Clinical Characteristics of Ovarian Cancer Classified by BRCA1, BRCA2 and RAD51C Status von Cunningham, J. M., Cicek, M. S., Larson, N. B., Davila, J., Wang, C., Larson, M. C., Song, H., Dicks, E. M., Harrington, P., Wick, M., Winterhoff, B. J., Hamidi, H., Konecny, G. E., Chien, J., Bibikova, M., Fan, J.-B., Kalli, K. R., Lindor, N. M., Fridley, B. L., Pharoah, P. P. D., Goode, E. L.

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The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population von Song, Honglin, Cicek, Mine S, Dicks, Ed, Harrington, Patricia, Ramus, Susan J, Cunningham, Julie M, Fridley, Brooke L, Tyrer, Jonathan P, Alsop, Jennifer, Jimenez-Linan, Mercedes, Gayther, Simon A, Goode, Ellen L, Pharoah, Paul D P

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Cell cycle genes and ovarian cancer susceptibility: a tagSNP analysis von Cunningham, J M, Vierkant, R A, Sellers, T A, Phelan, C, Rider, D N, Liebow, M, Schildkraut, J, Berchuck, A, Couch, F J, Wang, X, Fridley, B L, Gentry-Maharaj, A, Menon, U, Hogdall, E, Kjaer, S, Whittemore, A, DiCioccio, R, Song, H, Gayther, S A, Ramus, S J, Pharaoh, P D P, Goode, E L

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Genetic Breast Cancer Susceptibility Variants and Prognosis in the Prospectively Randomized SUCCESS A Study von Hein, A., Rack, B., Li, L., Ekici, A. B., Reis, A., Lux, M. P., Cunningham, J. M., Rübner, M., Fridley, B. L., Schneeweiss, A., Tesch, H., Lichtenegger, W., Fehm, T., Heinrich, G., Rezai, M., Beckmann, M W., Janni, W., Weinshilboum, R. M., Wang, L., Fasching, P. A., Häberle, L.

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Multivariate models to detect genomic signatures for a class of drugs: application to thiopurines pharmacogenomics von Fridley, B L, Jenkins, G D, Batzler, A, Wang, L, Ji, Y, Li, F, Weinshilboum, R M

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Obesity and survival among women with ovarian cancer: results from the Ovarian Cancer Association Consortium von Nagle, C M, Dixon, S C, Jensen, A, Kjaer, S K, Modugno, F, deFazio, A, Fereday, S, Hung, J, Johnatty, S E, Fasching, P A, Beckmann, M W, Lambrechts, D, Vergote, I, Van Nieuwenhuysen, E, Lambrechts, S, Risch, H A, Rossing, M A, Doherty, J A, Wicklund, K G, Chang-Claude, J, Goodman, M T, Ness, R B, Moysich, K, Heitz, F, du Bois, A, Harter, P, Schwaab, I, Matsuo, K, Hosono, S, Goode, E L, Vierkant, R A, Larson, M C, Fridley, B L, Høgdall, C, Schildkraut, J M, Weber, R P, Cramer, D W, Terry, K L, Bandera, E V, Paddock, L, Rodriguez-Rodriguez, L, Wentzensen, N, Yang, H P, Brinton, L A, Lissowska, J, Høgdall, E, Lundvall, L, Whittemore, A, McGuire, V, Sieh, W, Rothstein, J, Sutphen, R, Anton-Culver, H, Ziogas, A, Pearce, C L, Wu, A H, Webb, P M

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Gene set analysis of SNP data: benefits, challenges, and future directions von FRIDLEY, Brooke L, BIERNACKA, Joanna M

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Evidence for a time-dependent association between FOLR1 expression and survival from ovarian carcinoma: implications for clinical testing. An Ovarian Tumour Tissue Analysis consort... von Köbel, M, Madore, J, Ramus, S J, Clarke, B A, Pharoah, P D P, Deen, S, Bowtell, D D, Odunsi, K, Menon, U, Morrison, C, Lele, S, Bshara, W, Sucheston, L, Beckmann, M W, Hein, A, Thiel, F C, Hartmann, A, Wachter, D L, Anglesio, M S, Høgdall, E, Jensen, A, Høgdall, C, Kalli, K R, Fridley, B L, Keeney, G L, Fogarty, Z C, Vierkant, R A, Liu, S, Cho, S, Nelson, G, Ghatage, P, Gentry-Maharaj, A, Gayther, S A, Benjamin, E, Widschwendter, M, Intermaggio, M P, Rosen, B, Bernardini, M Q, Mackay, H, Oza, A, Shaw, P, Jimenez-Linan, M, Driver, K E, Alsop, J, Mack, M, Koziak, J M, Steed, H, Ewanowich, C, DeFazio, A, Chenevix-Trench, G, Fereday, S, Gao, B, Johnatty, S E, George, J, Galletta, L, Goode, E L, Kjær, S K, Huntsman, D G, Fasching, P A, Moysich, K B, Brenton, J D, Kelemen, L E

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Genome-wide association analyses of genetic, phenotypic, and environmental risks in the age-related eye disease study von Ryu, Euijung, Fridley, Brooke L, Tosakulwong, Nirubol, Bailey, Kent R, Edwards, Albert O

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Abstract 277: High agreement between immune profiling assays on the detection of infiltrating immune cells in ovarian tumor tissue von Ospina, Oscar E., Townsend, Mary K., Wang, Tianyi, Sasamoto, Naoko, Stewart, Paul, Conejo-Garcia, Jose, Terry, Kathryn, Tworoger, Shelley S., Fridley, B L.

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Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer von Hung, Rayjean J, Ulrich, Cornelia M, Goode, Ellen L, Brhane, Yonathan, Muir, Kenneth, Chan, Andrew T, Marchand, Loic Le, Schildkraut, Joellen, Witte, John S, Eeles, Rosalind, Boffetta, Paolo, Spitz, Margaret R, Poirier, Julia G, Rider, David N, Fridley, Brooke L, Chen, Zhihua, Haiman, Christopher, Schumacher, Fredrick, Easton, Douglas F, Landi, Maria Teresa, Brennan, Paul, Houlston, Richard, Christiani, David C, Field, John K, Bickeböller, Heike, Risch, Angela, Kote-Jarai, Zsofia, Wiklund, Fredrik, Grönberg, Henrik, Chanock, Stephen, Berndt, Sonja I, Kraft, Peter, Lindström, Sara, Al Olama, Ali Amin, Song, Honglin, Phelan, Catherine, Wentzensen, Nicholas, Peters, Ulrike, Slattery, Martha L, Sellers, Thomas A, Casey, Graham, Gruber, Stephen B, Hunter, David J, Amos, Christopher I, Henderson, Brian

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Mendelian randomization analyses suggest a role for cholesterol in the development of endometrial cancer von Kho, Pik‐Fang, Amant, Frederic, Annibali, Daniela, Ashton, Katie, Attia, John, Auer, Paul L., Beckmann, Matthias W., Black, Amanda, Brinton, Louise, Buchanan, Daniel D., Chanock, Stephen J., Chen, Chu, Chen, Maxine M., Cheng, Timothy H. T., Cook, Linda S., Crous‐Bous, Marta, Czene, Kamila, De Vivo, Immaculata, Dennis, Joe, Dörk, Thilo, Dowdy, Sean C., Dunning, Alison M., Dürst, Matthias, Easton, Douglas F., Ekici, Arif B., Fasching, Peter A., Fridley, Brooke L., Friedenreich, Christine M., García‐Closas, Montserrat, Gaudet, Mia M., Giles, Graham G., Goode, Ellen L., Gorman, Maggie, Haiman, Christopher A., Hall, Per, Hankinson, Susan E., Hein, Alexander, Hillemanns, Peter, Hodgson, Shirley, Hoivik, Erling A., Holliday, Elizabeth G., Hunter, David J., Jones, Angela, Kraft, Peter, Krakstad, Camilla, Lambrechts, Diether, Le Marchand, Loic, Liang, Xiaolin, Lindblom, Annika, Lissowska, Jolanta, Long, Jirong, Lu, Lingeng, Magliocco, Anthony M., Martin, Lynn, McEvoy, Mark, Milne, Roger L., Mints, Miriam, Nassir, Rami, Otton, Geoffrey, Palles, Claire, Pooler, Loreall, Proietto, Tony, Rebbeck, Timothy R., Renner, Stefan P., Risch, Harvey A., Rübner, Matthias, Runnebaum, Ingo, Sacerdote, Carlotta, Sarto, Gloria E., Schumacher, Fredrick, Scott, Rodney J., Setiawan, V. Wendy, Shah, Mitul, Sheng, Xin, Shu, Xiao‐Ou, Southey, Melissa C., Tham, Emma, Tomlinson, Ian, Trovik, Jone, Turman, Constance, Tyrer, Jonathan P., Van Den Berg, David, Wang, Zhaoming, Wentzensen, Nicolas, Xia, Lucy, Xiang, Yong‐Bing, Yang, Hannah P., Yu, Herbert, Zheng, Wei, Webb, Penelope M., Thompson, Deborah J., Spurdle, Amanda B., Glubb, Dylan M., O'Mara, Tracy A.

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Simultaneous Analysis of Multiple Data Types in Pharmacogenomic Studies Using Weighted Sparse Canonical Correlation Analysis von Chalise, Prabhakar, Batzler, Anthony, Abo, Ryan, Wang, Liewei, Fridley, Brooke L.

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Five endometrial cancer risk loci identified through genome-wide association analysis von Cheng, Timothy H T, Thompson, Deborah J, O'Mara, Tracy A, Painter, Jodie N, Glubb, Dylan M, Flach, Susanne, Lewis, Annabelle, French, Juliet D, Freeman-Mills, Luke, Church, David, Gorman, Maggie, Martin, Lynn, Hodgson, Shirley, Webb, Penelope M, Attia, John, Holliday, Elizabeth G, McEvoy, Mark, Scott, Rodney J, Henders, Anjali K, Martin, Nicholas G, Montgomery, Grant W, Nyholt, Dale R, Ahmed, Shahana, Healey, Catherine S, Shah, Mitul, Dennis, Joe, Fasching, Peter A, Beckmann, Matthias W, Hein, Alexander, Ekici, Arif B, Hall, Per, Czene, Kamila, Darabi, Hatef, Li, Jingmei, Dörk, Thilo, Dürst, Matthias, Hillemanns, Peter, Runnebaum, Ingo, Amant, Frederic, Schrauwen, Stefanie, Zhao, Hui, Lambrechts, Diether, Depreeuw, Jeroen, Dowdy, Sean C, Goode, Ellen L, Fridley, Brooke L, Winham, Stacey J, Njølstad, Tormund S, Salvesen, Helga B, Trovik, Jone, Werner, Henrica M J, Ashton, Katie, Otton, Geoffrey, Proietto, Tony, Liu, Tao, Mints, Miriam, Tham, Emma, Li, Mulin Jun, Yip, Shun H, Wang, Junwen, Bolla, Manjeet K, Michailidou, Kyriaki, Wang, Qin, Tyrer, Jonathan P, Dunlop, Malcolm, Houlston, Richard, Palles, Claire, Hopper, John L, Peto, Julian, Swerdlow, Anthony J, Burwinkel, Barbara, Brenner, Hermann, Meindl, Alfons, Brauch, Hiltrud, Lindblom, Annika, Chang-Claude, Jenny, Couch, Fergus J, Giles, Graham G, Kristensen, Vessela N, Cox, Angela, Cunningham, Julie M, Pharoah, Paul D P, Dunning, Alison M, Edwards, Stacey L, Easton, Douglas F, Tomlinson, Ian, Spurdle, Amanda B

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Abstract 4246: Comparison of pathology versus IHC-based ovarian carcinoma histology assignment using gene expression, DNA methylation, and clinical outcome data von Earp, M A., Winham, S J., Armasu, S M., Fridley, B L., Larson, M C., Fogarty, Z C., Kalli, K R., Wang, C, Keeney, G L., Cunningham, J M., Ramus, S, Kobel, M, Goode, E L.

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Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer risk von Painter, Jodie N, O'Mara, Tracy A, Batra, Jyotsna, Cheng, Timothy, Lose, Felicity A, Dennis, Joe, Michailidou, Kyriaki, Tyrer, Jonathan P, Ahmed, Shahana, Ferguson, Kaltin, Healey, Catherine S, Kaufmann, Susanne, Hillman, Kristine M, Walpole, Carina, Moya, Leire, Pollock, Pamela, Jones, Angela, Howarth, Kimberley, Martin, Lynn, Gorman, Maggie, Hodgson, Shirley, De Polanco, Ma Magdalena Echeverry, Sans, Monica, Carracedo, Angel, Castellvi-Bel, Sergi, Rojas-Martinez, Augusto, Santos, Erika, Teixeira, Manuel R, Carvajal-Carmona, Luis, Shu, Xiao-Ou, Long, Jirong, Zheng, Wei, Xiang, Yong-Bing, Montgomery, Grant W, Webb, Penelope M, Scott, Rodney J, McEvoy, Mark, Attia, John, Holliday, Elizabeth, Martin, Nicholas G, Nyholt, Dale R, Henders, Anjali K, Fasching, Peter A, Hein, Alexander, Beckmann, Matthias W, Renner, Stefan P, Dörk, Thilo, Hillemanns, Peter, Dürst, Matthias, Runnebaum, Ingo, Lambrechts, Diether, Coenegrachts, Lieve, Schrauwen, Stefanie, Amant, Frederic, Winterhoff, Boris, Dowdy, Sean C, Goode, Ellen L, Teoman, Attila, Salvesen, Helga B, Trovik, Jone, Njolstad, Tormund S, Werner, Henrica M J, Ashton, Katie, Proietto, Tony, Otton, Geoffrey, Tzortzatos, Gerasimos, Mints, Miriam, Tham, Emma, Hall, Per, Czene, Kamila, Liu, Jianjun, Li, Jingmei, Hopper, John L, Southey, Melissa C, Ekici, Arif B, Ruebner, Matthias, Johnson, Nicola, Peto, Julian, Burwinkel, Barbara, Marme, Frederik, Brenner, Hermann, Dieffenbach, Aida K, Meindl, Alfons, Brauch, Hiltrud, Lindblom, Annika, Depreeuw, Jeroen, Moisse, Matthieu, Chang-Claude, Jenny, Rudolph, Anja, Couch, Fergus J, Olson, Janet E, Giles, Graham G, Bruinsma, Fiona, Cunningham, Julie M, Fridley, Brooke L, Børresen-Dale, Anne-Lise, Kristensen, Vessela N, Cox, Angela, Swerdlow, Anthony J, Orr, Nicholas

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Investigation of Exomic Variants Associated with Overall Survival in Ovarian Cancer von Winham, S. J, Pirie, A, Chen, Y. A, Larson, M. C, Fogarty, Z. C, Earp, M. A, Anton-Culver, H, Bandera, E. V, Cramer, Daniel William, Doherty, J. A, Goodman, M. T, Gronwald, J, Karlan, B. Y, Kjaer, S. K, Levine, D. A, Menon, U, Ness, R. B, Pearce, C. L, Pejovic, T, Rossing, M. A, Wentzensen, N, Bean, Y. T, Bisogna, M, Brinton, L. A, Carney, M. E, Cunningham, J. M, Cybulski, C, deFazio, A, Dicks, E. M, Edwards, R. P, Gayther, S. A, Gentry-Maharaj, A, Gore, M, Iversen, E. S, Jensen, A, Johnatty, S. E, Lester, J, Lin, H.-Y, Lissowska, J, Lubinski, J, Menkiszak, J, Modugno, F, Moysich, K. B, Orlow, I, Pike, M. C, Ramus, S. J, Song, H, Terry, Kathryn Lynne, Thompson, P. J, Tyrer, J. P, van den Berg, D. J, Vierkant, R. A, Vitonis, A. F, Walsh, C, Wilkens, L. R, Wu, A. H, Yang, H, Ziogas, A, Berchuck, A, Schildkraut, J. M, Permuth-Wey, J, Phelan, C. M, Pharoah, P. D. P, Fridley, B. L, Sellers, T. A, Goode, E. L

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Network-Based Integration of GWAS and Gene Expression Identifies a HOX-Centric Network Associated with Serous Ovarian Cancer Risk von Kar, S. P, Li, Qiyuan, Anton-Culver, H, Antonenkova, N, Chenevix-Trench, G, Baker, H, Bandera, E. V, Bean, Y. T, Beckmann, M. W, Bisogna, M, Bjorge, L, Brooks-Wilson, A, Campbell, I, Chang-Claude, J, Chen, Y. A, Cook, L. S, Cramer, Daniel William, Dansonka-Mieszkowska, A, Dennis, J, Dicks, E, Dork, T, du Bois, A, Durst, M, Easton, D. F, Ekici, A. B, Gao, Y.-T, Gentry-Maharaj, A, Giles, G. G, Goode, E. L, Goodman, M. T, Grownwald, J, Harrington, P, Hein, A, Heitz, F, Hildebrandt, M. A. T, Hillemanns, P, Karlan, B. Y, Kelemen, L. E, Kelley, J, Kiemeney, L. A, Krakstad, C, Kupryjanczyk, J, Lambrechts, D, Le, N. D, Lee, A. W, Leminen, A, Liang, D, Lissowska, J, Lu, K, Lubinski, J, Lundvall, L, Matsuo, K, McLaughlin, J. R, Menon, U, Moysich, K. B, Nedergaard, L, Ness, R. B, Nevanlinna, H, Odunsi, K, Olson, S. H, Orsulic, S, Weber, R. P, Pearce, C. L, Pejovic, T, Permuth-Wey, J, Phelan, C. M, Pike, M. C, Risch, H. A, Rossing, M. A, Runnebaum, I. B, Rzepecka, I. K, Salvesen, H. B, Schildkraut, J. M, Schwaab, I, Shu, X.-O, Shvetsov, Y. B, Siddiqui, N, Song, H, Sucheston-Campbell, L. E, Teo, S.-H, Thompson, P. J, Tsai, Y.-Y, Tworoger, Shelley Slate, van Altena, A. M, Van Nieuwenhuysen, E, Vierkant, R. A, Wang-Gohrke, S, Walsh, C, Whittemore, A. S, Wilkens, L. R, Woo, Y.-L, Wu, X, Wu, A, Yang, H, Zheng, W, Ziogas, A, Sellers, T. A, Freedman, M. L, Gayther, S. A, Pharoah, P. D. P

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Genome-wide Analysis Identifies Novel Loci Associated with Ovarian Cancer Outcomes: Findings from the Ovarian Cancer Association Consortium von Johnatty, S. E, Tyrer, J. P, Kar, S, Beesley, J, Lu, Y, Gao, B, Fasching, P. A, Hein, A, Ekici, A. B, Beckmann, M. W, Lambrechts, D, Van Nieuwenhuysen, E, Vergote, I, Lambrechts, S, Rossing, M. A, Doherty, J. A, Chang-Claude, J, Modugno, F, Ness, R. B, Moysich, K. B, Levine, D. A, Kiemeney, L. A, Massuger, L. F. A. G, Lubinski, J, Jakubowska, A, Cybulski, C, Brinton, L, Lissowska, J, Wentzensen, N, Song, H, Rhenius, V, Campbell, I, Eccles, D, Sieh, W, Whittemore, A. S, McGuire, V, Rothstein, J. H, Sutphen, R, Anton-Culver, H, Ziogas, A, Gayther, S. A, Gentry-Maharaj, A, Menon, U, Ramus, S. J, Pearce, C. L, Pike, M. C, Stram, D. O, Wu, A. H, Kupryjanczyk, J, Dansonka-Mieszkowska, A, Rzepecka, I. K, Spiewankiewicz, B, Goodman, M. T, Wilkens, L. R, Carney, M. E, Thompson, P. J, Heitz, F, du Bois, A, Schwaab, I, Harter, P, Pisterer, J, Hillemanns, P, Karlan, B. Y, Walsh, C, Lester, J, Orsulic, S, Winham, S. J, Earp, M, Larson, M. C, Fogarty, Z. C, Jensen, A, Kjaer, S. K, Fridley, B. L, Cunningham, J. M, Vierkant, R. A, Schildkraut, J. M, Iversen, E. S, Terry, Kathryn Lynne, Cramer, Daniel William, Bandera, E. V, Orlow, I, Pejovic, T, Bean, Y, Hogdall, C, Lundvall, L, McNeish, I, Paul, J, Carty, K, Siddiqui, N, Glasspool, R, Sellers, T, Kennedy, C, Chiew, Y.-E, Berchuck, A, MacGregor, S, Pharoah, P. D. P, Goode, E. L, deFazio, A, Webb, P. M, Chenevix-Trench, G

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Candidate locus analysis of the TERT–CLPTM1L cancer risk region on chromosome 5p15 identifies multiple independent variants associated with endometrial cancer risk von Carvajal-Carmona, Luis G., O’Mara, Tracy A., Painter, Jodie N., Lose, Felicity A., Dennis, Joe, Michailidou, Kyriaki, Tyrer, Jonathan P., Ahmed, Shahana, Ferguson, Kaltin, Healey, Catherine S., Pooley, Karen, Beesley, Jonathan, Cheng, Timothy, Jones, Angela, Howarth, Kimberley, Martin, Lynn, Gorman, Maggie, Hodgson, Shirley, Wentzensen, Nicholas, Fasching, Peter A., Hein, Alexander, Beckmann, Matthias W., Renner, Stefan P., Dörk, Thilo, Hillemanns, Peter, Dürst, Matthias, Runnebaum, Ingo, Lambrechts, Diether, Coenegrachts, Lieve, Schrauwen, Stefanie, Amant, Frederic, Winterhoff, Boris, Dowdy, Sean C., Goode, Ellen L., Teoman, Attila, Salvesen, Helga B., Trovik, Jone, Njolstad, Tormund S., Werner, Henrica M. J., Scott, Rodney J., Ashton, Katie, Proietto, Tony, Otton, Geoffrey, Wersäll, Ofra, Mints, Miriam, Tham, Emma, Hall, Per, Czene, Kamila, Liu, Jianjun, Li, Jingmei, Hopper, John L., Southey, Melissa C., Ekici, Arif B., Ruebner, Matthias, Johnson, Nichola, Peto, Julian, Burwinkel, Barbara, Marme, Frederik, Brenner, Hermann, Dieffenbach, Aida K., Meindl, Alfons, Brauch, Hiltrud, Lindblom, Annika, Depreeuw, Jeroen, Moisse, Matthieu, Chang-Claude, Jenny, Rudolph, Anja, Couch, Fergus J., Olson, Janet E., Giles, Graham G., Bruinsma, Fiona, Cunningham, Julie M., Fridley, Brooke L., Børresen-Dale, Anne-Lise, Kristensen, Vessela N., Cox, Angela, Swerdlow, Anthony J., Orr, Nicholas, Bolla, Manjeet K., Wang, Qin, Weber, Rachel Palmieri, Chen, Zhihua, Shah, Mitul, Pharoah, Paul D. P., Dunning, Alison M., Tomlinson, Ian, Easton, Douglas F., Spurdle, Amanda B., Thompson, Deborah J.

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