Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression von Roy, Bijoyita, Friesen, Westley J., Tomizawa, Yuki, Leszyk, John D., Zhuo, Jin, Johnson, Briana, Dakka, Jumana, Trotta, Christopher R., Xue, Xiaojiao, Mutyam, Venkateshwar, Keeling, Kim M., Mobley, James A., Rowe, Steven M., Bedwell, David M., Welch, Ellen M., Jacobson, Allan

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The minor gentamicin complex component, X2, is a potent premature stop codon readthrough molecule with therapeutic potential von Friesen, Westley J, Johnson, Briana, Sierra, Jairo, Zhuo, Jin, Vazirani, Priya, Xue, Xiaojiao, Tomizawa, Yuki, Baiazitov, Ramil, Morrill, Christie, Ren, Hongyu, Babu, Suresh, Moon, Young-Choon, Branstrom, Art, Mollin, Anna, Hedrick, Jean, Sheedy, Josephine, Elfring, Gary, Weetall, Marla, Colacino, Joseph M, Welch, Ellen M, Peltz, Stuart W

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SMN, the Product of the Spinal Muscular Atrophy Gene, Binds Preferentially to Dimethylarginine-Containing Protein Targets von Friesen, Westley J, Massenet, Severine, Paushkin, Sergey, Wyce, Anastasia, Dreyfuss, Gideon

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Guanidino quinazolines and pyrimidines promote readthrough of premature termination codons in cells with native nonsense mutations von Morrill, Christie, Friesen, Westley J., Babu, Suresh, Baiazitov, Ramil Y., Du, Wu, Karloff, Diane B., Lee, Chang-Sun, Moon, Young-Choon, Ren, Hongyu, Sierra, Jairo, Tomizawa, Yuki, Vazirani, Priya, Welch, Ellen M., Xue, Xiaojiao, Zhuo, Jin

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PTC124 targets genetic disorders caused by nonsense mutations von Chen, Guangming, Jacobson, Allan, Spatrick, Phyllis, Peltz, Stuart W, Conn, M. Morgan, Friesen, Westley J, Almstead, Neil G, Hedrick, Jean, Campbell, Jeffrey A, Mollin, Anna, Kawana, Masataka, Wilde, Richard G, Yeh, Shirley, Sweeney, H. Lee, Trotta, Christopher R, Khan, Atiyya, Welch, Ellen M, Barton, Elisabeth R, Hirawat, Samit, Turpoff, Anthony A, Weetall, Marla, Ren, Hongyu, Risher, Nicole, Tomizawa, Yuki, Northcutt, Valerie J, Miller, Langdon L, He, Feng, Jones, Stephen, Colacino, Joseph M, Feng, Huisheng, Branstrom, Arthur A, Corson, Donald, Zhuo, Jin, Ju, William D, Patel, Meenal, Moon, Young-Choon, Hwang, Seongwoo, Paushkin, Sergey, Babiak, John, Trifillis, Panayiota, Karp, Gary, Takasugi, James

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The nucleoside analog clitocine is a potent and efficacious readthrough agent von Friesen, Westley J, Trotta, Christopher R, Tomizawa, Yuki, Zhuo, Jin, Johnson, Briana, Sierra, Jairo, Roy, Bijoyita, Weetall, Marla, Hedrick, Jean, Sheedy, Josephine, Takasugi, James, Moon, Young-Choon, Babu, Suresh, Baiazitov, Ramil, Leszyk, John D, Davis, Thomas W, Colacino, Joseph M, Peltz, Stuart W, Welch, Ellen M

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Detection of Arginine Dimethylated Peptides by Parallel Precursor Ion Scanning Mass Spectrometry in Positive Ion Mode von Rappsilber, Juri, Friesen, Westley J, Paushkin, Sergey, Dreyfuss, Gideon, Mann, Matthias

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A Novel WD Repeat Protein Component of the Methylosome Binds Sm Proteins von Friesen, Westley J., Wyce, Anastasia, Paushkin, Sergey, Abel, Linda, Rappsilber, Juri, Mann, Matthias, Dreyfuss, Gideon

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The Methylosome, a 20S Complex Containing JBP1 and pICln, Produces Dimethylarginine-Modified Sm Proteins von Friesen, Westley J., Paushkin, Sergey, Wyce, Anastasia, Massenet, Severine, Pesiridis, G. Scott, Van Duyne, Gregory, Rappsilber, Juri, Mann, Matthias, Dreyfuss, Gideon

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Specific Sequences of the Sm and Sm-like (Lsm) Proteins Mediate Their Interaction with the Spinal Muscular Atrophy Disease Gene Product (SMN) von Friesen, W J, Dreyfuss, G

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Chemical modifications of G418 (geneticin): Synthesis of novel readthrough aminoglycosides results in an improved in vitro safety window but no improvements in vivo von Baiazitov, Ramil Y., Friesen, Westley, Johnson, Briana, Mollin, Anna, Sheedy, Josephine, Sierra, Jairo, Weetall, Marla, Branstrom, Arthur, Welch, Ellen, Moon, Young-Choon

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New in Vitro Assay Measuring Direct Interaction of Nonsense Suppressors with the Eukaryotic Protein Synthesis Machinery von Ng, Martin Y, Zhang, Haibo, Weil, Amy, Singh, Vijay, Jamiolkowski, Ryan, Baradaran-Heravi, Alireza, Roberge, Michel, Jacobson, Allan, Friesen, Westley, Welch, Ellen, Goldman, Yale E, Cooperman, Barry S

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Phage Display of RNA Binding Zinc Fingers from Transcription Factor IIIA von Friesen, W J, Darby, M K

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Specific RNA Binding by a Single C2H2Zinc Finger von Friesen, Westley J., Darby, Martyn K.

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Tyr-129 is Important to the Peptide Ligand Affinity and Selectivity of Human Endothelin Type A Receptor von Lee, Jonathan A., Elliott, John D., Sutiphong, Joyce A., Friesen, Westley J., Ohlstein, Eliot H., Stadel, Jeffrey M., Gleason, John G., Peishoff, Catherine E.

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Specific RNA binding proteins constructed from zinc fingers von Darby, Martyn K, Friesen, Westley J

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Specific RNA binding by a single C2H2 zinc finger von Friesen, W J, Darby, M K

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Methods of screening for compounds for treating muscular dystrophy using human ALPHA7 integrin mRNA translation regulation von ZHUO JIN, WELCH ELLEN, FRIESEN WESTLEY J, NARYSHKIN NIKOLAI, ROMFO CHARLES, PATEL MEENAL, TOMIZAWA YUKI

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Methods of screening for compounds for treating muscular dystrophy using mIGF1 mRNA translation regulation von WELCH ELLEN, FRIESEN WESTLEY J, NARYSHKIN NIKOLAI, ROMFO CHARLES, PATEL MEENAL, TOMIZAWA YUKI, ZHOU JIN

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Methods of screening for compounds for treating muscular dystrophy using UTRN mRNA translation regulation von ZHUO JIN, WELCH ELLEN, FRIESEN WESTLEY J, NARYSHKIN NIKOLAI, ROMFO CHARLES, PATEL MEENAL, TOMIZAWA YUKI

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