-Related Response Criteria and RECIST v1.1 in Patients With Advanced Melanoma Treated With Pembrolizumab von Hodi, F Stephen, Hwu, Wen-Jen, Kefford, Richard, Weber, Jeffrey S, Daud, Adil, Hamid, Omid, Patnaik, Amita, Ribas, Antoni, Robert, Caroline, Gangadhar, Tara C, Joshua, Anthony M, Hersey, Peter, Dronca, Roxana, Joseph, Richard, Hille, Darcy, Xue, Dahai, Li, Xiaoyun Nicole, Kang, S Peter, Ebbinghaus, Scot, Perrone, Andrea, Wolchok, Jedd D

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T-cell invigoration to tumour burden ratio associated with anti-PD-1 response von Huang, Alexander C., Postow, Michael A., Orlowski, Robert J., Mick, Rosemarie, Bengsch, Bertram, Manne, Sasikanth, Xu, Wei, Harmon, Shannon, Giles, Josephine R., Wenz, Brandon, Adamow, Matthew, Kuk, Deborah, Panageas, Katherine S., Carrera, Cristina, Wong, Phillip, Quagliarello, Felix, Wubbenhorst, Bradley, D’Andrea, Kurt, Pauken, Kristen E., Herati, Ramin S., Staupe, Ryan P., Schenkel, Jason M., McGettigan, Suzanne, Kothari, Shawn, George, Sangeeth M., Vonderheide, Robert H., Amaravadi, Ravi K., Karakousis, Giorgos C., Schuchter, Lynn M., Xu, Xiaowei, Nathanson, Katherine L., Wolchok, Jedd D., Gangadhar, Tara C., Wherry, E. John

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Association of Pembrolizumab With Tumor Response and Survival Among Patients With Advanced Melanoma von Ribas, Antoni, Hamid, Omid, Daud, Adil, Hodi, F. Stephen, Wolchok, Jedd D, Kefford, Richard, Joshua, Anthony M, Patnaik, Amita, Hwu, Wen-Jen, Weber, Jeffrey S, Gangadhar, Tara C, Hersey, Peter, Dronca, Roxana, Joseph, Richard W, Zarour, Hassane, Chmielowski, Bartosz, Lawrence, Donald P, Algazi, Alain, Rizvi, Naiyer A, Hoffner, Brianna, Mateus, Christine, Gergich, Kevin, Lindia, Jill A, Giannotti, Maxine, Li, Xiaoyun Nicole, Ebbinghaus, Scot, Kang, S. Peter, Robert, Caroline

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Baseline Tumor Size Is an Independent Prognostic Factor for Overall Survival in Patients with Melanoma Treated with Pembrolizumab von Joseph, Richard W, Elassaiss-Schaap, Jeroen, Kefford, Richard, Hwu, Wen-Jen, Wolchok, Jedd D, Joshua, Anthony M, Ribas, Antoni, Hodi, F Stephen, Hamid, Omid, Robert, Caroline, Daud, Adil, Dronca, Roxana, Hersey, Peter, Weber, Jeffrey S, Patnaik, Amita, de Alwis, Dinesh P, Perrone, Andrea, Zhang, Jin, Kang, S Peter, Ebbinghaus, Scot, Anderson, Keaven M, Gangadhar, Tara C

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Results from an Integrated Safety Analysis of Urelumab, an Agonist Anti-CD137 Monoclonal Antibody von Segal, Neil H, Logan, Theodore F, Hodi, F Stephen, McDermott, David, Melero, Ignacio, Hamid, Omid, Schmidt, Henrik, Robert, Caroline, Chiarion-Sileni, Vanna, Ascierto, Paolo A, Maio, Michele, Urba, Walter J, Gangadhar, Tara C, Suryawanshi, Satyendra, Neely, Jaclyn, Jure-Kunkel, Maria, Krishnan, Suba, Kohrt, Holbrook, Sznol, Mario, Levy, Ronald

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Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma von Hamid, Omid, Robert, Caroline, Daud, Adil, Hodi, F. Stephen, Hwu, Wen-Jen, Kefford, Richard, Wolchok, Jedd D, Hersey, Peter, Joseph, Richard W, Weber, Jeffrey S, Dronca, Roxana, Gangadhar, Tara C, Patnaik, Amita, Zarour, Hassane, Joshua, Anthony M, Gergich, Kevin, Elassaiss-Schaap, Jeroen, Algazi, Alain, Mateus, Christine, Boasberg, Peter, Tumeh, Paul C, Chmielowski, Bartosz, Ebbinghaus, Scot W, Li, Xiaoyun Nicole, Kang, S. Peter, Ribas, Antoni

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Final analysis of a randomised trial comparing pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory advanced melanoma von Hamid, Omid, Puzanov, Igor, Dummer, Reinhard, Schachter, Jacob, Daud, Adil, Schadendorf, Dirk, Blank, Christian, Cranmer, Lee D., Robert, Caroline, Pavlick, Anna C., Gonzalez, Rene, Hodi, F. Stephen, Ascierto, Paolo A., Salama, April K.S., Margolin, Kim A., Gangadhar, Tara C., Wei, Ziwen, Ebbinghaus, Scot, Ibrahim, Nageatte, Ribas, Antoni

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Long-term safety of pembrolizumab monotherapy and relationship with clinical outcome: A landmark analysis in patients with advanced melanoma von Robert, Caroline, Hwu, Wen-Jen, Hamid, Omid, Ribas, Antoni, Weber, Jeffrey S., Daud, Adil I., Hodi, F. Stephen, Wolchok, Jedd D., Mitchell, Tara C., Hersey, Peter, Dronca, Roxana, Joseph, Richard W., Boutros, Celine, Min, Le, Long, Georgina V., Schachter, Jacob, Puzanov, Igor, Dummer, Reinhard, Lin, Jianxin, Ibrahim, Nageatte, Diede, Scott J., Carlino, Matteo S., Joshua, Anthony M.

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Targeting mitochondrial biogenesis to overcome drug resistance to MAPK inhibitors von Zhang, Gao, Frederick, Dennie T, Wu, Lawrence, Wei, Zhi, Krepler, Clemens, Srinivasan, Satish, Chae, Young Chan, Xu, Xiaowei, Choi, Harry, Dimwamwa, Elaida, Ope, Omotayo, Shannan, Batool, Basu, Devraj, Zhang, Dongmei, Guha, Manti, Xiao, Min, Randell, Sergio, Sproesser, Katrin, Xu, Wei, Liu, Jephrey, Karakousis, Giorgos C, Schuchter, Lynn M, Gangadhar, Tara C, Amaravadi, Ravi K, Gu, Mengnan, Xu, Caiyue, Ghosh, Abheek, Xu, Weiting, Tian, Tian, Zhang, Jie, Zha, Shijie, Liu, Qin, Brafford, Patricia, Weeraratna, Ashani, Davies, Michael A, Wargo, Jennifer A, Avadhani, Narayan G, Lu, Yiling, Mills, Gordon B, Altieri, Dario C, Flaherty, Keith T, Herlyn, Meenhard

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A Multicenter Phase I Study Evaluating Dual PI3K and BRAF Inhibition with PX-866 and Vemurafenib in Patients with Advanced BRAF V600-Mutant Solid Tumors von Yam, Clinton, Xu, Xiaowei, Davies, Michael A, Gimotty, Phyllis A, Morrissette, Jennifer J D, Tetzlaff, Michael T, Wani, Khalida M, Liu, Shujing, Deng, Wanleng, Buckley, Meghan, Zhao, Jianhua, Amaravadi, Ravi K, Haas, Naomi B, Kudchadkar, Ragini R, Pavlick, Anna C, Sosman, Jeffrey A, Tawbi, Hussein, Walker, Luke, Schuchter, Lynn M, Karakousis, Giorgos C, Gangadhar, Tara C

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