A microRNA miR-34a-Regulated Bimodal Switch Targets Notch in Colon Cancer Stem Cells von Bu, Pengcheng, Chen, Kai-Yuan, Chen, Joyce Huan, Wang, Lihua, Walters, Jewell, Shin, Yong Jun, Goerger, Julian P., Sun, Jian, Witherspoon, Mavee, Rakhilin, Nikolai, Li, Jiahe, Yang, Herman, Milsom, Jeff, Lee, Sang, Zipfel, Warren, Jin, Moonsoo M., Gümüş, Zeynep H., Lipkin, Steven M., Shen, Xiling

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SCLC: Epidemiology, Risk Factors, Genetic Susceptibility, Molecular Pathology, Screening, and Early Detection von Wang, Qian, Gümüş, Zeynep H., Colarossi, Cristina, Memeo, Lorenzo, Wang, Xintong, Kong, Chung Yin, Boffetta, Paolo

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A Machine Learning Approach for Hot-Spot Detection at Protein-Protein Interfaces von Melo, Rita, Fieldhouse, Robert, Melo, André, Correia, João D G, Cordeiro, Maria Natália D S, Gümüş, Zeynep H, Costa, Joaquim, Bonvin, Alexandre M J J, Moreira, Irina S

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Comparative effects of oncogenic mutations G12C, G12V, G13D, and Q61H on local conformations and dynamics of K-Ras von Vatansever, Sezen, Erman, Burak, Gümüş, Zeynep H.

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Integrative Annotation of Variants from 1092 Humans: Application to Cancer Genomics von Khurana, Ekta, Fu, Yao, Colonna, Vincenza, Mu, Xinmeng Jasmine, Kang, Hyun Min, Lappalainen, Tuuli, Sboner, Andrea, Lochovsky, Lucas, Chen, Jieming, Harmanci, Arif, Das, Jishnu, Abyzov, Alexej, Balasubramanian, Suganthi, Beal, Kathryn, Chakravarty, Dimple, Challis, Daniel, Chen, Yuan, Clarke, Declan, Clarke, Laura, Cunningham, Fiona, Evani, Uday S., Flicek, Paul, Fragoza, Robert, Garrison, Erik, Gibbs, Richard, Gümüş, Zeynep H., Herrero, Javier, Kitabayashi, Naoki, Kong, Yong, Lage, Kasper, Liluashvili, Vaja, Lipkin, Steven M., MacArthur, Daniel G., Marth, Gabor, Muzny, Donna, Pers, Tune H., Ritchie, Graham R. S., Rosenfeld, Jeffrey A., Sisu, Cristina, Wei, Xiaomu, Wilson, Michael, Xue, Yali, Yu, Fuli, Dermitzakis, Emmanouil T., Yu, Haiyuan, Rubin, Mark A., Tyler-Smith, Chris, Gerstein, Mark

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SpotOn: High Accuracy Identification of Protein-Protein Interface Hot-Spots von Moreira, Irina S., Koukos, Panagiotis I., Melo, Rita, Almeida, Jose G., Preto, Antonio J., Schaarschmidt, Joerg, Trellet, Mikael, Gümüş, Zeynep H., Costa, Joaquim, Bonvin, Alexandre M. J. J.

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Rare, Pathogenic Germline Variants in Fanconi Anemia Genes Increase Risk for Squamous Lung Cancer von Esai Selvan, Myvizhi, Klein, Robert J, Gümüş, Zeynep H

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ProNetView‐ccRCC: A Web‐Based Portal to Interactively Explore Clear Cell Renal Cell Carcinoma Proteogenomics Networks von Kalayci, Selim, Petralia, Francesca, Wang, Pei, Gümüş, Zeynep H.

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Structural and Spectroscopic Characterization of 3-[4-(Trifluoromethyl)Phenyl]-3a,4,8,8a-Tetrahydro-6H-[1,3] Dioxepino[5,6-d][1,2]Oxazole Compound: An Experimental and Density Func... von Gümüş, H., Tekin, N., Kara, Y. S.

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Comprehensive Immunoprofiling of Pediatric Zika Reveals Key Role for Monocytes in the Acute Phase and No Effect of Prior Dengue Virus Infection von Michlmayr, Daniela, Kim, Eun-Young, Rahman, Adeeb H., Raghunathan, Rohit, Kim-Schulze, Seunghee, Che, Yan, Kalayci, Selim, Gümüş, Zeynep H., Kuan, Guillermina, Balmaseda, Angel, Kasarskis, Andrew, Wolinsky, Steven M., Suaréz-Fariñas, Mayte, Harris, Eva

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Novel ultra-rare exonic variants identified in a founder population implicate cadherins in schizophrenia von Lencz, Todd, Yu, Jin, Khan, Raiyan Rashid, Flaherty, Erin, Carmi, Shai, Lam, Max, Ben-Avraham, Danny, Barzilai, Nir, Bressman, Susan, Darvasi, Ariel, Cho, Judy H., Clark, Lorraine N., Gümüş, Zeynep H., Vijai, Joseph, Klein, Robert J., Lipkin, Steven, Offit, Kenneth, Ostrer, Harry, Ozelius, Laurie J., Peter, Inga, Malhotra, Anil K., Maniatis, Tom, Atzmon, Gil, Pe’er, Itsik

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A Brave New World: Virtual Reality and Augmented Reality in Systems Biology von Turhan, Berk, Gümüş, Zeynep H

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Whole-brain resting-state connectivity underlying impaired inhibitory control during early versus longer-term abstinence in cocaine addiction von Zilverstand, Anna, Parvaz, Muhammad A., Moeller, Scott J., Kalayci, Selim, Kundu, Prantik, Malaker, Pias, Alia-Klein, Nelly, Gümüş, Zeynep H., Goldstein, Rita Z.

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Ancestral reconstruction reveals mechanisms of ERK regulatory evolution von Sang, Dajun, Pinglay, Sudarshan, Wiewiora, Rafal P, Selvan, Myvizhi E, Lou, Hua Jane, Chodera, John D, Turk, Benjamin E, Gümüş, Zeynep H, Holt, Liam J

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Are polygenic risk scores ready for the cancer clinic?—a perspective von Klein, Robert J., Gümüş, Zeynep H.

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SNPs at SMG7 Associated with Time from Biochemical Recurrence to Prostate Cancer Death von Song, Xiaoyu, Ru, Meng, Steinsnyder, Zoe, Tkachuk, Kaitlyn, Kopp, Ryan P, Sullivan, John, Gümüş, Zeynep H, Offit, Kenneth, Joseph, Vijai, Klein, Robert J

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Ancestry-specific predisposing germline variants in cancer von Oak, Ninad, Cherniack, Andrew D., Mashl, R. Jay, Hirsch, Fred R., Ding, Li, Beroukhim, Rameen, Gumus, Zeynep H., Plon, Sharon E., Huang, Kuan-lin

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An immunogenetic basis for lung cancer risk von Krishna, Chirag, Tervi, Anniina, Saffern, Miriam, Wilson, Eric A, Yoo, Seong-Keun, Mars, Nina, Roudko, Vladimir, Cho, Byuri Angela, Jones, Samuel Edward, Vaninov, Natalie, Selvan, Myvizhi Esai, Gümüş, Zeynep H, Lenz, Tobias L, Merad, Miriam, Boffetta, Paolo, Martínez-Jiménez, Francisco, Ollila, Hanna M, Samstein, Robert M, Chowell, Diego

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ImmuneRegulation: a web-based tool for identifying human immune regulatory elements von Kalayci, Selim, Selvan, Myvizhi Esai, Ramos, Irene, Cotsapas, Chris, Harris, Eva, Kim, Eun-Young, Montgomery, Ruth R, Poland, Gregory, Pulendran, Bali, Tsang, John S, Klein, Robert J, Gümüş, Zeynep H

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A unique serum IgG glycosylation signature predicts development of Crohn’s disease and is associated with pathogenic antibodies to mannose glycan von Gaifem, Joana, Rodrigues, Cláudia S., Petralia, Francesca, Alves, Inês, Leite-Gomes, Eduarda, Cavadas, Bruno, Dias, Ana M., Moreira-Barbosa, Catarina, Revés, Joana, Laird, Renee M., Novokmet, Mislav, Štambuk, Jerko, Habazin, Siniša, Turhan, Berk, Gümüş, Zeynep H., Ungaro, Ryan, Torres, Joana, Lauc, Gordan, Colombel, Jean-Frederic, Porter, Chad K., Pinho, Salomé S.

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