Mechanism of Action of Bortezomib and the New Proteasome Inhibitors on Myeloma Cells and the Bone Microenvironment: Impact on Myeloma-Induced Alterations of Bone Remodeling von Aversa, Franco, Dalla Palma, Benedetta, Bolzoni, Marina, Toscani, Denise, Accardi, Fabrizio, Giuliani, Nicola

Volltext

HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells von Carbone, Ennio, Neri, Paola, Mesuraca, Maria, Fulciniti, Mariateresa T., Otsuki, Takemi, Pende, Daniela, Groh, Veronika, Spies, Thomas, Pollio, Giuditta, Cosman, David, Catalano, Lucio, Tassone, Pierfrancesco, Rotoli, Bruno, Venuta, Salvatore

Volltext

ZNF423 and ZNF521: EBF1 Antagonists of Potential Relevance in B-Lymphoid Malignancies von Morrone, Giovanni, Nappo, Giovanna, Giordano, Marco, Codispoti, Bruna, Scicchitano, Stefania, Chiarella, Emanuela, Mesuraca, Maria, Bond, Heather M.

Volltext

Biallelic loss of BCMA as a resistance mechanism to CAR T cell therapy in a patient with multiple myeloma von Samur, Mehmet Kemal, Fulciniti, Mariateresa, Aktas Samur, Anil, Bazarbachi, Abdul Hamid, Tai, Yu-Tzu, Prabhala, Rao, Alonso, Alejandro, Sperling, Adam S., Campbell, Timothy, Petrocca, Fabio, Hege, Kristen, Kaiser, Shari, Loiseau, Hervé Avet, Anderson, Kenneth C., Munshi, Nikhil C.

Volltext

Mesenchymal stem cells: paving the way for myeloma onset? von Gulla, Annamaria, Fulciniti, Mariateresa

Volltext

Identification of novel mutational drivers reveals oncogene dependencies in multiple myeloma von Walker, Brian A., Mavrommatis, Konstantinos, Wardell, Christopher P., Ashby, T. Cody, Bauer, Michael, Davies, Faith E., Rosenthal, Adam, Wang, Hongwei, Qu, Pingping, Hoering, Antje, Samur, Mehmet, Towfic, Fadi, Ortiz, Maria, Flynt, Erin, Yu, Zhinuan, Yang, Zhihong, Rozelle, Dan, Obenauer, John, Trotter, Matthew, Auclair, Daniel, Keats, Jonathan, Bolli, Niccolo, Fulciniti, Mariateresa, Szalat, Raphael, Moreau, Philippe, Durie, Brian, Stewart, A. Keith, Goldschmidt, Hartmut, Raab, Marc S., Einsele, Hermann, Sonneveld, Pieter, San Miguel, Jesus, Lonial, Sagar, Jackson, Graham H., Anderson, Kenneth C., Avet-Loiseau, Herve, Munshi, Nikhil, Thakurta, Anjan, Morgan, Gareth J.

Volltext

A high-risk, Double-Hit, group of newly diagnosed myeloma identified by genomic analysis von Walker, Brian A., Mavrommatis, Konstantinos, Wardell, Christopher P., Ashby, T. Cody, Bauer, Michael, Davies, Faith, Rosenthal, Adam, Wang, Hongwei, Qu, Pingping, Hoering, Antje, Samur, Mehmet, Towfic, Fadi, Ortiz, Maria, Flynt, Erin, Yu, Zhinuan, Yang, Zhihong, Rozelle, Dan, Obenauer, John, Trotter, Matthew, Auclair, Daniel, Keats, Jonathan, Bolli, Niccolo, Fulciniti, Mariateresa, Szalat, Raphael, Moreau, Phillipe, Durie, Brian, Stewart, A. Keith, Goldschmidt, Hartmut, Raab, Marc S., Einsele, Hermann, Sonneveld, Pieter, San Miguel, Jesus, Lonial, Sagar, Jackson, Graham H., Anderson, Kenneth C., Avet-Loiseau, Herve, Munshi, Nikhil, Thakurta, Anjan, Morgan, Gareth

Volltext

Drugging the lncRNA MALAT1 via LNA gapmeR ASO inhibits gene expression of proteasome subunits and triggers anti-multiple myeloma activity von Amodio, Nicola, Stamato, Maria Angelica, Juli, Giada, Morelli, Eugenio, Fulciniti, Mariateresa, Manzoni, Martina, Taiana, Elisa, Agnelli, Luca, Cantafio, Maria Eugenia Gallo, Romeo, Enrica, Raimondi, Lavinia, Caracciolo, Daniele, Zuccalà, Valeria, Rossi, Marco, Neri, Antonino, Munshi, Nikhil C., Tagliaferri, Pierosandro, Tassone, Pierfrancesco

Volltext

Genomic landscape and chronological reconstruction of driver events in multiple myeloma von Maura, Francesco, Bolli, Niccoló, Angelopoulos, Nicos, Dawson, Kevin J., Leongamornlert, Daniel, Martincorena, Inigo, Mitchell, Thomas J., Fullam, Anthony, Gonzalez, Santiago, Szalat, Raphael, Abascal, Federico, Rodriguez-Martin, Bernardo, Samur, Mehmet Kemal, Glodzik, Dominik, Roncador, Marco, Fulciniti, Mariateresa, Tai, Yu Tzu, Minvielle, Stephane, Magrangeas, Florence, Moreau, Philippe, Corradini, Paolo, Anderson, Kenneth C., Tubio, Jose M. C., Wedge, David C., Gerstung, Moritz, Avet-Loiseau, Hervé, Munshi, Nikhil, Campbell, Peter J.

Volltext

Genomic patterns of progression in smoldering multiple myeloma von Bolli, Niccolò, Maura, Francesco, Minvielle, Stephane, Gloznik, Dominik, Szalat, Raphael, Fullam, Anthony, Martincorena, Inigo, Dawson, Kevin J., Samur, Mehmet Kemal, Zamora, Jorge, Tarpey, Patrick, Davies, Helen, Fulciniti, Mariateresa, Shammas, Masood A., Tai, Yu Tzu, Magrangeas, Florence, Moreau, Philippe, Corradini, Paolo, Anderson, Kenneth, Alexandrov, Ludmil, Wedge, David C., Avet-Loiseau, Herve, Campbell, Peter, Munshi, Nikhil

Volltext

Widespread intronic polyadenylation diversifies immune cell transcriptomes von Singh, Irtisha, Lee, Shih-Han, Sperling, Adam S., Samur, Mehmet K., Tai, Yu-Tzu, Fulciniti, Mariateresa, Munshi, Nikhil C., Mayr, Christine, Leslie, Christina S.

Volltext

Triplet Therapy, Transplantation, and Maintenance until Progression in Myeloma von Richardson, Paul G., Jacobus, Susanna J., Weller, Edie A., Hassoun, Hani, Lonial, Sagar, Raje, Noopur S., Medvedova, Eva, McCarthy, Philip L., Libby, Edward N., Voorhees, Peter M., Orlowski, Robert Z., Anderson, Larry D., Zonder, Jeffrey A., Milner, Carter P., Gasparetto, Cristina, Agha, Mounzer E., Khan, Abdullah M., Hurd, David D., Gowin, Krisstina, Kamble, Rammurti T., Jagannath, Sundar, Nathwani, Nitya, Alsina, Melissa, Cornell, R. Frank, Hashmi, Hamza, Campagnaro, Erica L., Andreescu, Astrid C., Gentile, Teresa, Liedtke, Michaela, Godby, Kelly N., Cohen, Adam D., Openshaw, Thomas H., Pasquini, Marcelo C., Giralt, Sergio A., Kaufman, Jonathan L., Yee, Andrew J., Scott, Emma, Torka, Pallawi, Foley, Amy, Fulciniti, Mariateresa, Hebert, Kyle, Samur, Mehmet K., Masone, Kelly, Maglio, Michelle E., Zeytoonjian, Andrea A., Nadeem, Omar, Schlossman, Robert L., Laubach, Jacob P., Paba-Prada, Claudia, Ghobrial, Irene M., Perrot, Aurore, Moreau, Philippe, Avet-Loiseau, Hervé, Attal, Michel, Anderson, Kenneth C., Munshi, Nikhil C.

Volltext

Protein arginine methyltransferase 5 has prognostic relevance and is a druggable target in multiple myeloma von Gullà, A, Hideshima, T, Bianchi, G, Fulciniti, M, Kemal Samur, M, Qi, J, Tai, Y-T, Harada, T, Morelli, E, Amodio, N, Carrasco, R, Tagliaferri, P, Munshi, N C, Tassone, P, Anderson, K C

Volltext

Unlocking the therapeutic potential of selective CDK7 and BRD4 Inhibition against multiple myeloma cell growth von Yao, Yao, Deng, Shuhui, Ng, Jessica Fong, Yuan, Mei, Chakraborty, Chandraditya, JoyWeiler, Vera, Munshi, Nikhil, Fulciniti, Mariateresa

Volltext

A novel role for CCL3 (MIP-1α) in myeloma-induced bone disease via osteocalcin downregulation and inhibition of osteoblast function von Vallet, S, Pozzi, S, Patel, K, Vaghela, N, Fulciniti, M T, Veiby, P, Hideshima, T, Santo, L, Cirstea, D, Scadden, D T, Anderson, K C, Raje, N

Volltext

Genome-Wide Somatic Alterations in Multiple Myeloma Reveal a Superior Outcome Group von Samur, Mehmet Kemal, Aktas Samur, Anil, Fulciniti, Mariateresa, Szalat, Raphael, Han, Tessa, Shammas, Masood, Richardson, Paul, Magrangeas, Florence, Minvielle, Stephane, Corre, Jill, Moreau, Philippe, Thakurta, Anjan, Anderson, Kenneth C., Parmigiani, Giovanni, Avet-Loiseau, Herve, Munshi, Nikhil C.

Volltext

Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells von Cea, Michele, Cagnetta, Antonia, Adamia, Sophia, Acharya, Chirag, Tai, Yu-Tzu, Fulciniti, Mariateresa, Ohguchi, Hiroto, Munshi, Aditya, Acharya, Prakrati, Bhasin, Manoj K., Zhong, Lei, Carrasco, Ruben, Monacelli, Fiammetta, Ballestrero, Alberto, Richardson, Paul, Gobbi, Marco, Lemoli, Roberto M., Munshi, Nikhil, Hideshima, Teru, Nencioni, Alessio, Chauhan, Dharminder, Anderson, Kenneth C.

Volltext

Bone marrow stromal cells induce chromatin remodeling in multiple myeloma cells leading to transcriptional changes von Binder, Moritz, Szalat, Raphael E., Talluri, Srikanth, Fulciniti, Mariateresa, Avet-Loiseau, Hervé, Parmigiani, Giovanni, Samur, Mehmet K., Munshi, Nikhil C.

Volltext

Elevated IL-17 produced by Th17 cells promotes myeloma cell growth and inhibits immune function in multiple myeloma von Prabhala, Rao H., Pelluru, Dheeraj, Fulciniti, Mariateresa, Prabhala, Harsha K., Nanjappa, Puru, Song, Weihua, Pai, Christine, Amin, Samir, Tai, Yu-Tzu, Richardson, Paul G., Ghobrial, Irene M., Treon, Steven P., Daley, John F., Anderson, Kenneth C., Kutok, Jeffery L., Munshi, Nikhil C.

Volltext

Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma von Fulciniti, Mariateresa, Tassone, Pierfrancesco, Hideshima, Teru, Vallet, Sonia, Nanjappa, Puru, Ettenberg, Seth A., Shen, Zhenxin, Patel, Nipun, Tai, Yu-tzu, Chauhan, Dharminder, Mitsiades, Constantine, Prabhala, Rao, Raje, Noopur, Anderson, Kenneth C., Stover, David R., Munshi, Nikhil C.

Volltext