WNT Signaling in Hematological Malignancies von Frenquelli, Michela, Tonon, Giovanni

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ATR addiction in multiple myeloma: synthetic lethal approaches exploiting established therapies von Botrugno, Oronza A, Bianchessi, Silvia, Zambroni, Desirée, Frenquelli, Michela, Belloni, Daniela, Bongiovanni, Lucia, Girlanda, Stefania, Di Terlizzi, Simona, Ferrarini, Marina, Ferrero, Elisabetta, Ponzoni, Maurilio, Marcatti, Magda, Tonon, Giovanni

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MicroRNA and proliferation control in chronic lymphocytic leukemia: functional relationship between miR-221/222 cluster and p27 von Frenquelli, Michela, Muzio, Marta, Scielzo, Cristina, Fazi, Claudia, Scarfò, Lydia, Rossi, Claudia, Ferrari, Giuliana, Ghia, Paolo, Caligaris-Cappio, Federico

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Histone demethylase JARID1C inactivation triggers genomic instability in sporadic renal cancer von Rondinelli, Beatrice, Rosano, Dalia, Antonini, Elena, Frenquelli, Michela, Montanini, Laura, Huang, DaChuan, Segalla, Simona, Yoshihara, Kosuke, Amin, Samir B, Lazarevic, Dejan, The, Bin Tean, Verhaak, Roel G W, Futreal, P Andrew, Di Croce, Luciano, Chin, Lynda, Cittaro, Davide, Tonon, Giovanni

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Iron increases the susceptibility of multiple myeloma cells to bortezomib von Campanella, Alessandro, Santambrogio, Paolo, Fontana, Francesca, Frenquelli, Michela, Cenci, Simone, Marcatti, Magda, Sitia, Roberto, Tonon, Giovanni, Camaschella, Clara

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P1225: CYLD, A NOVEL REGULATOR OF SPLENIC MARGINAL ZONE LYMPHOMA PATHOGENESIS von Pseftogkas, Athanasios, Bordini, Jessica, Frenquelli, Michela, Bonfiglio, Ferdinando, Daibata, Masanori, Ángel Martínez‐Climent, José, Mosialos, George, Rossi, Davide, Campanella, Alessandro, Xanthopoulos, Konstantinos, Ghia, Paolo

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P1222: ANTIGEN‐INDEPENDENT, CELL‐AUTONOMOUS SIGNALING IN SPLENIC MARGINAL ZONE LYMPHOMA von Iatrou, Anastasia, Maity, Palash C, Theresa Linder, Alexandra, Agathangelidis, Andreas, Frenquelli, Michela, Sandaltzopoulos, Raphael, Degano, Massimo, Chatzidimitriou, Anastasia, Ghia, Paolo, Jumaa, Hassan, Stamatopoulos, Kostas

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P605: IMMUNOGENETICS AND ANTIGEN REACTIVITY PROFILING CONTRIBUTE TO UNRAVELLING THE ONTOGENY OF CLL STEREOTYPED SUBSET #4 von Iatrou, Anastasia, Sofou, Electra, Kotroni, Eleni, Ann Sutton, Lesley, Frenquelli, Michela, Sandaltzopoulos, Raphael, Sakellari, Ioanna, Stavrogianni, Niki, Psomopoulos, Fotis, Ghia, Paolo, Rosenquist, Richard, Agathangelidis, Andreas, Chatzidimitriou, Anastasia, Stamatopoulos, Kostas

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P1489: HIGH DOSE IRON IMPAIRS MALIGNANT B‐CELL VIABILITY AND IMPROVES IMMUNE ANTITUMOR FUNCTIONS IN CHRONIC LYMPHOCYTIC LEUKEMIA von Bordini, Jessica, Morabito, Alessia, Taccetti, Caterina, Lenzi, Chiara, Ranghetti, Pamela, Perotta, Eleonora, Frenquelli, Michela, Scarfò, Lydia, Albi, Elisa, Ghia, Paolo, Campanella, Alessandro

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P1517: HUMORAL AND CELLULAR IMMUNE RESPONSES TO SARS‐COV‐2 NATURAL INFECTION OR VACCINATION IN PATIENTS WITH CHRONIC LYMPHOCYTIC LEUKEMIA (CLL): A STUDY BY ERIC, THE EUROPEAN RESEA... von Campanella, Alessandro, Capasso, Antonella, Taccetti, Caterina, Heltai, Silvia, Albi, Elisa, Herishanu, Yair, Haggenburg, Sabine, Chatzikonstantinou, Thomas, Doubek, Michael, Kättström, Magdalena, Giannopoulos, Krzysztof, Simkovic, Martin, Moreno, Carol, Massaia, Massimo, Bumbea, Horia, Shimmari, Salem Al, Ranghetti, Pamela, Perotta, Eleonora, Martini, Francesca, Sant’antonio, Emanuela, Colia, Maria, Combi, Catalina, Levi, Shai, Kater, Arnon, Hazenberg, Mette, Nijhof, Inger, Hofsink, Quincy, Demosthenous, Christos, Kotaskova, Jana, Zaleska, Joanna, Vrbacky, Filip, Mora, Alba, Bisogno, Davide, Tripoli, Ignazio Ezio, Popov, Viola Maria, Roman, Viviana, Scarano, Eloise, Frenquelli, Michela, Scarfò, Lydia, Stamatopoulos, Kostas, Ghia, Paolo

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From normal to clonal B cells: Chronic lymphocytic leukemia (CLL) at the crossroad between neoplasia and autoimmunity von Ghia, Paolo, Scielzo, Cristina, Frenquelli, Michela, Muzio, Marta, Caligaris-Cappio, Federico

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Constitutive activation of distinct BCR-signaling pathways in a subset of CLL patients: a molecular signature of anergy von Muzio, Marta, Apollonio, Benedetta, Scielzo, Cristina, Frenquelli, Michela, Vandoni, Irene, Boussiotis, Vassiliki, Caligaris-Cappio, Federico, Ghia, Paolo

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Evidence of Defective Cell-Autonomous Signalling By B Cell Receptors in CLL Stereotyped Subset #1 von Minici, Claudia, Cocomazzi, Paolo G., Akpınaroğlu, Can, Iatrou, Anastasia, Gounari, Maria, Frenquelli, Michela, Scarfo, Lydia, Buske, Christian, Agathangelidis, Andreas, Jumaa, Hassan, Maity, Palash, Ghia, Paolo, Stamatopoulos, Kostas, Degano, Massimo

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Tumor suppressor PNRC1 blocks rRNA maturation by recruiting the decapping complex to the nucleolus von Gaviraghi, Marco, Vivori, Claudia, Pareja Sanchez, Yerma, Invernizzi, Francesca, Cattaneo, Angela, Santoliquido, Benedetta Maria, Frenquelli, Michela, Segalla, Simona, Bachi, Angela, Doglioni, Claudio, Pelechano, Vicent, Cittaro, Davide, Tonon, Giovanni

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IκBε deficiency accelerates disease development in chronic lymphocytic leukemia von Bordini, Jessica, Lenzi, Chiara, Frenquelli, Michela, Morabito, Alessia, Pseftogas, Athanasios, Belloni, Daniela, Mansouri, Larry, Tsiolas, George, Perotta, Eleonora, Ranghetti, Pamela, Gandini, Francesca, Genova, Francesca, Hägerstrand, Daniel, Gavriilidis, Georgios, Keisaris, Sofoklis, Pechlivanis, Nikolaos, Davi, Frederic, Kay, Neil E., Langerak, Anton W., Pospisilova, Sarka, Scarfò, Lydia, Makris, Antonios, Psomopoulos, Fotis E., Stamatopoulos, Kostas, Rosenquist, Richard, Campanella, Alessandro, Ghia, Paolo

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H3K4me3 demethylation by the histone demethylase KDM5C/JARID1C promotes DNA replication origin firing von Rondinelli, Beatrice, Schwerer, Hélène, Antonini, Elena, Gaviraghi, Marco, Lupi, Alessio, Frenquelli, Michela, Cittaro, Davide, Segalla, Simona, Lemaitre, Jean-Marc, Tonon, Giovanni

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CLL-461 Humoral Response to COVID-19 Vaccine: A Challenge in CLL von Capasso, Antonella, Albi, Elisa, Schiattone, Luana, Martini, Francesca, Sant'Antonio, Emanuela, Scarfò, Lydia, Ranghetti, Pamela, Frenquelli, Michela, Campanella, Alessandro, Perotta, Eleonora, Heltai, Silvia, Colia, Maria, Ghia, Paolo

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Poster: CLL-461 Humoral Response to COVID-19 Vaccine: A Challenge in CLL von Capasso, Antonella, Albi, Elisa, Schiattone, Luana, Martini, Francesca, Sant'Antonio, Emanuela, Scarfò, Lydia, Ranghetti, Pamela, Frenquelli, Michela, Campanella, Alessandro, Perotta, Eleonora, Heltai, Silvia, Colia, Maria, Ghia, Paolo

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Tumor suppressor PNRC 1 blocks r RNA maturation by recruiting the decapping complex to the nucleolus von Gaviraghi, Marco, Vivori, Claudia, Pareja Sanchez, Yerma, Invernizzi, Francesca, Cattaneo, Angela, Santoliquido, Benedetta Maria, Frenquelli, Michela, Segalla, Simona, Bachi, Angela, Doglioni, Claudio, Pelechano, Vicent, Cittaro, Davide, Tonon, Giovanni

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Expression and function of toll like receptors in chronic lymphocytic leukaemia cells von Muzio, Marta, Scielzo, Cristina, Bertilaccio, Maria T. S., Frenquelli, Michela, Ghia, Paolo, Caligaris‐Cappio, Federico

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