Plasticity and cross-talk of Interleukin 6-type cytokines von Garbers, Christoph, Hermanns, Heike M, Schaper, Fred, Müller-Newen, Gerhard, Grötzinger, Joachim, Rose-John, Stefan, Scheller, Jürgen

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Interleukin-6 acts in the fashion of a classical chemokine on monocytic cells by inducing integrin activation, cell adhesion, actin polymerization, chemotaxis, and transmigration von Clahsen, Thomas, Schaper, Fred

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The tyrosine phosphatase SHP2 increases robustness and information transfer within IL-6-induced JAK/STAT signalling von Fiebelkow, Jessica, Guendel, André, Guendel, Beate, Mehwald, Nora, Jetka, Tomasz, Komorowski, Michal, Waldherr, Steffen, Schaper, Fred, Dittrich, Anna

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Interaction of suppressor of cytokine signalling 3 with cavin-1 links SOCS3 function and cavin-1 stability von Williams, Jamie J. L., Alotaiq, Nasser, Mullen, William, Burchmore, Richard, Liu, Libin, Baillie, George S., Schaper, Fred, Pilch, Paul F., Palmer, Timothy M.

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mTORC1 inhibition restricts inflammation-associated gastrointestinal tumorigenesis in mice von Thiem, Stefan, Pierce, Thomas P, Palmieri, Michelle, Putoczki, Tracy L, Buchert, Michael, Preaudet, Adele, Farid, Ryan O, Love, Chris, Catimel, Bruno, Lei, Zhengdeng, Rozen, Steve, Gopalakrishnan, Veena, Schaper, Fred, Hallek, Michael, Boussioutas, Alex, Tan, Patrick, Jarnicki, Andrew, Ernst, Matthias

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The multi-site docking protein Grb2-associated binder 1 (Gab1) enhances interleukin-6-induced MAPK-pathway activation in an SHP2-, Grb2-, and time-dependent manner von Bongartz, Hannes, Gille, Karen, Hessenkemper, Wiebke, Mandel, Katharina, Lewitzky, Marc, Feller, Stephan M, Schaper, Fred

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A new mechanism for the regulation of Gab1 recruitment to the plasma membrane von Eulenfeld, René, Schaper, Fred

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Intragenic regulation of SOCS3 isoforms von Klepsch, Oliver, Namer, Lise Sarah, Köhler, Nadine, Kaempfer, Raymond, Dittrich, Anna, Schaper, Fred

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Activation of STAT3 by IL-6 and IL-10 in Primary Human Macrophages Is Differentially Modulated by Suppressor of Cytokine Signaling 3 von Niemand, Claudia, Nimmesgern, Ariane, Haan, Serge, Fischer, Patrick, Schaper, Fred, Rossaint, Rolf, Heinrich, Peter C, Muller-Newen, Gerhard

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SOCS3 Exerts Its Inhibitory Function on Interleukin-6 Signal Transduction through the SHP2 Recruitment Site of gp130 von Schmitz, Jochen, Weissenbach, Manuela, Haan, Serge, Heinrich, Peter C., Schaper, Fred

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The multi-site docking protein Gab1 is constitutively phosphorylated independent from its recruitment to the plasma membrane in Jak2-V617F-positive cells and mediates proliferation... von Bongartz, Hannes, Hessenkemper, Wiebke, Müller, Christian, Fensky, Melissa, Fritsch, Johannes, Mandel, Katharina, Behrmann, Iris, Haan, Claude, Fischer, Thomas, Feller, Stephan M., Schaper, Fred

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Interleukin-6: Biology, signaling and strategies of blockade von Schaper, Fred, Rose-John, Stefan

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Response to IL-6 trans- and IL-6 classic signalling is determined by the ratio of the IL-6 receptor α to gp130 expression: fusing experimental insights and dynamic modelling von Reeh, Heike, Rudolph, Nadine, Billing, Ulrike, Christen, Henrike, Streif, Stefan, Bullinger, Eric, Schliemann-Bullinger, Monica, Findeisen, Rolf, Schaper, Fred, Huber, Heinrich J, Dittrich, Anna

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SHP2 and SOCS3 Contribute to Tyr-759-dependent Attenuation of Interleukin-6 Signaling through gp130 von Lehmann, Ute, Schmitz, Jochen, Weissenbach, Manuela, Sobota, Radoslaw M., Hörtner, Michael, Friederichs, Kerstin, Behrmann, Iris, Tsiaris, William, Sasaki, Atsuo, Schneider-Mergener, Jens, Yoshimura, Akihiko, Neel, Benjamin G., Heinrich, Peter C., Schaper, Fred

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Self-organization and regulation of intrinsically disordered proteins with folded N-termini von Simister, Philip C, Schaper, Fred, O'Reilly, Nicola, McGowan, Simon, Feller, Stephan M

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Systems biology of IL-6, IL-12 family cytokines von Dittrich, Anna, Hessenkemper, Wiebke, Schaper, Fred

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Regulation of rat heme oxygenase-1 expression by interleukin-6 via the Jak/STAT pathway in hepatocytes von Tron, Kyrylo, Samoylenko, Anatoly, Musikowski, Gernot, Kobe, Fritz, Immenschuh, Stephan, Schaper, Fred, Ramadori, Giuliano, Kietzmann, Thomas

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Expression of suppressors of cytokine signaling during liver regeneration von Campbell, J S, Prichard, L, Schaper, F, Schmitz, J, Stephenson-Famy, A, Rosenfeld, M E, Argast, G M, Heinrich, P C, Fausto, N

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Hepatic acute phase proteins – Regulation by IL-6- and IL-1-type cytokines involving STAT3 and its crosstalk with NF-κB-dependent signaling von Bode, Johannes G., Albrecht, Ute, Häussinger, Dieter, Heinrich, Peter C., Schaper, Fred

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Non‐canonical STAT3 function reduces REDD1 transcription von Köhler, Nadine, Wundrack, Nicole, Schulz, Svenja, Bartonitz, Florian, Schaper, Fred, Dittrich, Anna

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