Role of cholesterol and lipid organization in disease von Maxfield, Frederick R, Tabas, Ira

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Colonic organoids derived from human induced pluripotent stem cells for modeling colorectal cancer and drug testing von Crespo, Miguel, Vilar, Eduardo, Tsai, Su-Yi, Chang, Kyle, Amin, Sadaf, Srinivasan, Tara, Zhang, Tuo, Pipalia, Nina H, Chen, Huanhuan Joyce, Witherspoon, Mavee, Gordillo, Miriam, Xiang, Jenny Zhaoying, Maxfield, Frederick R, Lipkin, Steven, Evans, Todd, Chen, Shuibing

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Mitochondrial Fission Promotes the Continued Clearance of Apoptotic Cells by Macrophages von Wang, Ying, Subramanian, Manikandan, Yurdagul, Arif, Barbosa-Lorenzi, Valéria C., Cai, Bishuang, de Juan-Sanz, Jaime, Ryan, Timothy A., Nomura, Masatoshi, Maxfield, Frederick R., Tabas, Ira

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Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches von Rosenbaum, Anton I, Maxfield, Frederick R

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Cholesterol and matrisome pathways dysregulated in astrocytes and microglia von Tcw, Julia, Qian, Lu, Pipalia, Nina H, Chao, Michael J, Liang, Shuang A, Shi, Yang, Jain, Bharat R, Bertelsen, Sarah E, Kapoor, Manav, Marcora, Edoardo, Sikora, Elizabeth, Andrews, Elizabeth J, Martini, Alessandra C, Karch, Celeste M, Head, Elizabeth, Holtzman, David M, Zhang, Bin, Wang, Minghui, Maxfield, Frederick R, Poon, Wayne W, Goate, Alison M

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The endocytic pathway in microglia during health, aging and Alzheimer’s disease von Solé-Domènech, Santiago, Cruz, Dana L, Capetillo-Zarate, Estibaliz, Maxfield, Frederick R

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Metabolically Activated Adipose Tissue Macrophages Perform Detrimental and Beneficial Functions during Diet-Induced Obesity von Coats, Brittney R., Schoenfelt, Kelly Q., Barbosa-Lorenzi, Valéria C., Peris, Eduard, Cui, Chang, Hoffman, Alexandria, Zhou, Guolin, Fernandez, Sully, Zhai, Lijie, Hall, Ben A., Haka, Abigail S., Shah, Ajay M., Reardon, Catherine A., Brady, Matthew J., Rhodes, Christopher J., Maxfield, Frederick R., Becker, Lev

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Endocytosis of beta-cyclodextrins is responsible for cholesterol reduction in Niemann-Pick type C mutant cells von Rosenbaum, Anton I, Zhang, Guangtao, Warren, J. David, Maxfield, Frederick R

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Membrane domains von Mukherjee, Sushmita, Maxfield, Frederick R

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Membrane order in the plasma membrane and endocytic recycling compartment von Iaea, David B, Maxfield, Frederick R

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Sterols are mainly in the cytoplasmic leaflet of the plasma membrane and the endocytic recycling compartment in CHO cells von Mondal, Mousumi, Mesmin, Bruno, Mukherjee, Sushmita, Maxfield, Frederick R

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Exocytosis of macrophage lysosomes leads to digestion of apoptotic adipocytes and foam cell formation[S] von Haka, Abigail S., Barbosa-Lorenzi, Valéria C., Lee, Hyuek Jong, Falcone, Domenick J., Hudis, Clifford A., Dannenberg, Andrew J., Maxfield, Frederick R.

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Role of STARD4 in sterol transport between the endocytic recycling compartment and the plasma membrane von Iaea, David B, Mao, Shu, Lund, Frederik W, Maxfield, Frederick R

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Histone deacetylase inhibitor treatment dramatically reduces cholesterol accumulation in Niemann-Pick type C1 mutant human fibroblasts von Pipalia, Nina H, Cosner, Casey C, Huang, Amy, Chatterjee, Anamitra, Bourbon, Pauline, Farley, Nathan, Helquist, Paul, Wiest, Olaf, Maxfield, Frederick R

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A murine Niemann-Pick C1 I1061T knock-in model recapitulates the pathological features of the most prevalent human disease allele von Praggastis, Maria, Tortelli, Brett, Zhang, Jessie, Fujiwara, Hideji, Sidhu, Rohini, Chacko, Anita, Chen, Zhouji, Chung, Chan, Lieberman, Andrew P, Sikora, Jakub, Davidson, Cristin, Walkley, Steven U, Pipalia, Nina H, Maxfield, Frederick R, Schaffer, Jean E, Ory, Daniel S

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The formation and consequences of cholesterol-rich deposits in atherosclerotic lesions von Maxfield, Frederick R, Steinfeld, Noah, Ma, Cheng-I J

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Microglia degrade Alzheimer’s amyloid-beta deposits extracellularly via digestive exophagy von Jacquet, Rudy G., González Ibáñez, Fernando, Picard, Katherine, Funes, Lucy, Khakpour, Mohammadparsa, Gouras, Gunnar K., Tremblay, Marie-Ève, Maxfield, Frederick R., Solé-Domènech, Santiago

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Histone deacetylase inhibitors correct the cholesterol storage defect in most Niemann-Pick C1 mutant cells von Pipalia, Nina H., Subramanian, Kanagaraj, Mao, Shu, Ralph, Harold, Hutt, Darren M., Scott, Samantha M., Balch, William E., Maxfield, Frederick R.

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Membrane dynamics and organelle biogenesis-lipid pipelines and vesicular carriers von Stefan, Christopher J, Trimble, William S, Grinstein, Sergio, Drin, Guillaume, Reinisch, Karin, De Camilli, Pietro, Cohen, Sarah, Valm, Alex M, Lippincott-Schwartz, Jennifer, Levine, Tim P, Iaea, David B, Maxfield, Frederick R, Futter, Clare E, Eden, Emily R, Judith, Delphine, van Vliet, Alexander R, Agostinis, Patrizia, Tooze, Sharon A, Sugiura, Ayumu, McBride, Heidi M

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Activation of microglia acidifies lysosomes and leads to degradation of Alzheimer amyloid fibrils von Majumdar, Amitabha, Cruz, Dana, Asamoah, Nikiya, Buxbaum, Adina, Sohar, Istvan, Lobel, Peter, Maxfield, Frederick R

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