Familial Clustering of Erosive Hand Osteoarthritis in a Large Statewide Cohort von Kazmers, Nikolas H., Meeks, Huong D., Novak, Kendra A., Yu, Zhe, Fulde, Gail L., Thomas, Joy L., Barker, Tyler, Jurynec, Michael J.

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Germline variants of ATG7 in familial cholangiocarcinoma alter autophagy and p62 von Greer, Stephanie U., Chen, Jiamin, Ogmundsdottir, Margret H., Ayala, Carlos, Lau, Billy T., Delacruz, Richard Glenn C., Sandoval, Imelda T., Kristjansdottir, Sigrun, Jones, David A., Haslem, Derrick S., Romero, Robin, Fulde, Gail, Bell, John M., Jonasson, Jon G., Steingrimsson, Eirikur, Ji, Hanlee P., Nadauld, Lincoln D.

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An elevated neutrophil-to-lymphocyte ratio associates with weight loss and cachexia in cancer von Barker, Tyler, Fulde, Gail, Moulton, Bryce, Nadauld, Lincoln D., Rhodes, Terence

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Immune related biomarkers in biliary tract cancers (BTC) von Sandhu, Zoya, Sanchez-Garcia, Jorge, Barker, Tyler, Raghunath, Sharanya, Shortt, Katherine, Hwang, Su-Ho, Fulde, Gail, Zendejas-Ruiz, Ivan R, Haslem, Derrick S., Yeatman, Timothy Joseph, Thota, Ramya

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62 Identify immune cell types and biomarkers associated with immune-related adverse events using single cell RNA sequencing von Chen, Jiamin, Pflieger, Lance, Grimes, Sue, Baker, Tyler, Brems, Michael, Fulde, Gail, Snow, Shawnee, Howe, Parker, Sathe, Anuja, Christensen, Bryce, Ji, Hanlee, Rhodes, Terence

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Evaluation of multiple myeloma clinical decision support tool value for assessing treatment selection variation when populated with community health system data von Labkoff, Steven E., Wilcox, Ryan Eldredge, Smith, Ben, Haslem, Derrick S., Hoda, Daanish, Fulde, Gail, Gygi, Jesse, Kennedy, Levi

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Evaluation of Multiple Myeloma Clinical Decision Support Tool Value When Populated with Community Health System Data von Labkoff, Steven E., Giusti, Kathy E., Giusti, Paul A., Wilcox, Ryan, Haslem, Derrick, Hoda, Daanish, Rowe, Kerry, Fulde, Gail, Gygi, Jesse, Bott, Brad, Smith, Ben

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Characterization of the tumor mutation burden in hepatobiliary tumors von Thota, Ramya, Christensen, Bryce, Fulde, Gail, Lewis, Mark Andrew, Haslem, Derrick S., Rhodes, Terence Duane, Nadauld, Lincoln, Barker, Tyler

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Universal Germline Testing of Unselected Cancer Patients Detects Pathogenic Variants Missed by Standard Guidelines without Increasing Healthcare Costs von Perkins, Adrienne T., Haslem, Derrick, Goldsberry, Jessica, Shortt, Katherine, Sittig, Laura, Raghunath, Sharanya, Giauque, Christopher, Snow, Shawnee, Fulde, Gail, Moulton, Bryce, Jones, David, Nadauld, Lincoln

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Cell cycle checkpoint defects in gastrointestinal malignancies von Thota, Ramya, Lewis, Mark Andrew, Nadauld, Lincoln, Haslem, Derrick S., Rhodes, Terence Duane, Christensen, Bryce, Fulde, Gail, Abraham, Tyler, Romero, Robin, Moulton, Bryce, Raghunath, Sharanya, Barker, Tyler

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Mutational landscape of metastatic colorectal cancer: Aggregate insights from a molecular tumor board von Lewis, Mark Andrew, Haslem, Derrick S., Thota, Ramya, Rhodes, Terence Duane, Barker, Tyler, Moulton, Bryce, Abraham, Tyler, Fulde, Gail, Romero, Robin, Christensen, Bryce, Nadauld, Lincoln

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DNA damage repair (DDR) pathway defects in gastrointestinal (GI) malignancies von Thota, Ramya, Fulde, Gail, Lewis, Mark Andrew, Haslem, Derrick S., Nadauld, Lincoln, Moulton, Bryce, Romero, Robin, Abraham, Tyler, Christensen, Bryce, Raghunath, Sharanya, Barker, Tyler

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Utility of next-generation sequencing in clinical decision making in hepatocellular carcinoma (HCC) von Thota, Ramya, Lewis, Mark Andrew, Raghunath, Sharanya, Haslem, Derrick S., Nadauld, Lincoln, Rhodes, Terence Duane, Moulton, Bryce, Abraham, Tyler, Romero, Robin, Fulde, Gail, Christensen, Bryce, Barker, Tyler

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Association of the neutrophil-to-lymphocyte ratio prior to checkpoint blockade immunotherapy (CBI) or radiation plus CBI with overall survival in melanoma patients von Rhodes, Terence Duane, Fulde, Gail, Romero, Robin, Abraham, Tyler, Moulton, Bryce, Van Meter, Margaret, Thota, Ramya, Lewis, Mark Andrew, Haslem, Derrick S., Nadauld, Lincoln, Barker, Tyler

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Precision medicine to improve survival without increasing costs in advanced cancer patients von Nadauld, Lincoln, Van Norman, S. Burke, Fulde, Gail, McDermott, Justin G., Newman, David, Butler, Allison M., Tudor, Brian P., Gilbert, Heather, Lin, Karen Yin, Stone, Gary, Ford, James M., Haslem, Derrick S.

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Precision oncology in advanced cancer patients improves overall survival with lower weekly healthcare costs von Haslem, Derrick S, Chakravarty, Ingo, Fulde, Gail, Gilbert, Heather, Tudor, Brian P, Lin, Karen, Ford, James M, Nadauld, Lincoln D

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Whole genome analysis identifies the association of TP53 genomic deletions with lower survival in Stage III colorectal cancer von Xia, Li C., Van Hummelen, Paul, Kubit, Matthew, Lee, HoJoon, Bell, John M., Grimes, Susan M., Wood-Bouwens, Christina, Greer, Stephanie U., Barker, Tyler, Haslem, Derrick S., Ford, James M., Fulde, Gail, Ji, Hanlee P., Nadauld, Lincoln D.

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Abstract PR07: Precision genomic medicine improves clinical outcomes in advanced cancer patients von Nadauld, Lincoln D., Norman, Burke Van, Fulde, Gail, newman, David, Butler, Allison, Tudor, Brian, Gilbert, Heather, Lin, Karen, Stone, Gary, Konde, Anish, Petrovchich, Iva, Ford, James M., Haslem, Derrick

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A Retrospective Analysis of Precision Medicine Outcomes in Patients With Advanced Cancer Reveals Improved Progression-Free Survival Without Increased Health Care Costs von Haslem, Derrick S, Van Norman, S Burke, Fulde, Gail, Knighton, Andrew J, Belnap, Tom, Butler, Allison M, Rhagunath, Sharanya, Newman, David, Gilbert, Heather, Tudor, Brian P, Lin, Karen, Stone, Gary R, Loughmiller, David L, Mishra, Pravin J, Srivastava, Rajendu, Ford, James M, Nadauld, Lincoln D

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Differences in the aromatic domain of homologous streptococcal fibronectin-binding proteins trigger different cell invasion mechanisms and survival rates von Rohde, Manfred, Graham, Rikki M, Branitzki-Heinemann, Katja, Borchers, Patricia, Preuss, Claudia, Schleicher, Ina, Zähner, Dorothea, Talay, Susanne R, Fulde, Marcus, Dinkla, Katrin, Chhatwal, Gursharan S

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