DPPC-cholesterol phase diagram using coarse-grained Molecular Dynamics simulations von Wang, Yin, Gkeka, Paraskevi, Fuchs, Julian E., Liedl, Klaus R., Cournia, Zoe

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A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo von Kofink, Christiane, Trainor, Nicole, Mair, Barbara, Wöhrle, Simon, Wurm, Melanie, Mischerikow, Nikolai, Roy, Michael J., Bader, Gerd, Greb, Peter, Garavel, Géraldine, Diers, Emelyne, McLennan, Ross, Whitworth, Claire, Vetma, Vesna, Rumpel, Klaus, Scharnweber, Maximilian, Fuchs, Julian E., Gerstberger, Thomas, Cui, Yunhai, Gremel, Gabriela, Chetta, Paolo, Hopf, Stefan, Budano, Nicole, Rinnenthal, Joerg, Gmaschitz, Gerhard, Mayer, Moriz, Koegl, Manfred, Ciulli, Alessio, Weinstabl, Harald, Farnaby, William

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The impact of nitration on the structure and immunogenicity of the major birch pollen allergen Bet v 1.0101 von Ackaert, Chloé, Kofler, Stefan, Horejs-Hoeck, Jutta, Zulehner, Nora, Asam, Claudia, von Grafenstein, Susanne, Fuchs, Julian E, Briza, Peter, Liedl, Klaus R, Bohle, Barbara, Ferreira, Fátima, Brandstetter, Hans, Oostingh, Gertie J, Duschl, Albert

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PI by NMR: Probing CH–π Interactions in Protein–Ligand Complexes by NMR Spectroscopy von Platzer, Gerald, Mayer, Moriz, Beier, Andreas, Brüschweiler, Sven, Fuchs, Julian E., Engelhardt, Harald, Geist, Leonhard, Bader, Gerd, Schörghuber, Julia, Lichtenecker, Roman, Wolkerstorfer, Bernhard, Kessler, Dirk, McConnell, Darryl B., Konrat, Robert

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Peptidic Macrocycles - Conformational Sampling and Thermodynamic Characterization von Kamenik, Anna S, Lessel, Uta, Fuchs, Julian E, Fox, Thomas, Liedl, Klaus R

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Cooperative Binding of Aflatoxin B1 by Cytochrome P450 3A4: A Computational Study von Bren, Urban, Fuchs, Julian E, Oostenbrink, Chris

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Asymmetric arginine dimethylation of RelA provides a repressive mark to modulate TNFα/NF-κB response von Reintjes, Anja, Fuchs, Julian E., Kremser, Leopold, Lindner, Herbert H., Liedl, Klaus R., Huber, Lukas A., Valovka, Taras

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Start Selective and Rigidify: The Discovery Path toward a Next Generation of EGFR Tyrosine Kinase Inhibitors von Engelhardt, Harald, Böse, Dietrich, Petronczki, Mark, Scharn, Dirk, Bader, Gerd, Baum, Anke, Bergner, Andreas, Chong, Eugene, Döbel, Sandra, Egger, Georg, Engelhardt, Christian, Ettmayer, Peter, Fuchs, Julian E, Gerstberger, Thomas, Gonnella, Nina, Grimm, Andreas, Grondal, Elisabeth, Haddad, Nizar, Hopfgartner, Barbara, Kousek, Roland, Krawiec, Mariusz, Kriz, Monika, Lamarre, Lyne, Leung, Joyce, Mayer, Moriz, Patel, Nitinchandra D, Simov, Biljana Peric, Reeves, Jonathan T, Schnitzer, Renate, Schrenk, Andreas, Sharps, Bernadette, Solca, Flavio, Stadtmüller, Heinz, Tan, Zhulin, Wunberg, Tobias, Zoephel, Andreas, McConnell, Darryl B

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Heteroaromatic π‑Stacking Energy Landscapes von Huber, Roland G, Margreiter, Michael A, Fuchs, Julian E, von Grafenstein, Susanne, Tautermann, Christofer S, Liedl, Klaus R, Fox, Thomas

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Development of a Novel Azaspirane That Targets the Janus Kinase-Signal Transducer and Activator of Transcription (STAT) Pathway in Hepatocellular Carcinoma in Vitro and in Vivo von Mohan, Chakrabhavi Dhananjaya, Bharathkumar, Hanumantharayappa, Bulusu, Krishna C., Pandey, Vijay, Rangappa, Shobith, Fuchs, Julian E., Shanmugam, Muthu K., Dai, Xiaoyun, Li, Feng, Deivasigamani, Amudha, Hui, Kam M., Kumar, Alan Prem, Lobie, Peter E., Bender, Andreas, Basappa, Salundi, Sethi, Gautam, Rangappa, Kanchugarakoppal S.

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Probing Protein–Ligand Methyl−π Interaction Geometries through Chemical Shift Measurements of Selectively Labeled Methyl Groups von Beier, Andreas, Platzer, Gerald, Höfurthner, Theresa, Ptaszek, Aleksandra L., Lichtenecker, Roman J., Geist, Leonhard, Fuchs, Julian E., McConnell, Darryl B., Mayer, Moriz, Konrat, Robert

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Matched Molecular Pair Analysis: Significance and the Impact of Experimental Uncertainty von Kramer, Christian, Fuchs, Julian E, Whitebread, Steven, Gedeck, Peter, Liedl, Klaus R

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Strong Nonadditivity as a Key Structure–Activity Relationship Feature: Distinguishing Structural Changes from Assay Artifacts von Kramer, Christian, Fuchs, Julian E, Liedl, Klaus R

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Characterizing Protease Specificity: How Many Substrates Do We Need? von Schauperl, Michael, Fuchs, Julian E, Waldner, Birgit J, Huber, Roland G, Kramer, Christian, Liedl, Klaus R

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Fold stability during endolysosomal acidification is a key factor for allergenicity and immunogenicity of the major birch pollen allergen von Machado, Yoan, MSc, Freier, Regina, MSc, Scheiblhofer, Sandra, PhD, Thalhamer, Theresa, PhD, Mayr, Melissa, BSc, Briza, Peter, PhD, Grutsch, Sarina, PhD, Ahammer, Linda, MSc, Fuchs, Julian E., PhD, Wallnoefer, Hannes G., PhD, Isakovic, Almedina, MSc, Kohlbauer, Vera, MSc, Hinterholzer, Arthur, BSc, Steiner, Markus, MSc, Danzer, Martin, MSc, Horejs-Hoeck, Jutta, PhD, Ferreira, Fatima, PhD, Liedl, Klaus R., PhD, Tollinger, Martin, PhD, Lackner, Peter, PhD, Johnson, Christopher M., PhD, Brandstetter, Hans, PhD, Thalhamer, Josef, PhD, Weiss, Richard, PhD

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Dynamics Govern Specificity of a Protein-Protein Interface: Substrate Recognition by Thrombin von Fuchs, Julian E, Huber, Roland G, Waldner, Birgit J, Kahler, Ursula, von Grafenstein, Susanne, Kramer, Christian, Liedl, Klaus R

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Rationalizing Tight Ligand Binding through Cooperative Interaction Networks von Kuhn, Bernd, Fuchs, Julian E, Reutlinger, Michael, Stahl, Martin, Taylor, Neil R

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Discovery of a small-molecule inhibitor of specific serine residue BAD phosphorylation von Pandey, Vijay, Wang, Baocheng, Mohan, Chakrabhavi Dhananjaya, Raquib, Ainiah Rushdiana, Rangappa, Shobith, Srinivasa, Venkatachalaiah, Fuchs, Julian E., Girish, Kesturu S., Zhu, Tao, Bender, Andreas, Ma, Lan, Yin, Zhinan, Basappa, Rangappa, Kanchugarakoppal S., Lobie, Peter E.

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Ligand Binding Modulates the Structural Dynamics and Compactness of the Major Birch Pollen Allergen von Grutsch, Sarina, Fuchs, Julian E., Freier, Regina, Kofler, Stefan, Bibi, Marium, Asam, Claudia, Wallner, Michael, Ferreira, Fátima, Brandstetter, Hans, Liedl, Klaus R., Tollinger, Martin

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A One Pot Synthesis of Novel Bioactive Tri-Substitute-Condensed-Imidazopyridines that Targets Snake Venom Phospholipase A2 von Anilkumar, Nirvanappa C, Sundaram, Mahalingam S, Mohan, Chakrabhavi Dhananjaya, Rangappa, Shobith, Bulusu, Krishna C, Fuchs, Julian E, Girish, Kesturu S, Bender, Andreas, Basappa, Rangappa, Kanchugarakoppal S

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