Broadening the Spectrum of β-Lactam Antibiotics through Inhibition of Signal Peptidase Type I von THERIEN, Alex G, HUBER, Joann L, XIN GU, KEVIN, Nancy J, LAFLEUR, Josiane, LEAVITT, Penny S, LEBEAU-JACOB, Christian, LEE, Suzy S, LIN, Molly M, MICHELS, Anna A, OGAWA, Aimie M, PAINTER, Ronald E, WILSON, Kenneth E, PARISH, Craig A, PARK, Young-Whan, BENTON-PERDOMO, Liliana, PETCU, Mihai, PHILLIPS, John W, POWLES, Mary Ann, SKOREY, Kathryn I, TAM, John, TAN, Christopher M, YOUNG, Katherine, BEAULIEU, Patrick, WONG, Simon, WADDELL, Sherman T, MIESEL, Lynn, CARON, Alexandre, CLAVEAU, David, DESCHAMPS, Kathleen, DONALD, Robert G. K, GALGOCI, Andrew M, GALLANT, Michel

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Novel targets for valproic acid: up‐regulation of melatonin receptors and neurotrophic factors in C6 glioma cells von Rincón Castro, Lyda M., Gallant, Michel, Niles, Lennard P.

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The utilization of recombinant prostanoid receptors to determine the affinities and selectivities of prostaglandins and related analogs von Abramovitz, Mark, Adam, Mohammed, Boie, Yves, Carrière, Marie-Claude, Denis, Danielle, Godbout, Claude, Lamontagne, Sonia, Rochette, Chantal, Sawyer, Nicole, Tremblay, Nathalie M, Belley, Michel, Gallant, Michel, Dufresne, Claude, Gareau, Yves, Ruel, Rejean, Juteau, Helene, Labelle, Marc, Ouimet, Nathalie, Metters, Kathleen M

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis von Nicholson, Donald W, Ali, Ambereen, Thornberry, Nancy A, Vaillancourt, John P, Ding, Connie K, Gallant, Michel, Gareau, Yves, Griffin, Patrick R, Labelle, Marc, Lazebnik, Yuri A, Munday, Neil A, Raju, Sayyaparaju M, Smulson, Mark E, Yamin, Ting-Ting, Yu, Violeta L, Miller, Douglas K

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Differential Regulation of ATP Binding Cassette Protein A1 Expression and ApoA-I Lipidation by Niemann-Pick Type C1 in Murine Hepatocytes and Macrophages von Wang, Ming-Dong, Franklin, Vivian, Sundaram, Meenakshi, Kiss, Robert S., Ho, Kenneth, Gallant, Michel, Marcel, Yves L.

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Identification of RP-6685, an Orally Bioavailable Compound that Inhibits the DNA Polymerase Activity of Polθ von Bubenik, Monica, Mader, Pavel, Mochirian, Philippe, Vallée, Fréderic, Clark, Jillian, Truchon, Jean-François, Perryman, Alexander L., Pau, Victor, Kurinov, Igor, Zahn, Karl E., Leclaire, Marie-Eve, Papp, Robert, Mathieu, Marie-Claude, Hamel, Martine, Duffy, Nicole M., Godbout, Claude, Casas-Selves, Matias, Falgueyret, Jean-Pierre, Baruah, Prasamit S., Nicolas, Olivier, Stocco, Rino, Poirier, Hugo, Martino, Giovanni, Fortin, Alexanne Bonneau, Roulston, Anne, Chefson, Amandine, Dorich, Stéphane, St-Onge, Miguel, Patel, Purvish, Pellerin, Charles, Ciblat, Stéphane, Pinter, Thomas, Barabé, Francis, El Bakkouri, Majida, Parikh, Paranjay, Gervais, Christian, Sfeir, Agnel, Mamane, Yael, Morris, Stephen J., Black, W. Cameron, Sicheri, Frank, Gallant, Michel

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Discovery of an Orally Bioavailable and Selective PKMYT1 Inhibitor, RP-6306 von Szychowski, Janek, Papp, Robert, Dietrich, Evelyne, Liu, Bingcan, Vallée, Frédéric, Leclaire, Marie-Eve, Fourtounis, Jimmy, Martino, Giovanni, Perryman, Alexander L., Pau, Victor, Yin, Shou Yun, Mader, Pavel, Roulston, Anne, Truchon, Jean-Francois, Marshall, C. Gary, Diallo, Mohamed, Duffy, Nicole M., Stocco, Rino, Godbout, Claude, Bonneau-Fortin, Alexanne, Kryczka, Rosie, Bhaskaran, Vivek, Mao, Daniel, Orlicky, Stephen, Beaulieu, Patrick, Turcotte, Pascal, Kurinov, Igor, Sicheri, Frank, Mamane, Yael, Gallant, Michel, Black, W. Cameron

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Interspecies in vitro metabolism of the phosphodiesterase-4 (PDE4) inhibitor L-454,560 von Bateman, Kevin P., Trimble, Laird, Chauret, Nathalie, Silva, Jose, Day, Stephen, Macdonald, Dwight, Dube, Daniel, Gallant, Michel, Mastracchio, Anthony, Perrier, Helene, Girard, Yves, Nicoll-Griffith, Deborah

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Structure-activity relationship studies on ortho-substituted cinnamic acids, a new class of selective EP3 antagonists von BELLEY, Michel, GALLANT, Michel, TREMBLAY, Nathalie, LAMONTAGNE, Sonia, CARRIERE, Marie-Claude, DENIS, Danielle, GREIG, Gillian M, SLIPETZ, Deborah, METTERS, Kathleen M, GORDON, Robert, CHI CHUNG CHAN, ZAMBONI, Robert J, ROY, Bruno, HOUDE, Karine, LACHANCE, Nicolas, LABELLE, Marc, TRIMBLE, Laird A, CHAURET, Nathalie, CHUN LI, SAWYER, Nicole

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The three-dimensional structure of apopain/CPP32, a key mediator of apoptosis von Rotonda, Jennifer, Nicholson, Donald W, Fazil, Kimberly M, Gallant, Michel, Gareau, Yves, Labelle, Marc, Peterson, Erin P, Rasper, Dita M, Ruel, Réjean, Vaillancourt, John P, Thornberry, Nancy A, Becker, Joseph W

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A stereoselective synthesis of indole-.beta.-N-glycosides: an application to the synthesis of rebeccamycin von Gallant, Michel, Link, James T, Danishefsky, Samuel J

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Pharmacological Characterization of MK-7246, a Potent and Selective CRTH2 (Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type 2 Cells) Antagonist von Gervais, Francois G., Sawyer, Nicole, Stocco, Rino, Hamel, Martine, Krawczyk, Connie, Sillaots, Susan, Denis, Danielle, Wong, Elizabeth, Wang, Zhaoyin, Gallant, Michel, Abraham, William M., Slipetz, Deborah, Crackower, Michael A., O’Neill, Gary P.

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The first synthesis of a fully functionalized core structure of staurosporine: sequential indolyl glycosidation by endo and exo glycals von Link, J. T, Gallant, Michel, Danishefsky, Samuel J, Huber, Susan

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Discovery of MK-0952, a selective PDE4 inhibitor for the treatment of long-term memory loss and mild cognitive impairment von Gallant, Michel, Aspiotis, Renee, Day, Stephen, Dias, Rebecca, Dubé, Daniel, Dubé, Laurence, Friesen, Richard W., Girard, Mario, Guay, Daniel, Hamel, Pierre, Huang, Zheng, Lacombe, Patrick, Laliberté, Sebastien, Lévesque, Jean-François, Liu, Susana, Macdonald, Dwight, Mancini, Joseph, Nicholson, Donald W., Styhler, Angela, Townson, Karen, Waters, Kerry, Young, Robert N., Girard, Yves

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Discovery of MK-7246, a selective CRTH2 antagonist for the treatment of respiratory diseases von Gallant, Michel, Beaulieu, Christian, Berthelette, Carl, Colucci, John, Crackower, Michael A., Dalton, Chad, Denis, Danielle, Ducharme, Yves, Friesen, Richard W., Guay, Daniel, Gervais, François G., Hamel, Martine, Houle, Robert, Krawczyk, Connie M., Kosjek, Birgit, Lau, Stephen, Leblanc, Yves, Lee, Ernest E., Levesque, Jean-François, Mellon, Christophe, Molinaro, Carmela, Mullet, Wayne, O’Neill, Gary P., O’Shea, Paul, Sawyer, Nicole, Sillaots, Susan, Simard, Daniel, Slipetz, Deborah, Stocco, Rino, Sørensen, Dan, Truong, Vouy Linh, Wong, Elizabeth, Wu, Jin, Zaghdane, Helmi, Wang, Zhaoyin

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Azaindoles as potent CRTH2 receptor antagonists von Simard, Daniel, Leblanc, Yves, Berthelette, Carl, Zaghdane, M. Helmi, Molinaro, Carmela, Wang, Zhaoyin, Gallant, Michel, Lau, Stephen, Thao, Trinh, Hamel, Martine, Stocco, Rino, Sawyer, Nicole, Sillaots, Susan, Gervais, Francois, Houle, Robert, Lévesque, Jean-François

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New indole amide derivatives as potent CRTH2 receptor antagonists von Zaghdane, Helmi, Boyd, Michael, Colucci, John, Simard, Daniel, Berthelette, Carl, Leblanc, Yves, Wang, Zhaoyin, Houle, Robert, Lévesque, Jean François, Molinaro, Carmela, Hamel, Martine, Stocco, Rino, Sawyer, Nicole, Sillaots, Susan, Gervais, François, Gallant, Michel

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Reducing the Peptidyl Features of Caspase-3 Inhibitors:  A Structural Analysis von Becker, Joseph W, Rotonda, Jennifer, Soisson, Stephen M, Aspiotis, Renee, Bayly, Christopher, Francoeur, Sébastien, Gallant, Michel, Garcia-Calvo, Marga, Giroux, Andre, Grimm, Erich, Han, Yongxin, McKay, Dan, Nicholson, Donald W, Peterson, Erin, Renaud, Johanne, Roy, Sophie, Thornberry, Nancy, Zamboni, Robert

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Hydrogen-bonded dimers. Direct study of the interconversion of pyridone dimers and hydroxypyridine monomers by low-temperature nuclear magnetic resonance spectroscopy von Gallant, Michel, Phan Viet Minh Tan, Wuest, James D.

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Addressing time-dependent CYP 3A4 inhibition observed in a novel series of substituted amino propanamide renin inhibitors, a case study von Chen, Austin, Dubé, Daniel, Dubé, Laurence, Gagné, Sébastien, Gallant, Michel, Gaudreault, Mireille, Grimm, Erich, Houle, Robert, Lacombe, Patrick, Laliberté, Sébastien, Liu, Suzanna, MacDonald, Dwight, Mackay, Bruce, Martin, David, McKay, Dan, Powell, David, Lévesque, Jean-François

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