Attenuation of miR-126 Activity Expands HSC In Vivo without Exhaustion von Lechman, Eric R., Gentner, Bernhard, van Galen, Peter, Giustacchini, Alice, Saini, Massimo, Boccalatte, Francesco E., Hiramatsu, Hidefumi, Restuccia, Umberto, Bachi, Angela, Voisin, Veronique, Bader, Gary D., Dick, John E., Naldini, Luigi

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Chromatin accessibility promotes hematopoietic and leukemia stem cell activity von Cabal-Hierro, Lucia, van Galen, Peter, Prado, Miguel A., Higby, Kelly J., Togami, Katsuhiro, Mowery, Cody T., Paulo, Joao A., Xie, Yingtian, Cejas, Paloma, Furusawa, Takashi, Bustin, Michael, Long, Henry W., Sykes, David B., Gygi, Steven P., Finley, Daniel, Bernstein, Bradley E., Lane, Andrew A.

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Extended-representation bisulfite sequencing of gene regulatory elements in multiplexed samples and single cells von Shareef, Sarah J., Bevill, Samantha M., Raman, Ayush T., Aryee, Martin J., van Galen, Peter, Hovestadt, Volker, Bernstein, Bradley E.

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miR-126 Regulates Distinct Self-Renewal Outcomes in Normal and Malignant Hematopoietic Stem Cells von Lechman, Eric R., Gentner, Bernhard, Ng, Stanley W.K., Schoof, Erwin M., van Galen, Peter, Kennedy, James A., Nucera, Silvia, Ciceri, Fabio, Kaufmann, Kerstin B., Takayama, Naoya, Dobson, Stephanie M., Trotman-Grant, Aaron, Krivdova, Gabriela, Elzinga, Janneke, Mitchell, Amanda, Nilsson, Björn, Hermans, Karin G., Eppert, Kolja, Marke, Rene, Isserlin, Ruth, Voisin, Veronique, Bader, Gary D., Zandstra, Peter W., Golub, Todd R., Ebert, Benjamin L., Lu, Jun, Minden, Mark, Wang, Jean C.Y., Naldini, Luigi, Dick, John E.

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Reduced Lymphoid Lineage Priming Promotes Human Hematopoietic Stem Cell Expansion von van Galen, Peter, Kreso, Antonija, Wienholds, Erno, Laurenti, Elisa, Eppert, Kolja, Lechman, Eric R., Mbong, Nathan, Hermans, Karin, Dobson, Stephanie, April, Craig, Fan, Jian-Bing, Dick, John E.

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Single-cell lineage analysis reveals genetic and epigenetic interplay in glioblastoma drug resistance von Eyler, Christine E, Matsunaga, Hironori, Hovestadt, Volker, Vantine, Samantha J, van Galen, Peter, Bernstein, Bradley E

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Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq von Filbin, Mariella G, Tirosh, Itay, Hovestadt, Volker, Shaw, McKenzie L, Escalante, Leah E, Mathewson, Nathan D, Neftel, Cyril, Frank, Nelli, Pelton, Kristine, Hebert, Christine M, Haberler, Christine, Yizhak, Keren, Gojo, Johannes, Egervari, Kristof, Mount, Christopher, van Galen, Peter, Bonal, Dennis M, Nguyen, Quang-De, Beck, Alexander, Sinai, Claire, Czech, Thomas, Dorfer, Christian, Goumnerova, Liliana, Lavarino, Cinzia, Carcaboso, Angel M, Mora, Jaume, Mylvaganam, Ravindra, Luo, Christina C, Peyrl, Andreas, Popović, Mara, Azizi, Amedeo, Batchelor, Tracy T, Frosch, Matthew P, Martinez-Lage, Maria, Kieran, Mark W, Bandopadhayay, Pratiti, Beroukhim, Rameen, Fritsch, Gerhard, Getz, Gad, Rozenblatt-Rosen, Orit, Wucherpfennig, Kai W, Louis, David N, Monje, Michelle, Slavc, Irene, Ligon, Keith L, Golub, Todd R, Regev, Aviv, Bernstein, Bradley E, Suvà, Mario L

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A cellular hierarchy framework for understanding heterogeneity and predicting drug response in acute myeloid leukemia von Zeng, Andy G. X., Bansal, Suraj, Jin, Liqing, Mitchell, Amanda, Chen, Weihsu Claire, Abbas, Hussein A., Chan-Seng-Yue, Michelle, Voisin, Veronique, van Galen, Peter, Tierens, Anne, Cheok, Meyling, Preudhomme, Claude, Dombret, Hervé, Daver, Naval, Futreal, P. Andrew, Minden, Mark D., Kennedy, James A., Wang, Jean C. Y., Dick, John E.

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A novel method for detecting the cellular stemness state in normal and leukemic human hematopoietic cells can predict disease outcome and drug sensitivity von Yassin, Muhammad, Aqaqe, Nasma, Yassin, Abed Alkader, van Galen, Peter, Kugler, Eitan, Bernstein, Bradley E., Koren-Michowitz, Maya, Canaani, Jonathan, Nagler, Arnon, Lechman, Eric R., Dick, John E., Wienholds, Erno, Izraeli, Shai, Milyavsky, Michael

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Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer von Kreso, Antonija, O'Brien, Catherine A., van Galen, Peter, Gan, Olga I., Notta, Faiyaz, Brown, Andrew M. K., Ng, Karen, Ma, Jing, Wienholds, Erno, Dunant, Cyrille, Pollett, Aaron, Gallinger, Steven, McPherson, John, Mullighan, Charles G., Shibata, Darryl, Dick, John E.

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Self-renewal as a therapeutic target in human colorectal cancer von Kreso, Antonija, van Galen, Peter, Pedley, Nicholas M, Lima-Fernandes, Evelyne, Frelin, Catherine, Davis, Thomas, Cao, Liangxian, Baiazitov, Ramil, Du, Wu, Sydorenko, Nadiya, Moon, Young-Choon, Gibson, Lianne, Wang, Yadong, Leung, Cherry, Iscove, Norman N, Arrowsmith, Cheryl H, Szentgyorgyi, Eva, Gallinger, Steven, Dick, John E, O'Brien, Catherine A

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Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms von Kleppe, Maria, Koche, Richard, Zou, Lihua, van Galen, Peter, Hill, Corinne E., Dong, Lauren, De Groote, Sofie, Papalexi, Efthymia, Hanasoge Somasundara, Amritha V., Cordner, Keith, Keller, Matthew, Farnoud, Noushin, Medina, Juan, McGovern, Erin, Reyes, Jaime, Roberts, Justin, Witkin, Matthew, Rapaport, Franck, Teruya-Feldstein, Julie, Qi, Jun, Rampal, Raajit, Bernstein, Bradley E., Bradner, James E., Levine, Ross L.

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“Candidatus Hydrogenisulfobacillus filiaventi” strain R50 gen. nov. sp. nov., a highly efficient producer of extracellular organic compounds from H2 and CO2 von Hogendoorn, Carmen, Pol, Arjan, de Graaf, Rob, White, Paul B., Mesman, Rob, van Galen, Peter M., van Alen, Theo A., Cremers, Geert, Jansen, Robert S., Jetten, Mike S. M., Op den Camp, Huub J. M.

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Combination of Pantothenamides with Vanin Inhibitors as a Novel Antibiotic Strategy against Gram-Positive Bacteria von JANSEN, Patrick A. M, HERMKENS, Pedro H. H, ZEEUWEN, Patrick L. J. M, BOTMAN, Peter N. M, BLAAUW, Richard H, BURGHOUT, Peter, VAN GALEN, Peter M, MOUTON, Johan W, RUTJES, Floris P. J. T, SCHALKWIJK, Joost

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Isolation and identification of 4-α-rhamnosyloxy benzyl glucosinolate in Noccaea caerulescens showing intraspecific variation von de Graaf, Rob M., Krosse, Sebastian, Swolfs, Ad E.M., te Brinke, Esra, Prill, Nadine, Leimu, Roosa, van Galen, Peter M., Wang, Yanli, Aarts, Mark G.M., van Dam, Nicole M.

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EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression von Renneville, Aline, Van Galen, Peter, Canver, Matthew C., McConkey, Marie, Krill-Burger, John M., Dorfman, David M., Holson, Edward B., Bernstein, Bradley E., Orkin, Stuart H., Bauer, Daniel E., Ebert, Benjamin L.

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Dual Targeting of Oncogenic Activation and Inflammatory Signaling Increases Therapeutic Efficacy in Myeloproliferative Neoplasms von Kleppe, Maria, Koche, Richard, Zou, Lihua, van Galen, Peter, Hill, Corinne E., Dong, Lauren, De Groote, Sofie, Papalexi, Efthymia, Hanasoge Somasundara, Amritha V., Cordner, Keith, Keller, Matthew, Farnoud, Noushin, Medina, Juan, McGovern, Erin, Reyes, Jaime, Roberts, Justin, Witkin, Matthew, Rapaport, Franck, Teruya-Feldstein, Julie, Qi, Jun, Rampal, Raajit, Bernstein, Bradley E., Bradner, James E., Levine, Ross L.

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Chromatin complex dependencies reveal targeting opportunities in leukemia von Najm, Fadi J., DeWeirdt, Peter, Moore, Molly M., Bevill, Samantha M., El Farran, Chadi A., Macias, Kevin A., Hegde, Mudra, Waterbury, Amanda L., Liau, Brian B., van Galen, Peter, Doench, John G., Bernstein, Bradley E.

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Clonal barcoding with qPCR detection enables live cell functional analyses for cancer research von Guo, Qiuchen, Spasic, Milos, Maynard, Adam G., Goreczny, Gregory J., Bizuayehu, Amanuel, Olive, Jessica F., van Galen, Peter, McAllister, Sandra S.

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Decoding the Noncoding Cancer Genome von van Galen, Peter

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