Efficacy and safety of larotrectinib in TRK fusion-positive primary central nervous system tumors von Doz, François, van Tilburg, Cornelis M, Geoerger, Birgit, Højgaard, Martin, Øra, Ingrid, Boni, Valentina, Capra, Michael, Chisholm, Julia, Chung, Hyun Cheol, DuBois, Steven G, Gallego-Melcon, Soledad, Gerber, Nicolas U, Goto, Hiroaki, Grilley-Olson, Juneko E, Hansford, Jordan R, Hong, David S, Italiano, Antoine, Kang, Hyoung Jin, Nysom, Karsten, Thorwarth, Anne, Stefanowicz, Joanna, Tahara, Makoto, Ziegler, David S, Gavrilovic, Igor T, Norenberg, Ricarda, Dima, Laura, De La Cuesta, Esther, Laetsch, Theodore W, Drilon, Alexander, Perreault, Sebastien

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Addition of dose-intensified doxorubicin to standard chemotherapy for rhabdomyosarcoma (EpSSG RMS 2005): a multicentre, open-label, randomised controlled, phase 3 trial von Bisogno, Gianni, Jenney, Meriel, Bergeron, Christophe, Gallego Melcón, Soledad, Ferrari, Andrea, Oberlin, Odile, Carli, Modesto, Stevens, Michael, Kelsey, Anna, De Paoli, Angela, Gaze, Mark N, Martelli, Helene, Devalck, Christine, Merks, Johannes H, Ben-Arush, Myriam, Glosli, Heidi, Chisholm, Julia, Orbach, Daniel, Minard-Colin, Veronique, De Salvo, Gian Luca, Cesen, Maja, Rose, Adriana, Ferman, Sima, Mudry, Peter, Sejnova, Daniela, Dal Bianco, Paola, Zanetti, Ilaria, Niggli, Felix, Rogers, Timothy, Cecchetto, Giovanni, De Corti, Federica, Guerin, Florent, Terwisscha, Sheila, Ranchere, Dominique, Alaggio, Rita, Shipley, Janet, Rosolen, Angelo, Mandeville, Henry, Scarzello, Giovanni, Bernier, Valerie, McHugh, Kieran

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Randomized Phase II Trial of Vincristine-Irinotecan With or Without Temozolomide, in Children and Adults With Relapsed or Refractory Rhabdomyosarcoma: A European Paediatric Soft Ti... von Defachelles, Anne-Sophie, Bogart, Emilie, Casanova, Michela, Merks, Johannes H. M., Bisogno, Gianni, Calareso, Giuseppina, Melcon, Soledad Gallego, Gatz, Susanne Andrea, Le Deley, Marie-Cecile, McHugh, Kieran, Probst, Alicia, Rocourt, Nathalie, van Rijn, Rick R., Wheatley, Keith, Minard-Colin, Veronique, Chisholm, Julia C.

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A new standard of care for patients with high-risk rhabdomyosarcoma? – Authors' reply von Bisogno, Gianni, Ferrari, Andrea, Melcon, Soledad Gallego, De Salvo, Gian Luca, Bergeron, Christophe, Jenney, Meriel

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Prognostic factors in desmoid tumours: an example of translational oncology von Melcón, Soledad Gallego

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Phase I results of a phase I/II study of weekly nab-paclitaxel in paediatric patients with recurrent/refractory solid tumours: A collaboration with innovative therapies for childre... von Moreno, Lucas, Casanova, Michela, Chisholm, Julia C., Berlanga, Pablo, Chastagner, Pascal B., Baruchel, Sylvain, Amoroso, Loredana, Gallego Melcón, Soledad, Gerber, Nicolas U., Bisogno, Gianni, Fagioli, Franca, Geoerger, Birgit, Glade Bender, Julia L., Aerts, Isabelle, Bergeron, Christophe, Hingorani, Pooja, Elias, Ileana, Simcock, Mathew, Ferrara, Stefano, Le Bruchec, Yvan, Slepetis, Ruta, Chen, Nianhang, Vassal, Gilles

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Incorporating new therapies in the treatment of paediatric solid tumours von Melcón, Soledad Gallego

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Reply to H. B et al von Defachelles, Anne-Sophie, Bogart, Emilie, Casanova, Michela, Merks, Johannes H M, Bisogno, Gianni, Calareso, Giuseppina, Melcon, Soledad Gallego, Gatz, Susanne Andrea, Le Deley, Marie-Cécile, McHugh, Kieran, Probst, Alicia, Rocourt, Nathalie, van Rijn, Rick R, Minard-Colin, Véronique, Chisholm, Julia C

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Phase I/II study of single-agent lenvatinib in children and adolescents with refractory or relapsed solid malignancies and young adults with osteosarcoma (ITCC-050) von Gaspar, N., Campbell-Hewson, Q., Gallego Melcon, S., Locatelli, F., Venkatramani, R., Hecker-Nolting, S., Gambart, M., Bautista, F., Thebaud, E., Aerts, I., Morland, B., Rossig, C., Canete Nieto, A., Longhi, A., Lervat, C., Entz-Werle, N., Strauss, S.J., Marec-Berard, P., Okpara, C.E., He, C., Dutta, L., Casanova, M.

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Efficacy and safety of larotrectinib in TRK fusion-positive primary central nervous system tumors von Doz, François, van Tilburg, Cornelis M, Geoerger, Birgit, Højgaard, Martin, Øra, Ingrid, Boni, Valentina, Capra, Michael, Chisholm, Julia, Chung, Hyun Cheol, DuBois, Steven G, Gallego-Melcon, Soledad, Gerber, Nicolas U, Goto, Hiroaki, Grilley-Olson, Juneko E, Hansford, Jordan R, Hong, David S, Italiano, Antoine, Kang, Hyoung Jin, Nysom, Karsten, Thorwarth, Anne, Stefanowicz, Joanna, Tahara, Makoto, Ziegler, David S, Gavrilovic, Igor T, Norenberg, Ricarda, Dima, Laura, De La Cuesta, Esther, Laetsch, Theodore W, Drilon, Alexander, Perreault, Sebastien

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Maintenance low-dose chemotherapy in patients with high-risk (HR) rhabdomyosarcoma (RMS): A report from the European Paediatric Soft Tissue Sarcoma Study Group (EpSSG) von Bisogno, Gianni, De Salvo, Gian Luca, Bergeron, Christophe, Jenney, Meriel, Merks, Johannes H.M., Minard-Colin, Veronique, Orbach, Daniel, Glosli, Heidi, Chisholm, Julia, Casanova, Michela, Gallego Melcon, Soledad, Ferrari, Andrea

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Single-agent expansion cohort of lenvatinib (LEN) and combination dose-finding cohort of LEN + etoposide (ETP) + ifosfamide (IFM) in patients (pts) aged 2 to ≤25 years with relapse... von Gaspar, Nathalie, Casanova, Michela, Sirvent, Francisco José Bautista, Venkatramani, Rajkumar, Morland, Bruce, Gambart, Marion, Thebaud, Estelle, Strauss, Sandra J, Locatelli, Franco, Gallego Melcon, Soledad, Canete, Adela, Bielack, Stefan S., Rossig, Claudia, Aerts, Isabelle, Marec-Berard, Perrine, Kraljevic, Silvija, Hayato, Seiichi, He, Cixin, Dutcus, Corina E., Campbell-Hewson, Quentin

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Older adolescents and young adults with cancer: a different subset of patients? von Gallego Melcón, Soledad

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Single-agent dose-finding cohort of a phase 1/2 study of lenvatinib (LEN) in children and adolescents with refractory or relapsed solid tumors von Gaspar, Nathalie, Gallego Melcon, Maria Soledad, Venkatramani, Rajkumar, Bielack, Stefan S., Casanova, Michela, Locatelli, Franco, Thebaud, Estelle, Rigaud, Charlotte, Abbou, Samuel, Gambart, Marion, Morland, Bruce, Aerts, Isabelle, Kraljevic, Silvija, Li, Di, Maniar, Hina, Hayato, Seiichi, Dutcus, Corina E, Campbell Hewson, Quentin

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Engineering pH-Sensitive Stable Nanovesicles for Delivery of MicroRNA Therapeutics von Boloix, Ariadna, Feiner Gracia, Natalia, Kober, Marina, Repetto, Javier, Pascarella, Rosa, Soriano, Aroa, Masanas, Marc, Segovia, Nathaly, Vargas Nadal, Guillem, Merlo Mas, Josep, Danino, Dganit, Abutbul-Ionita, Inbal, Foradada, Laia, Roma, Josep, Cordoba, Alba, Sala, Santi, Sánchez de Toledo, Josep, Gallego Melcón, Soledad, Veciana, Jaume, Albertazzi, Lorenzo, Segura, Miguel F, Ventosa, Nora

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CTNI-58. EFFICACY AND SAFETY OF LAROTRECTINIB IN ADULT AND PEDIATRIC PATIENTS WITH TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION-POSITIVE PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS von Doz, François, van Tilburg, Cornelis M, Geoerger, Birgit, Nysom, Karsten, Øra, Ingrid, Boni, Valentina, Chisholm, Julia, Chung, Hyun Cheol, DuBois, Steven G, Melcón, Soledad Gallego, Gerber, Nicolas U, Goto, Hiroaki, Grilley-Olsen, Juneko E, Hansford, Jordan R, Hong, David S, Italiano, Antoine, Kang, Hyoung Jin, Capra, Michael, Schulte, Johannes H, Stefanowicz, Joanna, Tahara, Makoto, Ziegler, David S, Gavrilovic, Igor T, Norenberg, Ricarda, Dima, Laura, De La Cuesta, Esther, Laetsch, Theodore W, Drilon, Alexander, Perreault, Sébastien

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Rhabdomyosarcoma: present and future perspectives in diagnosis and treatment von Melcón, Soledad Gallego, Codina, José Sánchez de Toledo

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Personalized Medicine Test of Multi-Drug Protocols Ex Vivo for Hematological Malignancies von Bennett, Teresa A, Sapia, Sandra, Primo, Daniel, Suarez, Lilia, Lago, Santiago, Matoses, Maria, Espinosa, Ana, Tudela, Consuelo, Arroyo, Elena, Gorrochategui, Julian, Jackson, William C, Okun, Alex, Lopez, Horacio Hector, Gornemann, Isolde, Melcon, Soledad Gallego, de Heredia, Cristina Diaz, Dapena, Jose Luis, Roma, Josep M, Delgado, Regina Garcia, Queipodellano, Mari Paz, Bailen, Alicia, Barrios, Manuel, Diez, Eva, Del Castillo, Santiago, Heiniger, Ana Isabel, de Toledo, Jose Sanchez, Ramirez, Manuel, Ortiz, Macarena, Gonzáalez, Marcos, San-Miguel, Jesús F., Ocio, Enrique M, Bosanquet, Andrew G., Orfao, Alberto, Ballesteros, Joan

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Screening Thousands of Drugs in Leukemia Patient Samples to Identify Novel Uses for Approved Drugs von Bennett, Teresa A, Sapia, Sandra, Primo, Daniel, Suarez, Lilia, Lago, Santiago, Matoses, Maria, Espinosa, Ana, Tudela, Consuelo, Arroyo, Elena, Jackson, William Coyt, Okun, Alex, Lopez, Horacio Hector, Gornemann, Isolde, Diez, Eva, Roma, Josep M, Dapena, Jose Luis, Melcon, Soledad Gallego, de Toledo, Jose Sanchez, Rosell, Ana, Del Castillo, Santiago, Bailen, Alicia, Heiniger, Ana Isabel, Díaz-Mediavilla, Joaquin, Prosper, Felipe, Ramirez Sr, Manuel, Ortiz, Macarena, González, Marcos, Dominguez-Gil, Alfonso, Troconiz, Iñaki F, de Fonseca, Fernando Rodriguez, Ocio, Enrique M, Saunders, Andrew, Montejo, Julieta, Caveda, Luis, Orfao, Alberto, Ballesteros, Joan

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Phase I results of a phase I/II study of weekly nab-paclitaxel in paediatric patients with recurrent/refractory solid tumours: A collaboration with innovative therapies for childre... von Moreno, Lucas, Casanova, Michela, Chisholm, Julia C, Berlanga, Pablo, Chastagner, Pascal B, Baruchel, Sylvain, Amoroso, Loredana, Gallego Melcón, Soledad, Gerber, Nicolas U, Bisogno, Gianni, Fagioli, Franca, Geoerger, Birgit, Glade Bender, Julia L, Aerts, Isabelle, Bergeron, Christophe, Hingorani, Pooja, Elias, Ileana, Simcock, Mathew, Ferrara, Stefano, Le Bruchec, Yvan, Slepetis, Ruta, Chen, Nianhang, Vassal, Gilles

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