The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Outcomes and Metrics of Pharmacogenetic Implementations Across Diverse Healthcare Systems von Luzum, JA, Pakyz, RE, Elsey, AR, Haidar, CE, Peterson, JF, Whirl‐Carrillo, M, Handelman, SK, Palmer, K, Pulley, JM, Beller, M, Schildcrout, JS, Field, JR, Weitzel, KW, Cooper‐DeHoff, RM, Cavallari, LH, O'Donnell, PH, Altman, RB, Pereira, N, Ratain, MJ, Roden, DM, Embi, PJ, Sadee, W, Klein, TE, Johnson, JA, Relling, MV, Wang, L, Weinshilboum, RM, Shuldiner, AR, Freimuth, RR

Volltext

Standardizing terms for clinical pharmacogenetic test results: consensus terms from the Clinical Pharmacogenetics Implementation Consortium (CPIC) von Caudle, Kelly E., Dunnenberger, Henry M., Freimuth, Robert R., Peterson, Josh F., Burlison, Jonathan D., Whirl-Carrillo, Michelle, Scott, Stuart A., Rehm, Heidi L., Williams, Marc S., Klein, Teri E., Relling, Mary V., Hoffman, James M.

Volltext

Pharmacogenetic allele nomenclature: International workgroup recommendations for test result reporting von Kalman, LV, Agúndez, JAG, Appell, M Lindqvist, Black, JL, Bell, GC, Boukouvala, S, Bruckner, C, Bruford, E, Caudle, K, Coulthard, SA, Daly, AK, Tredici, AL Del, den Dunnen, JT, Drozda, K, Everts, RE, Flockhart, D, Freimuth, RR, Gaedigk, A, Hachad, H, Hartshorne, T, Ingelman-Sundberg, M, Klein, TE, Lauschke, VM, Maglott, DR, McLeod, HL, McMillin, GA, Meyer, UA, Müller, DJ, Nickerson, DA, Oetting, WS, Pacanowski, M, Pratt, VM, Relling, MV, Roberts, A, Rubinstein, WS, Sangkuhl, K, Schwab, M, Scott, SA, Sim, SC, Thirumaran, RK, Toji, LH, Tyndale, RF, van Schaik, RHN, Whirl-Carrillo, M, Yeo, KTJ, Zanger, UM

Volltext

The Pharmacogenomics Research Network Translational Pharmacogenetics Program: Overcoming Challenges of Real-World Implementation von Shuldiner, A R, Relling, M V, Peterson, J F, Hicks, K, Freimuth, R R, Sadee, W, Pereira, N L, Roden, D M, Johnson, J A, Klein, T E

Volltext

Clinical Pharmacogenetics Implementation Consortium Guidelines for HLA-B Genotype and Abacavir Dosing: 2014 Update von Martin, M A, Hoffman, J M, Freimuth, R R, Klein, T E, Dong, B J, Pirmohamed, M, Hicks, J K, Wilkinson, M R, Haas, D W, Kroetz, D L

Volltext

Development and use of active clinical decision support for preemptive pharmacogenomics von Bell, Gillian C, Crews, Kristine R, Wilkinson, Mark R, Haidar, Cyrine E, Hicks, J Kevin, Baker, Donald K, Kornegay, Nancy M, Yang, Wenjian, Cross, Shane J, Howard, Scott C, Freimuth, Robert R, Evans, William E, Broeckel, Ulrich, Relling, Mary V, Hoffman, James M

Volltext

Participant choices for return of genomic results in the eMERGE Network von Hoell, Christin, Wynn, Julia, Rasmussen, Luke V., Marsolo, Keith, Aufox, Sharon A., Chung, Wendy K., Connolly, John J., Freimuth, Robert R., Kochan, David, Hakonarson, Hakon, Harr, Margaret, Holm, Ingrid A., Kullo, Iftikhar J., Lammers, Philip E., Leppig, Kathleen A., Leslie, Nancy D., Myers, Melanie F., Sharp, Richard R., Smith, Maureen E., Prows, Cynthia A.

Volltext

SNP interaction detection with Random Forests in high-dimensional genetic data von Winham, Stacey J, Colby, Colin L, Freimuth, Robert R, Wang, Xin, de Andrade, Mariza, Huebner, Marianne, Biernacka, Joanna M

Volltext

Genomic Information for Clinicians in the Electronic Health Record: Lessons Learned From the Clinical Genome Resource Project and the Electronic Medical Records and Genomics Networ... von Williams, Marc S, Taylor, Casey Overby, Walton, Nephi A, Goehringer, Scott R, Aronson, Samuel, Freimuth, Robert R, Rasmussen, Luke V, Hall, Eric S, Prows, Cynthia A, Chung, Wendy K, Fedotov, Alexander, Nestor, Jordan, Weng, Chunhua, Rowley, Robb K, Wiesner, Georgia L, Jarvik, Gail P, Del Fiol, Guilherme

Volltext

A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer von Wagner, Alex H., Walsh, Brian, Mayfield, Georgia, Tamborero, David, Sonkin, Dmitriy, Krysiak, Kilannin, Deu-Pons, Jordi, Duren, Ryan P., Gao, Jianjiong, McMurry, Julie, Patterson, Sara, del Vecchio Fitz, Catherine, Pitel, Beth A., Sezerman, Ozman U., Ellrott, Kyle, Warner, Jeremy L., Rieke, Damian T., Aittokallio, Tero, Cerami, Ethan, Ritter, Deborah I., Schriml, Lynn M., Freimuth, Robert R., Haendel, Melissa, Raca, Gordana, Madhavan, Subha, Baudis, Michael, Beckmann, Jacques S., Dienstmann, Rodrigo, Chakravarty, Debyani, Li, Xuan Shirley, Mockus, Susan, Elemento, Olivier, Schultz, Nikolaus, Lopez-Bigas, Nuria, Lawler, Mark, Goecks, Jeremy, Griffith, Malachi, Griffith, Obi L., Margolin, Adam A.

Volltext

Implementing Genomic Clinical Decision Support for Drug‐Based Precision Medicine von Freimuth, RR, Formea, CM, Hoffman, JM, Matey, E, Peterson, JF, Boyce, RD

Volltext

The GA4GH Variation Representation Specification: A computational framework for variation representation and federated identification von Wagner, Alex H., Babb, Lawrence, Alterovitz, Gil, Baudis, Michael, Brush, Matthew, Cameron, Daniel L., Cline, Melissa, Griffith, Malachi, Griffith, Obi L., Hunt, Sarah E., Kreda, David, Lee, Jennifer M., Li, Stephanie, Lopez, Javier, Moyer, Eric, Nelson, Tristan, Patel, Ronak Y., Riehle, Kevin, Robinson, Peter N., Rynearson, Shawn, Schuilenburg, Helen, Tsukanov, Kirill, Walsh, Brian, Konopko, Melissa, Rehm, Heidi L., Yates, Andrew D., Freimuth, Robert R., Hart, Reece K.

Volltext

Preemptive Genotyping for Personalized Medicine: Design of the Right Drug, Right Dose, Right Time—Using Genomic Data to Individualize Treatment Protocol von Bielinski, Suzette J., PhD, MEd, Olson, Janet E., PhD, Pathak, Jyotishman, PhD, Weinshilboum, Richard M., MD, Wang, Liewei, MD, PhD, Lyke, Kelly J, Ryu, Euijung, PhD, Targonski, Paul V., MD, PhD, Van Norstrand, Michael D., MD, PhD, Hathcock, Matthew A., MS, Takahashi, Paul Y., MD, McCormick, Jennifer B., PhD, MPP, Johnson, Kiley J., MS, CGC, Maschke, Karen J., PhD, Rohrer Vitek, Carolyn R., MS, Ellingson, Marissa S., MS, CGC, Wieben, Eric D., PhD, Farrugia, Gianrico, MD, Morrisette, Jody A., MBA, Kruckeberg, Keri J., BA, Bruflat, Jamie K., MS, Peterson, Lisa M., BS, Blommel, Joseph H., MS, Skierka, Jennifer M., BS, Ferber, Matthew J., PhD, Black, John L., MD, Baudhuin, Linnea M., PhD, Klee, Eric W., PhD, Ross, Jason L., MA, Veldhuizen, Tamra L., BS, Schultz, Cloann G., MS, Caraballo, Pedro J., MD, Freimuth, Robert R., PhD, Chute, Christopher G., MD, DrPH, Kullo, Iftikhar J., MD

Volltext

Under-specification as the source of ambiguity and vagueness in narrative phenotype algorithm definitions von Yu, Jingzhi, Pacheco, Jennifer A, Ghosh, Anika S, Luo, Yuan, Weng, Chunhua, Shang, Ning, Benoit, Barbara, Carrell, David S, Carroll, Robert J, Dikilitas, Ozan, Freimuth, Robert R, Gainer, Vivian S, Hakonarson, Hakon, Hripcsak, George, Kullo, Iftikhar J, Mentch, Frank, Murphy, Shawn N, Peissig, Peggy L, Ramirez, Andrea H, Walton, Nephi, Wei, Wei-Qi, Rasmussen, Luke V

Volltext

Leveraging a pharmacogenomics knowledgebase to formulate a drug response phenotype terminology for genomic medicine von Zhao, Yiqing, Brush, Matthew, Wang, Chen, Wagner, Alex H, Liu, Hongfang, Freimuth, Robert R

Volltext

Pharmacogenomic assessment of carboxylesterases 1 and 2 von Marsh, Sharon, Xiao, Ming, Yu, Jinsheng, Ahluwalia, Ranjeet, Minton, Matthew, Freimuth, Robert R., Kwok, Pui-Yan, McLeod, Howard L.

Volltext

Recommendations for the safe, effective use of adaptive CDS in the US healthcare system: an AMIA position paper von Petersen, Carolyn, Smith, Jeffery, Freimuth, Robert R, Goodman, Kenneth W, Jackson, Gretchen Purcell, Kannry, Joseph, Liu, Hongfang, Madhavan, Subha, Sittig, Dean F, Wright, Adam

Volltext

Human cytosolic sulfotransferase database mining: identification of seven novel genes and pseudogenes von Freimuth, R R, Wiepert, M, Chute, C G, Wieben, E D, Weinshilboum, R M

Volltext

ClinGen Allele Registry links information about genetic variants von Pawliczek, Piotr, Patel, Ronak Y., Ashmore, Lillian R., Jackson, Andrew R., Bizon, Chris, Nelson, Tristan, Powell, Bradford, Freimuth, Robert R., Strande, Natasha, Shah, Neethu, Paithankar, Sameer, Wright, Matt W., Dwight, Selina, Zhen, Jimmy, Landrum, Melissa, McGarvey, Peter, Babb, Larry, Plon, Sharon E., Milosavljevic, Aleksandar

Volltext

Developing knowledge resources to support precision medicine: principles from the Clinical Pharmacogenetics Implementation Consortium (CPIC) von Hoffman, James M, Dunnenberger, Henry M, Kevin Hicks, J, Caudle, Kelly E, Whirl Carrillo, Michelle, Freimuth, Robert R, Williams, Marc S, Klein, Teri E, Peterson, Josh F

Volltext