Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis von Kwiatkowski, T.J. Jr, Bosco, D.A, LeClerc, A.L, Tamrazian, E, Vanderburg, C.R, Russ, C, Davis, A, Gilchrist, J, Kasarskis, E.J, Munsat, T, Valdmanis, P, Rouleau, G.A, Hosler, B.A, Cortelli, P, de Jong, P.J, Yoshinaga, Y, Haines, J.L, Pericak-Vance, M.A, Yan, J, Ticozzi, N, Siddique, T, McKenna-Yasek, D, Sapp, P.C, Horvitz, H.R, Landers, J.E, Brown, R.H. Jr

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Neurons derived from patients with bipolar disorder divide into intrinsically different sub-populations of neurons, predicting the patients’ responsiveness to lithium von Stern, S, Santos, R, Marchetto, M C, Mendes, A P D, Rouleau, G A, Biesmans, S, Wang, Q-W, Yao, J, Charnay, P, Bang, A G, Alda, M, Gage, F H

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Contribution of TARDBP mutations to sporadic amyotrophic lateral sclerosis von Daoud, H, Valdmanis, P N, Kabashi, E, Dion, P, Dupré, N, Camu, W, Meininger, V, Rouleau, G A

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Systematic resequencing of X-chromosome synaptic genes in autism spectrum disorder and schizophrenia von Piton, A, Gauthier, J, Hamdan, F F, Lafrenière, R G, Yang, Y, Henrion, E, Laurent, S, Noreau, A, Thibodeau, P, Karemera, L, Spiegelman, D, Kuku, F, Duguay, J, Destroismaisons, L, Jolivet, P, Côté, M, Lachapelle, K, Diallo, O, Raymond, A, Marineau, C, Champagne, N, Xiong, L, Gaspar, C, Rivière, J-B, Tarabeux, J, Cossette, P, Krebs, M-O, Rapoport, J L, Addington, A, DeLisi, L E, Mottron, L, Joober, R, Fombonne, E, Drapeau, P, Rouleau, G A

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A novel frameshift mutation in UPF3B identified in brothers affected with childhood onset schizophrenia and autism spectrum disorders von Addington, A M, Gauthier, J, Piton, A, Hamdan, F F, Raymond, A, Gogtay, N, Miller, R, Tossell, J, Bakalar, J, Germain, G, Gochman, P, Long, R, Rapoport, J L, Rouleau, G A

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Alpha galactosidase A activity in Parkinson's disease von Alcalay, R.N., Wolf, P., Levy, O.A., Kang, U.J., Waters, C., Fahn, S., Ford, B., Kuo, S.H., Vanegas, N., Shah, H., Liong, C., Narayan, S., Pauciulo, M.W., Nichols, W.C., Gan-Or, Z., Rouleau, G.A., Chung, W.K., Oliva, P., Keutzer, J., Marder, K., Zhang, X.K.

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Rare susceptibility variants for bipolar disorder suggest a role for G protein-coupled receptors von Cruceanu, C, Schmouth, J-F, Torres-Platas, S G, Lopez, J P, Ambalavanan, A, Darcq, E, Gross, F, Breton, B, Spiegelman, D, Rochefort, D, Hince, P, Petite, J M, Gauthier, J, Lafrenière, R G, Dion, P A, Greenwood, C M, Kieffer, B L, Alda, M, Turecki, G, Rouleau, G A

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Patterns of gene expression in the limbic system of suicides with and without major depression von Sequeira, A, Klempan, T, Canetti, L, ffrench-Mullen, J, Benkelfat, C, Rouleau, G A, Turecki, G

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Rare mutations in N-methyl-D-aspartate glutamate receptors in autism spectrum disorders and schizophrenia von Tarabeux, J, Kebir, O, Gauthier, J, Hamdan, F F, Xiong, L, Piton, A, Spiegelman, D, Henrion, É, Millet, B, Fathalli, F, Joober, R, Rapoport, J L, DeLisi, L E, Fombonne, É, Mottron, L, Forget-Dubois, N, Boivin, M, Michaud, J L, Drapeau, P, Lafrenière, R G, Rouleau, G A, Krebs, M-O

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Mutations in FUS cause FALS and SALS in French and French Canadian populations von BELZIL, V. V, VALDMANIS, P. N, LACOMBLEZ, L, SALACHAS, F, PRADAT, P.-F, CAMU, W, MEININGER, V, DUPRE, N, ROULEAU, G. A, DION, P. A, DAOUD, H, KABASHI, E, NOREAU, A, GAUTHIER, J, HINCE, P, DESJARLAIS, A, BOUCHARD, J.-P

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Phenotype and genotype analysis in amyotrophic lateral sclerosis with TARDBP gene mutations von CORCIA, P, VALDMANIS, P, DANEL-BRUNAUD, V, VANDENBERGHE, N, PRADAT, P. F, COURATIER, P, SALACHAS, F, LUMBROSO, S, ROULEAU, G. A, MEININGER, V, CAMU, W, MILLECAMPS, S, LIONNET, C, BLASCO, H, MOUZAT, K, DAOUD, H, BELZIL, V, MORALES, R, PAGEOT, N

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Loss of the proprioception and touch sensation channel PIEZO2 in siblings with a progressive form of contractures von Mahmud, A.A., Nahid, N.A., Nassif, C., Sayeed, M.S.B., Ahmed, M.U., Parveen, M., Khalil, M.I., Islam, M.M., Nahar, Z., Rypens, F., Hamdan, F.F., Rouleau, G.A., Hasnat, A., Michaud, J.L.

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Novel integrative genomic tool for interrogating lithium response in bipolar disorder von Hunsberger, J G, Chibane, F L, Elkahloun, A G, Henderson, R, Singh, R, Lawson, J, Cruceanu, C, Nagarajan, V, Turecki, G, Squassina, A, Medeiros, C D, Del Zompo, M, Rouleau, G A, Alda, M, Chuang, D-M

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A homozygous mutation in SLC1A4 in siblings with severe intellectual disability and microcephaly von Srour, M., Hamdan, F. F., Gan-Or, Z., Labuda, D., Nassif, C., Oskoui, M., Gana-Weisz, M., Orr-Urtreger, A., Rouleau, G.A., Michaud, J.L.

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The location of constitutional neurofibromatosis 2 (NF2) splice site mutations is associated with the severity of NF2 von Baser, M E, Kuramoto, L, Woods, R, Joe, H, Friedman, J M, Wallace, A J, Ramsden, R T, Olschwang, S, Bijlsma, E, Kalamarides, M, Papi, L, Kato, R, Carroll, J, Lázaro, C, Joncourt, F, Parry, D M, Rouleau, G A, Evans, D G R

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A novel autosomal dominant restless legs syndrome locus maps to chromosome 20p13 von LEVCHENKO, A, PROVOST, S, ROULEAU, G. A, MONTPLAISIR, J.-Y, XIONG, L, ST-ONGE, J, THIBODEAU, P, RIVIERE, J.-B, DESAUTELS, A, TURECKI, G, DUBE, M.-P

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Canadian restless legs syndrome twin study von XIONG, L, JANG, K, MONTPLAISIR, J, LEVCHENKO, A, THIBODEAU, P, GASPAR, C, TURECKI, G, ROULEAU, G. A

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Administration of testosterone results in reversible deterioration in Kennedy’s disease von Kinirons, P, Rouleau, G A

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Evidence for a genetic association between monoamine oxidase A and restless legs syndrome von DESAUTELS, A, TURECKI, G, MONTPLAISIR, J, BRISEBOIS, K, SEQUEIRA, A, ADAM, B, ROULEAU, G. A

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Posttranslational modifications & lithium’s therapeutic effect—Potential biomarkers for clinical responses in psychiatric & neurodegenerative disorders von Khayachi, A., Schorova, L., Alda, M., Rouleau, G.A., Milnerwood, A.J.

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