CH5424802, a Selective ALK Inhibitor Capable of Blocking the Resistant Gatekeeper Mutant von Sakamoto, Hiroshi, Tsukaguchi, Toshiyuki, Hiroshima, Sayuri, Kodama, Tatsushi, Kobayashi, Takamitsu, Fukami, Takaaki A., Oikawa, Nobuhiro, Tsukuda, Takuo, Ishii, Nobuya, Aoki, Yuko

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Design and synthesis of novel macrocyclic 2-amino-6-arylpyrimidine Hsp90 inhibitors von Suda, Atsushi, Koyano, Hiroshi, Hayase, Tadakatsu, Hada, Kihito, Kawasaki, Ken-ichi, Komiyama, Susumu, Hasegawa, Kiyoshi, Fukami, Takaaki A., Sato, Shigeo, Miura, Takaaki, Ono, Naomi, Yamazaki, Toshikazu, Saitoh, Ryoichi, Shimma, Nobuo, Shiratori, Yasuhiko, Tsukuda, Takuo

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Synthesis and structure–activity relationships of novel benzofuran farnesyltransferase inhibitors von Asoh, Kohsuke, Kohchi, Masami, Hyoudoh, Ikumi, Ohtsuka, Tatsuo, Masubuchi, Miyako, Kawasaki, Kenichi, Ebiike, Hirosato, Shiratori, Yasuhiko, Fukami, Takaaki A., Kondoh, Osamu, Tsukaguchi, Toshiyuki, Ishii, Nobuya, Aoki, Yuko, Shimma, Nobuo, Sakaitani, Masahiro

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Crystal Structure of Uridine-diphospho-N-acetylglucosamine Pyrophosphorylase from Candida albicans and Catalytic Reaction Mechanism von Maruyama, Daisuke, Nishitani, Yuichi, Nonaka, Tsuyoshi, Kita, Akiko, Fukami, Takaaki A., Mio, Toshiyuki, Yamada-Okabe, Hisafumi, Yamada-Okabe, Toshiko, Miki, Kunio

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Design and synthesis of 2-amino-6-(1H,3H-benzo[de]isochromen-6-yl)-1,3,5-triazines as novel Hsp90 inhibitors von Suda, Atsushi, Kawasaki, Ken-ichi, Komiyama, Susumu, Isshiki, Yoshiaki, Yoon, Dong-Oh, Kim, Sung-Jin, Na, Young-Jun, Hasegawa, Kiyoshi, Fukami, Takaaki A., Sato, Shigeo, Miura, Takaaki, Ono, Naomi, Yamazaki, Toshikazu, Saitoh, Ryoichi, Shimma, Nobuo, Shiratori, Yasuhiko, Tsukuda, Takuo

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Discovery of 6-benzyloxyquinolines as c-Met selective kinase inhibitors von Nishii, Hiroki, Chiba, Takashi, Morikami, Kenji, Fukami, Takaaki A., Sakamoto, Hiroshi, Ko, Kwangseok, Koyano, Hiroshi

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Design and evaluation of azaindole-substituted N-hydroxypyridones as glyoxalase I inhibitors von Chiba, Takashi, Ohwada, Jun, Sakamoto, Hiroshi, Kobayashi, Takamitsu, Fukami, Takaaki A., Irie, Machiko, Miura, Takaaki, Ohara, Kazuhiro, Koyano, Hiroshi

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Lead generation of heat shock protein 90 inhibitors by a combination of fragment-based approach, virtual screening, and structure-based drug design von Miura, Takaaki, Fukami, Takaaki A., Hasegawa, Kiyoshi, Ono, Naomi, Suda, Atsushi, Shindo, Hidetoshi, Yoon, Dong-Oh, Kim, Sung-Jin, Na, Young-Jun, Aoki, Yuko, Shimma, Nobuo, Tsukuda, Takuo, Shiratori, Yasuhiko

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The Crystal Structure and Stereospecificity of Levodione Reductase from Corynebacterium aquaticum M-13 von Sogabe, Satoshi, Yoshizumi, Ayumi, Fukami, Takaaki A., Shiratori, Yasuhiko, Shimizu, Sakayu, Takagi, Hiroshi, Nakamori, Shigeru, Wada, Masaru

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Crystal Structures of N-Acetylglucosamine-phosphate Mutase, a Member of the α-d-Phosphohexomutase Superfamily, and Its Substrate and Product Complexes von Nishitani, Yuichi, Maruyama, Daisuke, Nonaka, Tsuyoshi, Kita, Akiko, Fukami, Takaaki A., Mio, Toshiyuki, Yamada-Okabe, Hisafumi, Yamada-Okabe, Toshiko, Miki, Kunio

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Properties of the Stochastic Energization-Relaxation Channel Model for Vectorial Ion Transport von Muneyuki, Eiro, Fukami, Takaaki A.

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Crystal Structure of Chaperonin-60 from Paracoccus denitrificans von Fukami, Takaaki A., Yohda, Masafumi, Taguchi, Hideki, Yoshida, Masasuke, Miki, Kunio

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Utilization of microgravity to improve the crystal quality of biologically important proteins: chaperonin-60, GrpE, B-subunit of V-type ATPase, and MIF von Kitano, Ken, Sasaki, Ryo, Nogi, Terukazu, Fukami, Takaaki A, Nakagawa, Atsushi, Miki, Kunio, Tanaka, Isao

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Purification, crystallization and preliminary X-ray diffraction studies of UDP-N-acetylglucosamine pyrophosphorylase from Candida albicans von Maruyama, Daisuke, Nishitani, Yuichi, Nonaka, Tsuyoshi, Kita, Akiko, Fukami, Takaaki A., Mio, Toshiyuki, Yamada-Okabe, Hisafumi, Yamada-Okabe, Toshiko, Miki, Kunio

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Abstract 3559: A new selective ALK inhibitor CH5424802 shows potent efficacy against ALK-positive cancers including the gatekeeper mutant-driven tumors von Sakamoto, Hiroshi, Tsukaguchi, Toshiyuki, Hiroshima, Sayuri, Kodama, Tatsushi, Kobayashi, Takamitsu, Fukami, Takaaki A., Oikawa, Nobuhiro, Tsukuda, Takuo, Ishii, Nobuya, Aoki, Yuko

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Crystal Structures of Candida albicans N-Myristoyltransferase with Two Distinct Inhibitors von Sogabe, Satoshi, Masubuchi, Miyako, Sakata, Kiyoaki, Fukami, Takaaki A., Morikami, Kenji, Shiratori, Yasuhiko, Ebiike, Hirosato, Kawasaki, Kenichi, Aoki, Yuko, Shimma, Nobuo, D'Arcy, Allan, Winkler, Fritz K., Banner, David W., Ohtsuka, Tatsuo

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Crystal Structures of N-Acetylglucosamine-phosphate Mutase, a Member of the α-d-Phosphohexomutase Superfamily, and Its Substrate and Product Complexes von Yuichi Nishitani, Daisuke Maruyama, Tsuyoshi Nonaka, Akiko Kita, Takaaki A. Fukami, Toshiyuki Mio, Hisafumi Yamada-Okabe, Toshiko Yamada-Okabe, Kunio Miki

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Purification, crystallization and preliminary X-ray diffraction studies of N-acetylglucosamine-phosphate mutase from Candida albicans von Nishitani, Yuichi, Maruyama, Daisuke, Nonaka, Tsuyoshi, Kita, Akiko, Fukami, Takaaki A., Mio, Toshiyuki, Yamada-Okabe, Hisafumi, Yamada-Okabe, Toshiko, Miki, Kunio

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Purification, Crystallization, and Preliminary X-ray Crystallographic Analysis of Thermus thermophilus V1-ATPase B Subunit von Nogi, Terukazu, Fukami, Takaaki A., Ishida, Masami, Yoshida, Masasuke, Miki, Kunio

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Crystallization and preliminary X-ray characterization of chaperonin-60 from Paracoccus denitrificans von Fukami, Takaaki A., Takasuga, Yoshio, Sumi, Masato, Yohda, Masafumi, Yoshida, Masasuke, Miki, Kunio

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