Inducible FGFR-1 Activation Leads to Irreversible Prostate Adenocarcinoma and an Epithelial-to-Mesenchymal Transition von Acevedo, Victor D., Gangula, Rama D., Freeman, Kevin W., Li, Rile, Zhang, Youngyou, Wang, Fen, Ayala, Gustavo E., Peterson, Leif E., Ittmann, Michael, Spencer, David M.

Volltext

Large 1p36 Deletions Affecting Arid1a Locus Facilitate Mycn-Driven Oncogenesis in Neuroblastoma von García-López, Jesus, Wallace, Kirby, Otero, Joel H., Olsen, Rachelle, Wang, Yong-dong, Finkelstein, David, Gudenas, Brian L., Rehg, Jerold E., Northcott, Paul, Davidoff, Andrew M., Freeman, Kevin W.

Volltext

Therapeutically targeting oncogenic CRCs facilitates induced differentiation of NB by RA and the BET bromodomain inhibitor von Alleboina, Satyanarayana, Aljouda, Nour, Miller, Mellessa, Freeman, Kevin W.

Volltext

XPO1 inhibition with selinexor synergizes with proteasome inhibition in neuroblastoma by targeting nuclear export of IkB von Galinski, Basia, Luxemburg, Marcus, Landesman, Yosef, Pawel, Bruce, Johnson, Katherine J., Master, Stephen R., Freeman, Kevin W., Loeb, David M., Hébert, Jean M., Weiser, Daniel A.

Volltext

Antagonizing Bcl-2 family members sensitizes neuroblastoma and Ewing's sarcoma to an inhibitor of glutamine metabolism von Olsen, Rachelle R, Mary-Sinclair, Michelle N, Yin, Zhirong, Freeman, Kevin W

Volltext

A cell motility screen reveals role for MARCKS-related protein in adherens junction formation and tumorigenesis von Finlayson, Alexander E, Freeman, Kevin W

Volltext

Transcription factor 4 is a key mediator of oncogenesis in neuroblastoma by promoting MYC activity von Aljouda, Nour A, Shrestha, Dewan, DeVaux, Chelsea, Olsen, Rachelle R, Alleboina, Satyanarayana, Walker, Megan, Cheng, Yong, Freeman, Kevin W

Volltext

Bromodomain-Selective BET Inhibitors Are Potent Antitumor Agents against MYC-Driven Pediatric Cancer von Slavish, P Jake, Chi, Liying, Yun, Mi-Kyung, Tsurkan, Lyudmila, Martinez, Nancy E, Jonchere, Barbara, Chai, Sergio C, Connelly, Michele, Waddell, M Brett, Das, Sourav, Neale, Geoffrey, Li, Zhenmei, Shadrick, William R, Olsen, Rachelle R, Freeman, Kevin W, Low, Jonathan A, Price, Jeanine E, Young, Brandon M, Bharatham, Nagakumar, Boyd, Vincent A, Yang, Jun, Lee, Richard E, Morfouace, Marie, Roussel, Martine F, Chen, Taosheng, Savic, Daniel, Guy, R Kiplin, White, Stephen W, Shelat, Anang A, Potter, Philip M

Volltext

Synthetic Activation of Caspases: Artificial Death Switches von MacCorkle, Rebecca A., Freeman, Kevin W., Spencer, David M.

Volltext

Regenerative protein thymosin β-4 is a novel regulator of purinergic signaling von Freeman, Kevin W, Bowman, Brian R, Zetter, Bruce R

Volltext

Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma von Abu-Zaid, Ahmed, Fang, Jie, Jin, Hongjian, Singh, Shivendra, Pichavaram, Prahalathan, Wu, Qiong, Tillman, Heather, Janke, Laura, Rosikiewicz, Wojciech, Xu, Beisi, Van De Velde, Lee-Ann, Guo, Yian, Li, Yimei, Shendy, Noha A.M., Delahunty, Ian M., Rankovic, Zoran, Chen, Taosheng, Chen, Xiang, Freeman, Kevin W., Hatley, Mark E., Durbin, Adam D., Murray, Peter J., Murphy, Andrew J., Thomas, Paul G., Davidoff, Andrew M., Yang, Jun

Volltext

Inducible Dimerization of FGFR1: Development of a Mouse Model to Analyze Progressive Transformation of the Mammary Gland von Welm, Bryan E., Freeman, Kevin W., Chen, Mercy, Contreras, Alejandro, Spencer, David M., Rosen, Jeffrey M.

Volltext

Inducible prostate intraepithelial neoplasia with reversible hyperplasia in conditional FGFR1-expressing mice von FREEMAN, Kevin W, WELM, Bryan E, GANGULA, Rama D, ROSEN, Jeffrey M, ITTMANN, Michael, GREENBERG, Norman M, SPENCER, David M

Volltext

Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulat... von FREEMAN, Kevin W, GANGULA, Rama D, WELM, Bryan E, OZEN, Mustafa, FOSTER, Barbara A, ROSEN, Jeffrey M, ITTMANN, Michael, GREENBERG, Norman M, SPENCER, David M

Volltext

Improved artificial death switches based on caspases and FADD von LIANGFEN FAN, FREEMAN, K. W, KHAN, T, PHAM, E, SPENCER, D. M

Volltext

An inducible system for the study of FGF signalling in early amphibian development von Pownall, M.E, Welm, Bryan E, Freeman, Kevin W, Spencer, David M, Rosen, Jeffrey M, Isaacs, Harry V

Volltext

Abstract B67: Targeting glutamine metabolism in neuroblastoma and Ewing's sarcoma von Olsen, Rachelle R., Mary, Michelle N., Freeman, Kevin W.

Volltext

Abstract A04: Modeling pediatric malignancies by transforming primary neural crest cells von Olsen, Rachelle R., Joel, Otero, Wallace, Kirby, Rehg, Jerold, Freeman, Kevin W.

Volltext

Abstract B37: Targeting Myc-reprogrammed glutamine metabolism for treatment of neuroblastoma von Olsen, Rachelle R., Mary-Sinclair, Michelle N., Yin, Zhirong, Freeman, Kevin W.

Volltext

Abstract A19: Transformation of primary neural crest cells to model pediatric cancers von Olsen, Rachelle R., Otero, Joel H., Garcia-Lopez, Jesus, Wallace, Kirby A., Yin, Zhirong, Freeman, Kevin W.

Volltext