Diarylquinolines Are Bactericidal for Dormant Mycobacteria as a Result of Disturbed ATP Homeostasis von Koul, Anil, Vranckx, Luc, Dendouga, Najoua, Balemans, Wendy, Van den Wyngaert, Ilse, Vergauwen, Karen, Göhlmann, Hinrich W.H., Willebrords, Rudy, Poncelet, Alain, Guillemont, Jerome, Bald, Dirk, Andries, Koen

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Transcriptional Characterization of Compounds: Lessons Learned from the Public LINCS Data von De Wolf, Hans, De Bondt, An, Turner, Heather, Göhlmann, Hinrich W H

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Diarylquinoline Drug Active on the ATP Synthase of Mycobacterium tuberculosis von Andries, Koen, Verhasselt, Peter, Guillemont, Jerome, Göhlmann, Hinrich W. H, Neefs, Jean-Marc, Winkler, Hans, Van Gestel, Jef, Timmerman, Philip, Zhu, Min, Lee, Ennis, Williams, Peter, de Chaffoy, Didier, Huitric, Emma, Hoffner, Sven, Cambau, Emmanuelle, Truffot-Pernot, Chantal, Lounis, Nacer, Jarlier, Vincent

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Using transcriptomics to guide lead optimization in drug discovery projects: Lessons learned from the QSTAR project von Verbist, Bie, Klambauer, Günter, Vervoort, Liesbet, Talloen, Willem, Shkedy, Ziv, Thas, Olivier, Bender, Andreas, Göhlmann, Hinrich W.H., Hochreiter, Sepp

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Alterations in Mucosal Immunity Identified in the Colon of Patients With Irritable Bowel Syndrome von Aerssens, Jeroen, Camilleri, Michael, Talloen, Willem, Thielemans, Leen, Göhlmann, Hinrich W.H, Van den Wyngaert, Ilse, Thielemans, Theo, De Hoogt, Ronald, Andrews, Christopher N, Bharucha, Adil E, Carlson, Paula J, Busciglio, Irene, Burton, Duane D, Smyrk, Thomas, Urrutia, Raul, Coulie, Bernard

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Analysis of Affymetrix GeneChip® data using amplified RNA von Cope, Leslie, Hartman, Scott M, Göhlmann, Hinrich W.H, Tiesman, Jay P, Irizarry, Rafael A

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Response prediction to a multitargeted kinase inhibitor in cancer cell lines and xenograft tumors using high-content tyrosine peptide arrays with a kinetic readout von Versele, Matthias, Talloen, Willem, Rockx, Cindy, Geerts, Tamara, Janssen, Boud, Lavrijssen, Tom, King, Peter, Göhlmann, Hinrich W H, Page, Martin, Perera, Tim

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Delayed bactericidal response of Mycobacterium tuberculosis to bedaquiline involves remodelling of bacterial metabolism von Koul, Anil, Vranckx, Luc, Dhar, Neeraj, Göhlmann, Hinrich W.H., Özdemir, Emre, Neefs, Jean-Marc, Schulz, Melanie, Lu, Ping, Mørtz, Ejvind, McKinney, John D., Andries, Koen, Bald, Dirk

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FABIA: factor analysis for bicluster acquisition von Hochreiter, Sepp, Bodenhofer, Ulrich, Heusel, Martin, Mayr, Andreas, Mitterecker, Andreas, Kasim, Adetayo, Khamiakova, Tatsiana, Van Sanden, Suzy, Lin, Dan, Talloen, Willem, Bijnens, Luc, Göhlmann, Hinrich W. H., Shkedy, Ziv, Clevert, Djork-Arné

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Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines von Cox, Michael J., Jaensch, Steffen, Van de Waeter, Jelle, Cougnaud, Laure, Seynaeve, Daan, Benalla, Soulaiman, Koo, Seong Joo, Van Den Wyngaert, Ilse, Neefs, Jean-Marc, Malkov, Dmitry, Bittremieux, Mart, Steemans, Margino, Peeters, Pieter J., Wegner, Jörg Kurt, Ceulemans, Hugo, Gustin, Emmanuel, Chong, Yolanda T., Göhlmann, Hinrich W. H.

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beadarrayFilter: An R Package to Filter Beads von Forcheh, Anyiawung,Chiara, Verbeke, Geert, Kasim, Adetayo, Lin, Dan, Shkedy, Ziv, Talloen, Willem, Göhlmann, Hinrich,W.H., Clement, Lieven

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Testing for Trends in Dose-Response Microarray Experiments: A Comparison of Several Testing Procedures, Multiplicity and Resampling-Based Inference von Lin, Dan, Shkedy, Ziv, Yekutieli, Dani, Burzykowski, Tomasz, Göhlmann, Hinrich W.H., De Bondt, An, Perera, Tim, Geerts, Tamara, Bijnens, Luc

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I/NI-calls for the exclusion of non-informative genes: a highly effective filtering tool for microarray data von Talloen, Willem, Clevert, Djork-Arné, Hochreiter, Sepp, Amaratunga, Dhammika, Bijnens, Luc, Kass, Stefan, Göhlmann, Hinrich W.H.

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Integrating High-Dimensional Transcriptomics and Image Analysis Tools into Early Safety Screening: Proof of Concept for a New Early Drug Development Strategy von Verbist, Bie M. P, Verheyen, Geert R, Vervoort, Liesbet, Crabbe, Marjolein, Beerens, Dominiek, Bosmans, Cindy, Jaensch, Steffen, Osselaer, Steven, Talloen, Willem, Van den Wyngaert, Ilse, Van Hecke, Geert, Wuyts, Dirk, Van Goethem, Freddy, Göhlmann, Hinrich W. H

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Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis von Ravindranath, Aakash Chavan, Perualila-Tan, Nolen, Kasim, Adetayo, Drakakis, Georgios, Liggi, Sonia, Brewerton, Suzanne C, Mason, Daniel, Bodkin, Michael J, Evans, David A, Bhagwat, Aditya, Talloen, Willem, Göhlmann, Hinrich W H, Shkedy, Ziv, Bender, Andreas

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A joint modeling approach for uncovering associations between gene expression, bioactivity and chemical structure in early drug discovery to guide lead selection and genomic biomar... von Perualila-Tan, Nolen, Kasim, Adetayo, Talloen, Willem, Verbist, Bie, Göhlmann, Hinrich W.H., QSTAR Consortium, Shkedy, Ziv

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Understanding drugs in breast cancer through drug sensitivity screening von Uhr, Katharina, Prager-van der Smissen, Wendy J. C., Heine, Anouk A. J., Ozturk, Bahar, Smid, Marcel, Göhlmann, Hinrich W. H., Jager, Agnes, Foekens, John A., Martens, John W. M.

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The high-level similarity of some disparate gene expression measures von Raghavan, Nandini, De Bondt, An M. I. M., Talloen, Willem, Moechars, Dieder, Göhlmann, Hinrich W. H., Amaratunga, Dhammika

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Abstract 115: An integrated framework of transcriptome analysis leads to mechanistic insights into the FTI/Taxol synergy von Gjyrezi, Ada, Gümüş, Zeynep H., Van den Wyngaert, Ilse, Talloen, William, Göhlmann, Hinrich W.H., Weinstein, Harel, Giannakakou, Paraskevi

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Genomic Biomarkers for a Binary Clinical Outcome in Early Drug Development Microarray Experiments von Van Sanden, Suzy, Shkedy, Ziv, Burzykowski, Tomasz, Göhlmann, Hinrich W. H., Talloen, Willem, Bijnens, Luc

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