The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases von BOHREN, K. M, BULLOCK, B, WERMUTH, B, GABBAY, K. H

Volltext

An Unlikely Sugar Substrate Site in the 1.65 Å Structure of the Human Aldose Reductase Holoenzyme Implicated in Diabetic Complications von Wilson, David K., Bohren, Kurt M., Gabbay, Kenneth H., Quiocho, Florante A.

Volltext

Retinal circulatory abnormalities in type 1 diabetes von Feke, GT, Buzney, SM, Ogasawara, H, Fujio, N, Goger, DG, Spack, NP, Gabbay, KH

Volltext

Tyrosine-48 Is the Proton Donor and Histidine-110 Directs Substrate Stereochemical Selectivity in the Reduction Reaction of Human Aldose Reductase: Enzyme Kinetics and Crystal Stru... von Bohren, Kurt M, Grimshaw, Charles E, Lai, Chung Jeng, Harrison, David H, Ringe, Dagmar, Petsko, Gregory A, Gabbay, Kenneth H

Volltext

An Anion Binding Site in Human Aldose Reductase: Mechanistic Implications for the Binding of Citrate, Cacodylate, and Glucose 6-Phosphate von Harrison, David H, Bohren, Kurt M, Ringe, Dagmar, Petsko, Gregory A, Gabbay, Kenneth H

Volltext

Characterization of the Osmotic Response Element of the Human Aldose Reductase Gene Promoter von Ruepp, Barbara, Bohren, Kurt M., Gabbay, Kenneth H.

Volltext

Catalytic effectiveness of human aldose reductase. Critical role of C-terminal domain von BOHREN, KM, GRIMSHAW, CE, GABBAY, KH

Volltext

Characterization of the human aldose reductase gene promoter von Wang, K, Bohren, K M, Gabbay, K H

Volltext

Expression of human aldose and aldehyde reductases. Site-directed mutagenesis of a critical lysine 262 von BOHREN, K. M, PAGE, J. L, SHANKAR, R, HENRY, S. P, GABBAY, K. H

Volltext

Human carbonyl reductase. Nucleotide sequence analysis of a cDNA and amino acid sequence of the encoded protein von Wermuth, B, Bohren, K M, Heinemann, G, von Wartburg, J P, Gabbay, K H

Volltext

Characterization of the Human Aldehyde Reductase Gene and Promoter von Barski, Oleg A., Gabbay, Kenneth H., Bohren, Kurt M.

Volltext

Linkage of the VNTR/insulin-gene and type I diabetes mellitus : increased gene sharing in affected sibling pairs von OWERBACH, D, GABBAY, K. H

Volltext

Identification and Characterization of Multiple Osmotic Response Sequences in the Human Aldose Reductase Gene von Ko, Ben C.B., Ruepp, Barbara, Bohren, Kurt M., Gabbay, Kenneth H., Chung, Stephen S.M.

Volltext

Secretion of an insulin-like growth factor-I-related protein by human breast cancer cells von HUFF, K. K, KAUFMAN, D, GABBAY, K. H, SPENCER, E. M, LIPPMAN, M. E, DICKSON, R. B

Volltext

Growth hormone regulates the abundance of insulin-like growth factor I RNA in adult rat liver von Roberts, C T, Brown, A L, Graham, D E, Seelig, S, Berry, S, Gabbay, K H, Rechler, M M

Volltext

Osmotic response element enhancer activity. Regulation through p38 kinase and mitogen-activated extracellular signal-regulated kinase kinase von Nadkarni, V, Gabbay, K H, Bohren, K M, Sheikh-Hamad, D

Volltext

Cyclosporine A inhibits the adaptive responses to hypertonicity: A potential mechanism of nephrotoxicity von SHEIKH-HAMAD, David, NADKARNI, Varsha, CHOI, Yeong-Jin, TRUONG, Luan D, WIDEMAN, Christi, HODJATI, Ramin, GABBAY, Kenneth H

Volltext

Mechanism of Human Aldehyde Reductase: Characterization of the Active Site Pocket von Barski, Oleg A, Gabbay, Kenneth H, Grimshaw, Charles E, Bohren, Kurt M

Volltext

Human Aldose Reductase: Rate Constants for a Mechanism Including Interconversion of Ternary Complexes by Recombinant Wild-Type Enzyme von Grimshaw, Charles E, Bohren, Kurt M, Lai, Chung-Jeng, Gabbay, Kenneth H

Volltext

A M55V Polymorphism in a Novel SUMO Gene (SUMO-4) Differentially Activates Heat Shock Transcription Factors and Is Associated with Susceptibility to Type I Diabetes Mellitus von Bohren, Kurt M., Nadkarni, Varsha, Song, Jian H., Gabbay, Kenneth H., Owerbach, David

Volltext