Synthesis and In Vitro Evaluation of 8-Pyridinyl-Substituted Benzo[ e ]imidazo[2,1- c ][1,2,4]triazines as Phosphodiesterase 2A Inhibitors von Ritawidya, Rien, Ludwig, Friedrich-Alexander, Briel, Detlef, Brust, Peter, Scheunemann, Matthias

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[18F]Fluspidine—A PET Tracer for Imaging of σ1 Receptors in the Central Nervous System von Ludwig, Friedrich-Alexander, Laurini, Erik, Schmidt, Judith, Pricl, Sabrina, Deuther-Conrad, Winnie, Wünsch, Bernhard

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Role of TRPC6 in kidney damage after acute ischemic kidney injury von Zheng, Zhihuang, Tsvetkov, Dmitry, Bartolomaeus, Theda Ulrike Patricia, Erdogan, Cem, Krügel, Ute, Schleifenbaum, Johanna, Schaefer, Michael, Nürnberg, Bernd, Chai, Xiaoning, Ludwig, Friedrich-Alexander, N’diaye, Gabriele, Köhler, May-Britt, Wu, Kaiyin, Gollasch, Maik, Markó, Lajos

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A Pharmacokinetic and Metabolism Study of the TRPC6 Inhibitor SH045 in Mice by LC-MS/MS von Chai, Xiao-Ning, Ludwig, Friedrich-Alexander, Müglitz, Anne, Gong, Yuanyuan, Schaefer, Michael, Regenthal, Ralf, Krügel, Ute

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Structure–Affinity Relationships of Fluorinated Spirocyclic σ2 Receptor Ligands with an Exocyclic Benzylamino Moiety von Bergkemper, Melanie, Kronenberg, Elisabeth, Schepmann, Dirk, Ludwig, Friedrich‐Alexander, Brust, Peter, Wünsch, Bernhard

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Development of the High-Affinity Carborane-Based Cannabinoid Receptor Type 2 PET Ligand [18F]LUZ5-d8 von Ueberham, Lea, Gündel, Daniel, Kellert, Martin, Deuther-Conrad, Winnie, Ludwig, Friedrich-Alexander, Lönnecke, Peter, Kazimir, Aleksandr, Kopka, Klaus, Brust, Peter, Moldovan, Rareş-Petru, Hey-Hawkins, Evamarie

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Sigma-1 Receptor Positron Emission Tomography: A New Molecular Imaging Approach Using (S)-(-)-[F-18]Fluspidine in Glioblastoma von Toussaint, Magali, Deuther-Conrad, Winnie, Kranz, Mathias, Fischer, Steffen, Ludwig, Friedrich-Alexander, Juratli, Tareq A., Patt, Marianne, Wuensch, Bernhard, Schackert, Gabriele, Sabri, Osama, Brust, Peter

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The wheat species profiling by non-targeted UPLC–ESI–TOF-MS analysis von Stark, Timo D., Weiss, Patrick, Friedrich, Ludwig, Hofmann, Thomas

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Improved in vivo PET imaging of the adenosine A2A receptor in the brain using [18F]FLUDA, a deuterated radiotracer with high metabolic stability von Lai, Thu Hang, Toussaint, Magali, Teodoro, Rodrigo, Dukić-Stefanović, Sladjana, Gündel, Daniel, Ludwig, Friedrich-Alexander, Wenzel, Barbara, Schröder, Susann, Sattler, Bernhard, Moldovan, Rareş-Petru, Falkenburger, Björn H., Sabri, Osama, Deuther-Conrad, Winnie, Brust, Peter

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Radiosynthesis and Biological Investigation of a Novel Fluorine-18 Labeled Benzoimidazotriazine- Based Radioligand for the Imaging of Phosphodiesterase 2A with Positron Emission To... von Ritawidya, Rien, Wenzel, Barbara, Teodoro, Rodrigo, Toussaint, Magali, Kranz, Mathias, Deuther-Conrad, Winnie, Dukic-Stefanovic, Sladjana, Ludwig, Friedrich-Alexander, Scheunemann, Matthias, Brust, Peter

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Development of Novel Analogs of the Monocarboxylate Transporter Ligand FACH and Biological Validation of One Potential Radiotracer for Positron Emission Tomography (PET) Imaging von Sadeghzadeh, Masoud, Wenzel, Barbara, Guendel, Daniel, Deuther-Conrad, Winnie, Toussaint, Magali, Moldovan, Rares-Petru, Fischer, Steffen, Ludwig, Friedrich-Alexander, Teodoro, Rodrigo, Jonnalagadda, Shirisha, Jonnalagadda, Sravan K., Schueuermann, Gerrit, Mereddy, Venkatram R., Drewes, Lester R., Brust, Peter

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In vitro and in vivo evaluation of fluorinated indanone derivatives as potential positron emission tomography agents for the imaging of monoamine oxidase B in the brain von Dukić-Stefanović, Sladjana, Hang Lai, Thu, Toussaint, Magali, Clauß, Oliver, Jevtić, Ivana I., Penjišević, Jelena Z., Andrić, Deana, Ludwig, Friedrich-Alexander, Gündel, Daniel, Deuther-Conrad, Winnie, Kostić-Rajačić, Sladjana V., Brust, Peter, Teodoro, Rodrigo

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Exploring the Metabolism of (+)-[ 18 F]Flubatine in Vitro and in Vivo: LC-MS/MS Aided Identification of Radiometabolites in a Clinical PET Study von Ludwig, Friedrich-Alexander, Fischer, Steffen, Smits, René, Deuther-Conrad, Winnie, Hoepping, Alexander, Tiepolt, Solveig, Patt, Marianne, Sabri, Osama, Brust, Peter

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(+)-[18F]Flubatine as a novel α4β2 nicotinic acetylcholine receptor PET ligand—results of the first-in-human brain imaging application in patients with β-amyloid PET-confirmed Alzh... von Tiepolt, Solveig, Becker, Georg-Alexander, Wilke, Stephan, Cecchin, Diego, Rullmann, Michael, Meyer, Philipp M., Barthel, Henryk, Hesse, Swen, Patt, Marianne, Luthardt, Julia, Wagenknecht, Gudrun, Sattler, Bernhard, Deuther-Conrad, Winnie, Ludwig, Friedrich-Alexander, Fischer, Steffen, Gertz, Hermann-Josef, Smits, René, Hoepping, Alexander, Steinbach, Jörg, Brust, Peter, Sabri, Osama

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Development and Biological Evaluation of the First Highly Potent and Specific Benzamide-Based Radiotracer [ 18 F]BA3 for Imaging of Histone Deacetylases 1 and 2 in Brain von Clauß, Oliver, Schäker-Hübner, Linda, Wenzel, Barbara, Toussaint, Magali, Deuther-Conrad, Winnie, Gündel, Daniel, Teodoro, Rodrigo, Dukić-Stefanović, Sladjana, Ludwig, Friedrich-Alexander, Kopka, Klaus, Brust, Peter, Hansen, Finn K, Scheunemann, Matthias

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Structure-Affinity Relationships of Fluorinated Spirocyclic σ 2 Receptor Ligands with an Exocyclic Benzylamino Moiety von Bergkemper, Melanie, Kronenberg, Elisabeth, Schepmann, Dirk, Ludwig, Friedrich-Alexander, Brust, Peter, Wünsch, Bernhard

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Preclinical Incorporation Dosimetry of [18F]FACH—A Novel 18F-Labeled MCT1/MCT4 Lactate Transporter Inhibitor for Imaging Cancer Metabolism with PET von Sattler, Bernhard, Kranz, Mathias, Wenzel, Barbara, Jain, Nalin T., Moldovan, Rareş-Petru, Toussaint, Magali, Deuther-Conrad, Winnie, Ludwig, Friedrich-Alexander, Teodoro, Rodrigo, Sattler, Tatjana, Sadeghzadeh, Masoud, Sabri, Osama, Brust, Peter

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Comparison of in Silico, Electrochemical, in Vitro and in Vivo Metabolism of a Homologous Series of (Radio)fluorinated σ1 Receptor Ligands Designed for Positron Emission Tomography... von Wiese, Christian, Große Maestrup, Eva, Galla, Fabian, Schepmann, Dirk, Hiller, Achim, Fischer, Steffen, Ludwig, Friedrich-Alexander, Deuther-Conrad, Winnie, Donat, Cornelius K., Brust, Peter, Büter, Lars, Karst, Uwe, Wünsch, Bernhard

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LC-MS Supported Studies on the in Vitro Metabolism of both Enantiomers of Flubatine and the in Vivo Metabolism of (+)-[(18)F]Flubatine-A Positron Emission Tomography Radioligand fo... von Ludwig, Friedrich-Alexander, Smits, René, Fischer, Steffen, Donat, Cornelius K, Hoepping, Alexander, Brust, Peter, Steinbach, Jörg

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Validation of an LC-MS/MS Method to Quantify the New TRPC6 Inhibitor SH045 (Larixyl N-methylcarbamate) and Its Application in an Exploratory Pharmacokinetic Study in Mice von Chai, Xiao-Ning, Ludwig, Friedrich-Alexander, Mueglitz, Anne, Schaefer, Michael, Yin, Hai-Yan, Brust, Peter, Regenthal, Ralf, Krugel, Ute

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