Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection von Bradley, Konrad C., Finsterbusch, Katja, Schnepf, Daniel, Crotta, Stefania, Llorian, Miriam, Davidson, Sophia, Fuchs, Serge Y., Staeheli, Peter, Wack, Andreas

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Hope and fear for interferon: the receptor-centric outlook on the future of interferon therapy von Fuchs, Serge Y

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DNA-Damage-Induced Type I Interferon Promotes Senescence and Inhibits Stem Cell Function von Yu, Qiujing, Katlinskaya, Yuliya V., Carbone, Christopher J., Zhao, Bin, Katlinski, Kanstantsin V., Zheng, Hui, Guha, Manti, Li, Ning, Chen, Qijun, Yang, Ting, Lengner, Christopher J., Greenberg, Roger A., Johnson, F. Brad, Fuchs, Serge Y.

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miR-211 Is a Prosurvival MicroRNA that Regulates chop Expression in a PERK-Dependent Manner von Chitnis, Nilesh S., Pytel, Dariusz, Bobrovnikova-Marjon, Ekaterina, Pant, Dhruv, Zheng, Hui, Maas, Nancy L., Frederick, Brian, Kushner, Jake A., Chodosh, Lewis A., Koumenis, Constantinos, Fuchs, Serge Y., Diehl, J. Alan

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miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis von Xu, Zhenhua, Bu, Yiwen, Chitnis, Nilesh, Koumenis, Costas, Fuchs, Serge Y., Diehl, J. Alan

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Hemagglutinin of Influenza A Virus Antagonizes Type I Interferon (IFN) Responses by Inducing Degradation of Type I IFN Receptor 1 von Xia, Chuan, Vijayan, Madhuvanthi, Pritzl, Curtis J, Fuchs, Serge Y, McDermott, Adrian B, Hahm, Bumsuk

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Immune suppressive activity of myeloid-derived suppressor cells in cancer requires inactivation of the type I interferon pathway von Alicea-Torres, Kevin, Sanseviero, Emilio, Gui, Jun, Chen, Jinyun, Veglia, Filippo, Yu, Qiujin, Donthireddy, Laxminarasimha, Kossenkov, Andrew, Lin, Cindy, Fu, Shuyu, Mulligan, Charles, Nam, Brian, Masters, Gregory, Denstman, Fred, Bennett, Joseph, Hockstein, Neil, Rynda-Apple, Agnieszka, Nefedova, Yulia, Fuchs, Serge Y., Gabrilovich, Dmitry I.

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Tumor factors stimulate lysosomal degradation of tumor antigens and undermine their cross-presentation in lung cancer von Lu, Zhen, Chen, Jinyun, Yu, Pengfei, Atherton, Matthew J., Gui, Jun, Tomar, Vivek S., Middleton, Justin D., Sullivan, Neil T., Singhal, Sunil, George, Subin S., Woolfork, Ashley G., Weljie, Aalim M., Hai, Tsonwin, Eruslanov, Evgeniy B., Fuchs, Serge Y.

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A BRISC-SHMT Complex Deubiquitinates IFNAR1 and Regulates Interferon Responses von Zheng, Hui, Gupta, Vibhor, Patterson-Fortin, Jeffrey, Bhattacharya, Sabyasachi, Katlinski, Kanstantsin, Wu, Junmin, Varghese, Bentley, Carbone, Christopher J., Aressy, Bernadette, Fuchs, Serge Y., Greenberg, Roger A.

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Type I interferons mediate pancreatic toxicities of PERK inhibition von Yu, Qiujing, Zhao, Bin, Gui, Jun, Katlinski, Kanstantsin V., Brice, Angela, Gao, Yan, Li, ChangHong, Kushner, Jake A., Koumenis, Constantinos, Diehl, J. Alan, Fuchs, Serge Y.

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PERK Is a Haploinsufficient Tumor Suppressor: Gene Dose Determines Tumor-Suppressive Versus Tumor Promoting Properties of PERK in Melanoma von Pytel, Dariusz, Gao, Yan, Mackiewicz, Katarzyna, Katlinskaya, Yuliya V, Staschke, Kirk A, Paredes, Maria C G, Yoshida, Akihiro, Qie, Shuo, Zhang, Gao, Chajewski, Olga S, Wu, Lawrence, Majsterek, Ireneusz, Herlyn, Meenhard, Fuchs, Serge Y, Diehl, J Alan

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Type I Interferon Controls Propagation of Long Interspersed Element-1 von Yu, Qiujing, Carbone, Christopher J., Katlinskaya, Yuliya V., Zheng, Hui, Zheng, Ke, Luo, Mengcheng, Wang, P. Jeremy, Greenberg, Roger A., Fuchs, Serge Y.

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Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression von Katlinskaya, Yuliya V., Katlinski, Kanstantsin V., Yu, Qiujing, Ortiz, Angelica, Beiting, Daniel P., Brice, Angela, Davar, Diwakar, Sanders, Cindy, Kirkwood, John M., Rui, Hallgeir, Xu, Xiaowei, Koumenis, Constantinos, Diehl, J. Alan, Fuchs, Serge Y.

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Tumor suppressor mediated ubiquitylation of hnRNPK is a barrier to oncogenic translation von Mucha, Bartosz, Qie, Shuo, Bajpai, Sagar, Tarallo, Vincenzo, Diehl, J. Nathaniel, Tedeschi, Frank, Zhou, Gao, Gao, Zhaofeng, Flashner, Samuel, Klein-Szanto, Andres J., Hibshoosh, Hanina, Masataka, Shimonosono, Chajewski, Olga S., Majsterek, Ireneusz, Pytel, Dariusz, Hatzoglou, Maria, Der, Channing J., Nakagawa, Hiroshi, Bass, Adam J., Wong, Kwok-Kin, Fuchs, Serge Y., Rustgi, Anil K., Jankowsky, Eckhard, Diehl, J. Alan

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Anti-tumorigenic effects of Type 1 interferon are subdued by integrated stress responses von Bhattacharya, S, HuangFu, W-C, Dong, G, Qian, J, Baker, D P, Karar, J, Koumenis, C, Diehl, J A, Fuchs, S Y

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UBP43 is a novel regulator of interferon signaling independent of its ISG15 isopeptidase activity von Malakhova, Oxana A, Kim II, Keun, Luo, Jiann-Kae, Zou, Weiguo, Kumar, KG Suresh, Fuchs, Serge Y, Shuai, Ke, Zhang, Dong-Er

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Pathogen recognition receptor signaling accelerates phosphorylation-dependent degradation of IFNAR1 von Qian, Juan, Zheng, Hui, Huangfu, Wei-Chun, Liu, Jianghuai, Carbone, Christopher J, Leu, N Adrian, Baker, Darren P, Fuchs, Serge Y

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MEKK1/JNK Signaling Stabilizes and Activates p53 von Fuchs, Serge Y., Adler, Victor, Pincus, Matthew R., Ze'ev Ronai

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Inflammatory signaling compromises cell responses to interferon alpha von HuangFu, W-C, Qian, J, Liu, C, Liu, J, Lokshin, A E, Baker, D P, Rui, H, Fuchs, S Y

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Tyrosine Phosphorylation of Protein Kinase D2 Mediates Ligand-inducible Elimination of the Type 1 Interferon Receptor von Zheng, Hui, Qian, Juan, Baker, Darren P., Fuchs, Serge Y.

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