Phase I Trial of the Oral Antiangiogenesis Agent AG-013736 in Patients With Advanced Solid Tumors: Pharmacokinetic and Clinical Results von RUGO, Hope S, HERBST, Roy S, LIU, Glenn, PARK, John W, KIES, Merrill S, STEINFELDT, Heidi M, PITHAVALA, Yazdi K, REICH, Steven D, FREDDO, James L, WILDING, George

Volltext

Randomised clinical trial: anti‐viral activity of ANA773, an oral inducer of endogenous interferons acting via TLR7, in chronic HCV von Bergmann, J. F., de Bruijne, J., Hotho, D. M., de Knegt, R. J., Boonstra, A., Weegink, C. J., van Vliet, A. A., van de Wetering, J., Fletcher, S. P., Bauman, L. A., Rahimy, M., Appleman, J. R., Freddo, J. L., Janssen, H. L. A., Reesink, H. W.

Volltext

Pharmacokinetics and Pharmacodynamics of Setrobuvir, an Orally Administered Hepatitis C Virus Non-Nucleoside Analogue Inhibitor von Mallalieu, Navita L., PhD, Rahimy, Mohamad H., PhD, Crowley, Constance A., BSc, Appleman, James R., PhD, Smith, Patrick F., PharmD, Freddo, James L., MD

Volltext

Cytoreductive Surgery in Advanced Epithelial Cancer of the Ovary: The Impact of Aortic and Pelvic Lymphadenectomy von Spirtos, Nick M., Gross, Gary M., Freddo, James L., Ballon, Samuel C.

Volltext

Potent immune activation in chronic hepatitis C patients upon administration of an oral inducer of endogenous interferons that acts via Toll-like receptor 7 von BOONSTRA, Andre, LIU, Bi-Sheng, BAUMAN, Lisa A, RAHIMY, Mohamad, APPLEMAN, James R, FREDDO, James L, REESINK, Hendrik W, DE KNEGT, Robert J, JANSSEN, Harry La, GROOTHUISMINK, Zwier Ma, BERGMANN, Jilling F, DE BRUIJNE, Joep, HOTHO, Daphne M, HANSEN, Bettina E, VLIET, Andre A.van, DE WETERING DE ROOIJ, Jeroen Van, FLETCHER, Simon P

Volltext

ENVASARC: A pivotal trial of envafolimab, and envafolimab in combination with ipilimumab, in patients with advanced or metastatic undifferentiated pleomorphic sarcoma or myxofibros... von D'Angelo, Sandra P., Robinson, Steven Ian, Lam, Joelle, Adams, Bonne J., Freddo, James L., Theuer, Charles P., Maki, Robert G

Volltext

Characterization of sulfated glucuronic acid containing glycolipids reacting with IgM M-proteins in patients with neuropathy von Ariga, T, Kohriyama, T, Freddo, L, Latov, N, Saito, M, Kon, K, Ando, S, Suzuki, M, Hemling, M E, Rinehart, K L

Volltext

Profiles of women age 30-39 and age less than 30 with epithelial ovarian cancer von PLAXE, S. C, BRALY, P. S, FREDDO, J. L, MCCLAY, E, KIRMANI, S, HOWELL, S. B

Volltext

ENVASARC: A pivotal trial of envafolimab and envafolimab in combination with ipilimumab in patients with advanced or metastatic undifferentiated pleomorphic sarcoma or myxofibrosar... von Riedel, Richard F., Chawla, Sant P., Druta, Mihaela, Jones, Robin Lewis, Schuetze, Scott, Lam, Joelle, Zhuang, Dongliang, Freddo, James L., Adams, Bonne J., Theuer, Charles P., D'Angelo, Sandra P.

Volltext

Phase I and pharmacokinetic study of intraperitoneal topotecan von PLAXE, S. C, CHRISTEN, R. D, O'QUIGLEY, J, BRALY, P. S, FREDDO, J. L, MCCLAY, E, HEATH, D, HOWELL, S. B

Volltext

Preliminary safety, pharmacokinetics (PK), pharmacodynamics (PD) and clinical efficacy of uliledlimab (TJ004309), a differentiated CD73 antibody, in combination with atezolizumab i... von Robert, Francisco, Dumbrava, Ecaterina Elena, Xing, Yan, Mills, Elizabeth, Freddo, James L., Theuer, Charles P., Adams, Bonne J., Lawrence, James, Trigeiro, Alicia A, Xu, Claire, Meng, Yuan, Lee, Linda, Zhao, Yonggang, Wang, Jerry, Shen, Huaqiong Joan, Gordon, Michael S.

Volltext

Phase I/pharmacokinetic study of high-dose progesterone and doxorubicin von CHRISTEN, R. D, MCCLAY, E. F, BRALY, P. S, O'QUIGLEY, J, HOWELL, S. B, PLAXE, S. C, YEN, S. S. C, SINIL KIM, SAEEDA KIRMANI, WILGUS, L. L, HEALTH, D. D, SHALINSKY, D. R, FREDDO, J. L

Volltext

An open label phase 1/2A study to evaluate the safety, pharmacokinetics, pharmacodynamics, and preliminary efficacy of TRC253, an androgen receptor antagonist, in patients with met... von Rathkopf, Dana E., Saleh, Mansoor N., Tsai, Frank Yung-Chin, Bilen, Mehmet Asim, Rosen, Lee S., Gottardis, Marco, Infante, Jeffrey R., Adams, Bonne J., Liu, Lilian, Theuer, Charles P., Freddo, James L., Agarwal, Neeraj

Volltext

An open-label phase 1/2a study to evaluate the safety, pharmacokinetics, pharmacodynamics, and preliminary efficacy of TRC253, an androgen receptor antagonist, in patients with met... von Rathkopf, Dana E., Saleh, Mansoor N., Tsai, Frank Yung-Chin, Rosen, Lee S., Adams, Bonne J., Liu, Lilian, Theuer, Charles P., Freddo, James L., Agarwal, Neeraj

Volltext

[1,2,4]THIADIAZINE 1,1-DIOXIDE COMPOUNDS FOR LOWERING SERUM URIC ACID von JAMES L. FREDDO

Volltext bestellen

Phase I and Pharmacokinetic Study of Intraperitoneal Ormaplatin von Plaxe, Steven C., Braly, Patricia S., Freddo, James L., McClay, Edward, Christen, Randolph D., Kirmani, Saeeda, Kim, Sinil, Heath, Dennis, Howell, Stephen B.

Volltext

Phase 1 open label, dose escalation study of RXDX101, an oral pan-trk, ROS1, and ALK inhibitor, in patients with advanced solid tumors with relevant molecular alterations von De Braud, Filippo G., Pilla, Lorenzo, Niger, Monica, Damian, Silvia, Bardazza, Benedetta, Martinetti, Antonia, Pelosi, Giuseppe, Marrapese, Giovanna, Palmeri, Laura, Cerea, Giulio, Valtorta, Emanuele, Veronese, Silvio, Sartore-Bianchi, Andrea, Ardini, Elena, Martignoni, Marcella, Galvani, Arturo, Pearson, Paul, Luo, David, Freddo, James L., Siena, Salvatore

Volltext

usos de composto ou sal farmaceuticamente aceitável do mesmo von JAMES L. FREDDO

Volltext bestellen

Phase I open-label, dose-escalation study of ANA773 tosylate, an oral prodrug of a toll-like receptor-7 agonist, in patients with advanced solid tumors von Daniels, G. A., Carson, W. E., Mita, A. C., Kendra, K. L., Rahimy, M. H., Inman, D. W., Appleman, J. R., Freddo, J. L., McNeel, D. G.

Volltext

Genetic predisposition to ovarian cancer von Freddo, J L

Volltext