EZH2 Supports Osteoclast Differentiation and Bone Resorption Via Epigenetic and Cytoplasmic Targets von Adamik, Juraj, Pulugulla, Sree H, Zhang, Peng, Sun, Quanhong, Lontos, Konstantinos, Macar, David A, Auron, Philip E, Galson, Deborah L

Volltext

EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma-Induced Epigenetic Suppression of Osteoblast Differentiation von Adamik, Juraj, Jin, Shunqian, Sun, Quanhong, Zhang, Peng, Weiss, Kurt R, Anderson, Judith L, Silbermann, Rebecca, Roodman, G David, Galson, Deborah L

Volltext

The Role of Semaphorin 4D in Bone Remodeling and Cancer Metastasis von Lontos, Konstantinos, Adamik, Juraj, Tsagianni, Anastasia, Galson, Deborah L, Chirgwin, John M, Suvannasankha, Attaya

Volltext

Nuclear Factor of Activated T-cells (NFAT) Rescues Osteoclastogenesis in Precursors Lacking c-Fos von Matsuo, Koichi, Galson, Deborah L., Zhao, Chen, Peng, Lan, Laplace, Catherine, Wang, Kent Z.Q., Bachler, Marcus A., Amano, Hitoshi, Aburatani, Hiroyuki, Ishikawa, Hiromichi, Wagner, Erwin F.

Volltext

Osteoblast suppression in multiple myeloma bone disease von Adamik, Juraj, Galson, Deborah L, Roodman, G David

Volltext

Resveratrol triggers the pro-apoptotic endoplasmic reticulum stress response and represses pro-survival XBP1 signaling in human multiple myeloma cells von Wang, Feng-Ming, Galson, Deborah L, Roodman, G. David, Ouyang, Hongjiao

Volltext

Monocyte chemotactic protein-1 (MCP-1) acts as a paracrine and autocrine factor for prostate cancer growth and invasion von Lu, Yi, Cai, Zhong, Galson, Deborah L., Xiao, Guozhi, Liu, Yulin, George, Diane E., Melhem, Mona F., Yao, Zhi, Zhang, Jian

Volltext

Activating transcription factor 4 regulates osteoclast differentiation in mice von Cao, Huiling, Yu, Shibing, Yao, Zhi, Galson, Deborah L, Jiang, Yu, Zhang, Xiaoyan, Fan, Jie, Lu, Binfeng, Guan, Youfei, Luo, Min, Lai, Yumei, Zhu, Yibei, Kurihara, Noriyoshi, Patrene, Kenneth, Roodman, G David, Xiao, Guozhi

Volltext

Epigenetic-Based Mechanisms of Osteoblast Suppression in Multiple Myeloma Bone Disease von Adamik, Juraj, Roodman, G David, Galson, Deborah L

Volltext

Distinct mechanisms for induction and tolerance regulate the immediate early genes encoding interleukin 1β and tumor necrosis factor α von Adamik, Juraj, Wang, Kent Z Q, Unlu, Sebnem, Su, An-Jey A, Tannahill, Gillian M, Galson, Deborah L, O'Neill, Luke A, Auron, Philip E

Volltext

XRK3F2 Inhibition of p62-ZZ Domain Signaling Rescues Myeloma-Induced GFI1-Driven Epigenetic Repression of the Runx2 Gene in Pre-osteoblasts to Overcome Differentiation Suppression von Adamik, Juraj, Silbermann, Rebecca, Marino, Silvia, Sun, Quanhong, Anderson, Judith L, Zhou, Dan, Xie, Xiang-Qun, Roodman, G David, Galson, Deborah L

Volltext

Amylin Inhibits Bone Resorption While the Calcitonin Receptor Controls Bone Formation in vivo von Dacquin, Romain, Davey, Rachel A., Laplace, Catherine, Levasseur, Régis, Morris, Howard A., Goldring, Steven R., Gebre-Medhin, Samuel, Galson, Deborah L., Zajac, Jeffrey D., Karsenty, Gérard

Volltext

Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis von Petrusca, Daniela N, Toscani, Denise, Wang, Feng-Ming, Park, Cheolkyu, Crean, Colin D, Anderson, Judith L, Marino, Silvia, Mohammad, Khalid S, Zhou, Dan, Silbermann, Rebecca, Sun, Quanhong, Kurihara, Noriyoshi, Galson, Deborah L, Giuliani, Nicola, Roodman, G David

Volltext

CXCL16 Functions as a Novel Chemotactic Factor for Prostate Cancer Cells In vitro von Lu, Yi, Wang, Jianhua, Xu, Yang, Koch, Alisa E, Cai, Zhong, Chen, Xue, Galson, Deborah L, Taichman, Russell S, Zhang, Jian

Volltext

Measles virus nucleocapsid protein, a key contributor to Paget's disease, increases IL-6 expression via down-regulation of FoxO3/Sirt1 signaling von Wang, Feng-Ming, Sarmasik, Aliye, Hiruma, Yuko, Sun, Quanhong, Sammut, Bénédicte, Windle, Jolene J, Roodman, G. David, Galson, Deborah L

Volltext

Role of ATF7‐TAF12 interactions in the vitamin D response hypersensitivity of osteoclast precursors in Paget's disease von Teramachi, Jumpei, Hiruma, Yuko, Ishizuka, Seiichi, Ishizuka, Hisako, Brown, Jacques P, Michou, Laëtitia, Cao, Huiling, Galson, Deborah L, Subler, Mark A, Zhou, Hua, Dempster, David W, Windle, Jolene J, Roodman, G David, Kurihara, Noriyoshi

Volltext

ADAM8 enhances osteoclast precursor fusion and osteoclast formation in vitro and in vivo von Ishizuka, Hisako, García‐Palacios, Verónica, Lu, Ganwei, Subler, Mark A, Zhang, Heju, Boykin, Christina S, Choi, Sun Jin, Zhao, Liena, Patrene, Kenneth, Galson, Deborah L, Blair, Harry C, Hadi, Tamer M, Windle, Jolene J, Kurihara, Noriyoshi, Roodman, G David

Volltext

PTHrP‐induced MCP‐1 production by human bone marrow endothelial cells and osteoblasts promotes osteoclast differentiation and prostate cancer cell proliferation and invasion in vit... von Lu, Yi, Xiao, Guozhi, Galson, Deborah L., Nishio, Yoshihiko, Mizokami, Atsushi, Keller, Evan T., Yao, Zhi, Zhang, Jian

Volltext

Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis von Wu, Chuanyue, Jiao, Hongli, Lai, Yumei, Zheng, Wei, Chen, Ka, Qu, Hong, Deng, Weimin, Song, Pingping, Zhu, Ke, Cao, Huiling, Galson, Deborah L., Fan, Jie, Im, Hee-Jeong, Liu, Yujie, Chen, Ju, Chen, Di, Xiao, Guozhi

Volltext

Role of Sphingolipids in Multiple Myeloma Progression, Drug Resistance, and Their Potential as Therapeutic Targets von Petrusca, Daniela N., Lee, Kelvin P., Galson, Deborah L.

Volltext