Advantage of the Dissolution/Permeation System for Estimating Oral Absorption of Drug Candidates in the Drug Discovery Stage von Miyaji, Yoshihiro, Fujii, Yoshimine, Takeyama, Shoko, Kawai, Yukinori, Kataoka, Makoto, Takahashi, Masayuki, Yamashita, Shinji

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Profiling and Trend Analysis of Food Effects on Oral Drug Absorption Considering Micelle Interaction and Solubilization by Bile Micelles von Kawai, Yukinori, Fujii, Yoshimine, Tabata, Fumiko, Ito, Junko, Metsugi, Yukiko, Kameda, Atsuko, Akimoto, Katsuya, Takahashi, Masayuki

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Improvement of low bioavailability of a novel factor Xa inhibitor through formulation of cationic additives in its oral dosage form von Fujii, Yoshimine, Kanamaru, Taro, Kikuchi, Hiroshi, Nakagami, Hiroaki, Yamashita, Shinji, Akashi, Mitsuru, Sakuma, Shinji

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Evaluation of Serum Protein Binding by Using in Vitro Pharmacological Activity for the Effective Pharmacokinetics Profiling in Drug Discovery von Kawai, Yukinori, Fujii, Yoshimine, Akimoto, Katsuya, Takahashi, Masayuki

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Enteric-coated tablets improve oral bioavailability of DX-9065, a novel anticoagulant von Fujii, Yoshimine, Kanamaru, Taro, Kikuchi, Hiroshi, Yamashita, Shinji, Sakuma, Shinji

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Approaches to improving the oral bioavailabity of the low-permeability compound DX-9065, and species differences in bioavailability in preclinical and clinical studies von Fujii, Yoshimine

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Characterization of Gastrointestinal Drug Absorption in Cynomolgus Monkeys von Takahashi, Masayuki, Washio, Takuo, Suzuki, Norio, Igeta, Katsuhiro, Fujii, Yoshimine, Hayashi, Masahiro, Shirasaka, Yoshiyuki, Yamashita, Shinji

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Characteristics of Gastrointestinal Absorption of DX-9065a, a New Synthetic Anticoagulant von Fujii, Yoshimine, Takahashi, Masayuki, Morita, Hiromi, Kikuchi, Hiroshi, Aramaki, Yukihiko, Amidon, Gordon L.

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In Vitro Assessment of Supersaturation/Precipitation and Biological Membrane Permeation of Poorly Water-Soluble Drugs: A Case Study With Albendazole and Ketoconazole von Kataoka, Makoto, Takeyama, Shoko, Minami, Keiko, Higashino, Haruki, Kakimi, Kohichi, Fujii, Yoshimine, Takahashi, Masayuki, Yamashita, Shinji

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低膜透過性化合物DX-9065の経口吸収改善と種差 von 藤井, 義峰

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New biphasic system in side-by-side chambers for testing drug dissolution and permeation in vitro (BiDP system) von Masada, Takato, Takagi, Toshihide, Minami, Keiko, Kataoka, Makoto, Takeyama, Shoko, Fujii, Yoshimine, Takahashi, Masayuki, Yamashita, Shinji

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Interspecies differences in gastrointestinal physiology affecting the in vivo performance of oral pharmaceutical solid dosage forms von Kambayashi, Atsushi, Murano, Mika, Imai, Shunji, Miyata, Kenichi, Sugita, Katsuji, Fujii, Yoshimine, Kinoshita, Masahiro, Nomura, Akinori, Kimoto, Takahiro, Miyazaki, Yoshikazu, Sakakibara, Hiroyuki, Kakuda, Sahoe, Tsujimoto, Takuya, Fujita, Yuu, Kano, Mayumi, Nakamura, Hideaki, Akaogi, Seiichirou, Honda, Makoto, Anraku, Makoto, Kamada, Noboru, Ohta, Kotoe, Uchida, Masashi, Kataoka, Makoto, Kikuchi, Hiroshi, Yamashita, Shinji, Kondo, Hiromu

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Cyclodextrins improve oral absorption of a novel factor Xa inhibitor by interfering with interaction between the drug and bile acids in rats von Fujii, Yoshimine, Takahashi, Masayuki, Ishiguro, Takako, Sakuma, Shinji, Uekama, Kaneto, Irie, Tetsumi

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Gastrointestinal System von Fujii, Yoshimine, Sakuma, Shinji

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Uptake of phosphatidylserine liposomes by rat Peyer's patches following intraluminal administration von TOMIZAWA, H, ARAMAKI, Y, FUJII, Y, HARA, T, SUZUKI, N, YACHI, K, KIKUCHI, H, TSUCHIYA, S

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Activation of systemic and mucosal immune response following nasal administration of liposomes von Aramaki, Yukihiko, Fujii, Yoshimine, Yachi, Kiyoto, Kikuchi, Hiroshi, Tsuchiya, Seishi

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ANTIBACTERIAL WATER-BASED PREPARATION von FUJII YOSHIMINE, TOMIZUKA TOSHIAKI

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Enhancement of systemic and mucosal immune responses following oral administration of liposomes von Fujii, Yoshimine, Aramaki, Yukihiko, Hara, Toshifumi, Yachi, Kiyoto, Kikuchi, Hiroshi, Tsuchiya, Seishi

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LYOPHILIZATION PRODUCT von FUJII, YOSHIMINE, SUZUKI, NORIO

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ANTIBACTERIAL WATER-BASED PREPARATION von TOSHIAKI TOMITSUKA, YOSHIMINE FUJII

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