Enzymes revolutionize the bioproduction of value-added compounds: From enzyme discovery to special applications von Wiltschi, Birgit, Cernava, Tomislav, Dennig, Alexander, Galindo Casas, Meritxell, Geier, Martina, Gruber, Steffen, Haberbauer, Marianne, Heidinger, Petra, Herrero Acero, Enrique, Kratzer, Regina, Luley-Goedl, Christiane, Müller, Christina A., Pitzer, Julia, Ribitsch, Doris, Sauer, Michael, Schmölzer, Katharina, Schnitzhofer, Wolfgang, Sensen, Christoph W., Soh, Jung, Steiner, Kerstin, Winkler, Christoph K., Winkler, Margit, Wriessnegger, Tamara

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Site-Dependent Degradation of a Non-Cleavable Auristatin-Based Linker-Payload in Rodent Plasma and Its Effect on ADC Efficacy von Dorywalska, Magdalena, Strop, Pavel, Melton-Witt, Jody A, Hasa-Moreno, Adela, Farias, Santiago E, Galindo Casas, Meritxell, Delaria, Kathy, Lui, Victor, Poulsen, Kris, Sutton, Janette, Bolton, Gary, Zhou, Dahui, Moine, Ludivine, Dushin, Russell, Tran, Thomas-Toan, Liu, Shu-Hui, Rickert, Mathias, Foletti, Davide, Shelton, David L, Pons, Jaume, Rajpal, Arvind

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Decoupling Protein Production from Cell Growth Enhances the Site-Specific Incorporation of Noncanonical Amino Acids in E. coli von Galindo Casas, Meritxell, Stargardt, Patrick, Mairhofer, Juergen, Wiltschi, Birgit

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Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker Design von Dorywalska, Magdalena, Dushin, Russell, Moine, Ludivine, Farias, Santiago E, Zhou, Dahui, Navaratnam, Thayalan, Lui, Victor, Hasa-Moreno, Adela, Casas, Meritxell Galindo, Tran, Thomas-Toan, Delaria, Kathy, Liu, Shu-Hui, Foletti, Davide, O'Donnell, Christopher J, Pons, Jaume, Shelton, David L, Rajpal, Arvind, Strop, Pavel

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Effect of Attachment Site on Stability of Cleavable Antibody Drug Conjugates von Dorywalska, Magdalena, Strop, Pavel, Melton-Witt, Jody A, Hasa-Moreno, Adela, Farias, Santiago E, Galindo Casas, Meritxell, Delaria, Kathy, Lui, Victor, Poulsen, Kris, Loo, Carole, Krimm, Stellanie, Bolton, Gary, Moine, Ludivine, Dushin, Russell, Tran, Thomas-Toan, Liu, Shu-Hui, Rickert, Mathias, Foletti, Davide, Shelton, David L, Pons, Jaume, Rajpal, Arvind

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Mass Spectrometric Characterization of Transglutaminase Based Site-Specific Antibody–Drug Conjugates von Farias, Santiago E, Strop, Pavel, Delaria, Kathy, Galindo Casas, Meritxell, Dorywalska, Magdalena, Shelton, David L, Pons, Jaume, Rajpal, Arvind

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Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain von Shcherbatko, Anatoly, Rossi, Andrea, Foletti, Davide, Zhu, Guoyun, Bogin, Oren, Galindo Casas, Meritxell, Rickert, Mathias, Hasa-Moreno, Adela, Bartsevich, Victor, Crameri, Andreas, Steiner, Alexander R., Henningsen, Robert, Gill, Avinash, Pons, Jaume, Shelton, David L., Rajpal, Arvind, Strop, Pavel

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Generating Bispecific Human IgG1 and IgG2 Antibodies from Any Antibody Pair von Strop, Pavel, Ho, Wei-Hsien, Boustany, Leila M., Abdiche, Yasmina N., Lindquist, Kevin C., Farias, Santiago E., Rickert, Mathias, Appah, Charles Takeshi, Pascua, Edward, Radcliffe, Teresa, Sutton, Janette, Chaparro-Riggers, Javier, Chen, Wei, Casas, Meritxell Galindo, Chin, Sherman Michael, Wong, Oi Kwan, Liu, Shu-Hui, Vergara, German, Shelton, Dave, Rajpal, Arvind, Pons, Jaume

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278 Preclinical development of LYL119, a ROR1-targeted CAR T-cell product incorporating four novel T-cell reprogramming technologies to overcome barriers to effective cell therapy... von Lam, Viola C, Li, Aileen, Casas, Meritxell Galindo, Barragan, Jessica, Cheung, Christina, Briones, Jessica, Afreen, Esha, Vavra, Grant, Lu, Jia, Sundar, Purnima, Martinez, Rowena, Sims, Candace, Ta, Christina, Nigatu, Eskedar, Potluri, Shobha, Ali, Omar, Cheung, Alexander S, Lynn, Rachel C

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Location Matters: Site of Conjugation Modulates Stability and Pharmacokinetics of Antibody Drug Conjugates von Strop, Pavel, Liu, Shu-Hui, Dorywalska, Magdalena, Delaria, Kathy, Dushin, Russell G., Tran, Thomas-Toan, Ho, Wei-Hsien, Farias, Santiago, Casas, Meritxell Galindo, Abdiche, Yasmina, Zhou, Dahui, Chandrasekaran, Ramalakshmi, Samain, Caroline, Loo, Carole, Rossi, Andrea, Rickert, Mathias, Krimm, Stellanie, Wong, Teresa, Chin, Sherman Michael, Yu, Jessica, Dilley, Jeanette, Chaparro-Riggers, Javier, Filzen, Gary F., O’Donnell, Christopher J., Wang, Fang, Myers, Jeremy S., Pons, Jaume, Shelton, David L., Rajpal, Arvind

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Site-specific conjugation improves therapeutic index of antibody drug conjugates with high drug loading von Strop, Pavel, Delaria, Kathy, Foletti, Davide, Witt, Jody Melton, Hasa-Moreno, Adela, Poulsen, Kris, Casas, Meritxell Galindo, Dorywalska, Magdalena, Farias, Santiago, Pios, Ariel, Lui, Victor, Dushin, Russell, Zhou, Dahui, Navaratnam, Thayalan, Tran, Thomas-Toan, Sutton, Janette, Lindquist, Kevin C, Han, Bora, Liu, Shu-Hui, Shelton, David L, Pons, Jaume, Rajpal, Arvind

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Increasing Serum Half-life and Extending Cholesterol Lowering in Vivo by Engineering Antibody with pH-sensitive Binding to PCSK9 von Chaparro-Riggers, Javier, Liang, Hong, DeVay, Rachel M., Bai, Lanfang, Sutton, Janette E., Chen, Wei, Geng, Tao, Lindquist, Kevin, Casas, Meritxell Galindo, Boustany, Leila M., Brown, Colleen L., Chabot, Jeffrey, Gomes, Bruce, Garzone, Pamela, Rossi, Andrea, Strop, Pavel, Shelton, Dave, Pons, Jaume, Rajpal, Arvind

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Mechanism of Action and In Vivo Efficacy of a Human-Derived Antibody against Staphylococcus aureus α-Hemolysin von Foletti, Davide, Strop, Pavel, Shaughnessy, Lee, Hasa-Moreno, Adela, Casas, Meritxell Galindo, Russell, Marcella, Bee, Christine, Wu, Si, Pham, Amber, Zeng, Zhilan, Pons, Jaume, Rajpal, Arvind, Shelton, Dave

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370 The Epi-RTM technology produces a polyclonal TIL product (LYL845) with a greater expansion success rate across hot and cold tumors, improved product phenotype, and maintenance... von Patel, Yogin, Harris, Benjamin, Bedard, Melissa, Kritikou, Joanna, Meritxell Galindo Casas, Harms, Carson, DeFrancesco, Melissa, Sundar, Purnima, Restifo, Nicholas, Lee, Gary, Potluri, Shobha, Vodnala, Suman Kumar

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RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models von Wong, Oi Kwan, Tran, Thomas-Toan, Ho, Wei-Hsien, Casas, Meritxell Galindo, Au, Melinda, Bateman, Marjorie, Lindquist, Kevin C, Rajpal, Arvind, Shelton, David L, Strop, Pavel, Liu, Shu-Hui

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Mechanism of Action and In Vivo Efficacy of a Human-Derived Antibody against Staphylococcus aureus [alpha]-Hemolysin von Foletti, Davide, Strop, Pavel, Shaughnessy, Lee, Hasa-Moreno, Adela, Casas, Meritxell Galindo, Russell, Marcella, Bee, Christine, Wu, Si, Pham, Amber, Zeng, Zhilan, Pons, Jaume, Rajpal, Arvind, Shelton, Dave

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Modified caspase-9 polypeptides and methods of use thereof von GALINDO CASAS, Meritxell, VAN BLARCOM, Thomas John

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Modified caspase-9 polypeptides and methods of use thereof von Galindo Casas, Meritxell, Van Blarcom, Thomas John

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Modified caspase-9 polypeptides and methods of use thereof von GALINDO CASAS, Meritxell, VAN BLARCOM, Thomas John

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Modified caspase-9 polypeptides and methods of use thereof von GALINDO CASAS, Meritxell, VAN BLARCOM, Thomas John

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