Homeostatic Restoration of Desmoplastic Stroma Rather Than Its Ablation Slows Pancreatic Cancer Progression von Froeling, Fieke E.M, Kocher, Hemant M

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Retinoic Acid–Induced Pancreatic Stellate Cell Quiescence Reduces Paracrine Wnt–β-Catenin Signaling to Slow Tumor Progression von Froeling, Fieke E.M, Feig, Christine, Chelala, Claude, Dobson, Richard, Mein, Charles E, Tuveson, David A, Clevers, Hans, Hart, Ian R, Kocher, Hemant M

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Organotypic Culture Model of Pancreatic Cancer Demonstrates that Stromal Cells Modulate E-Cadherin, β-Catenin, and Ezrin Expression in Tumor Cells von Froeling, Fieke E.M, Mirza, Tariq A, Feakins, Roger M, Seedhar, Angela, Elia, George, Hart, Ian R, Kocher, Hemant M

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Pancreatic cancer organotypic cultures von Froeling, Fieke E.M., Marshall, John F., Kocher, Hemant M.

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Phase I clinical trial repurposing all-trans retinoic acid as a stromal targeting agent for pancreatic cancer von Kocher, Hemant M., Basu, Bristi, Froeling, Fieke E. M., Sarker, Debashis, Slater, Sarah, Carlin, Dominic, deSouza, Nandita M., De Paepe, Katja N., Goulart, Michelle R., Hughes, Christine, Imrali, Ahmet, Roberts, Rhiannon, Pawula, Maria, Houghton, Richard, Lawrence, Cheryl, Yogeswaran, Yathushan, Mousa, Kelly, Coetzee, Carike, Sasieni, Peter, Prendergast, Aaron, Propper, David J.

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Homologous Recombination Deficiency in Pancreatic Cancer: A Systematic Review and Prevalence Meta-Analysis von Casolino, Raffaella, Paiella, Salvatore, Azzolina, Danila, Beer, Philip A, Corbo, Vincenzo, Lorenzoni, Giulia, Gregori, Dario, Golan, Talia, Braconi, Chiara, Froeling, Fieke E M, Milella, Michele, Scarpa, Aldo, Pea, Antonio, Malleo, Giuseppe, Salvia, Roberto, Bassi, Claudio, Chang, David K, Biankin, Andrew V

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Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution von Chan-Seng-Yue, Michelle, Kim, Jaeseung C., Wilson, Gavin W., Ng, Karen, Figueroa, Eugenia Flores, O’Kane, Grainne M., Connor, Ashton A., Denroche, Robert E., Grant, Robert C., McLeod, Jessica, Wilson, Julie M., Jang, Gun Ho, Zhang, Amy, Dodd, Anna, Liang, Sheng-Ben, Borgida, Ayelet, Chadwick, Dianne, Kalimuthu, Sangeetha, Lungu, Ilinca, Bartlett, John M. S., Krzyzanowski, Paul M., Sandhu, Vandana, Tiriac, Hervé, Froeling, Fieke E. M., Karasinska, Joanna M., Topham, James T., Renouf, Daniel J., Schaeffer, David F., Jones, Steven J. M., Marra, Marco A., Laskin, Janessa, Chetty, Runjan, Stein, Lincoln D., Zogopoulos, George, Haibe-Kains, Benjamin, Campbell, Peter J., Tuveson, David A., Knox, Jennifer J., Fischer, Sandra E., Gallinger, Steven, Notta, Faiyaz

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Intensified therapies improve survival and identification of novel prognostic factors for placental-site and epithelioid trophoblastic tumours von Froeling, Fieke E. M., Ramaswami, Ramya, Papanastasopoulos, Panagiotis, Kaur, Baljeet, Sebire, Neil J., Short, Dee, Fisher, Rosemary A., Sarwar, Naveed, Wells, Michael, Singh, Kam, Ellis, Laura, Horsman, Janet M., Winter, Matthew C., Tidy, John, Hancock, Barry W., Seckl, Michael J.

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Bioactivation of Napabucasin Triggers Reactive Oxygen Species-Mediated Cancer Cell Death von Froeling, Fieke E M, Swamynathan, Manojit Mosur, Deschênes, Astrid, Chio, Iok In Christine, Brosnan, Erin, Yao, Melissa A, Alagesan, Priya, Lucito, Matthew, Li, Juying, Chang, An-Yun, Trotman, Lloyd C, Belleau, Pascal, Park, Youngkyu, Rogoff, Harry A, Watson, James D, Tuveson, David A

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Internally Controlled and Dynamic Optical Measures of Functional Tumor Biology von Chung, Taemoon, Garcia, Libia, Swamynathan, Manojit M., Froeling, Fieke E. M., Trotman, Lloyd C., Tuveson, David A., Lyons, Scott K.

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Exploring the Biology of Cancer-Associated Fibroblasts in Pancreatic Cancer von Bryce, Adam S, Dreyer, Stephan B, Froeling, Fieke E. M, Chang, David K

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Imbalance of desmoplastic stromal cell numbers drives aggressive cancer processes von Kadaba, Raghu, Birke, Hanna, Wang, Jun, Hooper, Steven, Andl, Claudia D, Di Maggio, Francesco, Soylu, Erdinc, Ghallab, Mohammed, Bor, Daniel, Froeling, Fieke EM, Bhattacharya, Satyajit, Rustgi, Anil K, Sahai, Erik, Chelala, Claude, Sasieni, Peter, Kocher, Hemant M

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Molecular Subtyping and Precision Medicine for Pancreatic Cancer von Froeling, Fieke E M, Casolino, Raffaella, Pea, Antonio, Biankin, Andrew V, Chang, David K

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Gestational Trophoblastic Tumours: An Update for 2014 von Froeling, Fieke E. M., Seckl, Michael J.

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Precision medicine and a molecular tumour board for pancreatic cancer in the UK national health service von Froeling, Fieke E.M., Bradley, Sarah, Dixon, Judith, Upstill-Goddard, Rosie, Grimwood, Paul, Westwood, Paul, Biankin, Andrew V., Beer, Philip A., Graham, Janet, Valle, Juan, Chang, David K.

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Uncaria tomentosa , the cat's whiskers or claws? von Froeling, Fieke E M, Stebbing, Justin

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RhoC interacts with integrin α5β1 and enhances its trafficking in migrating pancreatic carcinoma cells von Li, Ningfeng Fiona, Gemenetzidis, Emilios, Marshall, Francis J, Davies, Derek, Yu, Yongwei, Frese, Kristopher, Froeling, Fieke E M, Woolf, Adam K, Feakins, Roger M, Naito, Yoshiki, Iacobuzio-Donahue, Christine, Tuveson, David A, Hart, Ian R, Kocher, Hemant M

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Organoid Personalized Therapeutics and the Pancreatic Adenocarcinoma Signature Stratification for treatment (PASS) – 01 trial von Froeling, Fieke E.M., Plenker, Dennis, O’Kane, Grainne, Aguirre, Andrew J., Wolpin, Brian M., Laheru, Daniel A., Saif, M Wasif, Yu, Kenneth H., Fischer, Sandra, Gallinger, Steven, Knox, Jennifer J., Jaffee, Elizabeth M., Tuveson, David A.

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Abstract PR04: Therapeutic development platform for pancreatic cancer in the UK national health service: Lessons learned and initial results from Precision-Panc von Froeling, Fieke E.M., Valle, Juan, Upstill-Goddard, Rosie, Grimwood, Paul, Westwood, Paul, Dreyer, Stephan B., Kelly, Caroline, Duthie, Fraser, Dixon, Judith, Bradley, Sarah, Evans, T.R. Jeffry, Sansom, Owen J., Biankin, Andrew V., Chang, David K.

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Ezrin Expression Is an Independent Prognostic Factor in Gastro-intestinal Cancers von Arumugam, Prabhu, Partelli, Stefano, Coleman, Stacey J., Cataldo, Ivana, Beghelli, Stefania, Bassi, Claudio, Wijesuriya, Nilukushi, Aleong, Jo-Anne Chin, Froeling, Fieke E. M., Scarpa, Aldo, Kocher, Hemant M.

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