Discovery of LRRK2 inhibitors by using an ensemble of virtual screening methods von Gancia, Emanuela, De Groot, Marcel, Burton, Brenda, Clark, David E.

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Discovery of Spiro-azaindoline Inhibitors of Hematopoietic Progenitor Kinase 1 (HPK1) von Chan, Bryan K, Seward, Eileen, Lainchbury, Michael, Brewer, Thomas F, An, Le, Blench, Toby, Cartwright, Matthew W, Chan, Grace Ka Yan, Choo, Edna F, Drummond, Jason, Elliott, Richard L, Gancia, Emanuela, Gazzard, Lewis, Hu, Baihua, Jones, Graham E, Luo, Xifeng, Madin, Andrew, Malhotra, Sushant, Moffat, John G, Pang, Jodie, Salphati, Laurent, Sneeringer, Christopher J, Stivala, Craig E, Wei, Binqing, Wang, Weiru, Wu, Ping, Heffron, Timothy P

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Mycobacterium tuberculosis Chaperonin 10 Is Secreted in the Macrophage Phagosome: Is Secretion Due to Dissociation and Adoption of a Partially Helical Structure at the Membrane? von Fossati, Gianluca, Izzo, Gaetano, Rizzi, Emanuele, Gancia, Emanuela, Modena, Daniela, Moras, Maria Luisa, Niccolai, Neri, Giannozzi, Elena, Spiga, Ottavia, Bono, Letizia, Marone, Piero, Leone, Eugenio, Mangili, Francesca, Harding, Stephen, Errington, Neil, Walters, Christopher, Henderson, Brian, Roberts, Michael M, Coates, Anthony R M, Casetta, Bruno, Mascagni, Paolo

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8-Fluoroimidazo[1,2-a]pyridine: Synthesis, physicochemical properties and evaluation as a bioisosteric replacement for imidazo[1,2-a]pyrimidine in an allosteric modulator ligand of... von Humphries, Alexander C., Gancia, Emanuela, Gilligan, Myra T., Goodacre, Simon, Hallett, David, Merchant, Kevin J., Thomas, Steve R.

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A reversed sulfonamide series of selective RORc inverse agonists von van Niel, Monique B, Fauber, Benjamin P, Cartwright, Matthew, Gaines, Simon, Killen, Jonathan C, René, Olivier, Ward, Stuart I, de Leon Boenig, Gladys, Deng, Yuzhong, Eidenschenk, Céline, Everett, Christine, Gancia, Emanuela, Ganguli, Arunima, Gobbi, Alberto, Hawkins, Julie, Johnson, Adam R, Kiefer, James R, La, Hank, Lockey, Peter, Norman, Maxine, Ouyang, Wenjun, Qin, Ann, Wakes, Nicole, Waszkowycz, Bohdan, Wong, Harvey

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Estimation of pKa Using Semiempirical Molecular Orbital Methods. Part 1: Application to Phenols and Carboxylic Acids von Tehan, Benjamin G., Lloyd, Edward J., Wong, Margaret G., Pitt, Will R., Montana, John G., Manallack, David T., Gancia, Emanuela

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Theoretical hydrogen bonding parameters for drug design von Gancia, Emanuela, Montana, John G., Manallack, David T.

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Global 3D-QSAR methods: MS-WHIM and autocorrelation von Gancia, E, Bravi, G, Mascagni, P, Zaliani, A

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Estimation of pKa Using Semiempirical Molecular Orbital Methods. Part 2: Application to Amines, Anilines and Various Nitrogen Containing Heterocyclic Compounds von Tehan, Benjamin G., Lloyd, Edward J., Wong, Margaret G., Pitt, Will R., Gancia, Emanuela, Manallack, David T.

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Azaindoles as inhibitors of HPK1 von Malhotra, Sushant, Madin, Andrew, Seward, Eileen, Gazzard, Lewis, Heffron, Timothy, Wei, BinQing, Gancia, Emanuela, Hu, Yonghan, Chan, Bryan, Lainchbury, Michael

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SUBSTITUTED TETRAHYDROPYRROLO-PYRIDINONE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS von Myers, Jason, Evans, David G, Wagstaff, Niall, Gancia, Emanuela, Ahmad, Nadia M, Roussel, Fabien Jean Ghislain, Audia, James Edmund, Monn, James, Gardinier, Kevin Matthew, Skidmore, Elizabeth Anne

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SUBSTITUTED DIHYDROPYRROLO[3, 4-D]PYRIMIDINE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS von MONN, James, AUDIA, James Edmund, GARDINIER, Kevin Matthew, MYERS, Jason, EVANS, David G, SKIDMORE, Elizabeth Anne, GANCIA, Emanuela, AHMAD, Nadia M, WAGSTAFF, Niall

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SUBSTITUTED TETRAHYDROPYRROLO-PYRIDINONE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS von MONN, James, ROUSSEL, Fabien Jean Ghislain, AUDIA, James Edmund, GARDINIER, Kevin Matthew, MYERS, Jason, EVANS, David G, SKIDMORE, Elizabeth Anne, GANCIA, Emanuela, AHMAD, Nadia M, WAGSTAFF, Niall

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SUBSTITUTED TETRAHYDROPYRROLO-PYRIDINONE COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS von MONN, James, ROUSSEL, Fabien Jean Ghislain, AUDIA, James Edmund, GARDINIER, Kevin Matthew, MYERS, Jason, EVANS, David G, GANCIA, Emanuela, AHMAD, Nadia M, WAGSTAFF, Niall

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A Consensus Neural Network-Based Technique for Discriminating Soluble and Poorly Soluble Compounds von Manallack, David T, Tehan, Benjamin G, Gancia, Emanuela, Hudson, Brian D, Ford, Martyn G, Livingstone, David J, Whitley, David C, Pitt, Will R

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AZAINDOLES AS INHIBITORS OF HPK1 von GAZZARD, Lewis, MADIN, Andrew, GANCIA, Emanuela, HEFFRON, Timothy, SEWARD, Eileen, MALHOTRA, Sushant, WEI, BinQing, LAINCHBURY, Michael, CHAN, Bryan, HU, Yonghan

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S1PR4 RECEPTOR ANTAGONISTS AND METHODS OF USE THEREOF von GANCIA, Emanuela, BULL, Richard, JACKSON, Philip, KNIGHT, Jamie, LEVENSON, Jonathan Max, LARSON, Kelley Cronin, TATE, Barbara, JENNINGS, Neil, HYND, George, CRIDLAND, Andrew, MILLER, Thomas Allen, MARTENS, Lauren, BRUHN, Suzanne

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ENZYME INHIBITORS von CLARK, David Edward, PITTAWAY, Rachael, WRIGGLESWORTH, Joseph William, GANCIA, Emanuela, EVANS, David Michael, OBARA, Alicja Stela, MAZZACANI, Alessandro, EDWARDS, Hannah Joy

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ARYL SULTAM DERIVATIVES AS RORC MODULATORS von WINSHIP, Paul, GANCIA, Emanuela, LADDUWAHETTY, Tammy, FAUBER, Benjamin, RENE, Olivier, VESEY, David

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NAPHTHYRIDINES AS INHIBITORS OF HPK1 von RAJAPAKSA, Naomi, GANCIA, Emanuela, MALHOTRA, Sushant, CARTWRIGHT, Matthew W, ZHOU, Aihe, GOOD, Andrew, GAZZARD, Lewis, SIU, Michael, JONES, Graham, LU, Aijun, DANIELS, Blake, STIVALA, Craig, CHAN, Bryan, TELLIS, John, MENDONCA, Rohan, FAVOR, David, WANG, Weiru, FONG, Kin Chiu, MADIN, Andrew, SEWARD, Eileen, DROBNICK, Joy, LAINCHBURY, Michael, HU, Yonghan, HU, Baihua, HEFFRON, Timothy, LIANG, Jun, WEI, BinQing, HUESTIS, Malcolm

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